Eduardo Zimmer
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erzimmer.bsky.social
Eduardo Zimmer
@erzimmer.bsky.social
1.4K followers 1.1K following 98 posts
Researcher interested in neurodegeneration and astrocytes.

Assistant professor at UFRGS (🇧🇷), Research Associate at BraIns (🇧🇷) and Adjunct Professor at McGill (🇨🇦)

https://zimmer-lab.org/ 🌎

zimmerneurolab.bsky.social 🦋
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erzimmer.bsky.social
Eduardo Zimmer @erzimmer.bsky.social · Nov 19
I’m an Assistant Prof of Pharmacology at @ufrgs.br (🇧🇷) and an adjunct professor at McGill (🇨🇦). We study neurodegeneration, with a particular focus on astrocytes! More about the lab 👉 zimmer-lab.org 👉 Looking forward to rebuild our network here 🦋
Home Page - Zimmer Lab
zimmer-lab.org
Reposted by Eduardo Zimmer
zimmerneurolab.bsky.social
Just published in Nat. Neurosci.

Led by J.P. Ferrari-Souza, this study used imaging & fluid biomarkers to reveal that microglia modulate Aβ-related astrocyte reactivity, which in turn contributes to AD progression.

@erzimmer.bsky.social
@natureportfolio.nature.com

www.nature.com/articles/s41...
Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer’s disease - Nature Neuroscience
Microglia influence amyloid-β effects on astrocyte reactivity in the living brain of individuals with Alzheimer’s disease. This phenomenon further contributes to cognitive impairment via tau phosphory...
www.nature.com
November 7, 2025 at 10:16 AM
Reposted by Eduardo Zimmer
sdas617.bsky.social
Another reason to study developmental biology for #Alzheimer disease @erzimmer.bsky.social
jama.com JAMA @jama.com · Aug 8
A recent study showed that newborns have high levels of p-tau, a biomarker for #Alzheimer disease.

Understanding how infants clear the protein could help prevent aggregation, which leads to #neurodegeneration in adults.

#MedSky #NeuroSky
Clues to Alzheimer Disease in the Newborn Brain
This Medical News article discusses a new finding that healthy infants have high blood levels of the protein p-tau217, a key biomarker for Alzheimer disease.
jamanetwork.com
August 9, 2025 at 6:01 PM
Reposted by Eduardo Zimmer
macauleylab.bsky.social
Tau pathology reprograms glucose metabolism to support glutamatergic activity and excitatory imbalance
biorxivpreprint.bsky.social bioRxivpreprint @biorxivpreprint.bsky.social · Jul 31
Tau pathology reprograms glucose metabolism to support glutamatergic activity and excitatory imbalance https://www.biorxiv.org/content/10.1101/2025.07.25.666872v1
July 31, 2025 at 4:42 PM
Reposted by Eduardo Zimmer
cgster.bsky.social
@beyoung40.bsky.social speaking about the @rushalzheimers.bsky.social Latino Core in Lima for the @alzassociation.bsky.social #AAICSatellite. Plus, she shouted out the team! @drmlamar.bsky.social and Dr. David Marquez

She’s so good!

@alzdemjournals.bsky.social
May 15, 2025 at 3:29 PM
Reposted by Eduardo Zimmer
zimmerneurolab.bsky.social
Dr. @erzimmer.bsky.social in action at the #AAICSatellite in Peru, presenting the landscape of 🩸biomarkers in Brazil. His talk highlighted key advances and outlined promising perspectives to boost Brazil’s response to dementia — from research to public health @alzassociation.bsky.social
May 14, 2025 at 4:18 PM
erzimmer.bsky.social
What a spectacular event the first @embo.org #Astrocyte Workshop was!
mdepitta.bsky.social Maurizio De Pittà @mdepitta.bsky.social · Apr 21
The first @embo.org #Astrocyte #Meeting was a success! Thanks to our excellent speakers, brilliant trainees, & DiBio @unipd.bsky.social volunteers. Looking forward to the next iteration! Laura.Civiero Matthew.Holt Olga.Sin WonSuk.Chun Keith.Murai Valentin.Nagerl @carmenfalcone.bsky.social
April 22, 2025 at 12:46 PM
erzimmer.bsky.social
An inspiring kickoff to the #EMBOastrocytes workshop honoring the legacy of #ElenaGalea
April 14, 2025 at 10:53 AM
Reposted by Eduardo Zimmer
carolynfredericks.bsky.social
We are HIRING!! Postdoc for multimodal imaging lab at Yale. If you get excited about preclinical and prodromal states, atypical Alzheimer’s, graph theory, predictive modeling, and/or baked goods at lab meetings, come join us: postdocs.yale.edu/postdoctoral...

