#neuroimmune
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jdpereira.bsky.social
Let me share my greatest handicap in science: we just got some really, really cool neuroimmune data for ALS.

And I really want to share it.

Which hurts my competitiveness.

At the end of the day, who needs bragging rights? If someone else solves ALS, I will be very, very happy.
a young boy sits at a table with his eyes closed and says " works for me " netflix
ALT: a young boy sits at a table with his eyes closed and says " works for me " netflix
media.tenor.com
November 4, 2025 at 6:10 PM
castltrastondrs.bsky.social
@ofidjournal.bsky.social
academic.oup.com/ofid/article...
Although the underlying mechanisms remain unclear, accumulating evidence implicates that persistent viral antigens & dysregulated neuroimmune responses may drive the development of #neurocovid
Global Prevalence of Long COVID, Its Subtypes, and Risk Factors: An Updated Systematic Review and Meta-analysis
Quantitative evidence shows a persistent prevalence of long COVID globally, with a significant burden of symptoms that last 1–2 years postinfection, unders
academic.oup.com
October 31, 2025 at 7:06 PM
andrewmendiola.bsky.social
Excited to share some research highlights today during the neuroimmune sessions at KAI2025, beautiful day in Incheon, Korea
October 30, 2025 at 10:38 PM
labwaggoner.bsky.social
Cancer cells co-opt an inter-organ neuroimmune circuit to escape immune surveillance @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
October 28, 2025 at 2:41 AM
ennuiwinehouse.bsky.social
As a patient who lives with a chronic neuroimmune condition, this is, politely, fucking bullshit. I understand medical terminology. Don't talk to me like a child. FATIGUE IS NOT THE SAME AS TIREDNESS. Tiredness is resolved by rest. Fatigue doesn't.
October 27, 2025 at 3:42 PM
chromatowski.bsky.social
The other is to use the International Consensus Criteria’s definition for PENE (post-exertional neuroimmune exhaustion), which characterizes the phenomenon in greater detail.
1. Marked, rapid physical and/or cognitive fatigability in response to exertion, which may be minimal such as activities of daily living or simple mental tasks, can be debilitating and cause a relapse. 2. Postexertional symptom exacerbation: e.g. acute flu-like symptoms, pain and worsening of other symptoms. 3. Postexertional exhaustion may occur immediately after activity or be delayed by hours or days. 4. Recovery period is prolonged, usually taking 24h or longer. A relapse can last days, weeks or longer. 5. Low threshold of physical and mental fatigability (lack of stamina) results in a substantial reduction in pre-illness activity level.
October 25, 2025 at 7:20 PM
rogerslabucd.bsky.social
Our department @ucdavisvetmed.bsky.social @ucdavis.bsky.social is hiring! We welcome research that diversifies or complements existing strengths in gastrointestinal, neuroimmune, musculoskeletal, cardiorespiratory
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
Faculty Position in Anatomy, Physiology & Cell Biology We are seeking an outstanding integrative physiologist (broadly defined) for the position of Assistant Professor (tenure track) to join our faculty in the Department of Anatomy, Physiology, and Cell Biology in the School of Veterinary Medicine (SVM), UC Davis. Our department is a highly integrated group of faculty studying molecular, cellular, physiological, and pathophysiological mechanisms of health and disease. The candidate should have an active research program that focuses on interdisciplinary physiology research using state-of- the-art approaches. We welcome research which diversifies our expertise, and/or that which complements existing strengths in gastrointestinal, neuroimmune, musculoskeletal, cardiorespiratory systems as well as developmental biology. Candidates are expected to expand access to education and provide opportunities in research for students, trainees, and the community across various life and professional experiences. • Candidates must possess a PhD and postdoctoral experience in physiology or a related field. • Aptitude/experience in teaching broad-based physiology or functional anatomy to professional or graduate students. • Experience with grant writing. • Excellent interpersonal and communication skills, and a demonstrated ability to work cooperatively and collegially within a diverse community. Sunrise at UC Davis School of Veterinary Medicine Sunrise in Davis CA
October 22, 2025 at 10:44 PM
ertrunnell.bsky.social
By integrating cerebral #organoids with microglia-like cells derived from familial Alzheimer’s disease patient iPSCs, @uthealthhouston.bsky.social scientists developed a neuroimmune #assembloid model that faithfully reproduces Alzheimer's inflammatory hallmarks.

