Julia Sero
@cellmorphosero.bsky.social
How cells stick to things and move around, microscopy, cats, garden bugs, forays into machine learning, occasional political snark. Asst Prof University of Bath, UK 🏳️🌈
Reposted by Julia Sero
It’s officially potluck season withoffice parties galore. 🦃🥘 If, like me, you harbor an irrational fear of food poisoning, I’ve got you covered. Here’s your ID doctor–approved guide to surviving the season’s buffets w/out ending up in the ER.
🧤🍽️💀
open.substack.com/pub/bktitanj...
🧤🍽️💀
open.substack.com/pub/bktitanj...
An ID Doctor’s Guide to Surviving Holiday Potlucks Food Poisoning Free
Because nothing says “festive” like avoiding an impromptu Norovirus outbreak.
open.substack.com
November 10, 2025 at 3:05 PM
It’s officially potluck season withoffice parties galore. 🦃🥘 If, like me, you harbor an irrational fear of food poisoning, I’ve got you covered. Here’s your ID doctor–approved guide to surviving the season’s buffets w/out ending up in the ER.
🧤🍽️💀
open.substack.com/pub/bktitanj...
🧤🍽️💀
open.substack.com/pub/bktitanj...
Reposted by Julia Sero
Ever wondered if analyzing your images by using intensity Z-projections impacts your data?
Happy to announce my guest article in Microscopy & Analysis on that topic. It's a very short read but worth for everyone dealing with image analysis!
buff.ly/KJ147tI
#Microscopy #ZProjection #ImageAnalysis
Happy to announce my guest article in Microscopy & Analysis on that topic. It's a very short read but worth for everyone dealing with image analysis!
buff.ly/KJ147tI
#Microscopy #ZProjection #ImageAnalysis
November 10, 2025 at 4:05 PM
Ever wondered if analyzing your images by using intensity Z-projections impacts your data?
Happy to announce my guest article in Microscopy & Analysis on that topic. It's a very short read but worth for everyone dealing with image analysis!
buff.ly/KJ147tI
#Microscopy #ZProjection #ImageAnalysis
Happy to announce my guest article in Microscopy & Analysis on that topic. It's a very short read but worth for everyone dealing with image analysis!
buff.ly/KJ147tI
#Microscopy #ZProjection #ImageAnalysis
Oh, I want to be a dolphin for a day!
November 11, 2025 at 6:51 AM
Oh, I want to be a dolphin for a day!
Reposted by Julia Sero
Oh, I love this. A new species of sea anemone was discovered recently that parks itself on top of a hermit crab shell like a hat. It seems to feed partly off the crab's faeces, but it also excretes a hard shell that extends the crab's home. In return, it's carried around the seafloor like a king.
November 10, 2025 at 9:57 PM
Oh, I love this. A new species of sea anemone was discovered recently that parks itself on top of a hermit crab shell like a hat. It seems to feed partly off the crab's faeces, but it also excretes a hard shell that extends the crab's home. In return, it's carried around the seafloor like a king.
Reposted by Julia Sero
A wonderful collaboration between my lab and Andy Ellington and Edward Marcotte here at UT.
We obtained lots of thermal stable plastic degrading enzymes from the deep sea (Guaymas Basin, Gulf of California)
We obtained lots of thermal stable plastic degrading enzymes from the deep sea (Guaymas Basin, Gulf of California)
Plastic degradation by enzymes from uncultured deep sea microorganisms
Abstract. Polyethylene terephthalate (PET)-hydrolyzing enzymes (PETases) are a recently discovered enzyme class capable of plastic degradation. PETases are
academic.oup.com
November 10, 2025 at 6:04 PM
A wonderful collaboration between my lab and Andy Ellington and Edward Marcotte here at UT.
We obtained lots of thermal stable plastic degrading enzymes from the deep sea (Guaymas Basin, Gulf of California)
We obtained lots of thermal stable plastic degrading enzymes from the deep sea (Guaymas Basin, Gulf of California)
Good interviews by my PhD supervisor, Don Ingber, and one of my rotation lab PIs and advisory committee members, Joan Brugge. Both epic scientists and good people.
youtu.be/J1vXMTTxL1w?...
youtu.be/J1vXMTTxL1w?...
