Zimmer Lab
@zimmerneurolab.bsky.social
Multidisciplinary lab, at @ufrgs.br, interested in understanding neuron-to-astrocyte communication in neurodegenerative disorders linktr.ee/zimmerneurolab
Just published in Nat. Neurosci.
Led by J.P. Ferrari-Souza, this study used imaging & fluid biomarkers to reveal that microglia modulate Aβ-related astrocyte reactivity, which in turn contributes to AD progression.
@erzimmer.bsky.social
@natureportfolio.nature.com
www.nature.com/articles/s41...
Led by J.P. Ferrari-Souza, this study used imaging & fluid biomarkers to reveal that microglia modulate Aβ-related astrocyte reactivity, which in turn contributes to AD progression.
@erzimmer.bsky.social
@natureportfolio.nature.com
www.nature.com/articles/s41...
Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer’s disease - Nature Neuroscience
Microglia influence amyloid-β effects on astrocyte reactivity in the living brain of individuals with Alzheimer’s disease. This phenomenon further contributes to cognitive impairment via tau phosphory...
www.nature.com
November 7, 2025 at 10:16 AM
Just published in Nat. Neurosci.
Led by J.P. Ferrari-Souza, this study used imaging & fluid biomarkers to reveal that microglia modulate Aβ-related astrocyte reactivity, which in turn contributes to AD progression.
@erzimmer.bsky.social
@natureportfolio.nature.com
www.nature.com/articles/s41...
Led by J.P. Ferrari-Souza, this study used imaging & fluid biomarkers to reveal that microglia modulate Aβ-related astrocyte reactivity, which in turn contributes to AD progression.
@erzimmer.bsky.social
@natureportfolio.nature.com
www.nature.com/articles/s41...
📣 Last call!
@istaart.bsky.social members — submit your abstract for AAIC Neuroscience Next, the hybrid event happening in 6 cities worldwide 🌍🧠
📅 Deadline: this Sunday!
Don’t miss your chance to share your research globally.
🔗 tinyurl.com/mpe85jfd
@erzimmer.bsky.social @ozyismail.bsky.social
@istaart.bsky.social members — submit your abstract for AAIC Neuroscience Next, the hybrid event happening in 6 cities worldwide 🌍🧠
📅 Deadline: this Sunday!
Don’t miss your chance to share your research globally.
🔗 tinyurl.com/mpe85jfd
@erzimmer.bsky.social @ozyismail.bsky.social
October 25, 2025 at 11:53 AM
📣 Last call!
@istaart.bsky.social members — submit your abstract for AAIC Neuroscience Next, the hybrid event happening in 6 cities worldwide 🌍🧠
📅 Deadline: this Sunday!
Don’t miss your chance to share your research globally.
🔗 tinyurl.com/mpe85jfd
@erzimmer.bsky.social @ozyismail.bsky.social
@istaart.bsky.social members — submit your abstract for AAIC Neuroscience Next, the hybrid event happening in 6 cities worldwide 🌍🧠
📅 Deadline: this Sunday!
Don’t miss your chance to share your research globally.
🔗 tinyurl.com/mpe85jfd
@erzimmer.bsky.social @ozyismail.bsky.social
✈️ Toronto, here we go! The ZLAB team is heading to #AAIC2025, the world’s largest conference on AD and dementia. 5 days of science, learning and a chance to showcase research made in Brazil🧠
Check out all our presentations here: tinyurl.com/533zfkhs
@alzassociation.bsky.social
Check out all our presentations here: tinyurl.com/533zfkhs
@alzassociation.bsky.social
July 20, 2025 at 1:28 PM
✈️ Toronto, here we go! The ZLAB team is heading to #AAIC2025, the world’s largest conference on AD and dementia. 5 days of science, learning and a chance to showcase research made in Brazil🧠
Check out all our presentations here: tinyurl.com/533zfkhs
@alzassociation.bsky.social
Check out all our presentations here: tinyurl.com/533zfkhs
@alzassociation.bsky.social
Congrats to PhD student @limberger-chris.bsky.social on his Lightning Presentation at #AAICSatellite in Lima!
