Manfred Jung
@chemepi.bsky.social
Medicinal Chemist, Prof. @uni-freiburg.de, Chemical Epigenetics www.jungm.de
Hobby Chef #ChemistsWhoCook
Hobby Chef #ChemistsWhoCook
Pinned
Manfred Jung
@chemepi.bsky.social
· Nov 22
Wow, #bluesky grows fast. In a few days from around 150 to over 1000 followers, thanks for stopping by. Short introduction: heading an academic MedChem/ChemBio lab @UniFreiburg, biotech spinout in drug discovery against therapy resistent prostate cancer; Hobby chef #ChemistsWhoCook
Reposted by Manfred Jung
You might know 1,2,3-triazoles as stable linkers in medicinal chemistry. Have a look on a twist on triazoles in our latest publication in #AngewandteChemie
We report a new class of 1,2,3-triazole sirtuin inhibitors that
display unexpected reactivity with formation of an ADP adduct from NAD+ 1/
We report a new class of 1,2,3-triazole sirtuin inhibitors that
display unexpected reactivity with formation of an ADP adduct from NAD+ 1/
November 2, 2025 at 1:17 PM
You might know 1,2,3-triazoles as stable linkers in medicinal chemistry. Have a look on a twist on triazoles in our latest publication in #AngewandteChemie
We report a new class of 1,2,3-triazole sirtuin inhibitors that
display unexpected reactivity with formation of an ADP adduct from NAD+ 1/
We report a new class of 1,2,3-triazole sirtuin inhibitors that
display unexpected reactivity with formation of an ADP adduct from NAD+ 1/
Boah, Stuttgart Hauptbahnhof nervt mal wieder . Zu 3 verschiedenen Gleisen nacheinander für die Katz... (Panda)
a panda bear is standing next to an orange car .
ALT: a panda bear is standing next to an orange car .
media.tenor.com
October 30, 2025 at 10:01 PM
Boah, Stuttgart Hauptbahnhof nervt mal wieder . Zu 3 verschiedenen Gleisen nacheinander für die Katz... (Panda)
Reposted by Manfred Jung
We are looking for a PhD candidate for an exciting project in chemical biology and microbiology.
Please apply through the below link if you want to pursue new anti-virulence strategies to target antibiotic-resistant bacteria.
jobportal.ku.dk/phd/?show=15...
Please apply through the below link if you want to pursue new anti-virulence strategies to target antibiotic-resistant bacteria.
jobportal.ku.dk/phd/?show=15...
PhD fellowship in Chemical Biology at Department of Drug Design and Pharmacology
jobportal.ku.dk
October 30, 2025 at 11:22 AM
We are looking for a PhD candidate for an exciting project in chemical biology and microbiology.
Please apply through the below link if you want to pursue new anti-virulence strategies to target antibiotic-resistant bacteria.
jobportal.ku.dk/phd/?show=15...
Please apply through the below link if you want to pursue new anti-virulence strategies to target antibiotic-resistant bacteria.
jobportal.ku.dk/phd/?show=15...
Reposted by Manfred Jung
40 Percent of Stroke Animal Studies May Have Problematic Images
Red flags during a literature review led to the discovery of over 200 papers on animal models of stroke with duplicated images, which is likely an underestimate.
www.the-scientist.com/40-percent-o...
Red flags during a literature review led to the discovery of over 200 papers on animal models of stroke with duplicated images, which is likely an underestimate.
www.the-scientist.com/40-percent-o...
40 Percent of Stroke Animal Studies May Have Problematic Images
Red flags during a literature review led to the discovery of over 200 papers on animal models of stroke with duplicated images, which is likely an underestimate.
www.the-scientist.com
October 30, 2025 at 6:39 PM
40 Percent of Stroke Animal Studies May Have Problematic Images
Red flags during a literature review led to the discovery of over 200 papers on animal models of stroke with duplicated images, which is likely an underestimate.
www.the-scientist.com/40-percent-o...
Red flags during a literature review led to the discovery of over 200 papers on animal models of stroke with duplicated images, which is likely an underestimate.
www.the-scientist.com/40-percent-o...