What's at risk when federal research funding to universities is cut | 60 Minutes
YouTube video by 60 Minutes
youtu.be
November 10, 2025 at 1:37 PM
Good interviews by my PhD supervisor, Don Ingber, and one of my rotation lab PIs and advisory committee members, Joan Brugge. Both epic scientists and good people.
youtu.be/J1vXMTTxL1w?...
youtu.be/J1vXMTTxL1w?...
Reposted by Julia Sero
Before ACA, many Americans couldn’t afford insurance
Alex Smith was a diabetic who got kicked off his Mom’s insurance at 26
He made 35k a year which was “too much” for Medicaid, but not nearly enough to cover insurance premiums
He had to ration his insulin & died a month after losing insurance
Alex Smith was a diabetic who got kicked off his Mom’s insurance at 26
He made 35k a year which was “too much” for Medicaid, but not nearly enough to cover insurance premiums
He had to ration his insulin & died a month after losing insurance
Insulin's High Cost Leads To Lethal Rationing
Alec Raeshawn Smith was 23 when diagnosed with Type 1 diabetes and 26 when he died. He couldn't afford $1,300 per month for his insulin and other diabetes supplies, so he tried to stretch the doses.
www.npr.org
November 10, 2025 at 5:01 AM
Before ACA, many Americans couldn’t afford insurance
Alex Smith was a diabetic who got kicked off his Mom’s insurance at 26
He made 35k a year which was “too much” for Medicaid, but not nearly enough to cover insurance premiums
He had to ration his insulin & died a month after losing insurance
Alex Smith was a diabetic who got kicked off his Mom’s insurance at 26
He made 35k a year which was “too much” for Medicaid, but not nearly enough to cover insurance premiums
He had to ration his insulin & died a month after losing insurance
Reposted by Julia Sero
Peiyao Fan, Yang Chen et al. @pku1898.bsky.social show that tubular ER extends into retraction fibers and #migrasomes through #microtubule-dependent ER extension and ER-plasma membrane contact sites in migrating cells. rupress.org/jcb/article/...
#ER_literature #Migration #Organelles
#ER_literature #Migration #Organelles
November 6, 2025 at 5:00 PM
Peiyao Fan, Yang Chen et al. @pku1898.bsky.social show that tubular ER extends into retraction fibers and #migrasomes through #microtubule-dependent ER extension and ER-plasma membrane contact sites in migrating cells. rupress.org/jcb/article/...
#ER_literature #Migration #Organelles
#ER_literature #Migration #Organelles
😯
Looks like this is real. About 40% of the flight at 8k feet, then bumped up to 10k, and then finally went up higher, but only to 20k feet. Much slower than normal flight and likely burned a lot more fuel. But the view out the window was probably impressive.
www.flightaware.com/live/flight/...
www.flightaware.com/live/flight/...
November 9, 2025 at 10:40 PM
😯
This is all so fuxked up. You shouldn't need an economics degree to access basic medical care. Or complex medical care! This is something every single person will need unless they die young, suddenly. Healthcare shpuld not be for profit. It's a fundamental service for a maintaining society.
It's open enrollment time so here's a convenient peg to hang a little tutorial about how to choose your health insurance.
Most of the advice you get is bad. Most of your instincts are bad. I however used to work for a health insurance company and I do arithmetic for a living so I can help.
Most of the advice you get is bad. Most of your instincts are bad. I however used to work for a health insurance company and I do arithmetic for a living so I can help.
Personally I think it's great that my company's HR sends out an official looking tool where they even ask you to pre-populate your healthcare providers and instead of being the actual insurance enrollment process it's just some bullshit checklist to try and convince me I actually don't want a PPO
November 9, 2025 at 9:53 PM
This is all so fuxked up. You shouldn't need an economics degree to access basic medical care. Or complex medical care! This is something every single person will need unless they die young, suddenly. Healthcare shpuld not be for profit. It's a fundamental service for a maintaining society.
