Bret Freudenthal
@freudlab.bsky.social
Professor studying the interplay between DNA damage and human health. WY➡️CSU➡️UI➡️NIEHS➡️KU. Personal posts from science to society.
Reposted by Bret Freudenthal
Minneapolis public schools canceled classes officials after Roosevelt High School said armed Border Patrol officers came on school property during dismissal Wednesday and began tackling people, handcuffed two staff members and released chemical weapons on bystanders
www.mprnews.org/story/2026/0...
www.mprnews.org/story/2026/0...
Minneapolis schools cancel classes after Border Patrol clash disrupts dismissal at Roosevelt
Minneapolis schools closed for the week citing safety concerns after an encounter involving armed Border Patrol agents near Roosevelt High School.
www.mprnews.org
January 8, 2026 at 1:13 PM
Minneapolis public schools canceled classes officials after Roosevelt High School said armed Border Patrol officers came on school property during dismissal Wednesday and began tackling people, handcuffed two staff members and released chemical weapons on bystanders
www.mprnews.org/story/2026/0...
www.mprnews.org/story/2026/0...
Reposted by Bret Freudenthal
Is NHEJ truly a double-strand break repair pathway...repairing both strands, at the same time?
December 16, 2025 at 5:36 PM
Is NHEJ truly a double-strand break repair pathway...repairing both strands, at the same time?
Reposted by Bret Freudenthal
📢 Telomere community: Registration and abstract submission are now open for the EMBO Workshop “Telomere function and maintenance in health and disease”, May 25–30, 2026, in Lazise, Italy 🇮🇹. Looking forward to an exciting meeting! Please re-post. meetings.embo.org/event/26-tel...
Telomere function and maintenance in health and disease
Telomeres are specialized structures that protect the ends of linear chromosomes in eukaryotes. Research in this area has revealed that telomere maintenance is critical for stem cell function and nor…
meetings.embo.org
December 15, 2025 at 5:57 PM
📢 Telomere community: Registration and abstract submission are now open for the EMBO Workshop “Telomere function and maintenance in health and disease”, May 25–30, 2026, in Lazise, Italy 🇮🇹. Looking forward to an exciting meeting! Please re-post. meetings.embo.org/event/26-tel...
Reposted by Bret Freudenthal
Amazing to see the C-Trap in action! We’re proud that the C-Trap plays a part in supporting cancer research in
@freudlab.bsky.social lab at @kucancercenter.bsky.social! 🙌
@freudlab.bsky.social lab at @kucancercenter.bsky.social! 🙌
Grateful to host Sen. Moran and NIH Director Jay Bhattacharyya in the lab today. Proud of our trainees, who showcased their work using the @lumicks.bsky.social C-Trap and the KU Cryo-EM Facility. Their dedication shows how federal investment drives cancer research at @kucancercenter.bsky.social.
November 25, 2025 at 7:16 AM
Amazing to see the C-Trap in action! We’re proud that the C-Trap plays a part in supporting cancer research in
@freudlab.bsky.social lab at @kucancercenter.bsky.social! 🙌
@freudlab.bsky.social lab at @kucancercenter.bsky.social! 🙌
Grateful to host Sen. Moran and NIH Director Jay Bhattacharyya in the lab today. Proud of our trainees, who showcased their work using the @lumicks.bsky.social C-Trap and the KU Cryo-EM Facility. Their dedication shows how federal investment drives cancer research at @kucancercenter.bsky.social.
November 22, 2025 at 1:53 PM
Grateful to host Sen. Moran and NIH Director Jay Bhattacharyya in the lab today. Proud of our trainees, who showcased their work using the @lumicks.bsky.social C-Trap and the KU Cryo-EM Facility. Their dedication shows how federal investment drives cancer research at @kucancercenter.bsky.social.
Reposted by Bret Freudenthal
Thrilled to share that the final piece of my PhD work is now on bioRxiv! biorxiv.org/content/10.1... With support from @nvidia and the @NSF, we used AlphaFold to screen 1.6M+ protein pairs, revealing thousands of potential novel PPIs. All data can be viewed at predictomes.org/hp
Proteome-wide in silico screening for human protein-protein interactions
Protein-protein interactions (PPIs) drive virtually all biological processes, yet most PPIs have not been identified and even more remain structurally unresolved. We developed a two-step computational...
biorxiv.org
November 12, 2025 at 9:26 PM
Thrilled to share that the final piece of my PhD work is now on bioRxiv! biorxiv.org/content/10.1... With support from @nvidia and the @NSF, we used AlphaFold to screen 1.6M+ protein pairs, revealing thousands of potential novel PPIs. All data can be viewed at predictomes.org/hp
Reposted by Bret Freudenthal
They’ve laid off so many people that the government is now getting its economic data from DoorDash.
November 12, 2025 at 1:09 AM
They’ve laid off so many people that the government is now getting its economic data from DoorDash.
Reposted by Bret Freudenthal
Check out the perspective my lab wrote with @freudlab.bsky.social. We provide our perspective on recent work describing the structural basis of chromatin-based base excision repair!
