Emily Madden
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emadden.bsky.social
Emily Madden
@emadden.bsky.social
I work with scientists to make cool tech for epigenomics and chromatin biology research.
📍STL
Reposted by Emily Madden
Psyched to say that Mike Diamond is talking at our next seminar. THURSDAY 20th Nov. All welcome!
World leading #virology not to be missed - just email us for a Zoom link.
Please help us with a re-post to get the word out 👍
November 13, 2025 at 10:28 AM
Reposted by Emily Madden
I’d love to create a mini series highlighting the cool biology folks uncover with the help of this kit.

If you use this kit, please get in touch so I can highlight YOU and YOUR WORK!
November 12, 2025 at 3:41 AM
I’m proud of the team that made this launch possible and incredibly appreciative of Dr. Stergachis for trusting us to turn his tech into a reliable commercial product.

But what I’m REALLY excited for is seeing the cool data folks generate using this kit.
Fiber-seq is your complete solution for profiling chromatin accessibility, DNA methylation, and protein footprints in ONE multiomic experiment. This kit contains everything you need to get this assay up and running in your lab.

🔗 Try CUTANA™ Fiber-seq: https://www.epicypher.com/products/fiber-seq/
November 12, 2025 at 3:41 AM
Sunday morning time cleanse:

A picture of the goodest boy who was so well behaved on his morning adventure to Lowe’s.
November 9, 2025 at 3:43 PM
Reposted by Emily Madden
We are delighted that @genesdev.bsky.social have selected our (w/ @adrianbracken.bsky.social) Weaver syndrome paper artwork as the November cover! This piece was made by my incredibly talented niece, Gina 'Dna Vinci' Ronan.

@ucddublin.bsky.social @tcddublin.bsky.social @ucd-sbbs.bsky.social
🚨 NEW ISSUE ALERT!!! 🚨

New Outlook, Review and Research articles online now at Genes & Development.

Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/21-22.toc
November 3, 2025 at 6:18 PM
Reposted by Emily Madden
someone invited people magazine to the kitchen and they brought their own knives
November 2, 2025 at 6:00 PM
Reposted by Emily Madden
Dr. Steven Henikoff receives the 55th Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research.
www.brandeis.edu/rosenstiel/r...

(Personal note: I continue to be inspired and astonished by my postdoctoral mentor & current colleague)
Brandeis University honors Fred Hutch molecular biologist
Dr. Steven Henikoff, a molecular biologist at Fred Hutch Cancer Center, has won the prestigious Rosenstiel Award for Distinguished Work in Basic Medical Research from Brandeis University recognizing h...
www.fredhutch.org
October 31, 2025 at 12:48 AM
A colleague showed up to the work costume contest dressed as Fiber-seq. No notes. She got my vote.
October 30, 2025 at 8:34 PM
Reposted by Emily Madden
Hi Genome Engineering peeps!

When you genotype crude cell lysates after colony picking, which PCR enzyme/buffer composition works best for you for genotyping >1.5kb amplicons?

KOD Xtreme is amazingly robust but so $$$😬

Thank you!
October 28, 2025 at 5:23 PM
Reposted by Emily Madden
If I were running the DNC, there would be Democratic Party sponsored food relief banks across the country right now that specifically welcomed anyone regardless of party affiliation.

Along with the food, there could be voter registration and links to runforsomething.net
October 26, 2025 at 9:03 PM
Checked in on some new friends this weekend while the human friends were out of town.
October 26, 2025 at 10:46 PM
Them: But you’re so outgoing, don’t you get lonely working from home?

