Christian A. Olsen
@christianaolsen.bsky.social
Professor
Drug Design and Pharmacology
University of Copenhagen
Drug Design and Pharmacology
University of Copenhagen
We are looking for a PhD candidate for an exciting project in chemical biology and microbiology.
Please apply through the below link if you want to pursue new anti-virulence strategies to target antibiotic-resistant bacteria.
jobportal.ku.dk/phd/?show=15...
Please apply through the below link if you want to pursue new anti-virulence strategies to target antibiotic-resistant bacteria.
jobportal.ku.dk/phd/?show=15...
PhD fellowship in Chemical Biology at Department of Drug Design and Pharmacology
jobportal.ku.dk
October 30, 2025 at 11:22 AM
We are looking for a PhD candidate for an exciting project in chemical biology and microbiology.
Please apply through the below link if you want to pursue new anti-virulence strategies to target antibiotic-resistant bacteria.
jobportal.ku.dk/phd/?show=15...
Please apply through the below link if you want to pursue new anti-virulence strategies to target antibiotic-resistant bacteria.
jobportal.ku.dk/phd/?show=15...
Check out the write-up of our new publication in #mBio, where we profiled a large number auto-inducing peptide (AIP) signaling molecules from staphylococci.
@ucph.bsky.social @bgless.bsky.social @benjaminsb.bsky.social
news.ku.dk/all_news/202...
@ucph.bsky.social @bgless.bsky.social @benjaminsb.bsky.social
news.ku.dk/all_news/202...
Bacteria from cows show promising results in treating MRSA infections
New research from the University of Copenhagen shows that signaling molecules from a specific Staphylococcus bacterium can treat MRSA infections as effectively as antibiotics.
news.ku.dk
July 17, 2025 at 9:13 AM
Check out the write-up of our new publication in #mBio, where we profiled a large number auto-inducing peptide (AIP) signaling molecules from staphylococci.
@ucph.bsky.social @bgless.bsky.social @benjaminsb.bsky.social
news.ku.dk/all_news/202...
@ucph.bsky.social @bgless.bsky.social @benjaminsb.bsky.social
news.ku.dk/all_news/202...
The final version of this publication is now online: journals.asm.org/doi/epdf/10....
July 17, 2025 at 9:04 AM
The final version of this publication is now online: journals.asm.org/doi/epdf/10....
We are hiring at the Department of Drug Design and Pharmacology.
Check out these opportunities and consider becoming our new colleague at University of Copenhagen.
employment.ku.dk/faculty/?sho...
Check out these opportunities and consider becoming our new colleague at University of Copenhagen.
employment.ku.dk/faculty/?sho...
164291 Associate Professor or Professor
employment.ku.dk
July 8, 2025 at 12:52 PM
We are hiring at the Department of Drug Design and Pharmacology.
Check out these opportunities and consider becoming our new colleague at University of Copenhagen.
employment.ku.dk/faculty/?sho...
Check out these opportunities and consider becoming our new colleague at University of Copenhagen.
employment.ku.dk/faculty/?sho...
Reposted by Christian A. Olsen
Our latest paper on the sodium leak channel NALCN complex is now online. We found that the neuronal SNARE proteins syntaxin 1A and SNAP25 inhibit sodium leak currents both in heterologous systems and in neurons!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
March 14, 2025 at 7:49 PM
Our latest paper on the sodium leak channel NALCN complex is now online. We found that the neuronal SNARE proteins syntaxin 1A and SNAP25 inhibit sodium leak currents both in heterologous systems and in neurons!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Christian A. Olsen
Chemical Solutions to Structural Biology symposium.
Registration and abstract submission now open:
isbuc.ku.dk/chemical-sol...
Registration and abstract submission now open:
isbuc.ku.dk/chemical-sol...
February 12, 2025 at 10:38 AM
Chemical Solutions to Structural Biology symposium.
Registration and abstract submission now open:
isbuc.ku.dk/chemical-sol...
Registration and abstract submission now open:
isbuc.ku.dk/chemical-sol...
Check out the final version of this paper. Now out in #JACS_Au @pubs.acs.org
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
February 16, 2025 at 5:14 PM
Check out the final version of this paper. Now out in #JACS_Au @pubs.acs.org
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Congratulations @carlosmyruela.bsky.social, @beatfierz.bsky.social and team on a great and important publication, providing new insights into SIRT7 activity
#SIRT7 is a histone deacetylase with highly specific activity on #chromatin substrates.
