Eric Conway
@conwayer1.bsky.social
Group Leader Chromatin Architecture in Cancer Laboratory at UCD | Interested in Epigenetics, Chromatin, Transcription, Histone Modifications, Cancer | He/Him
Website: https://conwaychromatinlab.com/
Website: https://conwaychromatinlab.com/
Reposted by Eric Conway
We are excited to be bringing you two webinars from world leaders in epigenetics this month! 🧬
📅Feb 13th- Edith Heard from @crick.ac.uk
📅Feb 27th- @brianstrahl.bsky.social from @uncchapelhill.bsky.social
Don't miss out! See registration details below!
@activemotifusa.bsky.social
📅Feb 13th- Edith Heard from @crick.ac.uk
📅Feb 27th- @brianstrahl.bsky.social from @uncchapelhill.bsky.social
Don't miss out! See registration details below!
@activemotifusa.bsky.social
February 9, 2026 at 2:12 PM
We are excited to be bringing you two webinars from world leaders in epigenetics this month! 🧬
📅Feb 13th- Edith Heard from @crick.ac.uk
📅Feb 27th- @brianstrahl.bsky.social from @uncchapelhill.bsky.social
Don't miss out! See registration details below!
@activemotifusa.bsky.social
📅Feb 13th- Edith Heard from @crick.ac.uk
📅Feb 27th- @brianstrahl.bsky.social from @uncchapelhill.bsky.social
Don't miss out! See registration details below!
@activemotifusa.bsky.social
Reposted by Eric Conway
Just one week to go until Edith Heard will be joining us for the All-Ireland Chromatin Consortium webinar on 'The Epigenetic Dynamics of X Inactivation in Development and Disease' 🧬
Registration link: us06web.zoom.us/webinar/regi...
Registration link: us06web.zoom.us/webinar/regi...
February 6, 2026 at 11:07 AM
Just one week to go until Edith Heard will be joining us for the All-Ireland Chromatin Consortium webinar on 'The Epigenetic Dynamics of X Inactivation in Development and Disease' 🧬
Registration link: us06web.zoom.us/webinar/regi...
Registration link: us06web.zoom.us/webinar/regi...
Reposted by Eric Conway
Webinar reminder ⏰
Our first All-Ireland Chromatin Consortium webinar of the year, presented by Dr Lucas Farnung, is coming up this Friday at 4pm 📅 . Free registration details below, as well as links to download our new webinar calendar 👇
Our first All-Ireland Chromatin Consortium webinar of the year, presented by Dr Lucas Farnung, is coming up this Friday at 4pm 📅 . Free registration details below, as well as links to download our new webinar calendar 👇
After a short break in our webinars we are delighted to be back up & running this month!
First up, on Jan 30th we will be joined by @lucas.farnunglab.com from @harvardmed.bsky.social 🔬
Shortly after, on Feb 13th we will be hosting @heardlab.bsky.social from @crick.ac.uk 🧬
Registration details 👇
First up, on Jan 30th we will be joined by @lucas.farnunglab.com from @harvardmed.bsky.social 🔬
Shortly after, on Feb 13th we will be hosting @heardlab.bsky.social from @crick.ac.uk 🧬
Registration details 👇
January 26, 2026 at 10:57 AM
Webinar reminder ⏰
Our first All-Ireland Chromatin Consortium webinar of the year, presented by Dr Lucas Farnung, is coming up this Friday at 4pm 📅 . Free registration details below, as well as links to download our new webinar calendar 👇
Our first All-Ireland Chromatin Consortium webinar of the year, presented by Dr Lucas Farnung, is coming up this Friday at 4pm 📅 . Free registration details below, as well as links to download our new webinar calendar 👇
Super line-up of chromatin, epigenetics and gene regulation speakers coming your way from @aicc-ireland.bsky.social over the next 5 months!
After a short break in our webinars we are delighted to be back up & running this month!
First up, on Jan 30th we will be joined by @lucas.farnunglab.com from @harvardmed.bsky.social 🔬
Shortly after, on Feb 13th we will be hosting @heardlab.bsky.social from @crick.ac.uk 🧬
Registration details 👇
First up, on Jan 30th we will be joined by @lucas.farnunglab.com from @harvardmed.bsky.social 🔬
Shortly after, on Feb 13th we will be hosting @heardlab.bsky.social from @crick.ac.uk 🧬
Registration details 👇
January 15, 2026 at 3:19 PM
Super line-up of chromatin, epigenetics and gene regulation speakers coming your way from @aicc-ireland.bsky.social over the next 5 months!
