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conwayer1.bsky.social
Eric Conway
@conwayer1.bsky.social
590 followers 330 following 42 posts
Group Leader Chromatin Architecture in Cancer Laboratory at UCD | Interested in Epigenetics, Chromatin, Transcription, Histone Modifications, Cancer | He/Him
Website: https://conwaychromatinlab.com/
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Reposted by Eric Conway
genesdev.bsky.social
RESEARCH PAPER: Dominant-negative effects of Weaver syndrome-associated EZH2 variants
By Deevy et al., Eric Conway and Adrian Bracken
➡️ https://genesdev.cshlp.org/content/39/21-22/1355.full

Eric Conway
Adrian Bracken

#weaversyndrome #ezh2 #polycomb #mutation #congenitaldisorder #onthecover
November 10, 2025 at 4:05 PM
conwayer1.bsky.social
We are delighted that @genesdev.bsky.social have selected our (w/ @adrianbracken.bsky.social) Weaver syndrome paper artwork as the November cover! This piece was made by my incredibly talented niece, Gina 'Dna Vinci' Ronan.

@ucddublin.bsky.social @tcddublin.bsky.social @ucd-sbbs.bsky.social
genesdev.bsky.social Genes & Development @genesdev.bsky.social · 7d
🚨 NEW ISSUE ALERT!!! 🚨

New Outlook, Review and Research articles online now at Genes & Development.

Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/21-22.toc
November 3, 2025 at 6:18 PM
Reposted by Eric Conway
christophertape.bsky.social
Paul Nurse describing the main job of a PI

(From ‘The Thinking Game’, 2024)
October 31, 2025 at 8:45 AM
Reposted by Eric Conway
adrianbracken.bsky.social
1/ 🚀 AEBP2 isn’t what we thought.

You were told that AEBP2 promotes PRC2 activity on chromatin.

We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.

👉 surl.li/cgwqcq

A thread 🧵
October 31, 2025 at 10:53 AM
conwayer1.bsky.social
Second annual Conway/ Coughlan lab pumpkin carving competition this morning with plenty of coffee and treats to keep us going! Skills getting better every year.

Can anyone spot the nucleosomes?

@coughlan-lab.bsky.social
@ucddublin.bsky.social
@ucd-sbbs.bsky.social
October 30, 2025 at 2:25 PM
Reposted by Eric Conway
dr-chromatin.bsky.social
Absolutely delighted to share our preprint, using functional genomics to uncover a novel dependency in lymphoma that can overcome resistance to targeted therapy. Grateful to co-first author @jamesnolan.bsky.social and co-senior authors @conwayer1.bsky.social and @adrianbracken.bsky.social see👇
October 17, 2025 at 2:07 PM
Reposted by Eric Conway
jamesnolan.bsky.social
🧵1/Exciting news in cancer epigenetics! Our latest research, "AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma", is now available on www.biorxiv.org/content/10.1.... Here's a thread summarizing our findings!👇
#CancerResearch #Epigenetics #Chromatin #Lymphoma
AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma
The catalytic subunit of Polycomb Repressive Complex 2 (PRC2), EZH2, is recurrently mutated in 25% of diffuse large B-cell lymphomas (DLBCL), causing increased H3K27me3 and decreased H3K27me2 levels. ...
www.biorxiv.org
October 17, 2025 at 7:11 AM
conwayer1.bsky.social
Our very own Evan Matthews, from @coughlan-lab.bsky.social, will be running the Dublin Marathon this month in aid of the Irish Cancer Society!

If you want to show Evan and the ICS your support you can donate through the link below!

eventmaster.ie/fundraising/...

@ucddublin.bsky.social

🏃💨
October 14, 2025 at 12:30 PM
Reposted by Eric Conway
aicc-ireland.bsky.social
There's a super line up next March for the Keystone meeting in Geneva for anyone interested in chromatin and epigenetics! Not a bad spot for a Spring trip!

🧬👇🇨🇭

#KSEpigenetics26 #epigenetics #chromatin #KeystoneSymposia
October 14, 2025 at 9:31 AM
Reposted by Eric Conway
arnausebe.bsky.social
We are looking for a student to continue our work on chromatin evolution:
www.nature.com/articles/s41...
www.biorxiv.org/content/10.1...

The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes.

More info: recruitment.crg.eu/content/jobs...
July 15, 2025 at 11:30 AM
Reposted by Eric Conway
ucd-sbbs.bsky.social
👏 Congrats to @conwayer1.bsky.social on a major @genesdev.bsky.social‬ publication!

In collab with @adrianbracken.bsky.social @tcddublin.bsky.social & Dr Orla Deevy @ucdscience.bsky.social, the team showed how EZH2 mutations disrupt PRC2, driving Weaver syndrome🧬

📖 Read more here ▶️bit.ly/3HL0YiI
August 27, 2025 at 3:20 PM
conwayer1.bsky.social
Delighted that our work on EZH2 dominant negativity in Weaver syndrome is now out in Genes & Development!

This exciting work on chromatinopathies 🧬 was in collab with @adrianbracken.bsky.social and spearheaded by Orla Deevy.