We just published mechanism-based #cryoEM structures of #SIRT7 on nucleosomes to understand its activity 👇
www.nature.com/articles/s41...
(1/8) #ChemBio #ChemSky
We just published mechanism-based #cryoEM structures of #SIRT7 on nucleosomes to understand its activity 👇
www.nature.com/articles/s41...
(1/8) #ChemBio #ChemSky
February 4, 2025 at 7:12 PM
Congratulations @carlosmyruela.bsky.social, @beatfierz.bsky.social and team on a great and important publication, providing new insights into SIRT7 activity
I am extremely happy to share this new @biorxivpreprint.bsky.social, which after a long wait updates our previous preprint.
Thanks to main drivers @bgless.bsky.social and @benjaminsb.bsky.social as well as all involved colleagues and collaborators!
www.biorxiv.org/content/10.1...
Thanks to main drivers @bgless.bsky.social and @benjaminsb.bsky.social as well as all involved colleagues and collaborators!
www.biorxiv.org/content/10.1...
January 31, 2025 at 9:58 AM
I am extremely happy to share this new @biorxivpreprint.bsky.social, which after a long wait updates our previous preprint.
Thanks to main drivers @bgless.bsky.social and @benjaminsb.bsky.social as well as all involved colleagues and collaborators!
www.biorxiv.org/content/10.1...
Thanks to main drivers @bgless.bsky.social and @benjaminsb.bsky.social as well as all involved colleagues and collaborators!
www.biorxiv.org/content/10.1...
I am grateful to @tnhansen.bsky.social, #Annika-Mergel, and #Marcos-San-Segundo for co-authoring this piece!
@ucph.bsky.social
@ucph.bsky.social
We have a new review article on recent applications of SuFEx chemistry in chemical biology now on-line at #TrendsChem @cellpress.bsky.social
Thanks to @novo-nordisk.bsky.social for funding our work.
authors.elsevier.com/a/1kWpX9CpcY...
Previously on ChemRxiv:
chemrxiv.org/engage/chemr...
Thanks to @novo-nordisk.bsky.social for funding our work.
authors.elsevier.com/a/1kWpX9CpcY...
Previously on ChemRxiv:
chemrxiv.org/engage/chemr...
January 30, 2025 at 8:35 AM
I am grateful to @tnhansen.bsky.social, #Annika-Mergel, and #Marcos-San-Segundo for co-authoring this piece!
@ucph.bsky.social
@ucph.bsky.social
We have a new review article on recent applications of SuFEx chemistry in chemical biology now on-line at #TrendsChem @cellpress.bsky.social
Thanks to @novo-nordisk.bsky.social for funding our work.
authors.elsevier.com/a/1kWpX9CpcY...
Previously on ChemRxiv:
chemrxiv.org/engage/chemr...
Thanks to @novo-nordisk.bsky.social for funding our work.
authors.elsevier.com/a/1kWpX9CpcY...
Previously on ChemRxiv:
chemrxiv.org/engage/chemr...
January 30, 2025 at 8:31 AM
We have a new review article on recent applications of SuFEx chemistry in chemical biology now on-line at #TrendsChem @cellpress.bsky.social
Thanks to @novo-nordisk.bsky.social for funding our work.
authors.elsevier.com/a/1kWpX9CpcY...
Previously on ChemRxiv:
chemrxiv.org/engage/chemr...
Thanks to @novo-nordisk.bsky.social for funding our work.
authors.elsevier.com/a/1kWpX9CpcY...
Previously on ChemRxiv:
chemrxiv.org/engage/chemr...
Thank you #JACS-Au for the selection
'Peptide Backbone Cleavage and Transamidation via Thioester-to-Imide Acyl Transfer' from JACS Au is currently free to read as an #ACSEditorsChoice.
📖 Access the full article: https://buff.ly/3WtsCVu
📖 Access the full article: https://buff.ly/3WtsCVu
January 27, 2025 at 8:21 PM
Thank you #JACS-Au for the selection
We have an exciting PhD position available. In collaboration with researchers @scripps.edu, we will investigate bacterial communication within the gut microbiome for potential health benefits, using chemical tools.