Reposted by Julia Sero
ICYMI: New Online! Microtubules provide a mechanical link for YAP/TAZ signalling
Microtubules provide a mechanical link for YAP/TAZ signalling
Nature Reviews Molecular Cell Biology, Published online: 05 November 2025; doi:10.1038/s41580-025-00929-xA study finds that mechanical activation leads to microtubule rearrangement, facilitating the proteasomal degradation of an inhibitor of YAP/TAZ, thus promoting YAP/TAZ nuclear translocation.
bit.ly
November 8, 2025 at 3:54 PM
ICYMI: New Online! Microtubules provide a mechanical link for YAP/TAZ signalling
Reposted by Julia Sero
I love to see the endoplasmic reticulum (ER, cyan) hitchhiking over microtubules (MTs, orange).
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
November 7, 2025 at 9:25 PM
I love to see the endoplasmic reticulum (ER, cyan) hitchhiking over microtubules (MTs, orange).
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
Reposted by Julia Sero
A man rushed to the Broadview ICE facility searching for his wife. They followed every legal step, but ICE took her into another room and she vanished. He tracked her phone there when the signal died. Police told him to “look up her name online.” He sat in the parking lot, weeping, with no answers.
November 9, 2025 at 1:34 PM
A man rushed to the Broadview ICE facility searching for his wife. They followed every legal step, but ICE took her into another room and she vanished. He tracked her phone there when the signal died. Police told him to “look up her name online.” He sat in the parking lot, weeping, with no answers.
Reposted by Julia Sero
A critical role of FAK signaling in Rac1-driven melanoma cell resistance to MAPK pathway inhibition
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A critical role of FAK signaling in Rac1-driven melanoma cell resistance to MAPK pathway inhibition - Oncogene
Oncogene - A critical role of FAK signaling in Rac1-driven melanoma cell resistance to MAPK pathway inhibition
www.nature.com
November 9, 2025 at 12:27 PM
A critical role of FAK signaling in Rac1-driven melanoma cell resistance to MAPK pathway inhibition
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Julia Sero
This is why I, as a clinician, strongly support a single-payer system.
Think of it like the fire department. The modern fire department started as an insurance you could purchase; it ended as a public good, funded by all.
Healthcare is no different.
Think of it like the fire department. The modern fire department started as an insurance you could purchase; it ended as a public good, funded by all.
Healthcare is no different.
November 9, 2025 at 7:38 AM
This is why I, as a clinician, strongly support a single-payer system.
Think of it like the fire department. The modern fire department started as an insurance you could purchase; it ended as a public good, funded by all.
Healthcare is no different.
Think of it like the fire department. The modern fire department started as an insurance you could purchase; it ended as a public good, funded by all.
Healthcare is no different.
Timeline cleanse!!!
Loving today's news that the mysterious "fedora man" outside the Louvre heist was actually a 15-year-old museum visitor who dresses like a 1940s French detective all the time, just because. apnews.com/article/louv...
Fedora man unmasked: Meet the teen behind the Louvre mystery photo
Fifteen-year-old Pedro Elias Garzon Delvaux has become an internet sensation after an Associated Press photo captured him outside the Louvre on the day of a crown jewels heist.
apnews.com
November 9, 2025 at 2:34 PM
Timeline cleanse!!!
Reposted by Julia Sero
Beating iPSC-derived heart muscle cells videoed through a microscope. Alpha-actinin-2 is shown. #CellBiology
November 9, 2025 at 3:12 AM
Beating iPSC-derived heart muscle cells videoed through a microscope. Alpha-actinin-2 is shown. #CellBiology
November 9, 2025 at 10:11 AM
Reposted by Julia Sero
This is a glimpse of the cytoskeletal structures we found doing U-ExM in more than 200 species, now in Cell🤩: shorturl.at/6oHvi
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
November 7, 2025 at 1:35 PM
This is a glimpse of the cytoskeletal structures we found doing U-ExM in more than 200 species, now in Cell🤩: shorturl.at/6oHvi
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
Reposted by Julia Sero
This perfectly encapsulates how I feel living in the US. The republican party is an insane death cult, the democratic party is 3 corporations in a trench coat, and the "socialists" are just the completely normal left-wing capitalists you'd find in any of 2 dozen European nations.
