Today, Nuria López-Bigas @nlbigas.bsky.social and Mònica Sánchez-Guixé @guixe-m.bsky.social are at the #BarcelonaBiomed Conference, organised by #IRBBarcelona.
A great occasion to share our projects related to childhood cancers.

Just kicked off the #BarcelonaBioMed Conference “When Development Meets #Cancer-Origins, Models & Therapies in #ChildhoodCancer”

Excited to hear from an outstanding line-up of speakers!

Organized by #IRBBarcelona & @sjdhospitalbarcelona.org

With the support of Fundación @bbvaenespana.bsky.social

Last week, @irbbarcelona.org met with the Chair of our External Advisory Board, Edwin Cuppen, to discuss the project's progress. We reflected on lessons learned from the process of clinical implementation of genomic profiling, and prepared for the next Board meeting that will happen in the new year.

Delighted and honored to have hosted the 3rd PROMINENT Retreat in Barcelona.
The @cancergrand.bsky.social project led by Allan Balmain, Paul Brennan and Nuria Lopez-Bigas, is progressing thanks to the excellent science being performed by all the teams. Great meeting and best participants!

🧪 The #IRBBarcelona #PhD Call is now open! We are offering PhD #fellowships to talented young scientists from around the world who wish to pursue a doctoral degree in #biomedicine!

Learn more and apply now!

General call ➡️ https://bit.ly/3LtzIXi
IRB DRIVE call ➡️ https://bit.ly/4hODx5B

Interested in doing a #PhD at the #IRBBarcelona? Below is one of the ways you can do so - read for more information!

#computationalbiology #biomedicalscience #biomedicine #biomedical #graduateprogram #research

Dr. @nlbigas.bsky.social, has been awarded the Rei Jaume I Prize in Biomedical Research —one of Spain’s highest scientific honours— for her pioneering work on #cancer mutations & the creation of computational tools to study them.

▶️ https://www.youtube.com/watch?v=OHmrJVtSnqg

@bbglab.bsky.social

Don't miss our extraordinary #seminar to be held next week, with @jdegregori.bsky.social, from the University of Colorado Anschutz (@cuanschutz.bsky.social).

Host: Dr. @nlbigas.bsky.social (@bbglab.bsky.social, #IRBBarcelona)

Register here 👉 https://shorturl.at/n74Th

#CancerResearch

🧪

Loic Verlingue from Centre Léon Bérard presenting results from the CGI Clinics project at @myesmo.bsky.social #ESMO25 Congress 📢

🧪 Out in @nature.com:  Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk.

 ✍️ #IRBBarcelona & University of Washington

📌 DOI: 10.1038/s41586-025-09521-x

#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social

#PCBCommunity |🧪 Un estudi de @irbbarcelona.org @bbglab.bsky.social relaciona el tabac i el sexe biològic amb el risc de patir #càncer de bufeta.

👩‍🔬 La recerca, liderada per @nlbigas.bsky.social i Abel Gonzalez-Perez, obre la porta al desenvolupament de noves eines de #prevenció i #detecció precoç.

Ultra-sensitive DNA sequencing maps mutations that precede cancer @nature.com @imartincorena.bsky.social
www.nature.com/articles/d41...
www.nature.com/articles/s41...
www.nature.com/articles/s41... @bbglab.bsky.social @irbbarcelona.org @nlbigas.bsky.social

🧪 Out in @nature.com:  Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk.

 ✍️ #IRBBarcelona & University of Washington

📌 DOI: 10.1038/s41586-025-09521-x

Video credits: 3CatInfo, Som3cat

#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.socialky.app/profile/did:plc:h4oarsknsugjli3piiechbzh" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky-mention">@bbglab.bsky.social

🚨 New paper alert!

Sex and smoking bias in the selection of somatic mutations in human bladder

www.nature.com/articles/s41...

by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)

Ferriol Calvet and Raquel Blanco (on the left), PhD students at the @bbglab.bsky.social at #IRBBarcelona, are the first authors of this study.

📝 @nature.com (2025)-DOI: 10.1038/s41586-025-09521-x

#IRBScience #CancerResearch

🧪

🗣️ Dr. @nlbigas.bsky.social: “Healthy tissues accumulate many mutations throughout life, but what matters is not only how many there are, but which ones manage to outgrow the others and expand into clones, which are copies of the same cell carrying the same mutations.”

Researchers led by Dr. @nlbigas.bsky.social & Dr. Abel González-Pérez at #IRBBarcelona, and Dr. Rosana Risques at the University of Washington, have shown that #smoking and biological sex influence how normal cells evolve in healthy bladder tissue.

🧪 Out in @nature.com: Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk.

✍️ #IRBBarcelona & University of Washington

➡️ bit.ly/42wcIN5

📌 DOI: 10.1038/s41586-025-09521-x

#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social

🧵👇

Glad to share our latest paper in our web:

bbglab.irbbarcelona.org/2025/08/3d-c...

What is molecular profiling, and how is it reshaping cancer treatment? 🧬

Our latest video explains how analysing the genetic makeup of tumours helps predict treatment response and personalise care for better patient outcomes.

📽️ zenodo.org/records/1584...

New paper from our lab - ‪@bbglab.bsky.social‬.

Oncodrive3D: fast and accurate detection of structural clusters of somatic mutations under positive selection

academic.oup.com/nar/article/...

Kudos to Stefano, Olivia, @fmuinos.bsky.social and Abel

🧪 El proyecto internacional PROMINENT, coliderado por la Dra. @nlbigas.bsky.social (@bbglab.bsky.social, #IRBBarcelona), estudia la relación entre tumores primarios y secundarios en pacientes pediátricos.

➡️ https://shorturl.at/WkIR3

#CancerResearch #ContraElCáncer

At #IRBBarcelona we celebrate #Pride by reaffirming our commitment to #diversity, #equity & #inclusion. Our Pride Info Get-Together united the community to support our #LGBTQIA+ colleagues & embrace every identity. Science thrives when everyone belongs.

Happy Pride! 🌈

youtube.com/shorts/pAZMT...

Today our colleague Bet Figuerola @efigbo.bsky.social , presented her work on the genomics analysis of a singular cancer patient at the Node Seminar session of #IRBBarcelona.
Genomics helps us to understand the origins and evolution of cancer contributing to knowledge with possible clinical impact.

Back after a few days in Lisbon for the annual #EACR2025 conference! Inspiring and great science. Glad for the opportunity to present our work, coming home with a bunch of new ideas! @bbglab.bsky.social @ferriol.bsky.social