Deadline 9 February, see 👇
candidate.hr-manager.net/ApplicationI...
Deadline 9 February, see 👇
candidate.hr-manager.net/ApplicationI...
PhD fellowship in Chemical Microbiology at Department of Drug Design and Pharmacology
Faculty of Health and Medical Sciences, University of Copenhagen We are offering a three-year PhD fellowship in Chemical Microbiology commencing 1 May 2025
candidate.hr-manager.net
January 21, 2025 at 7:34 AM
We have an exciting PhD position available. In collaboration with researchers @scripps.edu, we will investigate bacterial communication within the gut microbiome for potential health benefits, using chemical tools.
Deadline 9 February, see 👇
candidate.hr-manager.net/ApplicationI...
Deadline 9 February, see 👇
candidate.hr-manager.net/ApplicationI...
I am delighted to share that this paper is now published as an Editor's Choice article in JACS Au @pubs.acs.org
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
January 11, 2025 at 7:32 AM
I am delighted to share that this paper is now published as an Editor's Choice article in JACS Au @pubs.acs.org
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
I am very happy to share that we have received support from #Sygeforsikringen_danmark to investigate bacterial crosstalk within the gut microbiota together with #IngmerLab @ucph.bsky.social and #GhadiriLab @scripps.edu
sundhedsdonationer.dk/projekter/ba...
sundhedsdonationer.dk/projekter/ba...
Bakterielle signalmolekyler til brug for øget tarmsundhed - Sundhedsdonationer
sundhedsdonationer.dk
December 19, 2024 at 9:05 AM
I am very happy to share that we have received support from #Sygeforsikringen_danmark to investigate bacterial crosstalk within the gut microbiota together with #IngmerLab @ucph.bsky.social and #GhadiriLab @scripps.edu
sundhedsdonationer.dk/projekter/ba...
sundhedsdonationer.dk/projekter/ba...
New preprint @chemrxiv.bsky.social on discovery of macrocyclic inhibitors of HDAC11 with the Christian Heinis #EPFL
Main contributors @danieladankova.bsky.social, @alexanderln.bsky.social, @carlosmyruela.bsky.social
🙏 @ERC_Research, @novonordiskfond, @DFF_raad for 💶
chemrxiv.org/engage/chemr...
Main contributors @danieladankova.bsky.social, @alexanderln.bsky.social, @carlosmyruela.bsky.social
🙏 @ERC_Research, @novonordiskfond, @DFF_raad for 💶
chemrxiv.org/engage/chemr...
December 10, 2024 at 2:28 PM
New preprint @chemrxiv.bsky.social on discovery of macrocyclic inhibitors of HDAC11 with the Christian Heinis #EPFL
Main contributors @danieladankova.bsky.social, @alexanderln.bsky.social, @carlosmyruela.bsky.social
🙏 @ERC_Research, @novonordiskfond, @DFF_raad for 💶
chemrxiv.org/engage/chemr...
Main contributors @danieladankova.bsky.social, @alexanderln.bsky.social, @carlosmyruela.bsky.social
🙏 @ERC_Research, @novonordiskfond, @DFF_raad for 💶
chemrxiv.org/engage/chemr...
In a new preprint @chemrxiv.bsky.social, work from @bgless.bsky.social and Sabrina Schmied investigate the mechanism of a rearrangement that can lead to peptide/protein backbone cleavage.
Thanks to #LEOFondet for funding the project that led to this discovery.
chemrxiv.org/engage/chemr...
Thanks to #LEOFondet for funding the project that led to this discovery.
chemrxiv.org/engage/chemr...
Peptide Backbone Cleavage and trans-Amidation via Thioester-to-Imide Acyl Transfer
Cysteine thioesters are involved in a myriad of cen-tral biological transformations because of their unique reactivity. Despite their well-studied proper-ties, we discovered an unexpected trans-amidat...
chemrxiv.org
December 6, 2024 at 12:52 PM
In a new preprint @chemrxiv.bsky.social, work from @bgless.bsky.social and Sabrina Schmied investigate the mechanism of a rearrangement that can lead to peptide/protein backbone cleavage.
Thanks to #LEOFondet for funding the project that led to this discovery.
chemrxiv.org/engage/chemr...
Thanks to #LEOFondet for funding the project that led to this discovery.
chemrxiv.org/engage/chemr...