Christin Herrmann
@christinviral.bsky.social
Scientist with Victor Torres in the Department of Host Microbe Interactions at St. Jude. Postdoc in the Cadwell Lab (NYU and UPenn) and grad school in the Weitzman Lab (UPenn).
Reposted by Christin Herrmann
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
October 4, 2025 at 6:44 PM
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
Reposted by Christin Herrmann
I'm thrilled to announce I'll be joining the Department of Molecular Genetics & Microbiology at the University of Florida in January 2026! My lab will study RNA virus-host interactions with a particular focus on the spatial regulation of viral replication and innate immune activation. genoyerlab.com
Genoyer Lab
genoyerlab.com
October 3, 2025 at 6:10 PM
I'm thrilled to announce I'll be joining the Department of Molecular Genetics & Microbiology at the University of Florida in January 2026! My lab will study RNA virus-host interactions with a particular focus on the spatial regulation of viral replication and innate immune activation. genoyerlab.com
Reposted by Christin Herrmann
Excited to share this collaborative study with @ritatamayo.bsky.social showing that E. faecalis influences C. diff morphology through the phase variable CmrRST system! This work was co-led by the amazing team of @ashleyweiss.bsky.social and Jilarie Santos-Santiago!
Enterococcus faecalis modulates phase variation in Clostridioides difficile https://www.biorxiv.org/content/10.1101/2025.07.24.666506v1
July 26, 2025 at 3:08 AM
Excited to share this collaborative study with @ritatamayo.bsky.social showing that E. faecalis influences C. diff morphology through the phase variable CmrRST system! This work was co-led by the amazing team of @ashleyweiss.bsky.social and Jilarie Santos-Santiago!
Reposted by Christin Herrmann
Congratulations @christinviral.bsky.social and team for publishing this super cool discovery 😎 www.nature.com/articles/s41.... Here’s a quick summary of our cool findings about how stress due to simple mouse husbandry drives clearance of persistent enteric viral infection 🦠🐭 1/5
Environmental stress drives clearance of a persistent enteric virus in mice - Nature Microbiology
Cage change of mice with persistent murine astrovirus infection triggers stress responses marked by corticosterone fluctuation, which is followed by CD8 T cell activation and induction of epithelial a...
www.nature.com
June 27, 2025 at 12:23 AM
Congratulations @christinviral.bsky.social and team for publishing this super cool discovery 😎 www.nature.com/articles/s41.... Here’s a quick summary of our cool findings about how stress due to simple mouse husbandry drives clearance of persistent enteric viral infection 🦠🐭 1/5
Reposted by Christin Herrmann
#NewResearch
🚨Out now!
Environmental stress drives clearance of a persistent enteric virus in mice 🐀
@christinviral.bsky.social @cadwelllab.bsky.social
#MicroSky #VirusSky
www.nature.com/articles/s41...
🚨Out now!
Environmental stress drives clearance of a persistent enteric virus in mice 🐀
@christinviral.bsky.social @cadwelllab.bsky.social
#MicroSky #VirusSky
www.nature.com/articles/s41...
Environmental stress drives clearance of a persistent enteric virus in mice - Nature Microbiology
Cage change of mice with persistent murine astrovirus infection triggers stress responses marked by corticosterone fluctuation, which is followed by CD8 T cell activation and induction of epithelial a...
www.nature.com
June 25, 2025 at 2:37 PM
#NewResearch
🚨Out now!
Environmental stress drives clearance of a persistent enteric virus in mice 🐀
@christinviral.bsky.social @cadwelllab.bsky.social
#MicroSky #VirusSky
www.nature.com/articles/s41...
🚨Out now!
Environmental stress drives clearance of a persistent enteric virus in mice 🐀
@christinviral.bsky.social @cadwelllab.bsky.social
#MicroSky #VirusSky
www.nature.com/articles/s41...
Excited to share with you my postdoctoral work published today in Nature Microbiology!
www.nature.com/articles/s41...
We have known for a while that stress can impact the outcome of infectious diseases; however, we reveal in our paper that it is not always detrimental.
www.nature.com/articles/s41...
We have known for a while that stress can impact the outcome of infectious diseases; however, we reveal in our paper that it is not always detrimental.
