Caroline Menard
@caromenard666.bsky.social
🇨🇦 Associate Professor 👩🔬, Research Chair on Neurobiology of Stress & Resilience, foodie, gamer & metalhead. Menard Lab is @CERVO_ULaval @universitelaval in Quebec City
🧠🐭🔬🧪
🧠🐭🔬🧪
Pinned
Astrocytic cannabinoid receptor 1 promotes resilience by dampening stress-induced blood–brain barrier alterations - Nature Neuroscience
The mechanisms of neurovascular adaptations underlying stress resilience remain unclear. Here the authors show that the astrocytic endocannabinoid system modulates the blood–brain barrier changes duri...
www.nature.com
So excited to share the work of the fantastic Katarzyna, 1st 🧪PhD student of my lab 🧠, out in @natureneuro.bsky.social 🥂🥳
Cheers to the team, thanks to our precious collaborators and support from @braincanada.bsky.social #CIHR @fondsrechercheqc.bsky.social #newPI
www.nature.com/articles/s41...
Cheers to the team, thanks to our precious collaborators and support from @braincanada.bsky.social #CIHR @fondsrechercheqc.bsky.social #newPI
www.nature.com/articles/s41...
Reposted by Caroline Menard
Share your research at the next Canadian Neuroscience Meeting May 18-21, 2026 in Montreal!
Calls for Parallel Symposia, Satellite Meetings, Poster Abstract and Travel & Professional Awards are now open - Don't miss these opportunities!
can-acn.org/meeting-2026/
Calls for Parallel Symposia, Satellite Meetings, Poster Abstract and Travel & Professional Awards are now open - Don't miss these opportunities!
can-acn.org/meeting-2026/
November 14, 2025 at 7:34 PM
Share your research at the next Canadian Neuroscience Meeting May 18-21, 2026 in Montreal!
Calls for Parallel Symposia, Satellite Meetings, Poster Abstract and Travel & Professional Awards are now open - Don't miss these opportunities!
can-acn.org/meeting-2026/
Calls for Parallel Symposia, Satellite Meetings, Poster Abstract and Travel & Professional Awards are now open - Don't miss these opportunities!
can-acn.org/meeting-2026/
Reposted by Caroline Menard
We are grieving our friend and brilliant colleague Natalia Duque-Wilckens. A creative scientist, artist, caring mentor, and force for change. Words can’t describe the impact she had on lives at UC Davis, MSU, NC State and beyond. I feel lucky to have known her and wish her time didn’t end so soon
November 13, 2025 at 6:58 PM
We are grieving our friend and brilliant colleague Natalia Duque-Wilckens. A creative scientist, artist, caring mentor, and force for change. Words can’t describe the impact she had on lives at UC Davis, MSU, NC State and beyond. I feel lucky to have known her and wish her time didn’t end so soon
Reposted by Caroline Menard
Excited to have my piece on perimenopause published @thetransmitter.bsky.social
"Perimenopause: An important—and understudied—transition for the brain"
We need more studies & better education -we need this to be mainstream- knowledge is power! #WomensHealth
www.thetransmitter.org/sex-hormones...
"Perimenopause: An important—and understudied—transition for the brain"
We need more studies & better education -we need this to be mainstream- knowledge is power! #WomensHealth
www.thetransmitter.org/sex-hormones...
Perimenopause: An understudied transition for the brain
We know little about the mechanisms underlying well-known perimenopause symptoms in the brain. More research—in animals and humans—is essential.
www.thetransmitter.org
November 12, 2025 at 8:14 AM
Excited to have my piece on perimenopause published @thetransmitter.bsky.social
"Perimenopause: An important—and understudied—transition for the brain"
We need more studies & better education -we need this to be mainstream- knowledge is power! #WomensHealth
www.thetransmitter.org/sex-hormones...
"Perimenopause: An important—and understudied—transition for the brain"
We need more studies & better education -we need this to be mainstream- knowledge is power! #WomensHealth
www.thetransmitter.org/sex-hormones...
Reposted by Caroline Menard
The brain neurovascular epigenome and its association with dementia. #cerebrovascular #epigenetics
The brain neurovascular epigenome and its association with dementia
Ziegler et al. reveal distinct genetic and epigenetic mechanisms underlying Alzheimer’s
disease and cerebral small vessel disease within neurovascular cells, identifying
immune-related AD risk and bro...
www.cell.com
November 12, 2025 at 10:42 AM
The brain neurovascular epigenome and its association with dementia. #cerebrovascular #epigenetics
Reposted by Caroline Menard
Stoked to see our study out in final form! Big kudos to @jonathanamichaels.bsky.social for driving this along for the past 5 years.
