Bethan Goulden
@bethangoulden.bsky.social
Rheumatology & GIM | @VersusArthritis Clinical Research Fellow @UCL | Obstetric Medicine & Women's Health | @UKOSS HLH in pregnancy https://tinyurl.com/35rht7bw
Pinned
Great Society of Acute Medicine podcast on HLH with Dr Jessica Manson. Pragmatic, clinically relevant introduction to the disease, and a nod to pregnancy induced HLH too
open.spotify.com/episode/3dpf...
open.spotify.com/episode/3dpf...
HLH (haemophagocytic lymphohistiocytosis)
open.spotify.com
November 10, 2025 at 6:41 PM
Great Society of Acute Medicine podcast on HLH with Dr Jessica Manson. Pragmatic, clinically relevant introduction to the disease, and a nod to pregnancy induced HLH too
open.spotify.com/episode/3dpf...
open.spotify.com/episode/3dpf...
A systematic review of disseminated HSV in pregnancy (including with HLH) - out now. Highlights non-specific symptoms of the disease in pregnancy & how an absence of lesions does not exclude HSV in the unwell, febrile pregnant patient.
#sepsis #HSV #HLH
obgyn.onlinelibrary.wiley.com/doi/10.1111/...
#sepsis #HSV #HLH
obgyn.onlinelibrary.wiley.com/doi/10.1111/...
November 7, 2025 at 6:46 PM
A systematic review of disseminated HSV in pregnancy (including with HLH) - out now. Highlights non-specific symptoms of the disease in pregnancy & how an absence of lesions does not exclude HSV in the unwell, febrile pregnant patient.
#sepsis #HSV #HLH
obgyn.onlinelibrary.wiley.com/doi/10.1111/...
#sepsis #HSV #HLH
obgyn.onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Bethan Goulden
Now published: The 2025 ACR Guideline for the Treatment of Systemic Lupus Erythematosus
📄 Read the paper: acr.tw/47mkegj
ℹ️ See additional content and resources on this guideline at acr.tw/4mbHK4W
#Medsky #Rheumsky #Rheumatology
📄 Read the paper: acr.tw/47mkegj
ℹ️ See additional content and resources on this guideline at acr.tw/4mbHK4W
#Medsky #Rheumsky #Rheumatology
November 3, 2025 at 4:35 PM
Now published: The 2025 ACR Guideline for the Treatment of Systemic Lupus Erythematosus
📄 Read the paper: acr.tw/47mkegj
ℹ️ See additional content and resources on this guideline at acr.tw/4mbHK4W
#Medsky #Rheumsky #Rheumatology
📄 Read the paper: acr.tw/47mkegj
ℹ️ See additional content and resources on this guideline at acr.tw/4mbHK4W
#Medsky #Rheumsky #Rheumatology
Reposted by Bethan Goulden
Great news! Excited to announce the date and location of ISOM/MOMS2026.
QEII centre, London, UK
7-8th December 2026
Save the date! Share with friends! Plan your trip!
#ISOMMOMS2026
QEII centre, London, UK
7-8th December 2026
Save the date! Share with friends! Plan your trip!
#ISOMMOMS2026
October 21, 2025 at 8:38 PM
Great news! Excited to announce the date and location of ISOM/MOMS2026.
QEII centre, London, UK
7-8th December 2026
Save the date! Share with friends! Plan your trip!
#ISOMMOMS2026
QEII centre, London, UK
7-8th December 2026
Save the date! Share with friends! Plan your trip!
#ISOMMOMS2026
Reposted by Bethan Goulden
Join us on October 29 for our upcoming webinar, “The Burning Question of Acetaminophen in Pregnancy.”
Open to both members and non-members — everyone is welcome!
🔗 Register here: sinaihealth.zoom.us/webinar/regi...
Open to both members and non-members — everyone is welcome!
🔗 Register here: sinaihealth.zoom.us/webinar/regi...
October 18, 2025 at 10:07 PM
Join us on October 29 for our upcoming webinar, “The Burning Question of Acetaminophen in Pregnancy.”
