Chalystha Lee
@chalysthalee.bsky.social
🇲🇾 in 🇦🇺, and now 🇺🇸🗽 | postdoc @ nyu | Interested in how the brain in our gut works!
👩🏻🔬 @margolislabnyu.bsky.social
👩🏻🔬 @margolislabnyu.bsky.social
Reposted by Chalystha Lee
👉 We generated a starter pack for #neurogastroenterology and enteric #neuroscience!
Let's connect and bring gut-brain research and clinical neurogastroenterology to the next level! 🌐
go.bsky.app/3Z82PbH
Let's connect and bring gut-brain research and clinical neurogastroenterology to the next level! 🌐
go.bsky.app/3Z82PbH
November 1, 2025 at 6:37 PM
👉 We generated a starter pack for #neurogastroenterology and enteric #neuroscience!
Let's connect and bring gut-brain research and clinical neurogastroenterology to the next level! 🌐
go.bsky.app/3Z82PbH
Let's connect and bring gut-brain research and clinical neurogastroenterology to the next level! 🌐
go.bsky.app/3Z82PbH
Reposted by Chalystha Lee
PRC Highlight: #MargolisLab making strides again! Congrats to Chalystha Lee who received the 2025 ISSR Travel Award at the #ISSR2025 hosted in Vienna! With mentorship from Dr. Kara Margolis & Dr. Michael Gershon lighting the way. #mentorship #ISSR #womeninresearch @chalysthalee.bsky.social
September 10, 2025 at 8:43 PM
PRC Highlight: #MargolisLab making strides again! Congrats to Chalystha Lee who received the 2025 ISSR Travel Award at the #ISSR2025 hosted in Vienna! With mentorship from Dr. Kara Margolis & Dr. Michael Gershon lighting the way. #mentorship #ISSR #womeninresearch @chalysthalee.bsky.social
Reposted by Chalystha Lee
Gabapentin is widely prescribed for nerve pain, but it doesn’t work the same for everyone.
We studied actual human sensory neurons from donors and found that some responded strongly - and others hardly at all.
#fromlabtolife #neuroskyence #PainResearch 1/4
We studied actual human sensory neurons from donors and found that some responded strongly - and others hardly at all.
#fromlabtolife #neuroskyence #PainResearch 1/4
August 7, 2025 at 5:27 PM
Gabapentin is widely prescribed for nerve pain, but it doesn’t work the same for everyone.
We studied actual human sensory neurons from donors and found that some responded strongly - and others hardly at all.
#fromlabtolife #neuroskyence #PainResearch 1/4
We studied actual human sensory neurons from donors and found that some responded strongly - and others hardly at all.
#fromlabtolife #neuroskyence #PainResearch 1/4
Just back from a great week in Vienna for #ISSR2025. I am grateful for the travel award and the opportunity to share my work. Big thanks to @karapedsgastrodoc.bsky.social and Mike Gershon for their steady support in the lab and my career. Loved connecting with 5-HT researchers from around the world!
July 15, 2025 at 3:34 PM
Just back from a great week in Vienna for #ISSR2025. I am grateful for the travel award and the opportunity to share my work. Big thanks to @karapedsgastrodoc.bsky.social and Mike Gershon for their steady support in the lab and my career. Loved connecting with 5-HT researchers from around the world!
@karapedsgastrodoc.bsky.social gave a fantastic talk on the lab's important work on SSRI use in the gastrointestinal tract
@margolislabnyu.bsky.social highlighting @linyhung.bsky.social and @sarahanajjar.bsky.social 's work!
@nyupainresearch.bsky.social
@margolislabnyu.bsky.social highlighting @linyhung.bsky.social and @sarahanajjar.bsky.social 's work!
@nyupainresearch.bsky.social
July 8, 2025 at 9:07 AM
@karapedsgastrodoc.bsky.social gave a fantastic talk on the lab's important work on SSRI use in the gastrointestinal tract
@margolislabnyu.bsky.social highlighting @linyhung.bsky.social and @sarahanajjar.bsky.social 's work!
@nyupainresearch.bsky.social
@margolislabnyu.bsky.social highlighting @linyhung.bsky.social and @sarahanajjar.bsky.social 's work!