Please share with your circles!
The Fredericks Lab! - with deliberately poor photoshopping of lab members who couldn't be there that day.
March 28, 2025 at 5:26 PM
Reposted by Eduardo Zimmer
neurosciencenext.bsky.social
Day 3 of Neuroscience
Next 2025 - Buenos Aires Hub 🇦🇷

#neuroscience #AAlCNeuroscienceNext #fleni #alzheimer
#alzheimersassociation #dementia
#neuropsychology #ENDALZ #argentina
#buenosaires #aging @erzimmer.bsky.social @luciacrivelli.bsky.social @alzassociation.bsky.social @nvillain-alz.bsky.social
March 1, 2025 at 10:39 AM
Reposted by Eduardo Zimmer
blacoste.bsky.social
I hope you haven’t missed this awesome new study by
@caromenard666.bsky.social’s team, where the dreamy keys worlds #astrocyte and #BloodBrainBarrier coexist 🤩🥰
Astrocytic cannabinoid receptor 1 promotes resilience by dampening stress-induced blood–brain barrier alterations - Nature Neuroscience
The mechanisms of neurovascular adaptations underlying stress resilience remain unclear. Here the authors show that the astrocytic endocannabinoid system modulates the blood–brain barrier changes duri...
www.nature.com
March 1, 2025 at 1:52 AM
Reposted by Eduardo Zimmer
caromenard666.bsky.social
So excited to share the work of the fantastic Katarzyna, 1st 🧪PhD student of my lab 🧠, out in @natureneuro.bsky.social 🥂🥳
Cheers to the team, thanks to our precious collaborators and support from @braincanada.bsky.social #CIHR @fondsrechercheqc.bsky.social #newPI

www.nature.com/articles/s41...
Astrocytic cannabinoid receptor 1 promotes resilience by dampening stress-induced blood–brain barrier alterations - Nature Neuroscience
The mechanisms of neurovascular adaptations underlying stress resilience remain unclear. Here the authors show that the astrocytic endocannabinoid system modulates the blood–brain barrier changes duri...
www.nature.com
February 27, 2025 at 11:52 AM
Reposted by Eduardo Zimmer
cgster.bsky.social
#AAICNeuro Cameroon Hub: Day Two!
February 26, 2025 at 9:18 AM
Reposted by Eduardo Zimmer
zimmerneurolab.bsky.social
Kickoff of #AAICNeuro in Porto Alegre! 🌎 This week, 12 hubs worldwide will showcase the next generation of Alzheimer’s & dementia researchers and clinicians.

Stay tuned for updates throughout the day!

@alzassociation.bsky.social @erzimmer.bsky.social #CristianoAguzzoli
February 24, 2025 at 1:14 PM
erzimmer.bsky.social
#AAICneuro POA Hub just started in our beloved Porto Alegre 🇧🇷! A great pleasure to co-host the event with #CristianoAguzzoli @zimmerneurolab.bsky.social @alzassociation.bsky.social
February 24, 2025 at 12:08 PM
erzimmer.bsky.social
Despite carrying a genetic mutation associated with early-onset #Alzheimer’s, a man remained free of dementia symptoms for at least 2 decades longer than expected 👉 genetic variants may explain this remarkable resilience. See more here: www.nature.com/articles/d41...
A man was destined for early Alzheimer’s — these genes might explain his escape
Scientists identify nine genetic variants that could have helped a man to avoid dementia for at least two decades longer than expected.
idp.nature.com
February 14, 2025 at 3:17 PM
erzimmer.bsky.social
Important work by #JorgeLibre-Guerra and team on @naturemedicine.bsky.social about genetic resilience to early onset #alzheimers👇

