Félix de Carpentier
@fdecarpentier.bsky.social
Postdoctoral researcher at UC Berkeley | Microalgae, environmental stress, molecular and synthetic biology | Formerly @ Université Paris Sud, Sorbonne Université, AgroParisTech, and ISA Lille.
https://scholar.google.com/citations?user=f5eOF_YAAAAJ
https://scholar.google.com/citations?user=f5eOF_YAAAAJ
Reposted by Félix de Carpentier
New paper is online! We used single cell RNA-seq & phylogenetics to identify 2 additional cell type specific TFs that control late-stage vinca alkaloid biosynthesis. The key insights originated from Camptotheca, another species that produces alkaloids. doi.org/10.1111/nph.... #PlantScience #SecMet
November 10, 2025 at 1:29 PM
New paper is online! We used single cell RNA-seq & phylogenetics to identify 2 additional cell type specific TFs that control late-stage vinca alkaloid biosynthesis. The key insights originated from Camptotheca, another species that produces alkaloids. doi.org/10.1111/nph.... #PlantScience #SecMet
Reposted by Félix de Carpentier
Wound healing is a hallmark feature of all life, including single cells. In a new preprint, Ambika Nadkarni @biochembika.bsky.social investigates a new dimension in cellular wound healing: how cells recover AFTER the wound has been closed
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 10, 2025 at 5:47 PM
Wound healing is a hallmark feature of all life, including single cells. In a new preprint, Ambika Nadkarni @biochembika.bsky.social investigates a new dimension in cellular wound healing: how cells recover AFTER the wound has been closed
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Félix de Carpentier
Are you looking for a PhD in Plant Science? Check our our project on barley canopy architecture. Combine genetics and physics to understand how awns influence barley grain development. Find out more here: lnkd.in/eWhWammJ Apply by 14th December. #PhDPosition
#PlantSci @instmolplantsci.bsky.social
#PlantSci @instmolplantsci.bsky.social
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
November 10, 2025 at 1:22 PM
Are you looking for a PhD in Plant Science? Check our our project on barley canopy architecture. Combine genetics and physics to understand how awns influence barley grain development. Find out more here: lnkd.in/eWhWammJ Apply by 14th December. #PhDPosition
#PlantSci @instmolplantsci.bsky.social
#PlantSci @instmolplantsci.bsky.social
Reposted by Félix de Carpentier
❄ Fin de la première dérive test de #TaraPolarStation
La dérive aura duré 4 semaines.
Prochaine étape : poursuite des tests au #Groenland.
2e campagne de test en fin d’année en Finlande pour tester le bateau en conditions d’hivernage.
🎯 2026 : grande dérive scientifique Tara Polaris I
La dérive aura duré 4 semaines.
Prochaine étape : poursuite des tests au #Groenland.
2e campagne de test en fin d’année en Finlande pour tester le bateau en conditions d’hivernage.
🎯 2026 : grande dérive scientifique Tara Polaris I
August 12, 2025 at 2:25 PM
❄ Fin de la première dérive test de #TaraPolarStation
La dérive aura duré 4 semaines.
Prochaine étape : poursuite des tests au #Groenland.
2e campagne de test en fin d’année en Finlande pour tester le bateau en conditions d’hivernage.
🎯 2026 : grande dérive scientifique Tara Polaris I
La dérive aura duré 4 semaines.
Prochaine étape : poursuite des tests au #Groenland.
2e campagne de test en fin d’année en Finlande pour tester le bateau en conditions d’hivernage.
🎯 2026 : grande dérive scientifique Tara Polaris I
Reposted by Félix de Carpentier
Pleased to share our latest paper led by @tomlewin.bsky.social, now out in @currentbiology.bsky.social! We present the first chromosome-level genome of a phoronid and show that shared chromosomal fusions unite phoronids and bryozoans as sister groups.
www.cell.com/current-biol...
www.cell.com/current-biol...
