davidweinshenker.bsky.social
@davidweinshenker.bsky.social
Reposted
PSA for all #microglia lovers: certain Iba1 antibodies (see our new paper below for details) label not only microglia, but also vasopressin neurons, at least in mice. Brain region and species matter. A friendly reminder to always validate your antibodies! 🔬

www.eneuro.org/content/13/2...
A Common Iba1 Antibody Labels Vasopressin Neurons in Mice
There are a wide variety of commercially available antibodies for labeling microglial cells based on different protein targets, as well as antibodies for the same protein target made in different spec...
www.eneuro.org
February 3, 2026 at 9:36 PM
Excited to share newly minted PhD Anu Korukonda's tour de force thesis work describing the impact of pathogenic tau on #locuscoeruleus function in a mouse model of early #Alzheimers. A must for #BlueSpot researchers! www.biorxiv.org/content/10.6...

1/3
www.biorxiv.org
February 2, 2026 at 1:12 PM
Reposted
🧵Good news out of #NIH today.
(1) NIH is extending #ESI and #K99/R00 eligibility to accommodate researchers whose eligibility would have ended during the previous shutdown. Take a look at NOT-OD-26-020. If your ESI status would have ended in 2025, you get an automatic extension through 2026/03/31.
NOT-OD-26-020: Notice of Temporary Extension to Early-Stage Investigator (ESI) Eligibility Period
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Temporary Extension to Early-Stage Investigator (ESI) Eligibility Period NOT-OD-26-020. OD
grants.nih.gov
January 30, 2026 at 7:34 PM
Reposted
👇New biosketch requirement update.

“After evaluating the number and types of recent technical inquiries we received to both the SciENcv and eRA Service Desks, we recognize the difficulties these issues have had on the community’s ability to comply with the original timeline of January 25, 2026.”
👇
"NIH will provide a warning when the Common Forms are not used but will not withdraw applications that don’t comply with the use of the Common Forms. We expect the leniency to be in place through May 2026"

grants.nih.gov/faqs#/common...
Frequently Asked Questions (FAQs) | Grants & Funding
grants.nih.gov
January 29, 2026 at 10:08 PM
Reposted
Adolescent Social Isolation Facilitates Tau Spread in Raphe Nuclei Linking Depression and Hyperalgesia in Alzheimers Disease https://www.biorxiv.org/content/10.64898/2026.01.23.701108v1
January 26, 2026 at 6:15 AM
Reposted
The Neuromodulatory Subcortical Systems PIA within @istaart.bsky.social is requesting nominations for the best paper of 2025 on neuromodulatory subcortical systems in Alzheimer's disease!! ISTAART members: promote the work of your colleagues (or yourself) here: alz.surveymonkey.com/r/Publicatio...
Publication of the Year Award - Nomination
Thank you for submitting your Nomination!
alz.surveymonkey.com
January 21, 2026 at 7:07 PM
Reposted
Applications for our summer internship program are open. This is a paid, 9 week experience designed to provide research experience to undergraduates interested in the neurosciences, especially as related to the molecular and cellular basis of neuropsychiatric disorders

www.libd.org/summer-inter...
Summer Internship
Summer internship
www.libd.org
January 21, 2026 at 1:54 PM
Reposted
Congrats to all of the new @acnporg.bsky.social Members!!!
#ACNP2026
January 15, 2026 at 1:26 PM
Fun tennis with Mark Thomas at #ACNP2026!
January 13, 2026 at 12:00 AM
Weinshenker lab representing at #ACNP2026. Come say hi!
January 10, 2026 at 9:41 PM
Reposted
@mcwpharm-tox.bsky.social will be recruiting a mid-career translational neuropharmacologist with a research program focused on SUDs and/or stress-related disorders. Great opportunity in a growing and supportive dept. @davidbaranger.bsky.social and I will be at #ACNP. Reach out if you want to talk!
January 9, 2026 at 4:31 AM
Reposted
If you are submitting an NIH grant in February, you will be required to use SciENcv to prepare you biosketch.

IT IS MUCH WORSE THAN YOU CAN POSSIBLY IMAGINE.

Set aside *at least* 4 hours just to transfer an existing an biosketch into SciENcv.
January 6, 2026 at 11:29 PM
Reposted
Reposting this postdoc position, we are still reviewing applications. I will also be at Human Amyloid Imaging from 1/12 till 1/15 and happy to meet.
Postdoc position: our team is looking for a postdoctoral colleague interested in developing and testing theories of brainstem function in AD using fMRI/PET. The Martinos Center / MGH in Boston is a superb place to work. Reach out if you have any questions. Come and join us! 🎉🔵
January 5, 2026 at 5:38 PM
Reposted
If you have some time off these holidays have another look at our beautiful review on #LC neuropeptides 🔵🧠
Neuropeptides fine-tune the brain’s noradrenergic centre. This review maps how they regulate the locus coeruleus to shape behaviour. #PharmRev Danai Riga 🧪

https://ow.ly/SrCq50XMrCq
December 29, 2025 at 3:49 PM
Reposted
Postdoctoral fellowship available in structure guided drug discovery in @RothLabUNC
Please RT
December 27, 2025 at 3:51 PM
Reposted
The #NIH IRP Summer (paid!) Internship Program for 2026 has opened its application portal. This opportunity is open to US Citizens who are college students (including rising first-years), postbaccalaureate, and graduate students, including medical and dental. The deadline is 2026/02/18!
Become a Summer Intern in DCEG
DCEG offers a summer research internship in cancer epidemiology, biostatistics, or genetics fo college, postbaccalaureate masters-level students, and graduate students, including medical and dental st...
dceg.cancer.gov
December 15, 2025 at 6:01 PM
Reposted
Excited to bring large-scale automation to organoid culture at the Emory Brain Organoid Hub!
Thrilled to announce the Brain Organoid Hub at Emory has acquired CellXpress.ai! 🎉