www.nature.com/articles/s41...
Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia - Nature Medicine
A rare case of asymptomatic dominantly inherited Alzheimer’s reveals confined tau pathology and unique proteomic features, highlighting potential resilience mechanisms decades beyond expected onset.
www.nature.com
February 14, 2025 at 3:13 PM
erzimmer.bsky.social
@stforner.bsky.social presenting the @alzassociation.bsky.social global funding programs at #FloripaNeuro 🇧🇷
February 10, 2025 at 7:12 PM
Reposted by Eduardo Zimmer
vbwyll.bsky.social
Incredibly happy to share this co-first publication in the Lancet Global Health with #DaRos and #Aguzzoli guided by the brilliant @erzimmer.bsky.social
February 8, 2025 at 3:46 PM
erzimmer.bsky.social
If you are a scientist in the Global South 👇👇👇👇
erzimmer.bsky.social Eduardo Zimmer @erzimmer.bsky.social · Nov 17
Starter pack to connect people from or working in science in the Global South!

👇👇👇👇👇

go.bsky.app/BDDMr9Y

If you’re not here yet, just let me know, and I’ll add you! Let’s connect! #sciencedemocratization 😊
February 7, 2025 at 3:16 PM
Reposted by Eduardo Zimmer
alzassociation.bsky.social
Hello, #Bluesky! With so many voices making their way to this new community, we are excited to enter the conversation.

#ENDALZ
The words "Hello, Bluesky!" with the Bluesky butterfly logo below. They are white against a purple background.
February 3, 2025 at 6:04 PM
Reposted by Eduardo Zimmer
istaart.bsky.social
The ISTAART Ambassador Program is still open for applications!

Hear what the current cohort has to say about the program, what it meant to them, and why you should apply!

www.youtube.com/watch?v=Y_7-...
The ISTAART Ambassador Program: Your Passport to a Global Dementia Research Community
YouTube video by Paige Logan
www.youtube.com
February 3, 2025 at 8:23 PM
Reposted by Eduardo Zimmer
cp-trendsneuro.bsky.social
'Origins of food selectivity in human visual cortex'

by Margaret Henderson, Michael Tarr & Leila Wehbe

www.cell.com/trends/neuro...
February 4, 2025 at 12:55 PM
erzimmer.bsky.social
In 🇧🇷, and probably in most countries with high levels of disparities and inequalities, education is one the most important risk factors for cognitive decline! Amazing work by #LucasdaRos @vbwyll.bsky.social #CristianoAguzzoli and team @thelancet.bsky.social
February 2, 2025 at 6:17 PM
Reposted by Eduardo Zimmer
baldassogabi.bsky.social
Check out our group's new study highlighting the importance of understanding the population in the Global South! 👇 Congrats #LucasdaRos @vbwyll.bsky.social @erzimmer.bsky.social
January 30, 2025 at 11:56 AM
Reposted by Eduardo Zimmer
zimmerneurolab.bsky.social
New Study just out in The Lancet Global Health! #LucasDaRos, @vbwyll.bsky.social, #CristianoAguzzoli & colleagues used a machine learning model to determine the most important risk factors for cognitive and functional decline in Brazil and other LATAM Countries 🧵 www.thelancet.com/journals/lan...
Social and health disparities associated with healthy brain ageing in Brazil and in other Latin American countries
Our findings indicate that Brazil converges with other Latin American countries to show that heterogeneous factors impacted more than demographic factors, but also showed a unique set of health factor...
www.thelancet.com
January 30, 2025 at 8:52 AM