November 7, 2025 at 4:21 PM
Pleased to share our latest paper led by @tomlewin.bsky.social, now out in @currentbiology.bsky.social! We present the first chromosome-level genome of a phoronid and show that shared chromosomal fusions unite phoronids and bryozoans as sister groups.
www.cell.com/current-biol...
www.cell.com/current-biol...
Reposted by Félix de Carpentier
Oligonucleotide design meets big data:
We present oligoN-design, a simple, reproducible and versatile open-source tool to design specific primers and probes directly from large environmental DNA datasets.
🔗 DOI: doi.org/10.1101/2025...
👉 github.com/MiguelMSandi...
We present oligoN-design, a simple, reproducible and versatile open-source tool to design specific primers and probes directly from large environmental DNA datasets.
🔗 DOI: doi.org/10.1101/2025...
👉 github.com/MiguelMSandi...
November 7, 2025 at 12:54 PM
Oligonucleotide design meets big data:
We present oligoN-design, a simple, reproducible and versatile open-source tool to design specific primers and probes directly from large environmental DNA datasets.
🔗 DOI: doi.org/10.1101/2025...
👉 github.com/MiguelMSandi...
We present oligoN-design, a simple, reproducible and versatile open-source tool to design specific primers and probes directly from large environmental DNA datasets.
🔗 DOI: doi.org/10.1101/2025...
👉 github.com/MiguelMSandi...
Reposted by Félix de Carpentier
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
November 7, 2025 at 10:44 AM
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Interesting readings on how to estimate the difficulty to analyze a multiple sequence alignment with Pythia 2.0. www.biorxiv.org/content/10.1... and www.biorxiv.org/content/10.1...
Pythia 2.0: New Data, New Prediction Model, New Features
Maximum Likelihood (ML) based phylogenetic inference is time- and resource-intensive, especially when initiating multiple independent inferences from distinct comprehensive tree topologies. Performing...
www.biorxiv.org
November 7, 2025 at 5:11 PM
Interesting readings on how to estimate the difficulty to analyze a multiple sequence alignment with Pythia 2.0. www.biorxiv.org/content/10.1... and www.biorxiv.org/content/10.1...
Reposted by Félix de Carpentier
Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from?
Today, we report the discovery of telomerase homologs in a family of antiviral reverse transcriptases, revealing an unexpected evolutionary origin in bacteria.
doi.org/10.1101/2025...
Today, we report the discovery of telomerase homologs in a family of antiviral reverse transcriptases, revealing an unexpected evolutionary origin in bacteria.
doi.org/10.1101/2025...
October 17, 2025 at 12:47 PM
Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from?
Today, we report the discovery of telomerase homologs in a family of antiviral reverse transcriptases, revealing an unexpected evolutionary origin in bacteria.
doi.org/10.1101/2025...
Today, we report the discovery of telomerase homologs in a family of antiviral reverse transcriptases, revealing an unexpected evolutionary origin in bacteria.
doi.org/10.1101/2025...
Reposted by Félix de Carpentier
Our method for genome size estimation from long-read overlaps is now published 🥳
academic.oup.com/bioinformati...
academic.oup.com/bioinformati...
Genome size estimation from long read overlaps
AbstractMotivation. Accurate genome size estimation is an important component of genomic analyses such as assembly and coverage calculation, though existin
academic.oup.com
November 7, 2025 at 3:19 AM
Our method for genome size estimation from long-read overlaps is now published 🥳
academic.oup.com/bioinformati...
academic.oup.com/bioinformati...
Reposted by Félix de Carpentier
🚨New preprint out!
We present a foundational genomic resource of human gut microbiome viruses. It delivers high-quality, deeply curated data spanning taxonomy, predicted hosts, structures, and functions, providing a reference for gut virome research. (1/8)
www.biorxiv.org/content/10.1...
We present a foundational genomic resource of human gut microbiome viruses. It delivers high-quality, deeply curated data spanning taxonomy, predicted hosts, structures, and functions, providing a reference for gut virome research. (1/8)
www.biorxiv.org/content/10.1...
November 6, 2025 at 5:26 PM
🚨New preprint out!