#alzsky #neuroskyence 🧪
“Murine models do not consistently replicate human CNS physiology, thereby failing to reflect pathological characteristics such as [neurodegnerative] disease onset or progression accurately.” “This discrepancy likely arises from inter-species variability in [CNS] complexity, structure, and inflammatory responses, which constrains a complete reproduction of the pathophysiological alterations seen in humans. Unlike other species, human microglia exhibit heterogeneity in transcriptional states.” “Moreover, significant differences in various gene modules between rodent and primate microglia exist. These differences include genes associated with complement pathways, phagocytosis, and susceptibility to neurodegenerative conditions like AD and Parkinson’s disease.”
October 23, 2025 at 12:32 PM
nicolecrust.bsky.social
Onto Part B of Day 1: Molecular messengers & systemic signals.

First up: Constantino Iadecola (Weill Cornell Med) who studies the "neurovascular / neuroimmune interactions" & brain health in stroke and high blood pressure.

We have 400 miles of blood vessels in our brains (wow!).
slide from talk
October 22, 2025 at 5:37 PM
sueponcin.com
The “transdiagnostic genetic vulnerability that reaches far beyond FM affecting core neurobiological systems:
central nervous system excitability, dopaminergic/serotonergic signaling, neuroimmune stress

It is found in ME/CFS, chronic pain conditions, IBS, PTSD, depression”

Identifiers ➡️treatment
October 21, 2025 at 2:12 AM
liapas.bsky.social
This week is #InvisibleDisabilitiesWeek. My chronic illnesses are an invisible disability, especially #MECFS. ME/CFS is a neuroimmune disease that has a worse quality of life measurement than any other. This #Sciart #symptomatology #embroidery, body map, maps out my symptoms as they were in 2016.

An outline of a naked woman is embroidered on linen in the same bone white colour as the linen. She stands legs together, her right hand covering her groin, her left hand, palm up, extended slightly to her side. She looks to the right. Her entire body except for her belly is covered in intricate markings representing different neurological sensations. Her face is a mask of green lines, feathery grey lines cover her shoulders and chest. There is a thick band of intricate burgundy stitching around her waist. Her forearms and hands are covered in thick blue undulant lines. Her right leg has bands of burgundy along the muscles, with small dots around them. Her inner left leg has a thick line of blue running up it, with thin branches spreading towards her outer leg.
October 19, 2025 at 4:03 PM
labwaggoner.bsky.social
Preprint: The Autoantibodyome Neuroimmune Signature of Neurodegeneration
papers.ssrn.com/sol3/papers....
October 7, 2025 at 4:58 PM
emilyesfraser.bsky.social
Lolsob at the person who decided my neuroimmune disease is fake because they didn’t want to mask for me anymore
jenka.bsky.social Jenka @jenka.bsky.social · Oct 1
I learned this term yesterday and my life will never be the same.
"Solution Aversion": Denying a problem when you do not like the solution.
October 7, 2025 at 3:46 AM
animalsocaging.bsky.social
✨ 🔦 Research Network Spotlight! 🔦 ✨

Dr. Millie Rincón-Cortés at the University of Texas at Dallas is one of two recipients of a 2025-2026 Pilot & Feasibility award from our Research Network. Check out a description of her project on early life programming and neuroimmune aging in the image below.
October 6, 2025 at 10:55 PM
drinfosec.bsky.social
🚨🧵by @vipintukur on a study about #LongCovid

"#LongCOVID isn’t just 'post-virus fatigue.' A new review maps out how the nervous system + immune system cross-talk drives symptoms like brain fog, dysautonomia, neuropathy & fatigue..."

Full 🧵
threadreaderapp.com/thread/19734...
#LongCOVID isn’t just “post-virus fatigue.” A new review maps out how the nervous system + immune system cross-talk drives symptoms like brain fog, dysautonomia, neuropathy & fatigue. It draws from autopsies, animal models & human data to piece together the neuroimmune puzzle. 1/
October 1, 2025 at 8:50 PM
hindhussein.bsky.social
Hello everyone! I am a postdoc in mucosal immunology and I am looking for new postdoc position in Europe! I know a lot about gut mast cells, but also CD4 T cells and type 2/3 immunity in general. I've worked with single cell sequencing and neuroimmune interactions. Feel free to share! Thank you! ♥️🥼👩‍🔬
September 24, 2025 at 8:07 PM
boghuma.bsky.social
Shingrix’s AS01 adjuvant produces an unusually strong innate + T-cell boost (MPL + QS-21) that plausibly (a) prevents VZV-driven neuroinflammation and/or (b) triggers durable innate/“trained” immune changes that reduce neuroimmune risk but the human data are observational & causality is not proven.
September 23, 2025 at 12:33 PM
drinfosec.bsky.social
From 👆
Conclusion Long COVID significantly affected people's mental and physical well-being and contributed to the development of neuropsychiatric manifestation. Emerging evidence shows that it might be the interplay between neuroimmune dysregulation, virus-induced brain injury, and neuroinflammation that leads to these neuropsychiatric manifestations and accelerates disease progression. Medications employed for COVID-19 management also can induce neuropsychiatric symptoms. This review attempts to bring together
September 22, 2025 at 2:03 AM
nyupainresearch.bsky.social
Thank you Brian Kim, MD, MTR for visiting the #NYU #PRC, giving a spectacular talk on neuroimmune interactions in bladder hypersensitivity and meeting with our members!
September 19, 2025 at 7:20 PM
nordvvind.bsky.social
Schalten.