🧠His talk: "Brain Hypometabolism and Cognitive Impairment Are Exacerbated by a Common IDO1 Genetic Variant" was excellent! 👏 @alzassociation.bsky.social
🧠His talk: "Brain Hypometabolism and Cognitive Impairment Are Exacerbated by a Common IDO1 Genetic Variant" was excellent! 👏 @alzassociation.bsky.social
May 15, 2025 at 4:39 PM
Congrats to PhD student @limberger-chris.bsky.social on his Lightning Presentation at #AAICSatellite in Lima!
🧠His talk: "Brain Hypometabolism and Cognitive Impairment Are Exacerbated by a Common IDO1 Genetic Variant" was excellent! 👏 @alzassociation.bsky.social
🧠His talk: "Brain Hypometabolism and Cognitive Impairment Are Exacerbated by a Common IDO1 Genetic Variant" was excellent! 👏 @alzassociation.bsky.social
Dr. @erzimmer.bsky.social in action at the #AAICSatellite in Peru, presenting the landscape of 🩸biomarkers in Brazil. His talk highlighted key advances and outlined promising perspectives to boost Brazil’s response to dementia — from research to public health @alzassociation.bsky.social
May 14, 2025 at 4:18 PM
Dr. @erzimmer.bsky.social in action at the #AAICSatellite in Peru, presenting the landscape of 🩸biomarkers in Brazil. His talk highlighted key advances and outlined promising perspectives to boost Brazil’s response to dementia — from research to public health @alzassociation.bsky.social
Reposted by Zimmer Lab
Aluna da UFRGS é reconhecida como mais promissora pesquisadora do mundo. Giovanna Carello Collar recebeu o prêmio "One to Watch", na Conferência Internacional da Associação de Alzheimer.
tinyurl.com/47b8seks
tinyurl.com/47b8seks
March 14, 2025 at 3:36 PM
Aluna da UFRGS é reconhecida como mais promissora pesquisadora do mundo. Giovanna Carello Collar recebeu o prêmio "One to Watch", na Conferência Internacional da Associação de Alzheimer.
tinyurl.com/47b8seks
tinyurl.com/47b8seks
If you're in Miami for #AAICAdvancements, don’t miss the poster session featuring our undergrad student #MariaLuizaDahlem! 🧠✨ Monday morning—see you there! @alzassociation.bsky.social
March 14, 2025 at 11:40 AM
If you're in Miami for #AAICAdvancements, don’t miss the poster session featuring our undergrad student #MariaLuizaDahlem! 🧠✨ Monday morning—see you there! @alzassociation.bsky.social
Yesterday, we had the honor of hosting Dr. @mateferretti.bsky.social for a special lab meeting in a packed auditorium. Her visit to Porto Alegre brought invaluable insights and inspiring discussions.
We are grateful for her time, expertise, and passion.
Thank you for inspiring us all!
We are grateful for her time, expertise, and passion.
Thank you for inspiring us all!
March 14, 2025 at 11:14 AM
Yesterday, we had the honor of hosting Dr. @mateferretti.bsky.social for a special lab meeting in a packed auditorium. Her visit to Porto Alegre brought invaluable insights and inspiring discussions.
We are grateful for her time, expertise, and passion.
Thank you for inspiring us all!
We are grateful for her time, expertise, and passion.
Thank you for inspiring us all!
🎉 Congratulations to our PhD student @giovannacollar.bsky.social for receiving the AAIC Neuroscience Next ‘One to Watch’ Award at #AAICNeuro 🇺🇸!
A well-deserved recognition by the @alzassociation.bsky.social for her contributions to neuroscience research. 👏✨
A well-deserved recognition by the @alzassociation.bsky.social for her contributions to neuroscience research. 👏✨
February 27, 2025 at 9:17 PM
🎉 Congratulations to our PhD student @giovannacollar.bsky.social for receiving the AAIC Neuroscience Next ‘One to Watch’ Award at #AAICNeuro 🇺🇸!
A well-deserved recognition by the @alzassociation.bsky.social for her contributions to neuroscience research. 👏✨
A well-deserved recognition by the @alzassociation.bsky.social for her contributions to neuroscience research. 👏✨
Kickoff of #AAICNeuro in Porto Alegre! 🌎 This week, 12 hubs worldwide will showcase the next generation of Alzheimer’s & dementia researchers and clinicians.
