Ferriol Calvet
@ferriol.bsky.social
PhD student in Cancer Genomics @bbglab.bsky.social @irbbarcelona.org
Pinned
Ferriol Calvet
@ferriol.bsky.social
· Oct 8
🚨 New paper alert!
Sex and smoking bias in the selection of somatic mutations in human bladder
www.nature.com/articles/s41...
by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)
Sex and smoking bias in the selection of somatic mutations in human bladder
www.nature.com/articles/s41...
by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)
Sex and smoking bias in the selection of somatic mutations in human bladder - Nature
Sex bias and association with smoking history identified in the landscape of driver mutations and clonal expansions in normal human bladder tissue may explain the higher bladder cancer risk in men and smokers.
www.nature.com
Very excited to share our new paper on the influence of biological sex and smoking in the clonal landscape of normal human bladder, just published in Nature.
A big thank you and congrats to all the authors, specially to @raquelbmi.bsky.social for all the shared efforts in this journey!
⬇️More info⬇️
A big thank you and congrats to all the authors, specially to @raquelbmi.bsky.social for all the shared efforts in this journey!
⬇️More info⬇️
Reposted by Ferriol Calvet
Meet our exceptional training team for #CancerEpi2026 💫
Field experts will guide you through how to use the best genomics tools and approaches to detect cancer mutations.
🗓️ 16-18 February 2026
Apply by 3 November - bursaries available
📎 bit.ly/41mRDnD
#OncSky #GeneSky #CancerSky 🧪🖥️🧬
Field experts will guide you through how to use the best genomics tools and approaches to detect cancer mutations.
🗓️ 16-18 February 2026
Apply by 3 November - bursaries available
📎 bit.ly/41mRDnD
#OncSky #GeneSky #CancerSky 🧪🖥️🧬
October 23, 2025 at 7:00 AM
Meet our exceptional training team for #CancerEpi2026 💫
Field experts will guide you through how to use the best genomics tools and approaches to detect cancer mutations.
🗓️ 16-18 February 2026
Apply by 3 November - bursaries available
📎 bit.ly/41mRDnD
#OncSky #GeneSky #CancerSky 🧪🖥️🧬
Field experts will guide you through how to use the best genomics tools and approaches to detect cancer mutations.
🗓️ 16-18 February 2026
Apply by 3 November - bursaries available
📎 bit.ly/41mRDnD
#OncSky #GeneSky #CancerSky 🧪🖥️🧬
Reposted by Ferriol Calvet
📢 Thrilled to share our latest paper, KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma, from my PhD, is now published in Cancer Research!
Explore our findings🔬🧬: aacrjournals.org/cancerres/ar...
#Epigenetics #Cancer #EwingSarcoma
Huge thanks to the team!
Explore our findings🔬🧬: aacrjournals.org/cancerres/ar...
#Epigenetics #Cancer #EwingSarcoma
Huge thanks to the team!
KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma
Abstract. Ewing Sarcoma (EwS) is a highly aggressive tumor arising in bones and soft tissues driven by the fusion oncoprotein EWSR1::FLI1. This aberrant transcription factor binds to GGAA microsatelli...
aacrjournals.org
October 14, 2025 at 7:38 PM
📢 Thrilled to share our latest paper, KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma, from my PhD, is now published in Cancer Research!
Explore our findings🔬🧬: aacrjournals.org/cancerres/ar...
#Epigenetics #Cancer #EwingSarcoma
Huge thanks to the team!
Explore our findings🔬🧬: aacrjournals.org/cancerres/ar...
#Epigenetics #Cancer #EwingSarcoma
Huge thanks to the team!
Reposted by Ferriol Calvet
A short thread. For years, I have been surprised by how much confusion our discovery of clones carrying cancer-driver mutations in normal tissues has caused in the cancer community. Typical questions like: (1) if you see these mutations in normal cells, are they really cancer drivers?... [1/4]
Our latest work is out in Nature today. In this paper, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people www.nature.com/articles/s41...