Fate (or ChatGPT) picked me as the person to open the first door of the group Adventskalender 😊 (see whole picture)
October 27, 2025 at 12:11 PM
Fate (or ChatGPT) picked me as the person to open the first door of the group Adventskalender 😊 (see whole picture)
Linguine, salad pesto, fried shrimp #ChemistsWhoCook
October 25, 2025 at 8:58 AM
Linguine, salad pesto, fried shrimp #ChemistsWhoCook
Horror Story with happy Ending in 5 words: Kassel Wilhelmshöhe ... aber kein Umstieg
October 23, 2025 at 2:44 PM
Horror Story with happy Ending in 5 words: Kassel Wilhelmshöhe ... aber kein Umstieg
Mum's recipe: Krautkopf. The mold is probably about my age 😃 #ChemistsWhoCook
October 17, 2025 at 7:03 PM
Mum's recipe: Krautkopf. The mold is probably about my age 😃 #ChemistsWhoCook
Prime exemple of violating the house rules is... if you violate the house rules
October 11, 2025 at 11:40 AM
Prime exemple of violating the house rules is... if you violate the house rules
Foam of smoked trout, creme fraiche, cream, mustard, wine, vermouth. #ChemistsWhoCook
October 4, 2025 at 6:02 PM
Foam of smoked trout, creme fraiche, cream, mustard, wine, vermouth. #ChemistsWhoCook
Charcuterie, with quince chutney #ChemistsWhoCook
October 3, 2025 at 6:26 PM
Charcuterie, with quince chutney #ChemistsWhoCook
I feel you, little tomato
September 26, 2025 at 4:12 PM
I feel you, little tomato
The basis for our current ANR-DFG project with Gerald Späth: Leishmania manipulate host macrophage epigenetics, via histone demethylase LSD1. @agencerecherche.bsky.social @dfg.de @pasteur.fr #epigenetics @biorxiv-neursci.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Inhibition of the macrophage demethylase LSD1 reverses Leishmania amazonensis-induced transcriptomic changes and causes a decrease in parasite load
Intracellular pathogens exploit host cell functions to favor their own survival. In recent years, the subversion of epigenetic regulation has emerged as a key microbial strategy to modify host cell ge...
www.biorxiv.org
September 26, 2025 at 7:54 AM
The basis for our current ANR-DFG project with Gerald Späth: Leishmania manipulate host macrophage epigenetics, via histone demethylase LSD1. @agencerecherche.bsky.social @dfg.de @pasteur.fr #epigenetics @biorxiv-neursci.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Manfred Jung
Können wir uns Budgetkürzungen in den Geisteswissenschaften leisten?
@amreibahr.bsky.social verneint klar: Diese seien aktuell sogar wichtiger denn je, weil sie die Demokratie schützten. Mehr zum Thema im @deutschlandfunk.de.web.brid.gy: www.deutschlandfunk.de/wie-viele-ku... #Wissverständnis
@amreibahr.bsky.social verneint klar: Diese seien aktuell sogar wichtiger denn je, weil sie die Demokratie schützten. Mehr zum Thema im @deutschlandfunk.de.web.brid.gy: www.deutschlandfunk.de/wie-viele-ku... #Wissverständnis
September 22, 2025 at 12:35 PM
Können wir uns Budgetkürzungen in den Geisteswissenschaften leisten?
@amreibahr.bsky.social verneint klar: Diese seien aktuell sogar wichtiger denn je, weil sie die Demokratie schützten. Mehr zum Thema im @deutschlandfunk.de.web.brid.gy: www.deutschlandfunk.de/wie-viele-ku... #Wissverständnis
@amreibahr.bsky.social verneint klar: Diese seien aktuell sogar wichtiger denn je, weil sie die Demokratie schützten. Mehr zum Thema im @deutschlandfunk.de.web.brid.gy: www.deutschlandfunk.de/wie-viele-ku... #Wissverständnis
Reposted by Manfred Jung
The future of @cibss.bsky.social @uni-freiburg.de is about teamwork, curiosity, and collaboration across disciplines.
We are thrilled to be in this together @kraftlabfr.bsky.social @archaellum.bsky.social @kleinevehnlab.bsky.social !
We are thrilled to be in this together @kraftlabfr.bsky.social @archaellum.bsky.social @kleinevehnlab.bsky.social !
September 22, 2025 at 2:40 PM
The future of @cibss.bsky.social @uni-freiburg.de is about teamwork, curiosity, and collaboration across disciplines.
We are thrilled to be in this together @kraftlabfr.bsky.social @archaellum.bsky.social @kleinevehnlab.bsky.social !
We are thrilled to be in this together @kraftlabfr.bsky.social @archaellum.bsky.social @kleinevehnlab.bsky.social !