We present a foundational genomic resource of human gut microbiome viruses. It delivers high-quality, deeply curated data spanning taxonomy, predicted hosts, structures, and functions, providing a reference for gut virome research. (1/8)
www.biorxiv.org/content/10.1...
We present a foundational genomic resource of human gut microbiome viruses. It delivers high-quality, deeply curated data spanning taxonomy, predicted hosts, structures, and functions, providing a reference for gut virome research. (1/8)
www.biorxiv.org/content/10.1...
Reposted by Félix de Carpentier
After 5 years of waiting, the new #CRISPR classification by Makarova et al. is out @natmicrobiol.nature.com www.nature.com/articles/s41...
An updated evolutionary classification of CRISPR–Cas systems including rare variants - Nature Microbiology
An exploration of previously undescribed variants from the long tail of the CRISPR–Cas distribution.
www.nature.com
November 6, 2025 at 1:49 PM
After 5 years of waiting, the new #CRISPR classification by Makarova et al. is out @natmicrobiol.nature.com www.nature.com/articles/s41...
Reposted by Félix de Carpentier
If you're interested in using pangenome graphs for comparative genomics, check out my webinar, part of EMBL-EBI's "Concepts, methods, and resources in pangenomics" series, available on-demand: www.ebi.ac.uk/training/eve...
Pangenome graphs as a new paradigm in comparative genomics -
Pangenome graphs as a new paradigm in comparative genomics -
www.ebi.ac.uk
November 6, 2025 at 11:40 AM
If you're interested in using pangenome graphs for comparative genomics, check out my webinar, part of EMBL-EBI's "Concepts, methods, and resources in pangenomics" series, available on-demand: www.ebi.ac.uk/training/eve...
Reposted by Félix de Carpentier
Enhanced cell aggregation in the Chlamydomonas reinhardtii rbo1 mutant in response to multifactorial stress combination academic.oup.com/plphys/artic... @plantphys.bsky.social
Enhanced cell aggregation in the Chlamydomonas reinhardtii rbo1 mutant in response to multifactorial stress combination
The unicellular algae C. reinhardtii responds to multifactorial stress by forming aggregates, suggesting that multicellularity evolved as a response to mul
academic.oup.com
November 6, 2025 at 2:28 PM
Enhanced cell aggregation in the Chlamydomonas reinhardtii rbo1 mutant in response to multifactorial stress combination academic.oup.com/plphys/artic... @plantphys.bsky.social
Reposted by Félix de Carpentier
1/ It is my pleasure to share the latest preprint of the team: "Symbiotic diversification relies on an ancestral gene network in plants"
doi.org/10.1101/2025...
Here, we identified and functionally validated a novel master regulator of intracellular symbioses!
A thread ...
#PlantScience
doi.org/10.1101/2025...
Here, we identified and functionally validated a novel master regulator of intracellular symbioses!
A thread ...
#PlantScience
Symbiotic diversification relies on an ancestral gene network in plants
Symbioses have been fundamental to colonization of terrestrial ecosystems by plants and their evolution. Emergence of the ancient arbuscular mycorrhizal symbiosis was followed by the diversification o...
doi.org
November 4, 2025 at 8:06 AM
1/ It is my pleasure to share the latest preprint of the team: "Symbiotic diversification relies on an ancestral gene network in plants"
doi.org/10.1101/2025...
Here, we identified and functionally validated a novel master regulator of intracellular symbioses!
A thread ...
#PlantScience
doi.org/10.1101/2025...
Here, we identified and functionally validated a novel master regulator of intracellular symbioses!
A thread ...
