Mysterious increase in the motility of these #lysosomes

After adding a non-stimuli treatment the lysosomes (cyan) got crazy (see color coded tracks)
Maybe #mechanosignaling triggered by shear stress?

#Microscopy + #Cells for #FluorescenceFriday 🧪🔬
#SciSky #scicomm #CellBio

#CellMigration for #FluorescenceFriday 🧪🔬

If a metastatic #cancer cell is offered 2 paths it decides very fast, bc it does matter where it goes...

OTOH, if a non-cancer #cell is offered 2 options it takes some time to explore and decide.

More in the paper: www.nature.com/articles/s41...

re-intro to #BSky 🧪🔬

We are the Cell Communication & Migration laboratory (CellComM lab)

We use #microscopy to study organelle, cytoskeleton, & signaling dynamics, and cellular interactions during motility

#organelles #cellmigration #calciumsignaling #cellcomm #scicomm @focalplane.bsky.social

Actin dynamics videoed under the #microscope
#cytoskeleton lovers

Top right zoom looks like tweezers !

( #fluorescencefriday #scicomm @focalplane.bsky.social 🧪🔬 )

Dancing cells videoed under a microscope.
Now the question is what music style is it? Probably salsa ;)

1st video of many that we will post about #CellMigration, which is at the center of our research

@focalplane.bsky.social @pjsaez.bsky.social @the-node.bsky.social 🧪🔬

here the one from the lab !

Now that we can finally enjoy .gif in @bsky.app, let's start with a classic of #CellMigration

Here a movie of collective cell migration during wound healing videoed under a microscope.

#scicomm #bskysci 🧪🔬 @pjsaez.bsky.social

#preprint for #CellMigration lovers

We expanded our recently published model but now for cell moving a more complex network and spanning several junctions.
Spoiler: immune cells explore better the network than slow moving cells.

Full: www.biorxiv.org/content/10.1...
#scicomm #bskysci 🧪🔬

For #CellMigration lovers
How do cells decide when facing a symmetric junction?
The membrane oscillates exploring both directions until one arm wins.
TLDR: this depends on the actin cytoskeleton & cancer cells decide faster than healthy cells #scicomm #bskysci 🧪🔬

Full www.nature.com/articles/s41...

Are we doing #FluorescentFriday here or not yet?
Let's give it a shot anyways for the sake of #science
(and we still wait for .gifs)
#scicomm #bskyscience🔬🧪