Don Sharkey
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donsharkey.bsky.social
Don Sharkey
@donsharkey.bsky.social
Prof of Neonatal Medicine & Technologies @Uni Nottingham. Views my own. Neonatal technologies & transport research.
Pinned
So the new scrubs have arrived! We move into our new futuristic NICU next week @ Nottingham Centre for Newborn Care. So, so excited for our babies, families and staff.
Reposted by Don Sharkey
Our BiB trial manuscript now published in JAMA...Early Intratracheal Budesonide for Bronchopulmonary Dysplasia url: jamanetwork.com/journals/jam...
Early Intratracheal Budesonide for Bronchopulmonary Dysplasia
This randomized clinical trial conducted at centers of the United States Neonatal Research Network assesses whether early intratracheal administration of a combination of budesonide mixed with surfact...
jamanetwork.com
September 30, 2025 at 3:19 PM
Reposted by Don Sharkey
Our September newsletter is now available!

Read this month's issue here for news, upcoming events, funding opportunities and recent publications in child health 👉 mailchi.mp/d56096f82afc...
September 29, 2025 at 11:00 AM
Reposted by Don Sharkey
Editor-in-Chief Eric Rubin asks why, under an administration that says it is focused on making America healthy again, we are denigrating and discarding our single most cost-effective public health tools — vaccines. Read the full editorial: nej.md/4mtH8Xm

#MedSky #PublicHealth
September 25, 2025 at 1:00 PM
Sad to see this come to fruition. @stefanjohansson.nicuverse.org.ap.brid.gy your analysis gets a mention but despite the strengths it is dismissed...😔
September 23, 2025 at 11:43 AM
Very thorough review and highlights early challenges FGR infants need to overcome. As highlighted, tricky to identify who truly is FGR vs constitutionally small.
NEW PAPER

Compromised cardiopulmonary transition in fetal growth restricted and small for gestational age neonates

Suboptimal fetal growth → altered cardiac structure/function → higher risk of impaired adaptation at birth, respiratory morbidity, and long-term CV risk.

doi.org/10.1113/JP28...
Compromised cardiopulmonary transition in fetal growth restricted and small for gestational age neonates
Abstract figure legend Differences in cardiovascular function between appropriately grown (AG) and fetal growth restricted (FGR) infants after the cardiopulmonary transition at birth. AG infants typi....
doi.org
September 16, 2025 at 7:46 AM
Early days but a promising approach. Likely to be more challenging in my population of newborn infants but would be great to explore....
A soft, robotic device can autonomously navigate the trachea to support rapid and self-guided intubation outside of hospitals and could expand and democratize intubation for emergency responders and resource-limited environments. #ScienceTranslationalMedicine https://scim.ag/4n0bxxt
September 15, 2025 at 7:56 PM
I've listened to almost all of these and they are great. Chatting about neonatal research and care. Well worth a listen for all involved in the care of newborns. Good work Mario and @espr-esn.bsky.social
🚀 Now live! Listen to Prof Dr Barbara Schmidt on #NeonatologyNow. Today's topic: Apnoea of prematurity and the use of caffeine for #preterm infants below 30 weeks of gestation. Tune in to hear Dr Schmidt's suggestions for preterms with a diagnosis of #apnea. 🎧 #NeonatalHealth #Neonatology #Podcast
August 29, 2025 at 12:54 PM
Really interesting study pushing the boundaries on this tricky and often poor outcome condition. Perhaps a condition that one day will have a handful of centres with expertise to treat and hopefully improve outcomes.
jama.com JAMA @jama.com · Aug 11
In utero embolization for vein of Galen malformation is feasible and may reduce mortality and neurodevelopmental delays, but poses a risk of unscheduled, preterm delivery.

ja.ma/45v3hOy
August 11, 2025 at 9:19 PM
Reposted by Don Sharkey
The win ratio method is gaining traction in #RCTs. Is it just a trend or a smarter way to look at composite hierarchical outcomes? We break it down in our latest Stats, STAT!📊 in NEJM Evidence. youtube.com/watch?v=jKtF... #stats @nejm.org @sarahgorey.bsky.social @chardin.bsky.social @ai.nejm.org
How Win Ratios Work | NEJM Evidence
YouTube video by NEJM Group
youtube.com
July 31, 2025 at 11:41 AM
Reposted by Don Sharkey
Ivermectin is an antiparasitic drug that kills mosquitoes feeding on treated persons. In this trial in Kenya, ivermectin given once per month for 3 months led to a 26% lower incidence of malaria than albendazole. Full trial results: nej.md/4lIyNzB

#MedSky #IDSky
July 23, 2025 at 9:10 PM
Reposted by Don Sharkey
Well done to Hannah Mitchell & her great team who produced this hugely important work:

Contribution of ethnicity and deprivation to paediatric critical care outcomes in the UK, 2008–21: a national retrospective cohort study - The Lancet Child & Adolescent Health www.thelancet.com/journals/lan...
Contribution of ethnicity and deprivation to paediatric critical care outcomes in the UK, 2008–21: a national retrospective cohort study
Variation in PICU mortality by ethnicity and area-level deprivation highlights the importance of further investigation into systemic drivers of disparities in PICU outcomes in the UK. Targeted strateg...
www.thelancet.com
July 11, 2025 at 7:20 PM
Impressive technological advancement.
jama.com JAMA @jama.com · Jul 8
Robotic surgery for middle or low rectal cancer demonstrated lower 3-year locoregional recurrence rates and improved functional outcomes compared with conventional laparoscopic surgery.

https://ja.ma/4eDwStq
July 8, 2025 at 11:51 AM
Reposted by Don Sharkey
Check out our new open access paper in @pediatricresearch.bsky.social . Highlighting the impact on thermal management, HIE and transport metrics following implementation of active therapeutic hypothermia by regional transport and referring centres for infants transferred for neo HIE rdcu.be/etXDT
Implementation of active therapeutic hypothermia across a regional transport network for infants transferred for neonatal encephalopathy
Pediatric Research - Implementation of active therapeutic hypothermia across a regional transport network for infants transferred for neonatal encephalopathy
rdcu.be
June 29, 2025 at 9:01 AM
Fabulous week hosted by @research4babies.bsky.social in Canada with our team member Syed, neonatal clinical fellow. Great hospitality Georg. Some amazing data on our new neonatal vital signs patch during cardiac arrest scenarios. Thanks for looking after Syed for another couple of weeks!
June 14, 2025 at 7:42 PM
Reposted by Don Sharkey
The evidence on infection outcomes of hospital-initiated kangaroo care is unclear.

In @lancetchildadol.bsky.social, authors evaluate the role of hospital-initiated kangaroo care in preventing mortality, sepsis, and invasive infection in low-birthweight infants: tinyurl.com/46aunenf
May 29, 2025 at 11:01 AM
Reposted by Don Sharkey
Delighted to see the @nihr funded CCD study published today in @lancetrh-europe.bsky.social

Lots to celebrate: sex, ethnicity and IMD does not impact time to diagnosis for CYP w cancer.

But also lots to improve: young people and certain diagnostic groups need urgent attention.

#earlydiagnosis
May 28, 2025 at 5:41 PM
Very interesting analysis. 3% difference in mortality if PDA actively treated. Perhaps results in more morbidity in expectant group survivors - not the case. One for the reading pile....
New meta-analysis on PDA management suggesting harm associated with active treatment compared to expectant management
jamanetwork.com/journals/jam...
May 28, 2025 at 12:41 PM
Wonderful, getting over many challenges to reach this accolade- well done!
What is it like working in as an international neonatal nurse in the UK?

In our latest blog, find out more about the career of NNA Nurse of the Year 2024 Rachna Sharma, who arrived in England in 2010.

Read Rachna's blog here: nna.org.uk/working-as-a...

#InternationalNurse
May 23, 2025 at 4:59 PM
Reposted by Don Sharkey
We’re honoured to receive a Medilink Midlands Business Award with the University of Nottingham, celebrating our collaboration in the Partnership Between Academia and Business category.
May 19, 2025 at 8:39 AM
Such a powerful tool. MRI born in my University, really recommend watching this fascinating 3 min video of where it started. Never be able to do research like this now, "I may have a cardiac arrest"! The images have moved on somewhat and we are just installing an 11T! m.youtube.com/watch?v=3nIX...
May 18, 2025 at 6:54 PM
Strong conclusions "Their use should be standard of care for very preterm infants, or offering their use to parents should be standard practice. Just don’t expect them to improve neurological or developmental outcomes" - do you agree?
May 15, 2025 at 8:34 AM
Reposted by Don Sharkey
🚀 Today, we launch #ForgingAhead—a £16M initiative uniting 15 Midlands universities.

The project will transform the commercialisation ecosystem by:

🔹 Developing top-tier talent
🔹 Scaling accelerators
🔹 Attracting investment
🔹 Boosting key sectors

🔗 Read more: buff.ly/WyGEssg
‘Forging Ahead’ initiative to transform innovation and entrepreneurship across the Midlands - Midlands Innovation
‘Forging Ahead’ initiative to transform innovation and entrepreneurship across the Midlands
midlandsinnovation.org.uk
May 9, 2025 at 11:22 AM
What a refreshing read. Could apply in many settings. This "Forget the idea that a bubble bath or an essential oil diffuser will magically solve this." is so true. Recommend you read and share.
Parental burnout doesn’t always look like a meltdown. Sometimes it’s just staring at the wall while your tea goes cold. If you’re feeling stretched too thin, this one’s for you.

open.substack.com/pub/profafif...
How to Sense Your Own Parental Burnout Before It Takes Over
and ways to deal with it
open.substack.com
April 17, 2025 at 6:03 PM
Reposted by Don Sharkey
🧠 ESPR Special Interest Groups (SIGs) are where ideas grow into action!
✨ 15+ SIGs covering everything from brain imaging to QI & Innovation and beyond
🌍 Connect with experts, contribute to guidelines, shape the future of paediatrics
🔗 Explore & join: www.espr.eu/SIGs/SIG_ove...
April 7, 2025 at 4:51 PM