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cellcommlab.bsky.social
CellComM Lab
@cellcommlab.bsky.social
470 followers 310 following 14 posts
𝗖𝗲𝗹𝗹 𝗖𝗼𝗺𝘮𝘶𝘯𝘪𝘤𝘢𝘵𝘪𝘰𝘯 & 𝗠𝘪𝘨𝘳𝘢𝘵𝘪𝘰𝘯 Lab, headed by
@pjsaez.bsky.social #UKE_HH
We ❤ #CellComm #CellMigration 🧪🔬 tinyurl.com/5n8sss49
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cellcommlab.bsky.social
CellComM Lab @cellcommlab.bsky.social · Jan 24
#CellMigration for #FluorescenceFriday 🧪🔬

If a metastatic #cancer cell is offered 2 paths it decides very fast, bc it does matter where it goes...

OTOH, if a non-cancer #cell is offered 2 options it takes some time to explore and decide.

More in the paper: www.nature.com/articles/s41...
Reposted by CellComM Lab
samuelconnell.3i.social
What a crazy cool paper! First author @pierreucla.bsky.social with a large crew knocked it out of the park. (GIF below from @the.3i.social LLS) Quantifying cell traction forces at the single-fiber scale in 3D: An approach based on deformable photopolymerized fiber arrays www.pnas.org/doi/10.1073/...
November 13, 2025 at 6:21 PM
Reposted by CellComM Lab
ritastrack.bsky.social
I won't talk about NMeth @natmethods.nature.com forever (probably), but I do want to brag a bit about the November focus issue on cell segmentation and tracking, which is many ways is my last hurrah (and final editorial) for the journal. I am so proud of these papers!! www.nature.com/nmeth/volume...
November 13, 2025 at 8:49 PM
Reposted by CellComM Lab
isdb.bsky.social
This week's #FluorescenceFriday, we'll be treated with one of the classical models of #devbio, the neural crest cells. Here is a beautiful video of neural crest cells with GFP-tagged focal adhesion kinase (🔵) and LifeAct-RFP (🟣) migrating on a Fibronectin matrix.
📹: Adam Shellard
November 14, 2025 at 5:45 PM
Reposted by CellComM Lab
pjsaez.bsky.social
I love to see the endoplasmic reticulum (ER, cyan) hitchhiking over microtubules (MTs, orange).

Also the membrane dynamics are lovely.

It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
November 7, 2025 at 9:25 PM
Reposted by CellComM Lab
jytinevez.bsky.social
Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...
Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA
Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...
forum.image.sc
October 7, 2025 at 12:39 PM
Reposted by CellComM Lab
natclarke.bsky.social
🚨 My lab is hiring at all levels!

Interested in animal origins & evolutionary cell biology?

I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.

🔗: clarkelab.com/join/

Please repost!
October 8, 2025 at 5:49 PM
Reposted by CellComM Lab
worzfeld.bsky.social
Interested in doing exciting research on #epithelial #plasticity in the #kidney or #intestine?

Then please check out our recent job ads for #PhD and #Postdoc positions!

www.nature.com/naturecareer...
www.nature.com/naturecareer...
www.nature.com/naturecareer...
www.nature.com/naturecareer...
September 9, 2025 at 4:49 PM
Reposted by CellComM Lab
jboixcampos.bsky.social
I can't imagine a better day of the week to publish this than #FluorescenceFriday: PathoPlex is finally published! 🎉

This presents a revolutionary jump from 4-6 to 100+ markers per sample! 🤯

Read the full story here:
www.nature.com/articles/s41...
July 18, 2025 at 1:24 PM
Reposted by CellComM Lab
pjsaez.bsky.social
#HotFromThePress !!

What if instead of analyzing 4-6 pathology markers you could check >100 in the *same* sample?

@maltekuehl.com & co @puellesv.bsky.social lab introduce #PathoPlex, method that could even predict disease

Full www.nature.com/articles/s41...
@focalplane.bsky.social @nature.com 🧪🔬
July 18, 2025 at 1:14 PM
Reposted by CellComM Lab
sseethar.bsky.social
Excited to be starting my research group as a tenure track Presidential Young Professor at the Mechanobiology Institute @mbisg.bsky.social, and the Dept of Physiology at @nusingapore.bsky.social in the fall! More about our work on vascular mechanobiology in health & disease mechano-medicine-lab.com
July 9, 2025 at 5:00 PM
Reposted by CellComM Lab
pjsaez.bsky.social
This is why we love #cellmigration

#Leukocytes: #Neutrophils (cyan) #Macrophages (orange) chemotaxis.