@ucddublin.bsky.social @ucd-sbbs.bsky.social

www.ucd.ie/newsandopini...
UCD co-lead breakthrough discovering genetic mechanism driving Weaver syndrome
www.ucd.ie
August 27, 2025 at 11:15 AM
conwayer1.bsky.social
Really excited to share the line up for this years @arrefoundation.bsky.social research symposium. It was a pleasure to contribute to putting the program together this year.

Looking forward to seeing everyone in Boston in October!

More details can be found here: asxlconference.org
August 25, 2025 at 10:34 AM
conwayer1.bsky.social
Amazing new initiative with a seriously impressive budget (€2.25M to 3.25M) to attract researchers to Ireland!

Would be great to get some more chromatin biologists here! 👀🧬
July 18, 2025 at 10:53 AM
conwayer1.bsky.social
Great to enjoy the last of the Irish summer with a lab BBQ to celebrate paper acceptance 🎉 and individual grant/ travel/ poster prizes over the last few months! ☀️ 🍖 🍻

@coughlan-lab.bsky.social
July 17, 2025 at 3:09 PM
Reposted by Eric Conway
thecocodium.bsky.social
I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org
June 20, 2025 at 1:24 PM
Reposted by Eric Conway
aicc-ireland.bsky.social
Big congratulations to best poster and best talk award winners @samrustichelli.bsky.social (Diego Pasini lab,IEO)
and Mike Rainey (Corrado Santocanale lab) @uniofgalway.bsky.social
🏆🏆
June 4, 2025 at 12:17 PM
Reposted by Eric Conway
aicc-ireland.bsky.social
Looking back on a super day at the AICC symposium one week on 🤩 many thanks to @tcddublin.bsky.social micro department for hosting and to our sponsors @epicypher.bsky.social & @novogene-europe.bsky.social.

Thanks to all attendees, we hope to see again in May next year🌞
June 4, 2025 at 12:17 PM
Reposted by Eric Conway
stevestockdale.bsky.social
New Novogene freebies 🥰

I am going to be at the All-Ireland Chromatin Consortium #AICC25 in Trinity College Dublin this Wednesday. @tcddublin.bsky.social

Please come by and say hi, and pick up some of these new freebies.

@aicc-ireland.bsky.social @novogene-europe.bsky.social
May 26, 2025 at 2:51 PM
Reposted by Eric Conway
aicc-ireland.bsky.social
Only 5 days to go until our flagship event of the year!
May 23, 2025 at 9:31 AM
Reposted by Eric Conway
ucd-sbbs.bsky.social
🎉 Huge congrats to our 3 #PhD students

⭐Grace Ruddin ⭐
⭐Rhys Orimaco⭐
⭐Molly Davies⭐

who each won a prize for their presentations at yesterday’s SBBS Research Day 2025 🏆🧪

🔗 lnkd.in/e2-WFaug

@ucdscience.bsky.social @ucdresearch.bsky.social @ucddublin.bsky.social

#SBBSRD2025 #UCDResearch
May 2, 2025 at 11:40 AM
conwayer1.bsky.social
Awesome to be able to share our work on PAX8 in high-grade serous ovarian cancer, super job @daviesmolly13.bsky.social! Thanks for the opportunity to share @gensocuk.bsky.social

@ucd-sbbs.bsky.social @ucdresearch.bsky.social
gensocuk.bsky.social Genetics Society UK @gensocuk.bsky.social · Apr 25
Last morning of the conference with Molly Davies talking about how PAX8 coordinates oncogenic transcription independently of stable interactors in high-grade serous ovarian cancer #Epigenetics2025
April 25, 2025 at 11:55 AM
Reposted by Eric Conway
aicc-ireland.bsky.social
We are very excited to launch the registration for our 2025 symposium on 'Chromatin, Epigenetics and Transcription' today!

Join us at @tcddublin.bsky.social on May 28th for this event featuring keynote, new PI and PhD/postdoc talks and posters!

allirelandchromatinconsortium.ie/annual-meeti...
March 24, 2025 at 12:03 PM
Reposted by Eric Conway
ucd-sbbs.bsky.social
🎉ENGAGE Finalist Spotlight! ⭐

📢Introducing Finalist #4: Emma Doyle 🧬

🔬 Emma explains CRISPR gene editing and how it’s unlocking powerful discoveries in biomedical research

📅 Catch her live in UCD or online at 5pm Wed April 16👇
www.ucd.ie/sbbs/newsand...

#AccessibleScience @conwayer1.bsky.social
April 10, 2025 at 2:13 PM
Reposted by Eric Conway
ucd-sbbs.bsky.social
🎉ENGAGE Finalist Spotlight!⭐

📢Introducing Finalist #3: Molly Davies 🎗️

🧬 Molly investigates how ovarian cancer rewires DNA structure—giving new insights into tumour behaviour🧫

📅 Don’t miss her talk at the ENGAGE Final, 5pm April 16 at UCD or online👇
www.ucd.ie/sbbs/newsand...
#AccessibleScience
April 10, 2025 at 10:41 AM