Me: Not really.
October 22, 2025 at 7:28 PM
Reposted by Emily Madden
reposting with alt text bc i love this
October 18, 2025 at 9:10 PM
Reposted by Emily Madden
WOW! Protesters created a HUGE human sign on San Francisco’s Ocean Beach reading “No Kings YES on 50” to support California’s Prop 50 and stand up against Donald Trump’s fascist regime
October 18, 2025 at 7:53 PM
Reposted by Emily Madden
Nye: We are here to tell our lawmakers that what's going on in our government is
wrong. They must stop the abuses of this petulant president and his circle of sycophants. No thrones, no crowns, no king
October 18, 2025 at 5:01 PM
Swung by Boston Common on my way out today. Bummed I didn’t get my flight moved so I could have stuck around.
October 18, 2025 at 5:59 PM
It’s not that surprising but @plasmidsaurus.bsky.social had the best swag at #ASHG25 this year. Followed closely behind the Parse yeti mug (which I was not fortunate enough to get).
October 18, 2025 at 3:21 AM
Reposted by Emily Madden
We have a bunch of new job ads out @arcadiascience.com. If you haven’t checked them out, take a look!

www.arcadiascience.com/careers
Careers | Arcadia Science
Evolve with Arcadia.
www.arcadiascience.com
October 16, 2025 at 2:45 AM
The way I hype up Louisville at biotech conferences... Louisville could be a great hub for more than just overnight sequencing y’all.
October 17, 2025 at 3:59 AM
Reposted by Emily Madden
Looks like @leandrosboukas.bsky.social has been busy doing useful stuff. DNV detection in duos, very valuable in communities in which families are less stable.

www.medrxiv.org/content/10.1...
Identification of de novo variants from parent-proband duos via long-read sequencing
While de novo variants cause many Mendelian disorders, their detection currently requires sequencing of the proband and both biological parents. This is not feasible when only one parent is available,...
www.medrxiv.org
October 11, 2025 at 12:26 PM
Reposted by Emily Madden
I have a fabulous undergrad who has a lot of experience with QIIME2 & using R to analyze microbiome data. She is looking for a job starting in January. Would love to learn more bench and field skills (will be getting some in her last 2 months). Open to academic, industry, government jobs in the US.
October 6, 2025 at 9:34 PM
Pushing the boundaries of science often means our language can’t keep up. Excited to be part of a team whose work with amazing collaborators advanced the field so much, it demanded a new shared language. Huge congrats to all involved!

www.sciencedirect.com/science/arti...
A needed nomenclature for nucleosomes
Histone post-translational modifications (PTMs) are crucial to eukaryotic genome regulation, with a range of reported functions and mechanisms of acti…
www.sciencedirect.com
October 2, 2025 at 8:00 PM
Hits on all the things that make RNA viruses the coolest things to study in biology. 😤
New preprint alert! 🦟 <-> 🦠 <-> 🧑

I am thrilled to share our latest study on alphavirus host adaptation. More specifically, on how a single codon helps blunt alphavirus-induced host innate immune responses in mosquito and human cells. Continue reading for more!

www.biorxiv.org/content/10.1...
The Sindbis virus nsP3 opal codon protects viral RNA and fitness by maintaining replication spherule integrity
Most alphaviruses encode an in-frame opal stop codon between nsP3 and nsP4 in their nsP ORF. This opal stop codon mediates a temperature-dependent balance between viral polymerase production and prote...
www.biorxiv.org
September 29, 2025 at 2:18 PM
Reposted by Emily Madden
UNC Biochemistry and Biophysics will soon post openings for tenure-track junior faculty positions! Information about the search is at this website: www.med.unc.edu/biochem/join.... The link to apply will be shared here too as soon as it's live. Join us!
Join Us | Biochemistry and Biophysics
Updated on September 26, 2025. This page will be updated again soon. Why Biochemistry and Biophysics (BCBP) at UNC?  BCBP is a premier department for basic mechanistic research into the molecular basi...
www.med.unc.edu
September 27, 2025 at 12:57 AM
Reposted by Emily Madden
🚀 Ordering lab supplies just got way easier in our lab.
We built a workflow (github.com/farnunglab/N...) where tapping an NFC tag on a reagent bottle automatically triggers an order request in Quartzy. No more scribbling notes or hunting for a computer. Here’s how 👇
September 26, 2025 at 1:15 PM