I couldn't share it before the retirement of @zebrafishrock.bsky.social, but cool #microscopy in #zebrafish continue to rock !

#scicomm #scisky @cellcommlab.bsky.social @focalplane.bsky.social 🧪🔬
July 8, 2025 at 10:18 AM
Reposted by CellComM Lab
jboixcampos.bsky.social
🧵 Neural networks meet cell migration in Valencia!

Hi Bluesky! 👋 I'm Javier, computational biologist @cellcommlab.bsky.social l working at the intersection of AI and cell biology 🖥️🧫
July 1, 2025 at 10:11 AM
Reposted by CellComM Lab
spalaciosm.bsky.social
A very late #FluorescenceFriday.

Reposting one of my favorite timelapses from the past year: EB3-mScarlet3 in a HeLa cell, look at those microtubules grow!
June 28, 2025 at 5:27 PM
Reposted by CellComM Lab
labwaggoner.bsky.social
Immune cell profiling reveals diverse niches of immune residents of the enteric nervous system and potential neuroimmune interactions
www.pnas.org/doi/10.1073/...
June 29, 2025 at 3:03 AM
Reposted by CellComM Lab
manuelacasasoli.bsky.social
Read and enjoy this short article about interesting mathematical shapes (plus.maths.org/content/rand...) to learn about random surfaces and the secrets of the Universe!

♾️ #iTeachMath #Science‪ #Maths
Do not miss @plusmaths.bsky.social
Image by Thomas Budzinski (perso.ens-lyon.fr/thomas.budzi...)
Image Source: https://perso.ens-lyon.fr/thomas.budzinski/pictures.html and https://plus.maths.org/content/random-surfaces-universe#maths "This picture represents a uniform triangulation of the sphere with over 30,000 vertices. Image by Thomas Budzinski, used by permission."
June 29, 2025 at 1:10 PM
Reposted by CellComM Lab
focalplane.bsky.social
📢Our latest preprint list is now up on FocalPlane.
This week’s list focusses on research using microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included.
focalplane.biologists.com/2025/06/27/m...
Microscopy preprints - applications in biology - FocalPlane
Microscopy preprints - applications in biology - News
focalplane.biologists.com
June 27, 2025 at 1:30 PM
Reposted by CellComM Lab
ai4life.bsky.social
The 2nd AI4Life Challenge is live!
Calling the AI & bioimaging community to tackle a key microscopy challenge: removing noise while preserving detail.

📦 Paired noisy/clean datasets
📈 Ground-truth evaluation
🧠 DL focus

Build, test, compete 👉 ai4life.eurobioimaging.eu/challenge-2/
June 27, 2025 at 1:33 PM
Reposted by CellComM Lab
joachimgoedhart.bsky.social
De novo designed bright, hyperstable rhodamine binders for fluorescence microscopy by Bo Huang and team: www.biorxiv.org/content/10.1...
Fig. 4 Super-resolution microscopy in live and fixed cells with Rhobin. (A) Rhobin transiently binds rhodamine molecules and thereby constantly replenishes signal lost through photobleaching of dyes. (B-D) No-wash STED microscopy of live U2OS cells transiently expressing LifeAct-Rhobin2 labeled with 100 nM JFX650. (C, D) Zoom-ins of regions highlighted in (B) imaged either with confocal or STED microscopy. Scale bar: 20 μm (B) and 10 μm (C, D). (E-H) Rhobin enables timelapse STED microscopy of fast ER dynamics with minimal signal loss. U2OS stably expressing N-terminal tag fusions of SEC61B were stained with 1 μM Halo-JFX650 (HaloTag7, reHaloF) or 2 μM SiRhP (Rhobin2) and imaged at a frame rate of 0.387 fps for at least 100 time points. (F, G) Selected frames from timelapse acquisitions of Rhobin2:SEC61B labeled with SiRhP (F) or HaloTag7:SEC61B labeled with Halo-JFX650 (G). Scale bar: 2 μm. (H) Signal .CC-BY-NC 4.0 International licenseavailable under a (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made The copyright holder for this preprintthis version posted June 25, 2025.;https://doi.org/10.1101/2025.06.24.661379doi:bioRxiv preprint 22 loss during timelapse imaging. Mean ± SD signal inside cells over time for indicated constructs. (I-K) PAINT-type super-resolution microscopy with Rhobin. Rhobin2-SEC61B was transiently expressed in U2OS cells and labeled with 5 nM SiRhP after chemical fixation. Imaging under no- wash conditions and near-TIRF illumination. (I) Repeated, but transient binding of SiRhP molecules to Rhobin2 at low nanomolar concentrations can be observed as intensity bursts in intensity time traces extracted from a diffraction-limited area. See movie S3 for raw data of binding-induced blinking. (J) Sum image across 10,000 frames of an image stack, simulating a diffraction-limited image. (K). Reconstructed image from localized molecules in the full stack.
June 26, 2025 at 1:50 PM
Reposted by CellComM Lab
pjsaez.bsky.social
#FluorescenceFriday