Environmental stress drives clearance of a persistent enteric virus in mice - Nature Microbiology
Cage change of mice with persistent murine astrovirus infection triggers stress responses marked by corticosterone fluctuation, which is followed by CD8 T cell activation and induction of epithelial a...
www.nature.com
June 25, 2025 at 11:55 AM
Excited to share with you my postdoctoral work published today in Nature Microbiology!
www.nature.com/articles/s41...
We have known for a while that stress can impact the outcome of infectious diseases; however, we reveal in our paper that it is not always detrimental.
www.nature.com/articles/s41...
We have known for a while that stress can impact the outcome of infectious diseases; however, we reveal in our paper that it is not always detrimental.
Reposted by Christin Herrmann
Thrilled that our latest paper showing that DCs undergo either pyroptosis or apoptosis upon bacterial blockade of host translation to restrict Legionella is now online at the @asm.org journal mBio! Congrats to 1st author @vvazquez.bsky.social & co-authors! 🎉 journals.asm.org/doi/10.1128/...
Dendritic cells activate pyroptosis and effector-triggered apoptosis to restrict Legionella infection | mBio
The innate immune system senses bacterial pathogens by employing pattern recognition
receptors that detect pathogen-associated molecular patterns (PAMPs) and guard proteins
that monitor pathogen disru...
journals.asm.org
June 19, 2025 at 3:40 PM
Thrilled that our latest paper showing that DCs undergo either pyroptosis or apoptosis upon bacterial blockade of host translation to restrict Legionella is now online at the @asm.org journal mBio! Congrats to 1st author @vvazquez.bsky.social & co-authors! 🎉 journals.asm.org/doi/10.1128/...
Reposted by Christin Herrmann
Incredibly honored to be selected as a @bwfund.bsky.social Investigator in the Pathogenesis of Infectious Disease. Thank you to @bwfund.bsky.social for supporting our work - I am thrilled to join this amazing community! And special thank you to my AMAZING team (past & present) for getting us here!
Announcing the 2025 Investigators in the Pathogenesis of Infectious Disease www.bwfund.org/news/announc... #bwfpath
Announcing the 2025 Investigators in the Pathogenesis of Infectious Disease - Burroughs Wellcome Fund
DURHAM, N.C. – The Burroughs Wellcome Fund proudly announces the 2025 Investigators in the Pathogenesis of Infectious Disease (PATH) award recipients. This year’s cohort represents a diverse group of…
www.bwfund.org
May 23, 2025 at 5:22 PM
Incredibly honored to be selected as a @bwfund.bsky.social Investigator in the Pathogenesis of Infectious Disease. Thank you to @bwfund.bsky.social for supporting our work - I am thrilled to join this amazing community! And special thank you to my AMAZING team (past & present) for getting us here!
Reposted by Christin Herrmann
Congratulations Xiaomin Yao and Eugene Rudensky for publishing this story @cp-immunity.bsky.social! Big thank you to NIH for making this work possible. Here’s a brief summary of this 🤯 finding about a gene variant that YOU 🫵 most likely have 1/n
kwnsfk27.r.eu-west-1.awstrack.me
May 17, 2025 at 10:25 PM
Congratulations Xiaomin Yao and Eugene Rudensky for publishing this story @cp-immunity.bsky.social! Big thank you to NIH for making this work possible. Here’s a brief summary of this 🤯 finding about a gene variant that YOU 🫵 most likely have 1/n
Reposted by Christin Herrmann
Excited to share our new work in @aga-gastro.bsky.social! We show that dietary fiber alters the window of susceptibility to C. difficile following antibiotic exposure. This really fantastic study was co-led by an amazing team @rinniehewlett.bsky.social @alhecht.bsky.social and Amanda PeBenito.
Dietary fiber modulates the window of susceptibility to Clostridioides difficile infection
Clostridioides difficile epidemiology is rapidly evolving, and understanding the factors
that contribute to one’s risk of C. difficile infection (CDI) is urgently needed.
Based on our observations in ...
www.gastrojournal.org
May 16, 2025 at 9:20 PM
Excited to share our new work in @aga-gastro.bsky.social! We show that dietary fiber alters the window of susceptibility to C. difficile following antibiotic exposure. This really fantastic study was co-led by an amazing team @rinniehewlett.bsky.social @alhecht.bsky.social and Amanda PeBenito.