🎉 Joint paper from the Freudenthal and @tmweaver.bsky.social Labs!
Abbey Vito’s first publication discusses a tug-of-war between BER enzymes and chromatin for access to damaged DNA, a battle central to genome stability.
Built on Tyler's foundational work! tinyurl.com/ywkt2bt5
Abbey Vito’s first publication discusses a tug-of-war between BER enzymes and chromatin for access to damaged DNA, a battle central to genome stability.
Built on Tyler's foundational work! tinyurl.com/ywkt2bt5
Base excision repair in chromatin: A tug-of-war for DNA damage
Base excision repair (BER) is a genome surveillance pathway responsible for repairing DNA base lesions distributed throughout the chromatinized eukary…
tinyurl.com
November 4, 2025 at 11:10 AM
Check out the perspective my lab wrote with @freudlab.bsky.social. We provide our perspective on recent work describing the structural basis of chromatin-based base excision repair!
🎉 Joint paper from the Freudenthal and @tmweaver.bsky.social Labs!
Abbey Vito’s first publication discusses a tug-of-war between BER enzymes and chromatin for access to damaged DNA, a battle central to genome stability.
Built on Tyler's foundational work! tinyurl.com/ywkt2bt5
Abbey Vito’s first publication discusses a tug-of-war between BER enzymes and chromatin for access to damaged DNA, a battle central to genome stability.
Built on Tyler's foundational work! tinyurl.com/ywkt2bt5
Base excision repair in chromatin: A tug-of-war for DNA damage
Base excision repair (BER) is a genome surveillance pathway responsible for repairing DNA base lesions distributed throughout the chromatinized eukary…
tinyurl.com
November 3, 2025 at 3:47 PM
🎉 Joint paper from the Freudenthal and @tmweaver.bsky.social Labs!
Abbey Vito’s first publication discusses a tug-of-war between BER enzymes and chromatin for access to damaged DNA, a battle central to genome stability.
Built on Tyler's foundational work! tinyurl.com/ywkt2bt5
Abbey Vito’s first publication discusses a tug-of-war between BER enzymes and chromatin for access to damaged DNA, a battle central to genome stability.
Built on Tyler's foundational work! tinyurl.com/ywkt2bt5
It was wonderful hosting you for the seminar visit! Also appreciate you being a good sport for having an anglerfish introduce you.🤣
Thanks @freudlab.bsky.social for the kind invitation at @kumedcenter.bsky.social BMB. 😁
November 2, 2025 at 12:03 AM
It was wonderful hosting you for the seminar visit! Also appreciate you being a good sport for having an anglerfish introduce you.🤣
🎃 Happy Halloween from the Freudenthal Lab! 🐟🖤
Anglerfish PI + Emo Researchers = Bioluminescent Despair #Scienceunderpressure
Anglerfish PI + Emo Researchers = Bioluminescent Despair #Scienceunderpressure
October 31, 2025 at 4:43 PM
🎃 Happy Halloween from the Freudenthal Lab! 🐟🖤
Anglerfish PI + Emo Researchers = Bioluminescent Despair #Scienceunderpressure
Anglerfish PI + Emo Researchers = Bioluminescent Despair #Scienceunderpressure
One of my favorite activities of the year is our annual pumpkin carving competition with the Bose Lab. Everyone’s pumpkins were amazing!
October 29, 2025 at 9:42 PM
One of my favorite activities of the year is our annual pumpkin carving competition with the Bose Lab. Everyone’s pumpkins were amazing!
Reposted by Bret Freudenthal
I think people adjacent to science (but who now find themselves deciding the fate of US science somehow) undervalue humility, valuing braggadocios hubris instead.
Yes it’s true that some scientific discoveries are complete paradigm changers, and we celebrate these. 1/
Yes it’s true that some scientific discoveries are complete paradigm changers, and we celebrate these. 1/
October 16, 2025 at 4:11 PM
I think people adjacent to science (but who now find themselves deciding the fate of US science somehow) undervalue humility, valuing braggadocios hubris instead.
Yes it’s true that some scientific discoveries are complete paradigm changers, and we celebrate these. 1/
Yes it’s true that some scientific discoveries are complete paradigm changers, and we celebrate these. 1/
Reposted by Bret Freudenthal
By far. Juvenile.
October 17, 2025 at 1:27 AM
By far. Juvenile.
Reposted by Bret Freudenthal
whoever did this little bit of magnificence, take a bow
October 14, 2025 at 5:48 PM
whoever did this little bit of magnificence, take a bow
Reposted by Bret Freudenthal
Spread the word if you can.
We have an unused stopped flow accessory from Applied Photophysics. We traded in our Chirascan CD instrument so we have no use for this anymore. Reach out if you are interested and can find a home for this setup. Will ofcourse only work with a Chirascan!
We have an unused stopped flow accessory from Applied Photophysics. We traded in our Chirascan CD instrument so we have no use for this anymore. Reach out if you are interested and can find a home for this setup. Will ofcourse only work with a Chirascan!
October 8, 2025 at 3:14 PM
Spread the word if you can.