@nyupainresearch.bsky.social
Reposted by Chalystha Lee
What do you think these #painresearch results from Ullrich et al. in Science Advances may mean for finding the patterns behind ligand bias? bit.ly/4elhYYE
June 30, 2025 at 4:00 PM
What do you think these #painresearch results from Ullrich et al. in Science Advances may mean for finding the patterns behind ligand bias? bit.ly/4elhYYE
Reposted by Chalystha Lee
Congratulations @tonelloraquel.bsky.social and @mariafialho.bsky.social !! Fantastic work!
Excited to share my first senior author paper in Pain! 🎉 We identify Synaptojanin 1 & Endophilin A1 as key endocytic mediators of nociception. Silencing them blocks spinal synaptic transmission and relieves pain in cancer & postoperative models, without affecting normal behavior.
buff.ly/caKMGY3
buff.ly/caKMGY3
buff.ly
June 11, 2025 at 8:13 PM
Congratulations @tonelloraquel.bsky.social and @mariafialho.bsky.social !! Fantastic work!
Congratulations @sarahanajjar.bsky.social & @linyhung.bsky.social !! 🙌🥳
🎉 Big wins for the Margolis Lab at AMPIRS 2025!
👏 Chalystha and Lin rocked their talks, Taeseon and Daniel nailed their posters, and Sarah delivered an epic flash talk!
🏆 Huge congrats to Lin and Sarah for taking 1st place! So proud of this amazing team! 💜🧠
@karapedsgastrodoc.bsky.social
👏 Chalystha and Lin rocked their talks, Taeseon and Daniel nailed their posters, and Sarah delivered an epic flash talk!
🏆 Huge congrats to Lin and Sarah for taking 1st place! So proud of this amazing team! 💜🧠
@karapedsgastrodoc.bsky.social
June 3, 2025 at 4:28 PM
Congratulations @sarahanajjar.bsky.social & @linyhung.bsky.social !! 🙌🥳
Reposted by Chalystha Lee
BOOM! www.nature.com/articles/s41... I think this is a big step forward for the field. Congrats to Lauren Donovan and @vivtawfik-mdphd.bsky.social and the whole Tawfik lab team.
Aging and injury drive neuronal senescence in the dorsal root ganglia - Nature Neuroscience
The authors describe a susceptibility of the peripheral nervous system to neuronal senescence with age or injury relevant for sensory dysfunction, such as chronic pain.
www.nature.com
May 14, 2025 at 1:53 PM
BOOM! www.nature.com/articles/s41... I think this is a big step forward for the field. Congrats to Lauren Donovan and @vivtawfik-mdphd.bsky.social and the whole Tawfik lab team.
Reposted by Chalystha Lee
I am looking for a postdoc with an immunology background interested in joining a Yale neuroscience lab to study how the brain controls immunity. At Yale, we have a wonderful interdisciplinary & collaborative #neuroimmune community. Please reach out or share with anyone who might be interested!
May 22, 2025 at 11:42 AM
I am looking for a postdoc with an immunology background interested in joining a Yale neuroscience lab to study how the brain controls immunity. At Yale, we have a wonderful interdisciplinary & collaborative #neuroimmune community. Please reach out or share with anyone who might be interested!
Reposted by Chalystha Lee
🚨New paper with @thexavierlab.bsky.social @science.org on the critical role of 🔄neuroimmune crosstalk in immune defense in the gut🪱🪱.
🧪@genelayinstitute.bsky.social @mgbresearch.bsky.social @harvardmed.bsky.social @broadinstitute.org
www.science.org/doi/10.1126/...
🧪@genelayinstitute.bsky.social @mgbresearch.bsky.social @harvardmed.bsky.social @broadinstitute.org
www.science.org/doi/10.1126/...
Type 2 cytokines act on enteric sensory neurons to regulate neuropeptide-driven host defense
Enteric nervous system (ENS)–derived neuropeptides modulate immune cell function, yet our understanding of how inflammatory cues directly influence enteric neuron responses during infection is conside...
www.science.org
May 23, 2025 at 1:26 AM
🚨New paper with @thexavierlab.bsky.social @science.org on the critical role of 🔄neuroimmune crosstalk in immune defense in the gut🪱🪱.