Reposted by Eric Conway
🚨 Multiple #PhD opportunities for lab or computational applicants. Do you want to understand the molecular basis of #epigenetic dysfunction in human disease?
Come work with our group at the fantastic, collaborative @uoe-igc.bsky.social in a beautiful, liveable city.
🧵 1/4
Please repost 🙏
Come work with our group at the fantastic, collaborative @uoe-igc.bsky.social in a beautiful, liveable city.
🧵 1/4
Please repost 🙏
November 25, 2025 at 9:15 AM
🚨 Multiple #PhD opportunities for lab or computational applicants. Do you want to understand the molecular basis of #epigenetic dysfunction in human disease?
Come work with our group at the fantastic, collaborative @uoe-igc.bsky.social in a beautiful, liveable city.
🧵 1/4
Please repost 🙏
Come work with our group at the fantastic, collaborative @uoe-igc.bsky.social in a beautiful, liveable city.
🧵 1/4
Please repost 🙏
Reposted by Eric Conway
RESEARCH PAPER: Dominant-negative effects of Weaver syndrome-associated EZH2 variants
By Deevy et al., Eric Conway and Adrian Bracken
➡️ https://genesdev.cshlp.org/content/39/21-22/1355.full
Eric Conway
Adrian Bracken
#weaversyndrome #ezh2 #polycomb #mutation #congenitaldisorder #onthecover
By Deevy et al., Eric Conway and Adrian Bracken
➡️ https://genesdev.cshlp.org/content/39/21-22/1355.full
Eric Conway
Adrian Bracken
#weaversyndrome #ezh2 #polycomb #mutation #congenitaldisorder #onthecover
November 10, 2025 at 4:05 PM
RESEARCH PAPER: Dominant-negative effects of Weaver syndrome-associated EZH2 variants
By Deevy et al., Eric Conway and Adrian Bracken
➡️ https://genesdev.cshlp.org/content/39/21-22/1355.full
Eric Conway
Adrian Bracken
#weaversyndrome #ezh2 #polycomb #mutation #congenitaldisorder #onthecover
By Deevy et al., Eric Conway and Adrian Bracken
➡️ https://genesdev.cshlp.org/content/39/21-22/1355.full
Eric Conway
Adrian Bracken
#weaversyndrome #ezh2 #polycomb #mutation #congenitaldisorder #onthecover
We are delighted that @genesdev.bsky.social have selected our (w/ @adrianbracken.bsky.social) Weaver syndrome paper artwork as the November cover! This piece was made by my incredibly talented niece, Gina 'Dna Vinci' Ronan.
@ucddublin.bsky.social @tcddublin.bsky.social @ucd-sbbs.bsky.social
@ucddublin.bsky.social @tcddublin.bsky.social @ucd-sbbs.bsky.social
🚨 NEW ISSUE ALERT!!! 🚨
New Outlook, Review and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/21-22.toc
New Outlook, Review and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/21-22.toc
November 3, 2025 at 6:18 PM
We are delighted that @genesdev.bsky.social have selected our (w/ @adrianbracken.bsky.social) Weaver syndrome paper artwork as the November cover! This piece was made by my incredibly talented niece, Gina 'Dna Vinci' Ronan.
@ucddublin.bsky.social @tcddublin.bsky.social @ucd-sbbs.bsky.social
@ucddublin.bsky.social @tcddublin.bsky.social @ucd-sbbs.bsky.social
Reposted by Eric Conway
Paul Nurse describing the main job of a PI
(From ‘The Thinking Game’, 2024)
(From ‘The Thinking Game’, 2024)
October 31, 2025 at 8:45 AM
Paul Nurse describing the main job of a PI
(From ‘The Thinking Game’, 2024)
(From ‘The Thinking Game’, 2024)
Reposted by Eric Conway
1/ 🚀 AEBP2 isn’t what we thought.
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
October 31, 2025 at 10:53 AM
1/ 🚀 AEBP2 isn’t what we thought.
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
Second annual Conway/ Coughlan lab pumpkin carving competition this morning with plenty of coffee and treats to keep us going! Skills getting better every year.
Can anyone spot the nucleosomes?
@coughlan-lab.bsky.social
@ucddublin.bsky.social
@ucd-sbbs.bsky.social
Can anyone spot the nucleosomes?
@coughlan-lab.bsky.social
@ucddublin.bsky.social
@ucd-sbbs.bsky.social
October 30, 2025 at 2:25 PM
Second annual Conway/ Coughlan lab pumpkin carving competition this morning with plenty of coffee and treats to keep us going! Skills getting better every year.