We have an unused stopped flow accessory from Applied Photophysics. We traded in our Chirascan CD instrument so we have no use for this anymore. Reach out if you are interested and can find a home for this setup. Will ofcourse only work with a Chirascan!
We have an unused stopped flow accessory from Applied Photophysics. We traded in our Chirascan CD instrument so we have no use for this anymore. Reach out if you are interested and can find a home for this setup. Will ofcourse only work with a Chirascan!
The Sangre de Cristo Mountains outside Santa Fe were beautiful today! Wonderful day for a hike.
October 11, 2025 at 2:12 AM
The Sangre de Cristo Mountains outside Santa Fe were beautiful today! Wonderful day for a hike.
Reposted by Bret Freudenthal
Congratulations to our #EMGS2025 Best Oral Presentation Award Winners!
Best Student Oral Presentation
1st Place (Tied): David Schuster and Abigayle Vito
2nd Place: Foster Jacobs
Best Early Career Investigator Oral Presentation
1st Place: Elijah Newcomb
2nd Place: Lindsay Volk
Best Student Oral Presentation
1st Place (Tied): David Schuster and Abigayle Vito
2nd Place: Foster Jacobs
Best Early Career Investigator Oral Presentation
1st Place: Elijah Newcomb
2nd Place: Lindsay Volk
September 23, 2025 at 2:01 PM
Congratulations to our #EMGS2025 Best Oral Presentation Award Winners!
Best Student Oral Presentation
1st Place (Tied): David Schuster and Abigayle Vito
2nd Place: Foster Jacobs
Best Early Career Investigator Oral Presentation
1st Place: Elijah Newcomb
2nd Place: Lindsay Volk
Best Student Oral Presentation
1st Place (Tied): David Schuster and Abigayle Vito
2nd Place: Foster Jacobs
Best Early Career Investigator Oral Presentation
1st Place: Elijah Newcomb
2nd Place: Lindsay Volk
Reposted by Bret Freudenthal
The fiscal year is over.
So how was the NIH appropriation committed?
A long thread with institute by institute results about where the money went.
So how was the NIH appropriation committed?
A long thread with institute by institute results about where the money went.
a white cat is sitting on a box with the words where written on it .
ALT: a white cat is sitting on a box with the words where written on it .
media.tenor.com
October 1, 2025 at 4:08 PM
The fiscal year is over.
So how was the NIH appropriation committed?
A long thread with institute by institute results about where the money went.
So how was the NIH appropriation committed?
A long thread with institute by institute results about where the money went.
Reposted by Bret Freudenthal
The fiscal year ends tomorrow.
Here are results from NIH Reporter downloaded an hour ago.
The total amount of funding committed for FY2025 at this point is 99.0% of that for FY2024. The same difference could be due to a variety of technical factors.
1/3
Here are results from NIH Reporter downloaded an hour ago.
The total amount of funding committed for FY2025 at this point is 99.0% of that for FY2024. The same difference could be due to a variety of technical factors.
1/3
September 29, 2025 at 5:38 PM
The fiscal year ends tomorrow.
Here are results from NIH Reporter downloaded an hour ago.
The total amount of funding committed for FY2025 at this point is 99.0% of that for FY2024. The same difference could be due to a variety of technical factors.
1/3
Here are results from NIH Reporter downloaded an hour ago.
The total amount of funding committed for FY2025 at this point is 99.0% of that for FY2024. The same difference could be due to a variety of technical factors.
1/3
Thanks so much!!
September 26, 2025 at 3:16 PM
Thanks so much!!
Thanks to your incredible painting skills!
September 26, 2025 at 3:16 PM
Thanks to your incredible painting skills!
How it started: Assistant to the Professor 👨🔬✨
How it’s going: Professor mode unlocked 👨🏫
Also clear evidence that science doesn’t just build knowledge… it ages ya too. 😉
🙏Grateful to all the mentors, colleagues, trainees, friends & family who made this journey possible. I am here because you all!
How it’s going: Professor mode unlocked 👨🏫
Also clear evidence that science doesn’t just build knowledge… it ages ya too. 😉
🙏Grateful to all the mentors, colleagues, trainees, friends & family who made this journey possible. I am here because you all!
September 25, 2025 at 11:25 PM
How it started: Assistant to the Professor 👨🔬✨
How it’s going: Professor mode unlocked 👨🏫
Also clear evidence that science doesn’t just build knowledge… it ages ya too. 😉
🙏Grateful to all the mentors, colleagues, trainees, friends & family who made this journey possible. I am here because you all!
How it’s going: Professor mode unlocked 👨🏫
Also clear evidence that science doesn’t just build knowledge… it ages ya too. 😉
🙏Grateful to all the mentors, colleagues, trainees, friends & family who made this journey possible. I am here because you all!
… or is it a basement of a Wyoming “resident” in Jackson
September 23, 2025 at 3:50 PM
… or is it a basement of a Wyoming “resident” in Jackson
I mean that seems to be the priorities, maybe we need a committee for these semi-pro “activities” to ensure proper training 🤣
September 23, 2025 at 3:47 PM
I mean that seems to be the priorities, maybe we need a committee for these semi-pro “activities” to ensure proper training 🤣