Thrilled that our paper is out today in Nature!
www.nature.com/articles/s4...
www.nature.com/articles/s4...
Sensory expectations shape neural population dynamics in motor circuits
Nature - Experiments with human volunteers and macaques show that expectations produced by probabilistic cueing of future sensory inputs shape motor circuit dynamics in order to increase the...
www.nature.com
October 29, 2025 at 4:47 PM
Stoked to see our study out in final form! Big kudos to @jonathanamichaels.bsky.social for driving this along for the past 5 years.
Came back from a fantastic 2-week family trip in London 🇬🇧 and Dublin 🇮🇪 yesterday 🤩
So many cool buildings, museums, history, but I have to admit that Stonehenge was my favorite along with the Guinness brewery 🍻 (and some baby Guinness in a rock bar to finish the trip 😉)
So many cool buildings, museums, history, but I have to admit that Stonehenge was my favorite along with the Guinness brewery 🍻 (and some baby Guinness in a rock bar to finish the trip 😉)
October 26, 2025 at 2:04 PM
Came back from a fantastic 2-week family trip in London 🇬🇧 and Dublin 🇮🇪 yesterday 🤩
So many cool buildings, museums, history, but I have to admit that Stonehenge was my favorite along with the Guinness brewery 🍻 (and some baby Guinness in a rock bar to finish the trip 😉)
So many cool buildings, museums, history, but I have to admit that Stonehenge was my favorite along with the Guinness brewery 🍻 (and some baby Guinness in a rock bar to finish the trip 😉)
Reposted by Caroline Menard
Just out in Nature! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory nature.com/articles/s41.... New astrocyte tools are openly available at Addgene: addgene.org/Jun_Nagai/. 1/8
October 15, 2025 at 4:11 PM
Just out in Nature! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory nature.com/articles/s41.... New astrocyte tools are openly available at Addgene: addgene.org/Jun_Nagai/. 1/8
Reposted by Caroline Menard
Want to be our colleague? We have a faculty position in microbial systems biology looking for candidates. Please share. www.rh.ulaval.ca/emplois-disp...
Tenure-Track Faculty Position in Omics Data Analysis in the Field of Microbial Systems Biology | Ressources humaines | Université Laval
www.rh.ulaval.ca
October 9, 2025 at 9:00 AM
Want to be our colleague? We have a faculty position in microbial systems biology looking for candidates. Please share. www.rh.ulaval.ca/emplois-disp...
October 5, 2025 at 11:01 PM
Reposted by Caroline Menard
I’m hiring at all levels and accepting graduate students through Psychology and the Graduate Program in Neuroscience. Reach out if you’re interested in joining a collaborative, fun, creative, and supportive team in beautiful Vancouver! 🏔️ ⛷️ 🏖️ 🌆
September 29, 2025 at 4:31 PM
I’m hiring at all levels and accepting graduate students through Psychology and the Graduate Program in Neuroscience. Reach out if you’re interested in joining a collaborative, fun, creative, and supportive team in beautiful Vancouver! 🏔️ ⛷️ 🏖️ 🌆
Reposted by Caroline Menard
Happy to share our new preprint on BBB mechanobiology on bioRxiv:
www.biorxiv.org/cgi/content/...
We describe an exciting new link between tight junctions and cell-matrix adhesions during BBB maturation and in epileptic BBB dysfunction.
www.biorxiv.org/cgi/content/...
We describe an exciting new link between tight junctions and cell-matrix adhesions during BBB maturation and in epileptic BBB dysfunction.
Endothelial tight junctions and cell-matrix adhesions reciprocally control blood-brain barrier integrity
Brain endothelial cells (ECs) rely on mechanical cues to provide a physical barrier that protects the brain. Yet how ECs integrate forces to establish and maintain the blood-brain barrier (BBB) remain...
www.biorxiv.org
September 12, 2025 at 10:43 AM
Happy to share our new preprint on BBB mechanobiology on bioRxiv:
www.biorxiv.org/cgi/content/...
We describe an exciting new link between tight junctions and cell-matrix adhesions during BBB maturation and in epileptic BBB dysfunction.
www.biorxiv.org/cgi/content/...
We describe an exciting new link between tight junctions and cell-matrix adhesions during BBB maturation and in epileptic BBB dysfunction.