Can anyone spot the nucleosomes?
@coughlan-lab.bsky.social
@ucddublin.bsky.social
@ucd-sbbs.bsky.social
Can anyone spot the nucleosomes?
@coughlan-lab.bsky.social
@ucddublin.bsky.social
@ucd-sbbs.bsky.social
Reposted by Eric Conway
Absolutely delighted to share our preprint, using functional genomics to uncover a novel dependency in lymphoma that can overcome resistance to targeted therapy. Grateful to co-first author @jamesnolan.bsky.social and co-senior authors @conwayer1.bsky.social and @adrianbracken.bsky.social see👇
🧵1/Exciting news in cancer epigenetics! Our latest research, "AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma", is now available on www.biorxiv.org/content/10.1.... Here's a thread summarizing our findings!👇
#CancerResearch #Epigenetics #Chromatin #Lymphoma
#CancerResearch #Epigenetics #Chromatin #Lymphoma
AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma
The catalytic subunit of Polycomb Repressive Complex 2 (PRC2), EZH2, is recurrently mutated in 25% of diffuse large B-cell lymphomas (DLBCL), causing increased H3K27me3 and decreased H3K27me2 levels. ...
www.biorxiv.org
October 17, 2025 at 2:07 PM
Absolutely delighted to share our preprint, using functional genomics to uncover a novel dependency in lymphoma that can overcome resistance to targeted therapy. Grateful to co-first author @jamesnolan.bsky.social and co-senior authors @conwayer1.bsky.social and @adrianbracken.bsky.social see👇
Reposted by Eric Conway
🧵1/Exciting news in cancer epigenetics! Our latest research, "AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma", is now available on www.biorxiv.org/content/10.1.... Here's a thread summarizing our findings!👇
#CancerResearch #Epigenetics #Chromatin #Lymphoma
#CancerResearch #Epigenetics #Chromatin #Lymphoma
AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma
The catalytic subunit of Polycomb Repressive Complex 2 (PRC2), EZH2, is recurrently mutated in 25% of diffuse large B-cell lymphomas (DLBCL), causing increased H3K27me3 and decreased H3K27me2 levels. ...
www.biorxiv.org
October 17, 2025 at 7:11 AM
🧵1/Exciting news in cancer epigenetics! Our latest research, "AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma", is now available on www.biorxiv.org/content/10.1.... Here's a thread summarizing our findings!👇
#CancerResearch #Epigenetics #Chromatin #Lymphoma
#CancerResearch #Epigenetics #Chromatin #Lymphoma
Our very own Evan Matthews, from @coughlan-lab.bsky.social, will be running the Dublin Marathon this month in aid of the Irish Cancer Society!
If you want to show Evan and the ICS your support you can donate through the link below!
eventmaster.ie/fundraising/...
@ucddublin.bsky.social
🏃💨
If you want to show Evan and the ICS your support you can donate through the link below!
eventmaster.ie/fundraising/...
@ucddublin.bsky.social
🏃💨
October 14, 2025 at 12:30 PM
Our very own Evan Matthews, from @coughlan-lab.bsky.social, will be running the Dublin Marathon this month in aid of the Irish Cancer Society!
If you want to show Evan and the ICS your support you can donate through the link below!
eventmaster.ie/fundraising/...
@ucddublin.bsky.social
🏃💨
If you want to show Evan and the ICS your support you can donate through the link below!
eventmaster.ie/fundraising/...
@ucddublin.bsky.social
🏃💨
Reposted by Eric Conway
There's a super line up next March for the Keystone meeting in Geneva for anyone interested in chromatin and epigenetics! Not a bad spot for a Spring trip!
🧬👇🇨🇭
#KSEpigenetics26 #epigenetics #chromatin #KeystoneSymposia
🧬👇🇨🇭
#KSEpigenetics26 #epigenetics #chromatin #KeystoneSymposia
Join us in Geneva (March, 2026) for the Keystone Symposium Epigenetics & Gene Regulation in Health and Disease, co-organized with @ckadoch.bsky.social — linking epigenetic mechanisms with therapeutic innovation. Apply for a short talk!
#KSEpigenetics26 #epigenetics #chromatin #KeystoneSymposia
#KSEpigenetics26 #epigenetics #chromatin #KeystoneSymposia
Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities | Keystone Symposia
Join us at the Keystone Symposia on Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities, March 2026, in Geneva, with field leaders!
keysym.us
October 14, 2025 at 9:31 AM
There's a super line up next March for the Keystone meeting in Geneva for anyone interested in chromatin and epigenetics! Not a bad spot for a Spring trip!