Funded by an NIH S10 grant, this AI-powered platform automates cell culture, accelerates imaging, and streamlines analysis, enabling reproducible data and new research approaches.

Read more here: bit.ly/4qf3LBn
New automated cell culture system facilitates advanced organoid research | Emory University | Atlanta GA
Emory neuroscientists have installed a $1.5 million automated cell culture system designed specifically for human organoids, used to study diseases, test drugs, and develop regenerative therapies. The...
news.emory.edu
December 15, 2025 at 2:53 PM
Reposted
Thrilled this is out, led by former PD Cameron Ogg (now with her own lab at @rhodescollege.bsky.social!). It was a driven by a desire to see, in real-time, how LC activity/NE release influences downstream targets in behaving animals. SO hard to do, but Cameron did it! www.cell.com/cell-reports...
Locus coeruleus norepinephrine neurons facilitate orbitofrontal cortex remapping and behavioral flexibility
Ogg et al. use in vivo imaging techniques to record activity in the locus coeruleus (LC) and the orbitofrontal cortex (OFC) during a reversal learning task in freely moving rodents. They show that man...
www.cell.com
December 15, 2025 at 2:47 PM
Reposted
🧠 We're hiring! 🧠 Are you passionate about neuroscience and education? Join our faculty at UNC Chapel Hill to inspire and teach the next generation of neuroscientists. Apply now: 🔗​​https://unc.peopleadmin.com/postings/308455

#Neuroscience #TeachingJobs #AcademicJobs #HigherEd
December 9, 2025 at 7:20 PM
Reposted
Postdoc position: our team is looking for a postdoctoral colleague interested in developing and testing theories of brainstem function in AD using fMRI/PET. The Martinos Center / MGH in Boston is a superb place to work. Reach out if you have any questions. Come and join us! 🎉🔵
December 5, 2025 at 10:56 PM
Reposted
Department of Psychological & Brain Sciences at Johns Hopkins is inviting applications for 3 open-rank tenured/tenure-track positions in (1) Behavioral Neuroscience, (2) Cognitive Neuroscience, and (3) Cognitive Psychology.

pbs.jhu.edu/about/jobs/
Jobs | Psychological & Brain Sciences
Tenured/Tenure-track position in Cognitive Psychology Open Date Dec 01, 2025 Salary Range or Pay Grade The expected academic base salary range for this position is $110,000- $144,500 (Assistant Profes...
pbs.jhu.edu
December 2, 2025 at 12:00 AM
Reposted
Very proud of our PhD-student Yuliya Patsyuk's first publication: Locus coeruleus-entorhinal cortex tract integrity is linked to plasma tau and GFAP: alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
🔵 🎉
Locus coeruleus‐entorhinal cortex tract integrity is linked to plasma tau and glial fibrillary acidic protein
INTRODUCTION Pretangle tau inclusions from the locus coeruleus (LC) are hypothesized to propagate to the entorhinal cortex (EC) via neuron-to-neuron transmission along its projections. The lower int...
alz-journals.onlinelibrary.wiley.com
November 30, 2025 at 8:52 PM
Reposted
We’ll be hosting a free bicycle maintenance workshop soon that’s completely free. DM if you’d like to volunteer.

Marietta Bike Social: We ride every Saturday at 10AM, rain or shine, outside Marietta Square Market. Bring that fussy baby and let the sunshine and fresh air lull them into a good nap.
November 23, 2025 at 11:51 PM
Reposted
New pre-print led by the talented undergrad Alexia with @davidweinshenker.bsky.social

We used chronic DSP-4 treatment to lesion the LC-NE system in young TgF344-AD rats to see whether early degeneration led to accelerated onset of pathology and behavioral deficits.

www.biorxiv.org/content/10.1...
Impact of early locus coeruleus lesions in the TgF344 Alzheimer’s disease rat model
INTRODUCTION In murine models of Alzheimer’s disease (AD), lesioning the locus coeruleus-norepinephrine (LC-NE) system with DSP-4 exacerbates AD-like neuropathology and cognitive impairment. However, ...
www.biorxiv.org
November 15, 2025 at 7:04 PM
At #SFN2025 and interersted in the 🔵? Check out posters from Leslie Hassanein (D52; neuromelanin in the mouse locus coeruleus) and Maggie Tish (C59; human 3D locus coeruleus organoids) today from 1:00-5:00!
November 15, 2025 at 12:47 PM