René Inckemann
@reneinckemann.bsky.social
interested in plant #synbio,
Postdoc @stanford in the Brophy lab,
alumni @mpi_marburg @erblabs,
@gasb_synbio steering
@igemmarburg instructor 2018-2024
Postdoc @stanford in the Brophy lab,
alumni @mpi_marburg @erblabs,
@gasb_synbio steering
@igemmarburg instructor 2018-2024
Pinned
Very excited to finally share my PhD paper, about advancing #chloroplast #synbio through high-throughput plastome engineering of #Chlamydomonas.
Huge thanks to the whole team!
www.nature.com/articles/s41...
Huge thanks to the whole team!
www.nature.com/articles/s41...
Reposted by René Inckemann
New Brief Communication: "A CRISPR-based sequence proximity binding protein labelling system for scanning upstream regulatory proteins" rdcu.be/eZLUP
CRISPR-based proximity labelling system to profile DNA-binding proteins such as PIF4 transcription factor .
CRISPR-based proximity labelling system to profile DNA-binding proteins such as PIF4 transcription factor .
January 19, 2026 at 6:36 PM
New Brief Communication: "A CRISPR-based sequence proximity binding protein labelling system for scanning upstream regulatory proteins" rdcu.be/eZLUP
CRISPR-based proximity labelling system to profile DNA-binding proteins such as PIF4 transcription factor .
CRISPR-based proximity labelling system to profile DNA-binding proteins such as PIF4 transcription factor .
Reposted by René Inckemann
Why I’m genetically engineering a rainbow flower…
And how a Russian fairy tale inspired the idea 🧵
And how a Russian fairy tale inspired the idea 🧵
January 16, 2026 at 9:32 AM
Why I’m genetically engineering a rainbow flower…
And how a Russian fairy tale inspired the idea 🧵
And how a Russian fairy tale inspired the idea 🧵
Reposted by René Inckemann
Genetic engineering, painting, sculpting, floristry, and fantasy are united in @nickdesnoyer.bsky.social 's flower design art project. New essay out now on a blossoming frontier of transgenic art!
Mutating The Medium
A blooming future for biodesign
allmovingparts.substack.com
December 15, 2025 at 5:43 PM
Genetic engineering, painting, sculpting, floristry, and fantasy are united in @nickdesnoyer.bsky.social 's flower design art project. New essay out now on a blossoming frontier of transgenic art!
Reposted by René Inckemann
Pleased to share this thoughtful essay by Jess on my flower design project🌹🧬
As a small thank-you for spreading the work, I'm randomly giving away 5 of these new morphogenesis hoodies to whoever reposts this!
As a small thank-you for spreading the work, I'm randomly giving away 5 of these new morphogenesis hoodies to whoever reposts this!
December 15, 2025 at 5:51 PM
Pleased to share this thoughtful essay by Jess on my flower design project🌹🧬
As a small thank-you for spreading the work, I'm randomly giving away 5 of these new morphogenesis hoodies to whoever reposts this!
As a small thank-you for spreading the work, I'm randomly giving away 5 of these new morphogenesis hoodies to whoever reposts this!
Reposted by René Inckemann
‼️Please RT: The CEPLAS Graduate School call for 2026 is now open! Detailed info on our website: bit.ly/4q19JWk
@hhu.de @unicologne.bsky.social @mpipz.bsky.social @fz-juelich.de @leibnizipk.bsky.social @plantsciencedbg.bsky.social
@hhu.de @unicologne.bsky.social @mpipz.bsky.social @fz-juelich.de @leibnizipk.bsky.social @plantsciencedbg.bsky.social
December 9, 2025 at 2:42 PM
‼️Please RT: The CEPLAS Graduate School call for 2026 is now open! Detailed info on our website: bit.ly/4q19JWk
@hhu.de @unicologne.bsky.social @mpipz.bsky.social @fz-juelich.de @leibnizipk.bsky.social @plantsciencedbg.bsky.social
@hhu.de @unicologne.bsky.social @mpipz.bsky.social @fz-juelich.de @leibnizipk.bsky.social @plantsciencedbg.bsky.social
Reposted by René Inckemann
European plant scientists welcome the EU Trilogue Provisional Agreement on New Genomic Techniques (#NGT), as EU-SAGE reports, the network representing plants scientists at 134 European plant science institutes and societies www.eu-sage.eu/news/Europea...
www.eu-sage.eu
December 8, 2025 at 5:31 PM
European plant scientists welcome the EU Trilogue Provisional Agreement on New Genomic Techniques (#NGT), as EU-SAGE reports, the network representing plants scientists at 134 European plant science institutes and societies www.eu-sage.eu/news/Europea...