🧪@genelayinstitute.bsky.social @mgbresearch.bsky.social @harvardmed.bsky.social @broadinstitute.org
www.science.org/doi/10.1126/...
🧪@genelayinstitute.bsky.social @mgbresearch.bsky.social @harvardmed.bsky.social @broadinstitute.org
www.science.org/doi/10.1126/...
Reposted by Chalystha Lee
Congrats to @karapedsgastrodoc.bsky.social on becoming part of the 2025 AGA Council section leaders!! Read more👉 gastro.org/news/meet-ou...
Meet our 2025 AGA Council section leaders
Introducing the five members elected to join the AGA Institute Council and lead specialty-based sections.
gastro.org
May 21, 2025 at 6:47 PM
Congrats to @karapedsgastrodoc.bsky.social on becoming part of the 2025 AGA Council section leaders!! Read more👉 gastro.org/news/meet-ou...
Definitely something important to consider wrt our studies in rodent preclinical models!
New study finds microglia-like cells in human DRGs that drive neuronal soma enlargement, axon growth, and somatosensation but are absent in mice 🪤🐁🐀 www.cell.com/cell/fulltex...
Peripheral nervous system microglia-like cells regulate neuronal soma size throughout evolution
An immune cell population found in humans and a number of large vertebrates resembles
microglia of the central nervous system in terms of transcriptome, epigenome, protein
markers, and ontogeny but in...
www.cell.com
April 12, 2025 at 4:40 PM
Definitely something important to consider wrt our studies in rodent preclinical models!
Reposted by Chalystha Lee
🔬 Exciting discovery! We've been curious about the function of unique IBA1+ cell staining we observed around healthy human DRG neurons in the lab (indicated by red arrows). A new paper @cellpress.bsky.social finally provides some answers. Link: www.cell.com/cell/fulltex...
April 8, 2025 at 2:33 PM
🔬 Exciting discovery! We've been curious about the function of unique IBA1+ cell staining we observed around healthy human DRG neurons in the lab (indicated by red arrows). A new paper @cellpress.bsky.social finally provides some answers. Link: www.cell.com/cell/fulltex...
Reposted by Chalystha Lee
We have slots for 2-3 postbacs! Get in touch if you’re interested in joining the Affective Neuroscience and Pain lab & contributing to our studies of pain, emotion, and social processing in the 🧠
Recruitment of postbacs & postdocs in the NIH IRP has resumed. I have no additional info beyond what is publicly stated on the website. www.training.nih.gov/research-tra...
April 7, 2025 at 7:14 PM
We have slots for 2-3 postbacs! Get in touch if you’re interested in joining the Affective Neuroscience and Pain lab & contributing to our studies of pain, emotion, and social processing in the 🧠
Reposted by Chalystha Lee
Please spread the word! We have an opening in the Atkinson lab for a post-doc with a focus on the molecular mechanisms of microbial immune systems. Can be a fully computational or experimental or hybrid project.
Read more and apply here:
lu.varbi.com/en/what:job/...
#phage #bioinformatics
Read more and apply here:
lu.varbi.com/en/what:job/...
#phage #bioinformatics
Postdoctoral research fellow with a focus on the molecular mechanisms of bacteriophage-host interactions
Description of the Workplace In the Atkinson lab we are interested in making discoveries about protein function and structure, with a focus on bacterial immune system components that protect against b
lu.varbi.com
April 8, 2025 at 6:19 AM
Reposted by Chalystha Lee
How is the input of the different kinds of primary sensory neurons responding to heat and mechanical stimuli summarized in the spinal cord? Check out our recent study.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Neural ensembles that encode nocifensive mechanical and heat pain in mouse spinal cord - Nature Neuroscience
Zhang et al. identify unimodal neural representations in the spinal cord of cutaneous mechanical and heat stimuli gated by a shared feed-forward local inhibitory neuron type and a neural transition du...