Stay tuned for updates throughout the day!
@alzassociation.bsky.social @erzimmer.bsky.social #CristianoAguzzoli
Stay tuned for updates throughout the day!
@alzassociation.bsky.social @erzimmer.bsky.social #CristianoAguzzoli
February 24, 2025 at 1:14 PM
Kickoff of #AAICNeuro in Porto Alegre! 🌎 This week, 12 hubs worldwide will showcase the next generation of Alzheimer’s & dementia researchers and clinicians.
Stay tuned for updates throughout the day!
@alzassociation.bsky.social @erzimmer.bsky.social #CristianoAguzzoli
Stay tuned for updates throughout the day!
@alzassociation.bsky.social @erzimmer.bsky.social #CristianoAguzzoli
#AAICNeuro starts next week! In 2025, 12 hubs will offer lectures, poster presentations, networking sessions, and workshops. @alzassociation.bsky.social
Click the link to see our participation at 5 of these hubs!
tinyurl.com/3th28xfd
Click the link to see our participation at 5 of these hubs!
tinyurl.com/3th28xfd
February 20, 2025 at 12:00 PM
#AAICNeuro starts next week! In 2025, 12 hubs will offer lectures, poster presentations, networking sessions, and workshops. @alzassociation.bsky.social
Click the link to see our participation at 5 of these hubs!
tinyurl.com/3th28xfd
Click the link to see our participation at 5 of these hubs!
tinyurl.com/3th28xfd
Reposted by Zimmer Lab
Despite carrying a genetic mutation associated with early-onset #Alzheimer’s, a man remained free of dementia symptoms for at least 2 decades longer than expected 👉 genetic variants may explain this remarkable resilience. See more here: www.nature.com/articles/d41...
A man was destined for early Alzheimer’s — these genes might explain his escape
Scientists identify nine genetic variants that could have helped a man to avoid dementia for at least two decades longer than expected.
idp.nature.com
February 14, 2025 at 3:17 PM
Despite carrying a genetic mutation associated with early-onset #Alzheimer’s, a man remained free of dementia symptoms for at least 2 decades longer than expected 👉 genetic variants may explain this remarkable resilience. See more here: www.nature.com/articles/d41...
New Study just out in The Lancet Global Health! #LucasDaRos, @vbwyll.bsky.social, #CristianoAguzzoli & colleagues used a machine learning model to determine the most important risk factors for cognitive and functional decline in Brazil and other LATAM Countries 🧵 www.thelancet.com/journals/lan...
Social and health disparities associated with healthy brain ageing in Brazil and in other Latin American countries
Our findings indicate that Brazil converges with other Latin American countries to
show that heterogeneous factors impacted more than demographic factors, but also showed
a unique set of health factor...
www.thelancet.com
January 30, 2025 at 8:52 AM
New Study just out in The Lancet Global Health! #LucasDaRos, @vbwyll.bsky.social, #CristianoAguzzoli & colleagues used a machine learning model to determine the most important risk factors for cognitive and functional decline in Brazil and other LATAM Countries 🧵 www.thelancet.com/journals/lan...
Valuing diversity and mutual learning: two researchers from Nigeria have joined our team, further enriching our international collaborations and expanding horizons in the laboratory. #science #diversity
January 22, 2025 at 7:42 PM
Valuing diversity and mutual learning: two researchers from Nigeria have joined our team, further enriching our international collaborations and expanding horizons in the laboratory. #science #diversity
Reposted by Zimmer Lab
This international event aims to support and showcase the next generation of researchers and clinicians, providing a plataform for knowledge exchange
Be part of what's next in neuroscience
⚠️ Limited spots available
📝 Free registration
#neuroscience #neurobiology #neuropsychology #psychology #aaic
Be part of what's next in neuroscience
⚠️ Limited spots available
📝 Free registration
#neuroscience #neurobiology #neuropsychology #psychology #aaic
January 7, 2025 at 8:44 PM
This international event aims to support and showcase the next generation of researchers and clinicians, providing a plataform for knowledge exchange
Be part of what's next in neuroscience
⚠️ Limited spots available
📝 Free registration
#neuroscience #neurobiology #neuropsychology #psychology #aaic
Be part of what's next in neuroscience
⚠️ Limited spots available
📝 Free registration
#neuroscience #neurobiology #neuropsychology #psychology #aaic
Reposted by Zimmer Lab
💡It’s out! Our Spotlight published in TINS on the combination of BOLD-fMRI, FDG-fPET, and optogenetics stimulation by Haas, Bravo, and coleagues!