Reposted by René Inckemann
AI model Helixer predicts eukaryotic genes ab initio, directly from a plain text FASTA file.
No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.
Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com
www.nature.com/articles/s41...
No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.
Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com
www.nature.com/articles/s41...
Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model - Nature Methods
By leveraging both deep learning and hidden Markov models, Helixer achieves broad taxonomic coverage for ab initio gene annotation of eukaryotic genomes from fungi, plants, vertebrates and invertebrat...
www.nature.com
November 26, 2025 at 6:00 AM
AI model Helixer predicts eukaryotic genes ab initio, directly from a plain text FASTA file.
No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.
Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com
www.nature.com/articles/s41...
No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.
Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com
www.nature.com/articles/s41...
Reposted by René Inckemann
After 10 Fridays, 10 flowers, and 100+ drawings, the Florédex is complete! ✨
Come take a tour of the design and science behind 10 iconic flowers 🌺🧵
Come take a tour of the design and science behind 10 iconic flowers 🌺🧵
November 21, 2025 at 9:59 AM
After 10 Fridays, 10 flowers, and 100+ drawings, the Florédex is complete! ✨
Come take a tour of the design and science behind 10 iconic flowers 🌺🧵
Come take a tour of the design and science behind 10 iconic flowers 🌺🧵
Reposted by René Inckemann
New paper is online! We used single cell RNA-seq & phylogenetics to identify 2 additional cell type specific TFs that control late-stage vinca alkaloid biosynthesis. The key insights originated from Camptotheca, another species that produces alkaloids. doi.org/10.1111/nph.... #PlantScience #SecMet
November 10, 2025 at 1:29 PM
New paper is online! We used single cell RNA-seq & phylogenetics to identify 2 additional cell type specific TFs that control late-stage vinca alkaloid biosynthesis. The key insights originated from Camptotheca, another species that produces alkaloids. doi.org/10.1111/nph.... #PlantScience #SecMet
Reposted by René Inckemann
New OA Article: "A modular high-throughput approach for advancing synthetic biology in the chloroplast of Chlamydomonas" rdcu.be/eOdZP
Modular-cloning-based platform for high-throughput chloroplast engineering in Chlamydomonas reinhardtii.
Modular-cloning-based platform for high-throughput chloroplast engineering in Chlamydomonas reinhardtii.
November 4, 2025 at 1:05 PM
New OA Article: "A modular high-throughput approach for advancing synthetic biology in the chloroplast of Chlamydomonas" rdcu.be/eOdZP
Modular-cloning-based platform for high-throughput chloroplast engineering in Chlamydomonas reinhardtii.
Modular-cloning-based platform for high-throughput chloroplast engineering in Chlamydomonas reinhardtii.
Very excited to finally share my PhD paper, about advancing #chloroplast #synbio through high-throughput plastome engineering of #Chlamydomonas.
Huge thanks to the whole team!
www.nature.com/articles/s41...
Huge thanks to the whole team!
www.nature.com/articles/s41...
November 3, 2025 at 4:26 PM
Very excited to finally share my PhD paper, about advancing #chloroplast #synbio through high-throughput plastome engineering of #Chlamydomonas.
Huge thanks to the whole team!
www.nature.com/articles/s41...
Huge thanks to the whole team!
www.nature.com/articles/s41...
Reposted by René Inckemann
I am delighted to share our latest work on memory gene circuits for plants. This work was led by the phenomenal PhD student @patrickgong.bsky.social
A lot of debugging & highlights how even simple components in synthetic biology can have unexpected properties.
www.biorxiv.org/content/10.1...
A lot of debugging & highlights how even simple components in synthetic biology can have unexpected properties.
www.biorxiv.org/content/10.1...