Europeans recognize Zohran Mamdani’s supposedly radical policies as ‘normal’
Critics of New York City’s mayor-elect have said his pledges of free bus service and universal childcare are unrealistic, but in Europe it’s a given
www.theguardian.com
November 8, 2025 at 5:18 AM
This perfectly encapsulates how I feel living in the US. The republican party is an insane death cult, the democratic party is 3 corporations in a trench coat, and the "socialists" are just the completely normal left-wing capitalists you'd find in any of 2 dozen European nations.
Stupid Samsung updated itself & now my camera has a several second shutter lag. Downloaded another damn app to turn on "quick tap shutter" - slightly better but still laggy. Victorian RBF portraits only. No chance of catching the cats doing something cute. Overcomplication --> enshittification.
November 8, 2025 at 10:08 AM
Stupid Samsung updated itself & now my camera has a several second shutter lag. Downloaded another damn app to turn on "quick tap shutter" - slightly better but still laggy. Victorian RBF portraits only. No chance of catching the cats doing something cute. Overcomplication --> enshittification.
Reposted by Julia Sero
5. Effectively, people belonged to those who could wield terror and violence. Tyranny, terror and bondage are, I believe, the default state of centralised, hierarchical societies. The freedoms we enjoy today are highly contingent and unusual.
November 7, 2025 at 6:39 AM
5. Effectively, people belonged to those who could wield terror and violence. Tyranny, terror and bondage are, I believe, the default state of centralised, hierarchical societies. The freedoms we enjoy today are highly contingent and unusual.
Reposted by Julia Sero
1. This is a thread on freedom, and how easy it is to lose.
Over the past 2,000 years in Europe, there have been few periods and places of freedom. For much of the time we lived under highly oppressive tyrannies of various kinds, whether small or grand, local or imperial, secular or religious.🧵
Over the past 2,000 years in Europe, there have been few periods and places of freedom. For much of the time we lived under highly oppressive tyrannies of various kinds, whether small or grand, local or imperial, secular or religious.🧵
November 7, 2025 at 6:35 AM
1. This is a thread on freedom, and how easy it is to lose.
Over the past 2,000 years in Europe, there have been few periods and places of freedom. For much of the time we lived under highly oppressive tyrannies of various kinds, whether small or grand, local or imperial, secular or religious.🧵
Over the past 2,000 years in Europe, there have been few periods and places of freedom. For much of the time we lived under highly oppressive tyrannies of various kinds, whether small or grand, local or imperial, secular or religious.🧵
Reposted by Julia Sero
We finally made it over here ! And excited to share our new paper on mechanical forces regulating stem cell plasticity in colorectal cancer, involving force transduction via mechanosensitive calcium channels! www.cell.com/cell-reports...
Mechanosensitive calcium channels and integrins coordinate the reprogramming of colorectal cancer cells into a fetal-like state
van der Net et al. show that mechanical interactions with the stromal component collagen
I trigger reprogramming of colorectal cancer cells into a fetal-like state, through
mechanosensitive integrins ...
www.cell.com
November 7, 2025 at 4:33 PM
We finally made it over here ! And excited to share our new paper on mechanical forces regulating stem cell plasticity in colorectal cancer, involving force transduction via mechanosensitive calcium channels! www.cell.com/cell-reports...
Reposted by Julia Sero
OK, this "Roman Routefinder" on @nature.com of high-resolution maps for ancient Roman roads is super cool. I'll be spending some time with this tonight: www.nature.com/articles/d41...
‘Google Maps’ for Roman roads reveals vast extent of ancient network
A high-resolution digital map nearly doubles the known length of the ancient road network.
www.nature.com
November 7, 2025 at 6:26 PM
OK, this "Roman Routefinder" on @nature.com of high-resolution maps for ancient Roman roads is super cool. I'll be spending some time with this tonight: www.nature.com/articles/d41...