#PlantScience
Reposted by Félix de Carpentier
Applications are currently being accepted for UBC's ✨️ Biodiversity Postdoctoral Fellowship ✨️ (two positions!!), due Jan. 15
Please share far and wide 🚀
(See thread)
Please share far and wide 🚀
(See thread)
Postdoctoral Fellowship Opportunities
Biodiversity Postdoctoral Fellowship, 2-year (2026-2028) - 2 positions OPENAt UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in resea...
biodiversity.ubc.ca
November 3, 2025 at 5:25 PM
Applications are currently being accepted for UBC's ✨️ Biodiversity Postdoctoral Fellowship ✨️ (two positions!!), due Jan. 15
Please share far and wide 🚀
(See thread)
Please share far and wide 🚀
(See thread)
Reposted by Félix de Carpentier
This paper has been a must! Great collaboration with @mkrupovic.bsky.social and @yifanzhou.bsky.social, a N&V by a legend of halophilic archaea tinyurl.com/yc3dcv72, and one picture of one of our expeditions to Dallol making the cover of the November issue of @natmicrobiol.nature.com
rdcu.be/eLtCH
rdcu.be/eLtCH
November 2, 2025 at 5:52 PM
This paper has been a must! Great collaboration with @mkrupovic.bsky.social and @yifanzhou.bsky.social, a N&V by a legend of halophilic archaea tinyurl.com/yc3dcv72, and one picture of one of our expeditions to Dallol making the cover of the November issue of @natmicrobiol.nature.com
rdcu.be/eLtCH
rdcu.be/eLtCH
Reposted by Félix de Carpentier
Very excited to finally share my PhD paper, about advancing #chloroplast #synbio through high-throughput plastome engineering of #Chlamydomonas.
Huge thanks to the whole team!
www.nature.com/articles/s41...
Huge thanks to the whole team!
www.nature.com/articles/s41...
November 3, 2025 at 4:26 PM
Very excited to finally share my PhD paper, about advancing #chloroplast #synbio through high-throughput plastome engineering of #Chlamydomonas.
Huge thanks to the whole team!
www.nature.com/articles/s41...
Huge thanks to the whole team!
www.nature.com/articles/s41...
Reposted by Félix de Carpentier
NEWS & VIEWS: Turning the knobs: The impact of glutathionylation on starch metabolism (Anna Moseler) doi.org/10.1093/plph... #PlantScience
October 3, 2025 at 6:46 PM
NEWS & VIEWS: Turning the knobs: The impact of glutathionylation on starch metabolism (Anna Moseler) doi.org/10.1093/plph... #PlantScience
Reposted by Félix de Carpentier
📢 We’re hiring!
The DSMZ is looking for a Scientific Lead for the SILVA Database — a unique opportunity to shape one of the world’s most important scientific resources for microbial taxonomy and ecology.
Apply now and help us shape the future of microbial research.
👉 www.dsmz.de/dsmz/career/...
The DSMZ is looking for a Scientific Lead for the SILVA Database — a unique opportunity to shape one of the world’s most important scientific resources for microbial taxonomy and ecology.
Apply now and help us shape the future of microbial research.
👉 www.dsmz.de/dsmz/career/...
November 3, 2025 at 9:52 AM
📢 We’re hiring!
The DSMZ is looking for a Scientific Lead for the SILVA Database — a unique opportunity to shape one of the world’s most important scientific resources for microbial taxonomy and ecology.
Apply now and help us shape the future of microbial research.
👉 www.dsmz.de/dsmz/career/...
The DSMZ is looking for a Scientific Lead for the SILVA Database — a unique opportunity to shape one of the world’s most important scientific resources for microbial taxonomy and ecology.
Apply now and help us shape the future of microbial research.
👉 www.dsmz.de/dsmz/career/...
Reposted by Félix de Carpentier
GcMeta - a new global resource of metagenome-assembled genomes and their encoded functions with an easy to use, interactive and searchable website academic.oup.com/nar/advance-...
gcMeta 2025: a global repository of metagenome-assembled genomes enabling cross-ecosystem microbial discovery and function research
Abstract. The rapid growth of metagenomic sequencing has generated an unprecedented wealth of metagenome-assembled genomes (MAGs), transforming opportuniti
academic.oup.com
November 3, 2025 at 9:01 AM
GcMeta - a new global resource of metagenome-assembled genomes and their encoded functions with an easy to use, interactive and searchable website academic.oup.com/nar/advance-...