👉 This innovative combination of in vivo imaging techniques holds great potential for addressing fundamental questions in neuroscience.
👉 This innovative combination of in vivo imaging techniques holds great potential for addressing fundamental questions in neuroscience.
‘Assessing brain-wide outcomes of dopamine system activation in the living rodent brain’
TINS ‘Spotlight’ by @limberger-chris.bsky.social & @erzimmer.bsky.social
www.cell.com/trends/neuro...
discussing Haas, Bravo, et al., 2024, Kristina Herfert group
www.science.org/doi/10.1126/...
TINS ‘Spotlight’ by @limberger-chris.bsky.social & @erzimmer.bsky.social
www.cell.com/trends/neuro...
discussing Haas, Bravo, et al., 2024, Kristina Herfert group
www.science.org/doi/10.1126/...
Assessing brain-wide outcomes of dopamine system activation in the living rodent brain
In a recent study, Haas, Bravo, and colleagues integrated optogenetic stimulation with simultaneous functional in vivo positron emission tomography (PET)/magnetic resonance imaging (MRI) measurements in rats. By activating the nigrostriatal pathway in the substantia nigra pars compacta (SNc), they observed concurrent metabolic and hemodynamic fluctuations associated with the dopaminergic pathway in living animals at the whole-brain level.
www.cell.com
January 6, 2025 at 4:48 PM
💡It’s out! Our Spotlight published in TINS on the combination of BOLD-fMRI, FDG-fPET, and optogenetics stimulation by Haas, Bravo, and coleagues!
👉 This innovative combination of in vivo imaging techniques holds great potential for addressing fundamental questions in neuroscience.
👉 This innovative combination of in vivo imaging techniques holds great potential for addressing fundamental questions in neuroscience.
Reposted by Zimmer Lab
Meet our #NeuroSpeaker Dr. Eduardo Zimmer!
He will be part of Buenos Aires Hub 2025 to speak about “The cellular Origins of Neurodegeneration”
Dont miss his presentation!
📎 bit.ly/NeuroscienceNext2025_Registration
#neuroscience #aaic #alzheimersassociation #neurodegeneration #endalz #argentina
He will be part of Buenos Aires Hub 2025 to speak about “The cellular Origins of Neurodegeneration”
Dont miss his presentation!
📎 bit.ly/NeuroscienceNext2025_Registration
#neuroscience #aaic #alzheimersassociation #neurodegeneration #endalz #argentina
January 3, 2025 at 5:14 PM
Meet our #NeuroSpeaker Dr. Eduardo Zimmer!
He will be part of Buenos Aires Hub 2025 to speak about “The cellular Origins of Neurodegeneration”
Dont miss his presentation!
📎 bit.ly/NeuroscienceNext2025_Registration
#neuroscience #aaic #alzheimersassociation #neurodegeneration #endalz #argentina
He will be part of Buenos Aires Hub 2025 to speak about “The cellular Origins of Neurodegeneration”
Dont miss his presentation!