#Mitochondria, powerhouse of the #cell were labeled (cyan) and it's possible to visualize how they reach *every* corner to provide energy.

All recorded under the microscope @cellcommlab.bsky.social

#scicomm #sciencesky #microscopy #organelles @focalplane.bsky.social 🧪🔬
June 20, 2025 at 7:24 PM
Reposted by CellComM Lab
pjsaez.bsky.social
This is why we love #cell dynamics !

Look at this #macrophage branching exploring the surroundings videoed under the microscope

This what immune cells do in our body in search of bacteria, viruses and death cells

#microscopy #cellbio #sciencesky @focalplane.bsky.social @cellcommlab.bsky.social 🧪🔬
June 7, 2025 at 10:14 PM
Reposted by CellComM Lab
squeezycellslab.bsky.social
Very excited to share the first preprint from the lab:
www.biorxiv.org/cgi/content/...
We investigated neural crest migration all the way from head to tail of the Zebrafish embryo and we found their nuclei suffer dramatic deformations.
Want to know of they cope with feeling squeezed? 🐟🐠🐟
June 6, 2025 at 9:44 PM
Reposted by CellComM Lab
pjsaez.bsky.social
#CellMigration
Join us today @dgz.bsky.social !!
See you in 1 h (zoom id and password in the pic below)
dgz.bsky.social DGZ.bsky.social @dgz.bsky.social · Apr 11
The next #DGZ Focus Workshop on #CellBiology of the #ImmuneSystem will take place on April 29, organized by @pjsaez.bsky.social & Evi Kiermaier – join us! 🧑‍🔬🧑‍🔬🧬
April 29, 2025 at 9:06 AM
Reposted by CellComM Lab
pjsaez.bsky.social
Join us for this @dgz.bsky.social seminar online with very cool talks about the Cell biology of the immune system

There will be of course some #CellMigration of leukocytes ;)

Speakers: @liz-kurtz.bsky.social, #ZahraaA, @labliston.bsky.social and #StefanU
dgz.bsky.social DGZ.bsky.social @dgz.bsky.social · Apr 11
The next #DGZ Focus Workshop on #CellBiology of the #ImmuneSystem will take place on April 29, organized by @pjsaez.bsky.social & Evi Kiermaier – join us! 🧑‍🔬🧑‍🔬🧬
April 11, 2025 at 2:49 PM
Reposted by CellComM Lab
dgz.bsky.social
The next #DGZ Focus Workshop on #CellBiology of the #ImmuneSystem will take place on April 29, organized by @pjsaez.bsky.social & Evi Kiermaier – join us! 🧑‍🔬🧑‍🔬🧬
April 11, 2025 at 8:27 AM
Reposted by CellComM Lab
pjsaez.bsky.social
An oldie (10 y!) but goodie: cellular interaction at the top! #cellcomm

Video of a T cell (orange) interacting with a target cell (blue)

From Chen et al. @ Betzig lab (@hhmijanelia.bsky.social) game changing paper !!

Full science.org/doi/10.1126/... @focalplane.bsky.social #scicomm #microscopy 🧪🔬
February 18, 2025 at 8:38 PM