🧬👇🇨🇭
#KSEpigenetics26 #epigenetics #chromatin #KeystoneSymposia
🧬👇🇨🇭
#KSEpigenetics26 #epigenetics #chromatin #KeystoneSymposia
Reposted by Eric Conway
We are looking for a student to continue our work on chromatin evolution:
www.nature.com/articles/s41...
www.biorxiv.org/content/10.1...
The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes.
More info: recruitment.crg.eu/content/jobs...
www.nature.com/articles/s41...
www.biorxiv.org/content/10.1...
The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes.
More info: recruitment.crg.eu/content/jobs...
July 15, 2025 at 11:30 AM
We are looking for a student to continue our work on chromatin evolution:
www.nature.com/articles/s41...
www.biorxiv.org/content/10.1...
The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes.
More info: recruitment.crg.eu/content/jobs...
www.nature.com/articles/s41...
www.biorxiv.org/content/10.1...
The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes.
More info: recruitment.crg.eu/content/jobs...
Reposted by Eric Conway
👏 Congrats to @conwayer1.bsky.social on a major @genesdev.bsky.social publication!
In collab with @adrianbracken.bsky.social @tcddublin.bsky.social & Dr Orla Deevy @ucdscience.bsky.social, the team showed how EZH2 mutations disrupt PRC2, driving Weaver syndrome🧬
📖 Read more here ▶️bit.ly/3HL0YiI
In collab with @adrianbracken.bsky.social @tcddublin.bsky.social & Dr Orla Deevy @ucdscience.bsky.social, the team showed how EZH2 mutations disrupt PRC2, driving Weaver syndrome🧬
📖 Read more here ▶️bit.ly/3HL0YiI
August 27, 2025 at 3:20 PM
👏 Congrats to @conwayer1.bsky.social on a major @genesdev.bsky.social publication!
In collab with @adrianbracken.bsky.social @tcddublin.bsky.social & Dr Orla Deevy @ucdscience.bsky.social, the team showed how EZH2 mutations disrupt PRC2, driving Weaver syndrome🧬
📖 Read more here ▶️bit.ly/3HL0YiI
In collab with @adrianbracken.bsky.social @tcddublin.bsky.social & Dr Orla Deevy @ucdscience.bsky.social, the team showed how EZH2 mutations disrupt PRC2, driving Weaver syndrome🧬
📖 Read more here ▶️bit.ly/3HL0YiI
Delighted that our work on EZH2 dominant negativity in Weaver syndrome is now out in Genes & Development!
This exciting work on chromatinopathies 🧬 was in collab with @adrianbracken.bsky.social and spearheaded by Orla Deevy.
@ucddublin.bsky.social @ucd-sbbs.bsky.social
www.ucd.ie/newsandopini...
This exciting work on chromatinopathies 🧬 was in collab with @adrianbracken.bsky.social and spearheaded by Orla Deevy.
@ucddublin.bsky.social @ucd-sbbs.bsky.social
www.ucd.ie/newsandopini...
UCD co-lead breakthrough discovering genetic mechanism driving Weaver syndrome
www.ucd.ie
August 27, 2025 at 11:15 AM
Delighted that our work on EZH2 dominant negativity in Weaver syndrome is now out in Genes & Development!
This exciting work on chromatinopathies 🧬 was in collab with @adrianbracken.bsky.social and spearheaded by Orla Deevy.
@ucddublin.bsky.social @ucd-sbbs.bsky.social
www.ucd.ie/newsandopini...
This exciting work on chromatinopathies 🧬 was in collab with @adrianbracken.bsky.social and spearheaded by Orla Deevy.
@ucddublin.bsky.social @ucd-sbbs.bsky.social
www.ucd.ie/newsandopini...
Really excited to share the line up for this years @arrefoundation.bsky.social research symposium. It was a pleasure to contribute to putting the program together this year.
Looking forward to seeing everyone in Boston in October!
More details can be found here: asxlconference.org
Looking forward to seeing everyone in Boston in October!
More details can be found here: asxlconference.org
August 25, 2025 at 10:34 AM
Really excited to share the line up for this years @arrefoundation.bsky.social research symposium. It was a pleasure to contribute to putting the program together this year.
Looking forward to seeing everyone in Boston in October!
More details can be found here: asxlconference.org
Looking forward to seeing everyone in Boston in October!