CREation of an expanded plant memory gene circuit toolkit
Genetic circuits rely on modular, well-characterized genetic parts to achieve predictable cellular behaviour. Despite their widespread adoption, biological parts are complex and when used in a new mol...
www.biorxiv.org
October 31, 2025 at 9:24 AM
I am delighted to share our latest work on memory gene circuits for plants. This work was led by the phenomenal PhD student @patrickgong.bsky.social
A lot of debugging & highlights how even simple components in synthetic biology can have unexpected properties.
www.biorxiv.org/content/10.1...
A lot of debugging & highlights how even simple components in synthetic biology can have unexpected properties.
www.biorxiv.org/content/10.1...
Reposted by René Inckemann
Don’t miss my presentation @iGEM tomorrow at 14:00 main stage!
I will be throwing out bio-designer shirts to the back row 🧬🤘
I will be throwing out bio-designer shirts to the back row 🧬🤘
October 29, 2025 at 9:16 AM
Don’t miss my presentation @iGEM tomorrow at 14:00 main stage!
I will be throwing out bio-designer shirts to the back row 🧬🤘
I will be throwing out bio-designer shirts to the back row 🧬🤘
Reposted by René Inckemann
Genetically engineered color-changing Arabidopsis 🧬📷- attempt #3
I think I finally nailed it with this one.
I think I finally nailed it with this one.
October 27, 2025 at 11:53 AM
Genetically engineered color-changing Arabidopsis 🧬📷- attempt #3
I think I finally nailed it with this one.
I think I finally nailed it with this one.
Reposted by René Inckemann
Friday Flower 008: Tulip 🌷
Tulip’s pastel colors and waxy cuticle that scatters light give them a soft watercolor look.
The “broken” petals of Semper Augustus, created by a virus, became some of the most famous and valuable flowers in history... and their genome is 34Gb 🤯
Tulip’s pastel colors and waxy cuticle that scatters light give them a soft watercolor look.
The “broken” petals of Semper Augustus, created by a virus, became some of the most famous and valuable flowers in history... and their genome is 34Gb 🤯
October 24, 2025 at 9:04 AM
Friday Flower 008: Tulip 🌷
Tulip’s pastel colors and waxy cuticle that scatters light give them a soft watercolor look.
The “broken” petals of Semper Augustus, created by a virus, became some of the most famous and valuable flowers in history... and their genome is 34Gb 🤯
Tulip’s pastel colors and waxy cuticle that scatters light give them a soft watercolor look.
The “broken” petals of Semper Augustus, created by a virus, became some of the most famous and valuable flowers in history... and their genome is 34Gb 🤯
Reposted by René Inckemann
One of my Arabidopsis micro-roses next to its wild type sister ✨
Now just to make it rainbow 🧬...
Now just to make it rainbow 🧬...
October 22, 2025 at 4:06 PM
One of my Arabidopsis micro-roses next to its wild type sister ✨
Now just to make it rainbow 🧬...
Now just to make it rainbow 🧬...
Reposted by René Inckemann
Friday Flower 007: Petunia 💮✨
Petunias carry the active transposon dTph1, which powers mutant screens and paints stripey patterns as it jumps.
Their five petals are fused, with diverse color designs tracing the corolla’s fusion seam.
Petunias carry the active transposon dTph1, which powers mutant screens and paints stripey patterns as it jumps.
Their five petals are fused, with diverse color designs tracing the corolla’s fusion seam.
October 10, 2025 at 9:12 AM
Friday Flower 007: Petunia 💮✨
Petunias carry the active transposon dTph1, which powers mutant screens and paints stripey patterns as it jumps.
Their five petals are fused, with diverse color designs tracing the corolla’s fusion seam.
Petunias carry the active transposon dTph1, which powers mutant screens and paints stripey patterns as it jumps.
Their five petals are fused, with diverse color designs tracing the corolla’s fusion seam.
Reposted by René Inckemann
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Independent Research Fellowships Leading to Tenured Faculty Positions | John Innes Centre
The John Innes Centre (JIC), is a world leading centre of excellence in plant and microbial sciences based on the Norwich Research Park, UK. We are inviting applications from outstanding researchers…
www.jic.ac.uk
October 3, 2025 at 4:06 PM
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Reposted by René Inckemann
A tiny white-petalled weed beloved of plant biologists has received a CRISPR-fueled makeover, turning it into a supersized ruby-colored bloom www.nature.com/articles/s41...