Somatic mutation and selection at population scale - Nature
A new version of nanorate DNA sequencing, with an error rate lower than five errors per billion base pairs and compatible with whole-exome and targeted capture, enables epidemiological-scale studies of somatic mutation and selection and the generation of high-resolution selection maps across coding and non-coding sites for many genes.
www.nature.com
October 9, 2025 at 3:29 PM
A short thread. For years, I have been surprised by how much confusion our discovery of clones carrying cancer-driver mutations in normal tissues has caused in the cancer community. Typical questions like: (1) if you see these mutations in normal cells, are they really cancer drivers?... [1/4]
Very excited to share our new paper on the influence of biological sex and smoking in the clonal landscape of normal human bladder, just published in Nature.
A big thank you and congrats to all the authors, specially to @raquelbmi.bsky.social for all the shared efforts in this journey!
⬇️More info⬇️
A big thank you and congrats to all the authors, specially to @raquelbmi.bsky.social for all the shared efforts in this journey!
⬇️More info⬇️
🚨 New paper alert!
Sex and smoking bias in the selection of somatic mutations in human bladder
www.nature.com/articles/s41...
by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)
Sex and smoking bias in the selection of somatic mutations in human bladder
www.nature.com/articles/s41...
by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)
Sex and smoking bias in the selection of somatic mutations in human bladder - Nature
Sex bias and association with smoking history identified in the landscape of driver mutations and clonal expansions in normal human bladder tissue may explain the higher bladder cancer risk in men and smokers.
www.nature.com
October 8, 2025 at 6:04 PM
Very excited to share our new paper on the influence of biological sex and smoking in the clonal landscape of normal human bladder, just published in Nature.
A big thank you and congrats to all the authors, specially to @raquelbmi.bsky.social for all the shared efforts in this journey!
⬇️More info⬇️
A big thank you and congrats to all the authors, specially to @raquelbmi.bsky.social for all the shared efforts in this journey!
⬇️More info⬇️
Reposted by Ferriol Calvet
Scientists have used low-error genome-sequencing methods in normal tissues from large cohorts of individuals to scan for mutations that set the stage for cancer
go.nature.com/42vakWS
go.nature.com/42vakWS
Ultra-sensitive DNA sequencing maps mutations that precede cancer
Scientists have used low-error genome-sequencing methods in normal tissues from large cohorts of individuals to scan for mutations that set the stage for cancer.
go.nature.com
October 8, 2025 at 5:27 PM
Scientists have used low-error genome-sequencing methods in normal tissues from large cohorts of individuals to scan for mutations that set the stage for cancer
go.nature.com/42vakWS
go.nature.com/42vakWS
Reposted by Ferriol Calvet
🧪 Out in @nature.com: Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk.
✍️ #IRBBarcelona & University of Washington
➡️ bit.ly/42wcIN5
📌 DOI: 10.1038/s41586-025-09521-x
#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social
🧵👇
✍️ #IRBBarcelona & University of Washington
➡️ bit.ly/42wcIN5
📌 DOI: 10.1038/s41586-025-09521-x
#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social
🧵👇
October 8, 2025 at 3:01 PM
🧪 Out in @nature.com: Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk.
✍️ #IRBBarcelona & University of Washington
➡️ bit.ly/42wcIN5
📌 DOI: 10.1038/s41586-025-09521-x
#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social
🧵👇
✍️ #IRBBarcelona & University of Washington
➡️ bit.ly/42wcIN5
📌 DOI: 10.1038/s41586-025-09521-x
#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social
🧵👇
Reposted by Ferriol Calvet
New research from team PROMINENT (@nlbigas.bsky.social), published in @nature.com, uncovers clues why men face a higher risk of bladder cancer and reveals that tobacco smoke acts as a promoter, not an initiator, in bladder cancer development.
Read more: www.cancergrandchallenges.org/news/early-c...
Read more: www.cancergrandchallenges.org/news/early-c...
October 8, 2025 at 3:15 PM
New research from team PROMINENT (@nlbigas.bsky.social), published in @nature.com, uncovers clues why men face a higher risk of bladder cancer and reveals that tobacco smoke acts as a promoter, not an initiator, in bladder cancer development.