Reposted by Félix de Carpentier
What looked like a hearing organ on a tiny stinkbug’s leg turned out to be something far stranger: a fungal nursery that mother bugs use to coat their newly laid eggs in protective symbiotic hyphae, shielding their offspring from parasitic wasps.
Learn more in Science: https://scim.ag/4nDrDNm
Learn more in Science: https://scim.ag/4nDrDNm
![(A) An adult female in the field on Sicyos angulatus. (B) Back view of an adult female reared on cucumber, whose hindleg organs are covered with fungal hyphae (arrowheads). (C) Magnified image of the hindleg organ. (D to L) Morphology of hind tibia of adult male [(D) to (F)], immature adult female [(G) to (I)], and mature adult female [(J) to (L)]. [(D), (G), and (I)] Brightfield images. [(E), (H), and (K)] Scanning electron microscope (SEM) images. [(F), (I), and (L)] Magnified SEM images. (M to O) Peculiar behavior of egg-laying adult female. After laying each egg (M), the female rhythmically scratches the hyphae-covered hindleg organ with tarsal claws of the opposite hindleg (N) and then rubs the egg surface with the claws in a skillful manner (O). Also see movie S1. (P to R) Egg mass covered with fungal hyphae at 0-day (P), 3-day (Q), and 10-day (R) intervals after oviposition. Reddish color of 10-day eggs reflects the body color of developing nymphs inside.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:vqgovau5gkirnk3ss5qwjdmz/bafkreiatozcclrv3q5pr2susooiojtvkwr6kwnd22hwxh3ijzh7lpi276q@jpeg)
November 1, 2025 at 9:14 PM
What looked like a hearing organ on a tiny stinkbug’s leg turned out to be something far stranger: a fungal nursery that mother bugs use to coat their newly laid eggs in protective symbiotic hyphae, shielding their offspring from parasitic wasps.
Learn more in Science: https://scim.ag/4nDrDNm
Learn more in Science: https://scim.ag/4nDrDNm
Reposted by Félix de Carpentier
A pangenome and pantranscriptome of hexaploid oat. #OatGenome #Pangenome #Pantranscriptome #HexaploidOat @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 2, 2025 at 11:31 AM
A pangenome and pantranscriptome of hexaploid oat. #OatGenome #Pangenome #Pantranscriptome #HexaploidOat @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Félix de Carpentier
My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438
@dartmouthbcb.bsky.social @futurepislack.bsky.social
@dartmouthbcb.bsky.social @futurepislack.bsky.social
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
August 27, 2025 at 8:50 PM
My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438
@dartmouthbcb.bsky.social @futurepislack.bsky.social
@dartmouthbcb.bsky.social @futurepislack.bsky.social
Reposted by Félix de Carpentier
🧬🧪Research Technician Position Open🧬🧪
HHMI, UT Austin. Biochemistry/Biophysics- Assist recombinant protein expression, purification and structural analysis (protein NMR and CryoEM) to uncover the mechanisms of cell fate specification in plants.
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
HHMI, UT Austin. Biochemistry/Biophysics- Assist recombinant protein expression, purification and structural analysis (protein NMR and CryoEM) to uncover the mechanisms of cell fate specification in plants.
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
Research Technician - Torii Lab
Primary Work Address: 2500 Speedway, Austin, TX, 78712 Current HHMI Employees, click here to apply via your Workday account. About the Lab We are currently seeking a proactive Research Technician to s...
hhmi.wd1.myworkdayjobs.com
November 1, 2025 at 7:41 PM
🧬🧪Research Technician Position Open🧬🧪
HHMI, UT Austin. Biochemistry/Biophysics- Assist recombinant protein expression, purification and structural analysis (protein NMR and CryoEM) to uncover the mechanisms of cell fate specification in plants.
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
HHMI, UT Austin. Biochemistry/Biophysics- Assist recombinant protein expression, purification and structural analysis (protein NMR and CryoEM) to uncover the mechanisms of cell fate specification in plants.
hhmi.wd1.myworkdayjobs.com/en-US/Extern...