Reposted by Manfred Jung
New leadership for #CIBSS!
Welcome Sonja-Verena Albers as new spokesperson & congrats to Claudine Kraft on her confirmation. Together with Jürgen Kleine-Vehn, they’ll lead CIBSS into its #NextChapter – following Wolfgang Driever & Carola Hunte.
More info: kurzlinks.de/fkv4
Welcome Sonja-Verena Albers as new spokesperson & congrats to Claudine Kraft on her confirmation. Together with Jürgen Kleine-Vehn, they’ll lead CIBSS into its #NextChapter – following Wolfgang Driever & Carola Hunte.
More info: kurzlinks.de/fkv4
September 22, 2025 at 10:01 AM
New leadership for #CIBSS!
Welcome Sonja-Verena Albers as new spokesperson & congrats to Claudine Kraft on her confirmation. Together with Jürgen Kleine-Vehn, they’ll lead CIBSS into its #NextChapter – following Wolfgang Driever & Carola Hunte.
More info: kurzlinks.de/fkv4
Welcome Sonja-Verena Albers as new spokesperson & congrats to Claudine Kraft on her confirmation. Together with Jürgen Kleine-Vehn, they’ll lead CIBSS into its #NextChapter – following Wolfgang Driever & Carola Hunte.
More info: kurzlinks.de/fkv4
Reposted by Manfred Jung
Unhelpful framing. Scientists know we always need to be improving what we do, but science is not “broken”. To suggest this justifies the misplaced destruction of US scientific institutions.
@nytimes.com
@nytimes.com
September 22, 2025 at 11:15 AM
Unhelpful framing. Scientists know we always need to be improving what we do, but science is not “broken”. To suggest this justifies the misplaced destruction of US scientific institutions.
@nytimes.com
@nytimes.com
Oh, the spanish town of Gießen 😃
Celavi Giessen – Tapas Bar celavi-giessen.de
Celavi Giessen – Tapas Bar celavi-giessen.de
September 21, 2025 at 12:31 PM
Oh, the spanish town of Gießen 😃
Celavi Giessen – Tapas Bar celavi-giessen.de
Celavi Giessen – Tapas Bar celavi-giessen.de
Did not win in the cow poop Bingo... (had 4 tickets) but some of the money goes to charity, so a win after all
September 21, 2025 at 12:04 PM
Did not win in the cow poop Bingo... (had 4 tickets) but some of the money goes to charity, so a win after all
Reposted by Manfred Jung
📻 Wie viele Kürzungen an den Hochschulen können wir uns leisten? — Hallo aus Dortmund! Hier geht‘s für mich später ins Studio, um genau darüber ab 14.05 Uhr in der Livesendung von Campus & Karriere im DLF zu diskutieren. Ihr könnt zuhören & mitdiskutieren! Hörer_innen-☎️: 00800-4464 4464
#IchBinHanna
#IchBinHanna
September 20, 2025 at 9:28 AM
📻 Wie viele Kürzungen an den Hochschulen können wir uns leisten? — Hallo aus Dortmund! Hier geht‘s für mich später ins Studio, um genau darüber ab 14.05 Uhr in der Livesendung von Campus & Karriere im DLF zu diskutieren. Ihr könnt zuhören & mitdiskutieren! Hörer_innen-☎️: 00800-4464 4464
#IchBinHanna
#IchBinHanna
Defekter Stromabnehmer im Zug. Auf Strecke liegen geblieben. Klimaanlage ausgefallen. "Der Notfallmanager muss kommen, das kann dauern..." (ein Mitarbeiter zum anderen)
a young boy is laughing with his mouth open in a striped shirt .
ALT: a young boy is laughing with his mouth open in a striped shirt .
media.tenor.com
September 18, 2025 at 5:48 PM
Defekter Stromabnehmer im Zug. Auf Strecke liegen geblieben. Klimaanlage ausgefallen. "Der Notfallmanager muss kommen, das kann dauern..." (ein Mitarbeiter zum anderen)
Reposted by Manfred Jung
Immer mehr und mehr 6-Methylnikotin-haltige Produkte wurden seit 2023 auf den Markt geworfen, auch in Europa und Asien.
September 6, 2025 at 2:11 AM
Immer mehr und mehr 6-Methylnikotin-haltige Produkte wurden seit 2023 auf den Markt geworfen, auch in Europa und Asien.