More details can be found here: asxlconference.org
Amazing new initiative with a seriously impressive budget (€2.25M to 3.25M) to attract researchers to Ireland!
Would be great to get some more chromatin biologists here! 👀🧬
Would be great to get some more chromatin biologists here! 👀🧬
Research Ireland, on behalf of @deptoffhed.bsky.social, have today launched Global Talent Ireland - a new initiative to attract exceptional mid-career and established researchers from across the globe to Ireland.
For more information visit:
www.researchireland.ie/funding/glob...
For more information visit:
www.researchireland.ie/funding/glob...
Global Talent Ireland - Research Ireland
Global Talent Ireland aims to attract exceptional mid-career and established researchers from across the globe to Ireland. Researchers funded through this programme are required to transfer their rese...
www.researchireland.ie
July 18, 2025 at 10:53 AM
Amazing new initiative with a seriously impressive budget (€2.25M to 3.25M) to attract researchers to Ireland!
Would be great to get some more chromatin biologists here! 👀🧬
Would be great to get some more chromatin biologists here! 👀🧬
Great to enjoy the last of the Irish summer with a lab BBQ to celebrate paper acceptance 🎉 and individual grant/ travel/ poster prizes over the last few months! ☀️ 🍖 🍻
@coughlan-lab.bsky.social
@coughlan-lab.bsky.social
July 17, 2025 at 3:09 PM
Great to enjoy the last of the Irish summer with a lab BBQ to celebrate paper acceptance 🎉 and individual grant/ travel/ poster prizes over the last few months! ☀️ 🍖 🍻
@coughlan-lab.bsky.social
@coughlan-lab.bsky.social
Reposted by Eric Conway
I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org
June 20, 2025 at 1:24 PM
I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org
Reposted by Eric Conway
Big congratulations to best poster and best talk award winners @samrustichelli.bsky.social (Diego Pasini lab,IEO)
and Mike Rainey (Corrado Santocanale lab) @uniofgalway.bsky.social
🏆🏆
and Mike Rainey (Corrado Santocanale lab) @uniofgalway.bsky.social
🏆🏆
June 4, 2025 at 12:17 PM
Big congratulations to best poster and best talk award winners @samrustichelli.bsky.social (Diego Pasini lab,IEO)
and Mike Rainey (Corrado Santocanale lab) @uniofgalway.bsky.social
🏆🏆
and Mike Rainey (Corrado Santocanale lab) @uniofgalway.bsky.social
🏆🏆
Reposted by Eric Conway
Looking back on a super day at the AICC symposium one week on 🤩 many thanks to @tcddublin.bsky.social micro department for hosting and to our sponsors @epicypher.bsky.social & @novogene-europe.bsky.social.
Thanks to all attendees, we hope to see again in May next year🌞
Thanks to all attendees, we hope to see again in May next year🌞
June 4, 2025 at 12:17 PM
Looking back on a super day at the AICC symposium one week on 🤩 many thanks to @tcddublin.bsky.social micro department for hosting and to our sponsors @epicypher.bsky.social & @novogene-europe.bsky.social.
Thanks to all attendees, we hope to see again in May next year🌞
Thanks to all attendees, we hope to see again in May next year🌞
Reposted by Eric Conway
New Novogene freebies 🥰
I am going to be at the All-Ireland Chromatin Consortium #AICC25 in Trinity College Dublin this Wednesday. @tcddublin.bsky.social
Please come by and say hi, and pick up some of these new freebies.
@aicc-ireland.bsky.social @novogene-europe.bsky.social
I am going to be at the All-Ireland Chromatin Consortium #AICC25 in Trinity College Dublin this Wednesday. @tcddublin.bsky.social
Please come by and say hi, and pick up some of these new freebies.
@aicc-ireland.bsky.social @novogene-europe.bsky.social
May 26, 2025 at 2:51 PM
New Novogene freebies 🥰
I am going to be at the All-Ireland Chromatin Consortium #AICC25 in Trinity College Dublin this Wednesday. @tcddublin.bsky.social
Please come by and say hi, and pick up some of these new freebies.
@aicc-ireland.bsky.social @novogene-europe.bsky.social
I am going to be at the All-Ireland Chromatin Consortium #AICC25 in Trinity College Dublin this Wednesday. @tcddublin.bsky.social
Please come by and say hi, and pick up some of these new freebies.
@aicc-ireland.bsky.social @novogene-europe.bsky.social
Reposted by Eric Conway
Only 5 days to go until our flagship event of the year!
May 23, 2025 at 9:31 AM
Only 5 days to go until our flagship event of the year!