Reposted by Christin Herrmann
1/3 It’s official 🙌🏽
The Reyes Ruiz Lab is opening in 2026 at the University of Wisconsin, Madison in the Department of Pathobiological Sciences. My lab will focus on host antibacterial effectors and adaptation of bacteria to host-imposed stress during S. aureus infections.
The Reyes Ruiz Lab is opening in 2026 at the University of Wisconsin, Madison in the Department of Pathobiological Sciences. My lab will focus on host antibacterial effectors and adaptation of bacteria to host-imposed stress during S. aureus infections.
May 14, 2025 at 3:40 AM
1/3 It’s official 🙌🏽
The Reyes Ruiz Lab is opening in 2026 at the University of Wisconsin, Madison in the Department of Pathobiological Sciences. My lab will focus on host antibacterial effectors and adaptation of bacteria to host-imposed stress during S. aureus infections.
The Reyes Ruiz Lab is opening in 2026 at the University of Wisconsin, Madison in the Department of Pathobiological Sciences. My lab will focus on host antibacterial effectors and adaptation of bacteria to host-imposed stress during S. aureus infections.
Reposted by Christin Herrmann
Excited to share our latest study
@cp-immunity.bsky.social. Heartfelt thanks to the editorial and review teams , to my co-first @yeungadventures.bsky.social, our co-authors, and to @khannakm.bsky.social
for his outstanding mentorship throughout! Pls read/share!👇
www.cell.com/immunity/ful...
@cp-immunity.bsky.social. Heartfelt thanks to the editorial and review teams , to my co-first @yeungadventures.bsky.social, our co-authors, and to @khannakm.bsky.social
for his outstanding mentorship throughout! Pls read/share!👇
www.cell.com/immunity/ful...
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung
infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential
role of nerve- and airway-associated...
www.cell.com
April 25, 2025 at 2:38 PM
Excited to share our latest study
@cp-immunity.bsky.social. Heartfelt thanks to the editorial and review teams , to my co-first @yeungadventures.bsky.social, our co-authors, and to @khannakm.bsky.social
for his outstanding mentorship throughout! Pls read/share!👇
www.cell.com/immunity/ful...
@cp-immunity.bsky.social. Heartfelt thanks to the editorial and review teams , to my co-first @yeungadventures.bsky.social, our co-authors, and to @khannakm.bsky.social
for his outstanding mentorship throughout! Pls read/share!👇
www.cell.com/immunity/ful...
Reposted by Christin Herrmann
Our lab has opened at the Cancer Biology Department and the Basser Center for BRCA @upenn.bsky.social! We study new mechanisms of hereditary cancers and their implications for sporadic cancers, building on my training with @labjacks.bsky.social and Joan Brugge.
Join us! tinyurl.com/CarmanLiLabH...
Join us! tinyurl.com/CarmanLiLabH...
Carman Li Lab
www.CarmanLiLab.org
April 20, 2025 at 3:38 AM
Our lab has opened at the Cancer Biology Department and the Basser Center for BRCA @upenn.bsky.social! We study new mechanisms of hereditary cancers and their implications for sporadic cancers, building on my training with @labjacks.bsky.social and Joan Brugge.
Join us! tinyurl.com/CarmanLiLabH...
Join us! tinyurl.com/CarmanLiLabH...
Reposted by Christin Herrmann
Gastrointestinal colonization as a source of Staphylococcus aureus in atopic dermatitis https://www.biorxiv.org/content/10.1101/2025.04.17.648849v1
April 18, 2025 at 6:16 AM
Gastrointestinal colonization as a source of Staphylococcus aureus in atopic dermatitis https://www.biorxiv.org/content/10.1101/2025.04.17.648849v1
Reposted by Christin Herrmann
After 8 months of peer review, our manuscript was published today @nature.com showing that bovine H5N1 viruses bind poorly to human-type sialic acid receptors. We now know that the virus is only 1 HA substitution away from efficiently binding human receptors.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Bovine H5N1 binds poorly to human-type sialic acid receptors - Nature
Nature - Bovine H5N1 binds poorly to human-type sialic acid receptors
www.nature.com
April 16, 2025 at 6:40 PM
After 8 months of peer review, our manuscript was published today @nature.com showing that bovine H5N1 viruses bind poorly to human-type sialic acid receptors. We now know that the virus is only 1 HA substitution away from efficiently binding human receptors.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Christin Herrmann
Proud of this work, led by the amazing Jeannette Tenthorey (now Assistant Professor at UCSF), demonstrating the adaptive power of single indel mutations in host-virus arms races, but a little sad that this is the coda to her amazing postdoc in the Malik & Emerman labs.