Got the chance to chat with Michel "Away" Langevin, 🥁 drummer of the legendary metal band Voivoid 🤘 last night while waiting for our poutines! 🤩
September 12, 2025 at 11:00 AM
Got the chance to chat with Michel "Away" Langevin, 🥁 drummer of the legendary metal band Voivoid 🤘 last night while waiting for our poutines! 🤩
Hot 🌶️ peppers experiment: all from our garden, jalapenos, Hungarian wax, shishitos of various colors..
Is the color associated with heat level 🔥?
Is the color associated with heat level 🔥?
September 11, 2025 at 1:37 AM
Hot 🌶️ peppers experiment: all from our garden, jalapenos, Hungarian wax, shishitos of various colors..
Is the color associated with heat level 🔥?
Is the color associated with heat level 🔥?
Reposted by Caroline Menard
Come join us at University of Toronto. We're hiring a Professor of computational cognitive neuroscience.
#neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...
#neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...
Professor - Computational Cognitive Neuroscience
Professor - Computational Cognitive Neuroscience
jobs.utoronto.ca
September 5, 2025 at 8:22 AM
Come join us at University of Toronto. We're hiring a Professor of computational cognitive neuroscience.
#neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...
#neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...
Reposted by Caroline Menard
Mood after the CIHR grant marathon.
September 10, 2025 at 12:15 AM
Mood after the CIHR grant marathon.
Reposted by Caroline Menard
JOB ALERT FOR #SOCIOLOGIST: Come work with me. We have FOUR Assistant Professor positions in the Sociology Department at the University of Calgary.
careers.ucalgary.ca/jobs/1672106...
careers.ucalgary.ca/jobs/1672106...
Assistant Professors - Sociology, Faculty of Arts in
Calgary,
AB,
...
Assistant Professors - Sociology, Faculty of Arts in
Calgary,
AB,
...
careers.ucalgary.ca
September 10, 2025 at 12:35 AM
JOB ALERT FOR #SOCIOLOGIST: Come work with me. We have FOUR Assistant Professor positions in the Sociology Department at the University of Calgary.
careers.ucalgary.ca/jobs/1672106...
careers.ucalgary.ca/jobs/1672106...
Reposted by Caroline Menard
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.
www.nature.com/naturecareer...
Please repost!
www.nature.com/naturecareer...
Please repost!
August 28, 2025 at 6:34 AM
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.
www.nature.com/naturecareer...
Please repost!
www.nature.com/naturecareer...
Please repost!
Reposted by Caroline Menard
🚨Another PI job opening in the Neuroscience dept. at @umontreal.ca ! 🚨
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Professor at the rank of Assistant or Associate Professor, in the field of neurocircuitry - Montréal, Quebec (CA) job with Université de Montréal | 12843808
Professor at the rank of Assistant or Associate Professor, in the field of neurocircuitry involved in the production of complex behaviors
www.nature.com
August 21, 2025 at 11:57 PM
🚨Another PI job opening in the Neuroscience dept. at @umontreal.ca ! 🚨
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Reposted by Caroline Menard
For anyone interested in an academic job in 🇨🇦, we will soon be advertising an Assistant Prof position in Systems Neuroscience (rodents and other animal models) at ULethbridge. There are many pros and cons of working here, so feel free to DM me to find out more
#neuroskyence #academicsky
#neuroskyence #academicsky
August 20, 2025 at 2:26 AM
For anyone interested in an academic job in 🇨🇦, we will soon be advertising an Assistant Prof position in Systems Neuroscience (rodents and other animal models) at ULethbridge. There are many pros and cons of working here, so feel free to DM me to find out more
#neuroskyence #academicsky
#neuroskyence #academicsky
Reposted by Caroline Menard
Happy to announce our new paper in Nature Communications: rdcu.be/eBpGY
We show how CRH in the thalamic reticular nucleus modulates NREM sleep, helping to understand how stress impacts sleep
Congrats to Loredana Cumpana and team, in work led by Simone Astori!
@epfl-brainmind.bsky.social
We show how CRH in the thalamic reticular nucleus modulates NREM sleep, helping to understand how stress impacts sleep
Congrats to Loredana Cumpana and team, in work led by Simone Astori!
@epfl-brainmind.bsky.social
Corticotropin-releasing hormone modulates NREM sleep consolidation through the thalamic reticular nucleus
Nature Communications - Corticotropin-releasing hormone (CRH), known for activating the HPA axis during stress, also acts centrally in the brain. Here, the authors show that CRH modulates thalamic...
rdcu.be
August 20, 2025 at 7:16 AM
Happy to announce our new paper in Nature Communications: rdcu.be/eBpGY
We show how CRH in the thalamic reticular nucleus modulates NREM sleep, helping to understand how stress impacts sleep
Congrats to Loredana Cumpana and team, in work led by Simone Astori!