Read more: www.cancergrandchallenges.org/news/early-c...
Read more: www.cancergrandchallenges.org/news/early-c...
Reposted by Ferriol Calvet
Join us for hands-on training in Cancer Genomic Epidemiology! #CancerEpi2026
Gain the expertise to use the tools and approaches to detect cancer mutations, and inform equitable prevention.
🗓️ 16-18 February 2026
Apply by 3 November - bursaries available
📎 bit.ly/41mRDnD
#OncSky #GeneSky 🧪🖥️🧬
Gain the expertise to use the tools and approaches to detect cancer mutations, and inform equitable prevention.
🗓️ 16-18 February 2026
Apply by 3 November - bursaries available
📎 bit.ly/41mRDnD
#OncSky #GeneSky 🧪🖥️🧬
September 15, 2025 at 7:00 AM
Join us for hands-on training in Cancer Genomic Epidemiology! #CancerEpi2026
Gain the expertise to use the tools and approaches to detect cancer mutations, and inform equitable prevention.
🗓️ 16-18 February 2026
Apply by 3 November - bursaries available
📎 bit.ly/41mRDnD
#OncSky #GeneSky 🧪🖥️🧬
Gain the expertise to use the tools and approaches to detect cancer mutations, and inform equitable prevention.
🗓️ 16-18 February 2026
Apply by 3 November - bursaries available
📎 bit.ly/41mRDnD
#OncSky #GeneSky 🧪🖥️🧬
Reposted by Ferriol Calvet
New paper from our lab - @bbglab.bsky.social.
Oncodrive3D: fast and accurate detection of structural clusters of somatic mutations under positive selection
academic.oup.com/nar/article/...
Kudos to Stefano, Olivia, @fmuinos.bsky.social and Abel
Oncodrive3D: fast and accurate detection of structural clusters of somatic mutations under positive selection
academic.oup.com/nar/article/...
Kudos to Stefano, Olivia, @fmuinos.bsky.social and Abel
Oncodrive3D: fast and accurate detection of structural clusters of somatic mutations under positive selection
Abstract. Identifying the genes capable of driving tumorigenesis in different tissues is one of the central goals of cancer genomics. Computational methods
academic.oup.com
August 14, 2025 at 1:10 PM
New paper from our lab - @bbglab.bsky.social.
Oncodrive3D: fast and accurate detection of structural clusters of somatic mutations under positive selection
academic.oup.com/nar/article/...
Kudos to Stefano, Olivia, @fmuinos.bsky.social and Abel
Oncodrive3D: fast and accurate detection of structural clusters of somatic mutations under positive selection
academic.oup.com/nar/article/...
Kudos to Stefano, Olivia, @fmuinos.bsky.social and Abel
Reposted by Ferriol Calvet
Back after a few days in Lisbon for the annual #EACR2025 conference! Inspiring and great science. Glad for the opportunity to present our work, coming home with a bunch of new ideas! @bbglab.bsky.social @ferriol.bsky.social
June 20, 2025 at 3:11 PM
Back after a few days in Lisbon for the annual #EACR2025 conference! Inspiring and great science. Glad for the opportunity to present our work, coming home with a bunch of new ideas! @bbglab.bsky.social @ferriol.bsky.social
Reposted by Ferriol Calvet
Kudos to @raquelbmi.bsky.social and @ferriol.bsky.social, first authors of the study, for the insane amount of good work put into this.
May 22, 2025 at 7:36 AM
Kudos to @raquelbmi.bsky.social and @ferriol.bsky.social, first authors of the study, for the insane amount of good work put into this.
Reposted by Ferriol Calvet
We are searching for a Bioinformatics Software Developer to work in Cancer Genomics:
recruitment.irbbarcelona.org/jobs/5793638...
recruitment.irbbarcelona.org/jobs/5793638...