Blooms supersized - Nature Biotechnology
Nature Biotechnology - Blooms supersized
www.nature.com
September 26, 2025 at 4:01 PM
A tiny white-petalled weed beloved of plant biologists has received a CRISPR-fueled makeover, turning it into a supersized ruby-colored bloom www.nature.com/articles/s41...
Reposted by René Inckemann
Color changing flowers 🧬🎨- attempt #2
Older flowers (bottom) show dark red/ orange tints whereas young buds (top) display strong fuchsia color. Getting closer..
Older flowers (bottom) show dark red/ orange tints whereas young buds (top) display strong fuchsia color. Getting closer..
September 21, 2025 at 12:30 PM
Color changing flowers 🧬🎨- attempt #2
Older flowers (bottom) show dark red/ orange tints whereas young buds (top) display strong fuchsia color. Getting closer..
Older flowers (bottom) show dark red/ orange tints whereas young buds (top) display strong fuchsia color. Getting closer..
Reposted by René Inckemann
Friday Flower 005: Arabidopsis thaliana 🌱✨
A tiny flower, but a giant in research, thale cress enabled our understanding of flower development through the "ABC Model".
With this knowledge, their flowers can be essentially reprogrammed to produce micro-roses 🧬🌹
A tiny flower, but a giant in research, thale cress enabled our understanding of flower development through the "ABC Model".
With this knowledge, their flowers can be essentially reprogrammed to produce micro-roses 🧬🌹
September 19, 2025 at 10:37 AM
Friday Flower 005: Arabidopsis thaliana 🌱✨
A tiny flower, but a giant in research, thale cress enabled our understanding of flower development through the "ABC Model".
With this knowledge, their flowers can be essentially reprogrammed to produce micro-roses 🧬🌹
A tiny flower, but a giant in research, thale cress enabled our understanding of flower development through the "ABC Model".
With this knowledge, their flowers can be essentially reprogrammed to produce micro-roses 🧬🌹
Reposted by René Inckemann
Friday Flower 004: Hibiscus trionum 🌺✨
Hibiscus trionum displays a dark bullseye in the center that acts as a landing pad for pollinators 🎯
The bullseye is made by a developmental boundary delineating distinct cell shapes and pigments.
Hibiscus trionum displays a dark bullseye in the center that acts as a landing pad for pollinators 🎯
The bullseye is made by a developmental boundary delineating distinct cell shapes and pigments.
September 12, 2025 at 4:51 PM
Friday Flower 004: Hibiscus trionum 🌺✨
Hibiscus trionum displays a dark bullseye in the center that acts as a landing pad for pollinators 🎯
The bullseye is made by a developmental boundary delineating distinct cell shapes and pigments.
Hibiscus trionum displays a dark bullseye in the center that acts as a landing pad for pollinators 🎯
The bullseye is made by a developmental boundary delineating distinct cell shapes and pigments.
Reposted by René Inckemann
Sneak peak of tomorrows Friday Flower! 🌺
Whoever guesses the flower correctly gets a gold star ⭐️
Whoever guesses the flower correctly gets a gold star ⭐️
September 11, 2025 at 11:52 AM
Sneak peak of tomorrows Friday Flower! 🌺
Whoever guesses the flower correctly gets a gold star ⭐️
Whoever guesses the flower correctly gets a gold star ⭐️
Reposted by René Inckemann
W1 Tenure-Track Professor for Plant Biochemistry.
Tübingen, Germany. #plantscijobs #plantscijob
uni-tuebingen.de/fakultaeten/...
Tübingen, Germany. #plantscijobs #plantscijob
uni-tuebingen.de/fakultaeten/...
JobOpportunities
uni-tuebingen.de
September 9, 2025 at 7:56 AM
W1 Tenure-Track Professor for Plant Biochemistry.
Tübingen, Germany. #plantscijobs #plantscijob
uni-tuebingen.de/fakultaeten/...
Tübingen, Germany. #plantscijobs #plantscijob
uni-tuebingen.de/fakultaeten/...