Open to both members and non-members — everyone is welcome!
🔗 Register here: sinaihealth.zoom.us/webinar/regi...
Open to both members and non-members — everyone is welcome!
🔗 Register here: sinaihealth.zoom.us/webinar/regi...
Reposted by Bethan Goulden
Happy World Menopause Day. Reminder that as well as the impact of menopause on physical and mental wellbeing. Menopause also seems to be an immune-ageing event www.qmul.ac.uk/media/news/2...
Hormone replacement therapy may help restore immunity in menopausal women
www.qmul.ac.uk
October 18, 2025 at 6:38 AM
Happy World Menopause Day. Reminder that as well as the impact of menopause on physical and mental wellbeing. Menopause also seems to be an immune-ageing event www.qmul.ac.uk/media/news/2...
Reposted by Bethan Goulden
I am very grateful to my funders the @vivensa.bsky.social and @bartscharity.bsky.social for funding this research through seed awards. More research is desperately needed to understand the impact of menopause on immunity and I hope more funders consider this as an important research area. #immunosky
October 9, 2025 at 10:25 AM
I am very grateful to my funders the @vivensa.bsky.social and @bartscharity.bsky.social for funding this research through seed awards. More research is desperately needed to understand the impact of menopause on immunity and I hope more funders consider this as an important research area. #immunosky
Reposted by Bethan Goulden
This study was an amazing Early Career researcher effort with Roel de Maeyer performing the functional monocyte assays, @oliviabracken.bsky.social performing the bioinformatic analysis, and my lovely lab member Justyna performing the Menopause analysis. I am very grateful for all their hard work.
October 9, 2025 at 10:23 AM
This study was an amazing Early Career researcher effort with Roel de Maeyer performing the functional monocyte assays, @oliviabracken.bsky.social performing the bioinformatic analysis, and my lovely lab member Justyna performing the Menopause analysis. I am very grateful for all their hard work.
Reposted by Bethan Goulden
Importantly the use of Hormone Replacement Therapy (HRT) in menopausal females kept their monocytes looking ‘young’ and they had improved phagocytosis as compared to age matched controls. Highlighting the potential immune benefits of HRT.
October 9, 2025 at 10:22 AM
Importantly the use of Hormone Replacement Therapy (HRT) in menopausal females kept their monocytes looking ‘young’ and they had improved phagocytosis as compared to age matched controls. Highlighting the potential immune benefits of HRT.
Reposted by Bethan Goulden
In this paper we demonstrate that there is an increase in inflammatory monocytes with altered proteome in post-menopausal females, which is not observed with age in males. Phagocytosis is significantly decreased in post-menopausal as compared to pre-menopausal females.
October 9, 2025 at 10:22 AM
In this paper we demonstrate that there is an increase in inflammatory monocytes with altered proteome in post-menopausal females, which is not observed with age in males. Phagocytosis is significantly decreased in post-menopausal as compared to pre-menopausal females.
Reposted by Bethan Goulden
I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function.
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy
Post-menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre-menopausal (< 40 years) females. Hormone Replace....
onlinelibrary.wiley.com
October 9, 2025 at 10:21 AM
I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function.
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Bethan Goulden
🌟 New MOMS Webinar Series! 🌟
Breathe and Think: Neuro & Respiratory insights for Midwives
📅 30th Sept 2025
🕡 6:30–8:00 pm (BST)
👉 Free to attend & available for 4 weeks after via obstetricmedic.org.uk
🔗 Register via QR code on poster!
#Midwifery #ObstetricMedicine #Neuro #Respiratory #MOMS
Breathe and Think: Neuro & Respiratory insights for Midwives
📅 30th Sept 2025
🕡 6:30–8:00 pm (BST)
👉 Free to attend & available for 4 weeks after via obstetricmedic.org.uk
🔗 Register via QR code on poster!