www.nature.com
March 24, 2025 at 4:07 PM
How is the input of the different kinds of primary sensory neurons responding to heat and mechanical stimuli summarized in the spinal cord? Check out our recent study.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Chalystha Lee
CONGRATULATIONS to Drs. Sarah Najjar, Lin Hung and Kara Margolis- Their review article: Serotonergic Control of Gastrointestinal Development, Motility, and Inflammation is one of the top 10 most cited articles published in 2023! onlinelibrary.wiley.com/doi/abs/10.100… 🥳🔝🔟
March 20, 2025 at 6:23 PM
CONGRATULATIONS to Drs. Sarah Najjar, Lin Hung and Kara Margolis- Their review article: Serotonergic Control of Gastrointestinal Development, Motility, and Inflammation is one of the top 10 most cited articles published in 2023! onlinelibrary.wiley.com/doi/abs/10.100… 🥳🔝🔟
Reposted by Chalystha Lee
Our program manager extraordinaire, Ayesha Ahmad, is leaving us, so we have an exciting position open to take on her role. jobs.utdallas.edu/postings/28956 In addition to this being an exciting position, you will also get to learn from Ayesha before she departs.
Program Manager I
This position will be responsible for managing and overseeing the day-to-day operations of the Human Nociceptor and Spinal Cord Molecular Signature Center under the direction of Dr. Ted Price. Key dut...
jobs.utdallas.edu
March 19, 2025 at 2:56 PM
Our program manager extraordinaire, Ayesha Ahmad, is leaving us, so we have an exciting position open to take on her role. jobs.utdallas.edu/postings/28956 In addition to this being an exciting position, you will also get to learn from Ayesha before she departs.
Reposted by Chalystha Lee
Looking for an excellent & highly motivated postdoctoral researcher to join our team to develop an exciting project focused on the generation of beneficial Innate Lymphoid Cells #ILC for the treatment of Inflammatory Bowel Disease #IBD using #organoids. Please share!
www.kcl.ac.uk/jobs/109186-...
www.kcl.ac.uk/jobs/109186-...
www.kcl.ac.uk
March 3, 2025 at 9:19 AM
Looking for an excellent & highly motivated postdoctoral researcher to join our team to develop an exciting project focused on the generation of beneficial Innate Lymphoid Cells #ILC for the treatment of Inflammatory Bowel Disease #IBD using #organoids. Please share!
www.kcl.ac.uk/jobs/109186-...
www.kcl.ac.uk/jobs/109186-...
So excited to share what I've been up to in the past year at the 2025 Serotonin Meeting in Vienna! Can't wait for July! Thank you ISSR for this travel grant! @margolislabnyu.bsky.social
Congratulations to @chalysthalee.bsky.social 🎉on being awarded the Travel Award to the International Society for Serotonin Research (ISSR) 2025 meeting in Vienna, Austria this July! ✈️👏🧠
@karapedsgastrodoc.bsky.social
www.serotoninclub.org/2025-meeting
@karapedsgastrodoc.bsky.social
www.serotoninclub.org/2025-meeting
2025 Meeting | ISSR
www.serotoninclub.org
March 5, 2025 at 1:48 AM
So excited to share what I've been up to in the past year at the 2025 Serotonin Meeting in Vienna! Can't wait for July! Thank you ISSR for this travel grant! @margolislabnyu.bsky.social
Reposted by Chalystha Lee
#GastroEdPick Intestinal crypt microbiota modulates intestinal stem cell turnover and tumorigenesis via indole acetic acid @naturemicrobiol.bsky.social www.nature.com/articles/s41...
Intestinal crypt microbiota modulates intestinal stem cell turnover and tumorigenesis via indole acetic acid - Nature Microbiology
Intestinal crypt-resident Acinetobacter radioresistens secretes indole acetic acid which activates an Ahr-Wnt-β-catenin-EphB2 signalling axis to promote intestinal stem cell homeostasis and prevent tu...
www.nature.com
March 3, 2025 at 9:51 AM
#GastroEdPick Intestinal crypt microbiota modulates intestinal stem cell turnover and tumorigenesis via indole acetic acid @naturemicrobiol.bsky.social www.nature.com/articles/s41...