Bioinformatics Software Developer in Cancer Genomics (ref. LAB/25/06) - IRB Barcelona
IRB Barcelona is seeking a talented and motivated Bioinformatics Software Developer (Research Assistant) to join the Biomedical Genomics Lab led by Dr. Núria López-Bigas at IRB Barcelona (bbglab.ir...
recruitment.irbbarcelona.org
April 9, 2025 at 11:50 AM
We are searching for a Bioinformatics Software Developer to work in Cancer Genomics:
recruitment.irbbarcelona.org/jobs/5793638...
recruitment.irbbarcelona.org/jobs/5793638...
Reposted by Ferriol Calvet
🚀 Our new paper is out! The BioGenome Portal: an open-source customizable platform for managing biodiversity genomics data 🧬🌍
doi.org/10.1093/narg...
@crg.eu @rodericguigo.bsky.social
#genomics #biodiversity
doi.org/10.1093/narg...
@crg.eu @rodericguigo.bsky.social
#genomics #biodiversity
The BioGenome Portal: a web-based platform for biodiversity genomics data management
Abstract. Biodiversity genomics projects are underway with the aim of sequencing the genomes of all eukaryotic species on Earth. Here we describe the BioGe
academic.oup.com
March 22, 2025 at 6:30 PM
🚀 Our new paper is out! The BioGenome Portal: an open-source customizable platform for managing biodiversity genomics data 🧬🌍
doi.org/10.1093/narg...
@crg.eu @rodericguigo.bsky.social
#genomics #biodiversity
doi.org/10.1093/narg...
@crg.eu @rodericguigo.bsky.social
#genomics #biodiversity
Reposted by Ferriol Calvet
Will the world of short-read Next-Generation Sequencing change forever? We are about to find out! #Roche #SBX #ShortReads #NovaSeqKiller
February 20, 2025 at 5:01 PM
Will the world of short-read Next-Generation Sequencing change forever? We are about to find out! #Roche #SBX #ShortReads #NovaSeqKiller
Reposted by Ferriol Calvet
“The leaders of the Human Genome Project always knew they were just starting a conversation”
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do
https://go.nature.com/3CupmSS
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do
https://go.nature.com/3CupmSS
‘Dark proteins’ hiding in our cells could hold clues to cancer and other diseases
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do.
go.nature.com
January 29, 2025 at 11:09 AM
“The leaders of the Human Genome Project always knew they were just starting a conversation”
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do
https://go.nature.com/3CupmSS
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do
https://go.nature.com/3CupmSS
Reposted by Ferriol Calvet
📣 Two ERC-funded positions are available in the lab! If you are interested in exploring the mechanisms underlying mutation, we’d love to hear from you.
PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB
RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs
PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB
RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs
November 25, 2024 at 11:19 AM
📣 Two ERC-funded positions are available in the lab! If you are interested in exploring the mechanisms underlying mutation, we’d love to hear from you.
PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB
RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs
PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB
RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs
Reposted by Ferriol Calvet
We recently announced a dual new release of intOGen and boostDM
Computational analysis of 33,218 tumor genomes to identify cancer genes and driver mutations
➡️ Compendium of Cancer Driver Genes - www.intogen.org
➡️ In Silico Saturation Mutagenesis of Cancer Genes - www.intogen.org/boostdm
Computational analysis of 33,218 tumor genomes to identify cancer genes and driver mutations
➡️ Compendium of Cancer Driver Genes - www.intogen.org
➡️ In Silico Saturation Mutagenesis of Cancer Genes - www.intogen.org/boostdm
November 25, 2024 at 3:37 AM
We recently announced a dual new release of intOGen and boostDM
Computational analysis of 33,218 tumor genomes to identify cancer genes and driver mutations
➡️ Compendium of Cancer Driver Genes - www.intogen.org
➡️ In Silico Saturation Mutagenesis of Cancer Genes - www.intogen.org/boostdm
Computational analysis of 33,218 tumor genomes to identify cancer genes and driver mutations
➡️ Compendium of Cancer Driver Genes - www.intogen.org
➡️ In Silico Saturation Mutagenesis of Cancer Genes - www.intogen.org/boostdm