@epfl-brainmind.bsky.social
We show how CRH in the thalamic reticular nucleus modulates NREM sleep, helping to understand how stress impacts sleep
Congrats to Loredana Cumpana and team, in work led by Simone Astori!
@epfl-brainmind.bsky.social
Reposted by Caroline Menard
Thrilled to share our new study showing microglia prune astrocyte processes in adult brain, to regulate synaptic transmission, hypothalamic neuron activity, and salt-induced hypertension in🐀. Huge team effort - congratulations to all🥂🍾🎉
August 19, 2025 at 4:26 PM
Thrilled to share our new study showing microglia prune astrocyte processes in adult brain, to regulate synaptic transmission, hypothalamic neuron activity, and salt-induced hypertension in🐀. Huge team effort - congratulations to all🥂🍾🎉
Reposted by Caroline Menard
I am SO EXCITED to share this one! The latest paper from the lab is online in @cp-cellreports.bsky.social. We show microglia prune NAc astrocyte processes during abstinence from cocaine-self ad which drives later drug seeking behavior.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Abstinence from cocaine self-administration promotes microglial pruning of astrocytes, which drives cocaine-seeking behavior
Rodent drug self-administration leads to a compromised ability of nucleus accumbens astrocytes to maintain glutamate homeostasis as well as to reducti…
www.sciencedirect.com
August 13, 2025 at 6:48 PM
I am SO EXCITED to share this one! The latest paper from the lab is online in @cp-cellreports.bsky.social. We show microglia prune NAc astrocyte processes during abstinence from cocaine-self ad which drives later drug seeking behavior.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Caroline Menard
Excellent paper from @emreyaksi.bsky.social @manumameli.bsky.social labs. So much gold in the supplementary figures!
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Calcium dynamics in habenular astrocytes regulate active coping within behavioral transitions - Communications Biology
Tracking of astrocytes dynamics in habenula reveals their contribution to behavioral transitions across species.
www.nature.com
August 8, 2025 at 2:43 PM
Excellent paper from @emreyaksi.bsky.social @manumameli.bsky.social labs. So much gold in the supplementary figures!
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by Caroline Menard
Review now out in @npp-journal.bsky.social!
Epigenetic regulation of brain development, plasticity, and response to early life stress
rdcu.be/ezzYq
Epigenetic regulation of brain development, plasticity, and response to early life stress
rdcu.be/ezzYq
Epigenetic regulation of brain development, plasticity, and response to early-life stress
Neuropsychopharmacology - Epigenetic regulation of brain development, plasticity, and response to early-life stress
rdcu.be
August 6, 2025 at 3:38 PM
Review now out in @npp-journal.bsky.social!
Epigenetic regulation of brain development, plasticity, and response to early life stress
rdcu.be/ezzYq
Epigenetic regulation of brain development, plasticity, and response to early life stress
rdcu.be/ezzYq
Reposted by Caroline Menard
So happy to see this excellent work out!
‘Gut microbiota regulates exercise-induced hormetic modulation of cognitive function’
Fantastic collaboration with @jltrejoneuro.bsky.social @cintadoelisa.bsky.social @jfcryan.bsky.social
www.thelancet.com/journals/ebi...
‘Gut microbiota regulates exercise-induced hormetic modulation of cognitive function’
Fantastic collaboration with @jltrejoneuro.bsky.social @cintadoelisa.bsky.social @jfcryan.bsky.social
www.thelancet.com/journals/ebi...
Gut microbiota regulates exercise-induced hormetic modulation of cognitive function
These findings suggest that the hormetic effects of physical exercise on cognitive
function and neurogenesis are mediated by corresponding changes in the gut microbiota,
highlighting a novel mechanist...
www.thelancet.com
August 6, 2025 at 10:03 AM
So happy to see this excellent work out!
‘Gut microbiota regulates exercise-induced hormetic modulation of cognitive function’
Fantastic collaboration with @jltrejoneuro.bsky.social @cintadoelisa.bsky.social @jfcryan.bsky.social
www.thelancet.com/journals/ebi...
‘Gut microbiota regulates exercise-induced hormetic modulation of cognitive function’
Fantastic collaboration with @jltrejoneuro.bsky.social @cintadoelisa.bsky.social @jfcryan.bsky.social
www.thelancet.com/journals/ebi...