Gergo Porkolab
@gergoporkolab.bsky.social
Research Fellow at the Campbell Lab @tcddublin.bsky.social
studying signaling pathways that regulate blood vessels in the brain
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Previously @BarriersGroup, Szeged, Hungary
studying signaling pathways that regulate blood vessels in the brain
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Previously @BarriersGroup, Szeged, Hungary
Happy to share our new preprint on BBB mechanobiology on bioRxiv:
www.biorxiv.org/cgi/content/...
We describe an exciting new link between tight junctions and cell-matrix adhesions during BBB maturation and in epileptic BBB dysfunction.
www.biorxiv.org/cgi/content/...
We describe an exciting new link between tight junctions and cell-matrix adhesions during BBB maturation and in epileptic BBB dysfunction.
Endothelial tight junctions and cell-matrix adhesions reciprocally control blood-brain barrier integrity
Brain endothelial cells (ECs) rely on mechanical cues to provide a physical barrier that protects the brain. Yet how ECs integrate forces to establish and maintain the blood-brain barrier (BBB) remain...
www.biorxiv.org
September 12, 2025 at 10:43 AM
Happy to share our new preprint on BBB mechanobiology on bioRxiv:
www.biorxiv.org/cgi/content/...
We describe an exciting new link between tight junctions and cell-matrix adhesions during BBB maturation and in epileptic BBB dysfunction.
www.biorxiv.org/cgi/content/...
We describe an exciting new link between tight junctions and cell-matrix adhesions during BBB maturation and in epileptic BBB dysfunction.
Reposted by Gergo Porkolab
New paper led by Avril Reddy in @mattcampbelltcd.bsky.social lab showing IPS derived human RPE cells expressing aflibercept and/or soluble CD59 can attenuate lesions in mouse model of age-related macular degeneration. Cool project to help out with. www.cell.com/molecular-th...
Enhanced retinal pigment epithelial cells as a delivery vehicle for retinal disease
Age-related macular degeneration (AMD) is one of the leading causes of central retinal
blindness. Here, Campbell and colleagues show that transplanted retinal pigment epithelial
cells can be engineere...
www.cell.com
March 19, 2025 at 11:41 AM
New paper led by Avril Reddy in @mattcampbelltcd.bsky.social lab showing IPS derived human RPE cells expressing aflibercept and/or soluble CD59 can attenuate lesions in mouse model of age-related macular degeneration. Cool project to help out with. www.cell.com/molecular-th...