📎 bit.ly/NeuroscienceNext2025_Registration
#neuroscience #aaic #alzheimersassociation #neurodegeneration #endalz #argentina
Reposted by Zimmer Lab
Exciting news this Christmas: our spotlight, led by @limberger-chris.bsky.social, on Haas, Bravo et al. 2024 is out now in @cp-trendsneuro.bsky.social 👉 www.sciencedirect.com/science/arti... @zimmerneurolab.bsky.social
Assessing brain-wide outcomes of dopamine system activation in the living rodent brain
In a recent study, Haas, Bravo, and colleagues integrated optogenetic stimulation with simultaneous functional in vivo positron emission tomography (P…
www.sciencedirect.com
December 24, 2024 at 3:10 PM
Exciting news this Christmas: our spotlight, led by @limberger-chris.bsky.social, on Haas, Bravo et al. 2024 is out now in @cp-trendsneuro.bsky.social 👉 www.sciencedirect.com/science/arti... @zimmerneurolab.bsky.social
The Zimmer Lab wishes everyone a joyful holiday season and a successful 2025! 🎄🥂
We are grateful for the partnerships and inspiring moments shared in 2024. Here’s to a new year filled with discoveries, collaborations, and achievements. ✨🎉
We are grateful for the partnerships and inspiring moments shared in 2024. Here’s to a new year filled with discoveries, collaborations, and achievements. ✨🎉
December 24, 2024 at 10:48 AM
The Zimmer Lab wishes everyone a joyful holiday season and a successful 2025! 🎄🥂
We are grateful for the partnerships and inspiring moments shared in 2024. Here’s to a new year filled with discoveries, collaborations, and achievements. ✨🎉
We are grateful for the partnerships and inspiring moments shared in 2024. Here’s to a new year filled with discoveries, collaborations, and achievements. ✨🎉
Happy Birthday, @erzimmer.bsky.social! 🎉
Thank you for your mentorship, for being such an inspiration, and for making a meaningful impact on our lives every single day. 🎂🎈
Thank you for your mentorship, for being such an inspiration, and for making a meaningful impact on our lives every single day. 🎂🎈
December 7, 2024 at 11:26 AM
Happy Birthday, @erzimmer.bsky.social! 🎉
Thank you for your mentorship, for being such an inspiration, and for making a meaningful impact on our lives every single day. 🎂🎈
Thank you for your mentorship, for being such an inspiration, and for making a meaningful impact on our lives every single day. 🎂🎈
Reposted by Zimmer Lab
Time to embrace astrocyte heterogeneity! @zimmerneurolab.bsky.social
www.alzforum.org/news/researc... 👇
www.alzforum.org/news/researc... 👇
December 5, 2024 at 11:27 PM
Time to embrace astrocyte heterogeneity! @zimmerneurolab.bsky.social
www.alzforum.org/news/researc... 👇
www.alzforum.org/news/researc... 👇
Reposted by Zimmer Lab
Today marked the final day of my one-month visit to Pedro Rosa-Neto’s lab at @theneuro.bsky.social. This experience was a remarkable milestone in my PhD journey. I’m definitely returning to Brazil filled with knowledge and happiness!
Thank you all for this unique opportunity! 😊
Thank you all for this unique opportunity! 😊
November 30, 2024 at 1:57 AM
Today marked the final day of my one-month visit to Pedro Rosa-Neto’s lab at @theneuro.bsky.social. This experience was a remarkable milestone in my PhD journey. I’m definitely returning to Brazil filled with knowledge and happiness!
Thank you all for this unique opportunity! 😊
Thank you all for this unique opportunity! 😊
📄 In a new study just published in the Journal of Nuclear Medicine, our PhD student #AntonioAliaga, in collaboration with #Prof.PedroRosa-Neto's team, evaluated the binding properties of tau radiotracers in postmortem human brain tissue in the context of AD. 👇 1/n jnm.snmjournals.org/content/earl...
Comparison Between Brain and Cerebellar Autoradiography Using [18F]Flortaucipir, [18F]MK6240, and [18F]PI2620 in Postmortem Human Brain Tissue
Our objective was to evaluate the in vitro binding properties of [18F]flortaucipir, 6-(fluoro-18F)-3-(1 H -pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([18F]MK6240), and 2-(2-([18F]fluoro)pyridin-4...
jnm.snmjournals.org
November 25, 2024 at 6:25 PM
📄 In a new study just published in the Journal of Nuclear Medicine, our PhD student #AntonioAliaga, in collaboration with #Prof.PedroRosa-Neto's team, evaluated the binding properties of tau radiotracers in postmortem human brain tissue in the context of AD. 👇 1/n jnm.snmjournals.org/content/earl...