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations
Tenthorey et al. compare the effects of missense and indel mutations on the acquisition
of functional novelty by the rapidly evolving antiviral protein TRIM5α. They find
that single indel mutations al...
www.cell.com
March 27, 2025 at 9:36 PM
Proud of this work, led by the amazing Jeannette Tenthorey (now Assistant Professor at UCSF), demonstrating the adaptive power of single indel mutations in host-virus arms races, but a little sad that this is the coda to her amazing postdoc in the Malik & Emerman labs.
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Reposted by Christin Herrmann
In 2024 NIH grant awards supported 407,782 jobs and $94.58 billion in new economic activity nationwide, the largest figure in the history of the report. www.forbes.com/sites/michae...
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
www.forbes.com
March 13, 2025 at 12:55 AM
In 2024 NIH grant awards supported 407,782 jobs and $94.58 billion in new economic activity nationwide, the largest figure in the history of the report. www.forbes.com/sites/michae...
Reposted by Christin Herrmann
As federal funding for research is uncertain, we need to diversify funding sources for our PhD students.
Here is a comprehensive list of >160 PhD fellowships and funding opportunities, mostly from private foundations and scientific societies.
Download it here: research.jhu.edu/rdt/funding-...
Here is a comprehensive list of >160 PhD fellowships and funding opportunities, mostly from private foundations and scientific societies.
Download it here: research.jhu.edu/rdt/funding-...
March 9, 2025 at 9:15 PM
As federal funding for research is uncertain, we need to diversify funding sources for our PhD students.
Here is a comprehensive list of >160 PhD fellowships and funding opportunities, mostly from private foundations and scientific societies.
Download it here: research.jhu.edu/rdt/funding-...
Here is a comprehensive list of >160 PhD fellowships and funding opportunities, mostly from private foundations and scientific societies.
Download it here: research.jhu.edu/rdt/funding-...
Reposted by Christin Herrmann
Congratulations Ying-Han Chen and Kim Zaldana for showing how B cells are altered when lab mice 🐭 are released outdoors! www.science.org/doi/10.1126/...
Here’s some context for the paper followed by how gov’t 💰 + other sources combine to make these types of studies possible 1/n
Here’s some context for the paper followed by how gov’t 💰 + other sources combine to make these types of studies possible 1/n
Rewilding catalyzes maturation of the humoral immune system
Releasing laboratory mice into the natural environment enhanced maturation and activation of the humoral immune system.
www.science.org
March 8, 2025 at 2:40 PM
Congratulations Ying-Han Chen and Kim Zaldana for showing how B cells are altered when lab mice 🐭 are released outdoors! www.science.org/doi/10.1126/...
Here’s some context for the paper followed by how gov’t 💰 + other sources combine to make these types of studies possible 1/n
Here’s some context for the paper followed by how gov’t 💰 + other sources combine to make these types of studies possible 1/n
Reposted by Christin Herrmann
In the US alone, each year, norovirus causes ~20 million acute gastroenteritis cases, 70,000 hospitalizations, up to 800 deaths, at a cost of ~$10.6 billion annually.
An pill vaccine shows considerable promise in a clinical trial, establishing mucosal immunity
www.science.org/doi/10.1126/...
An pill vaccine shows considerable promise in a clinical trial, establishing mucosal immunity
www.science.org/doi/10.1126/...
An oral norovirus vaccine tablet was safe and elicited mucosal immunity in older adults in a phase 1b clinical trial
An oral norovirus vaccine tablet is safe and induces strong mucosal and systemic immune responses in adults aged 55 to 80 years.
www.science.org
March 6, 2025 at 12:02 AM
In the US alone, each year, norovirus causes ~20 million acute gastroenteritis cases, 70,000 hospitalizations, up to 800 deaths, at a cost of ~$10.6 billion annually.
An pill vaccine shows considerable promise in a clinical trial, establishing mucosal immunity
www.science.org/doi/10.1126/...