Was ansonsten für Leute hier im Thread beschreiben, neuroimmune Prozesse bei Infekten machen dies gerne bei peripheren nerven, insbesondere in der Haut. Ameisenlaufen, Kribbeln, erhöhte Schmerzhaftigkeit auf Berührung. Weil die peripheren nerven zu viel feuern, fällt die Interpretation
September 19, 2025 at 11:33 AM
ukglia.bsky.social
📢 2 PhD positions on the role of GLIA in brain function 📢

Neuronal Clues to Astrocytes in the Developing Brain https://
tinyurl.com/4m3uuf2a
Neuroimmune strategy to treat Alzheimer’s disease https://
tinyurl.com/c7stnur5

#opportunities #neuroscience #neuroskyence #graduates
Neuronal Clues to Astrocytes: Uncovering Hidden Mechanisms in the Developing Brain. MRC GW4 BioMed DTP PhD studentship for 2026/27 Entry, Department of Clinical and Biomedical Science at University of...
PhD Project - Neuronal Clues to Astrocytes: Uncovering Hidden Mechanisms in the Developing Brain. MRC GW4 BioMed DTP PhD studentship for 2026/27 Entry, Department of Clinical and Biomedical Science at...
tinyurl.com
September 17, 2025 at 9:13 AM
justahousewife.bsky.social
Premed -> biomimetic nanomaterials via some psychotic episodes making me unfit. Turns out it is epilepsy with maybe neuroimmune trigger.
September 13, 2025 at 5:32 PM
mortuaryreport.bsky.social
i cannot help but wonder, with the information coming out of MUSC about hypermobile Ehlers-Danlos likely being neuroimmune-related instead of collagen related, & with the venn diagram of hEDs & endo occurrence, if this information might be used at cross purposes for dual diagnostics
lilithsaintcrow.com Lili Saintcrow @lilithsaintcrow.com · Sep 11
"Menstrual blood was messy, it was imprecise, it was difficult to collect, OB-GYNs told the pair. Why bother when the disease could be diagnosed with surgery?"

(Which is an absolutely appalling state of affairs for a vocation which first must "do no harm", I might add.)
PROBING THE PAIN
Katie Burns is helping uncover the role of the immune system in endometriosis—while managing the disease herself.
www.science.org
September 12, 2025 at 2:28 AM
tomkindlon.bsky.social
Great to see a UK GP writing a BMJ e-letter like this:

"Research must consider Post Exertional Malaise as a neurological event underpinning fluctuating cognitive dysfunction in Long Covid"

www.bmj.com/content/390/...

#PEM #LongCovid
PEM warrants recognition as a neurological pathology resulting from metabolic and immune dysregulation (3). Approximately 48 hr after a triggering event—physical, cognitive, or emotional—patients experience what is colloquially termed a “crash.” This involves a surge in neurological symptoms that may render them unable to function: profound fatigue, cognitive slowing, hypersomnia, photophobia, phonophobia, tinnitus, nausea, headaches, migraines, executive dysfunction, word-finding difficulties, working memory impairment, pain, and worsening dysautonomia with orthostatic intolerance, mood disorders. Although these symptoms may be present at baseline, they rapidly escalate in the disabling cacophony of the “crash”. Many patients report diurnal variation, with symptoms peaking midday and easing somewhat towards night, repeating daily until resolution, suggesting a neuroimmune process with a circadian rhythm. Patients often experience disablement until the episode resolves over days or weeks.
September 10, 2025 at 11:57 PM
stanford-chemh.bsky.social
Juan Inclan Rico @juaninclanrico.bsky.social from the University of Pennsylvania discusses neuroimmune modulation, specifically the role of itch-sensing neurons in promoting skin immunity against parasitic worms.
September 10, 2025 at 6:13 PM