An pill vaccine shows considerable promise in a clinical trial, establishing mucosal immunity
www.science.org/doi/10.1126/...
Reposted by Christin Herrmann
March 2, 2025 at 4:07 PM
Reposted by Christin Herrmann
Excited to share our work with @pjplanet.bsky.social and @ahmedmicrobes.bsky.social tracking Staph aureus transmission across the NICU using genomics!!
This study was co-led by the amazing @qianxuan.bsky.social and Lakshmi Srinivasan, and made possible by the @centermicrobialmed.bsky.social
This study was co-led by the amazing @qianxuan.bsky.social and Lakshmi Srinivasan, and made possible by the @centermicrobialmed.bsky.social
Transmission of Staphylococcus aureus in the neonatal intensive care unit predicts invasive infection
Background Staphylococcus aureus is a leading cause of healthcare-associated infection and is one of the most common pathogens causing serious invasive infection in the neonatal intensive care unit (N...
www.medrxiv.org
March 1, 2025 at 1:21 PM
Excited to share our work with @pjplanet.bsky.social and @ahmedmicrobes.bsky.social tracking Staph aureus transmission across the NICU using genomics!!
This study was co-led by the amazing @qianxuan.bsky.social and Lakshmi Srinivasan, and made possible by the @centermicrobialmed.bsky.social
This study was co-led by the amazing @qianxuan.bsky.social and Lakshmi Srinivasan, and made possible by the @centermicrobialmed.bsky.social
Reposted by Christin Herrmann
Once upon a time, some villagers came across a large, ornate wooden box in the local woods. On the side of the box was a message:
“Whatever money you put in this box will, in future, grow to become 2.5 times larger.”
1/
“Whatever money you put in this box will, in future, grow to become 2.5 times larger.”
1/
February 23, 2025 at 10:11 AM
Once upon a time, some villagers came across a large, ornate wooden box in the local woods. On the side of the box was a message:
“Whatever money you put in this box will, in future, grow to become 2.5 times larger.”
1/
“Whatever money you put in this box will, in future, grow to become 2.5 times larger.”
1/
Reposted by Christin Herrmann
1/2 New publication from the lab from the talented postdoc Dr. Andy Perrault in collaboration with Dr. Alejandro Pironti! pubmed.ncbi.nlm.nih.gov/39977318/
Enterobacter hormaechei replaces virulence with carbapenem resistance via porin loss - PubMed
Pathogenic <i>Enterobacter</i> species are of increasing clinical concern due to the multidrug-resistant nature of these bacteria, including resistance to carbapenem antibiotics. Our understanding of ...
pubmed.ncbi.nlm.nih.gov
February 22, 2025 at 3:42 PM
1/2 New publication from the lab from the talented postdoc Dr. Andy Perrault in collaboration with Dr. Alejandro Pironti! pubmed.ncbi.nlm.nih.gov/39977318/
Reposted by Christin Herrmann
Excited to share our latest preprint! We find that DCs undergo heterogeneous cell death- either pyroptosis or apoptosis upon bacterial blockade of host translation- to restrict Legionella infection. Congrats to my PhD student @vvazquez.bsky.social & co-authors! Check out his bluetorial 🧵 below! 👇
Bluesky post
I’m very excited to share a preprint of the bulk of my thesis work in @sunnyshinlab.bsky.social where we investigate how dendritic cells respond to Legionella pneumophila
www.biorxiv.org/content/10.1...
I’m very excited to share a preprint of the bulk of my thesis work in @sunnyshinlab.bsky.social where we investigate how dendritic cells respond to Legionella pneumophila
www.biorxiv.org/content/10.1...
Dendritic cells activate pyroptosis and effector-triggered apoptosis to restrict Legionella infection
The innate immune system relies on pattern recognition receptors (PRRs) to detect pathogen-associated molecular patterns (PAMPs) and guard proteins to monitor pathogen disruption of host cell processe...
www.biorxiv.org
February 21, 2025 at 6:43 PM
Excited to share our latest preprint! We find that DCs undergo heterogeneous cell death- either pyroptosis or apoptosis upon bacterial blockade of host translation- to restrict Legionella infection. Congrats to my PhD student @vvazquez.bsky.social & co-authors! Check out his bluetorial 🧵 below! 👇