#Midwifery #ObstetricMedicine #Neuro #Respiratory #MOMS
September 21, 2025 at 9:39 PM
🌟 New MOMS Webinar Series! 🌟
Breathe and Think: Neuro & Respiratory insights for Midwives
📅 30th Sept 2025
🕡 6:30–8:00 pm (BST)
👉 Free to attend & available for 4 weeks after via obstetricmedic.org.uk
🔗 Register via QR code on poster!
#Midwifery #ObstetricMedicine #Neuro #Respiratory #MOMS
Breathe and Think: Neuro & Respiratory insights for Midwives
📅 30th Sept 2025
🕡 6:30–8:00 pm (BST)
👉 Free to attend & available for 4 weeks after via obstetricmedic.org.uk
🔗 Register via QR code on poster!
#Midwifery #ObstetricMedicine #Neuro #Respiratory #MOMS
Reposted by Bethan Goulden
💊 Paracetamol remains the drug of choice for pain and fever in pregnancy.
Read the joint statement from UKTIS, BMFMS and MOMS
🤰Clinical guidelines remain unchanged: maternal pain and fever should be treated appropriately.
uktis.org/wp-content/u...
Read the joint statement from UKTIS, BMFMS and MOMS
🤰Clinical guidelines remain unchanged: maternal pain and fever should be treated appropriately.
uktis.org/wp-content/u...
uktis.org
September 23, 2025 at 9:20 PM
💊 Paracetamol remains the drug of choice for pain and fever in pregnancy.
Read the joint statement from UKTIS, BMFMS and MOMS
🤰Clinical guidelines remain unchanged: maternal pain and fever should be treated appropriately.
uktis.org/wp-content/u...
Read the joint statement from UKTIS, BMFMS and MOMS
🤰Clinical guidelines remain unchanged: maternal pain and fever should be treated appropriately.
uktis.org/wp-content/u...
Reposted by Bethan Goulden
📢 Can I have a baby? 📢
Join on 16th Oct 2025, 7.30–9.00pm (UK time) to discuss:
👶 Fertility preservation
🧬 Preimplantation genetic testing
🤰 Surrogacy
Free to attend & available on-demand for 4 weeks!
Register 👉 www.obstetricmedic.org.uk
#Fertility #ObstetricMedicine #ReproductiveHealth
Join on 16th Oct 2025, 7.30–9.00pm (UK time) to discuss:
👶 Fertility preservation
🧬 Preimplantation genetic testing
🤰 Surrogacy
Free to attend & available on-demand for 4 weeks!
Register 👉 www.obstetricmedic.org.uk
#Fertility #ObstetricMedicine #ReproductiveHealth
September 27, 2025 at 10:50 AM
📢 Can I have a baby? 📢
Join on 16th Oct 2025, 7.30–9.00pm (UK time) to discuss:
👶 Fertility preservation
🧬 Preimplantation genetic testing
🤰 Surrogacy
Free to attend & available on-demand for 4 weeks!
Register 👉 www.obstetricmedic.org.uk
#Fertility #ObstetricMedicine #ReproductiveHealth
Join on 16th Oct 2025, 7.30–9.00pm (UK time) to discuss:
👶 Fertility preservation
🧬 Preimplantation genetic testing
🤰 Surrogacy
Free to attend & available on-demand for 4 weeks!
Register 👉 www.obstetricmedic.org.uk
#Fertility #ObstetricMedicine #ReproductiveHealth
Reposted by Bethan Goulden
Fertility clinics must end unproven treatments that don't help couples have babies
www.nice.org.uk/news/article...
www.nice.org.uk/news/article...
Fertility clinics must end unproven treatments that don't help couples have babies
www.nice.org.uk
September 11, 2025 at 7:33 PM
Fertility clinics must end unproven treatments that don't help couples have babies
www.nice.org.uk/news/article...
www.nice.org.uk/news/article...
Great not only to have the work we're doing on HLH included in today's conference for the release of the #MBRRACEUK report on UK maternal mortality, but to also see another presentation on this topic. Is HLH as rare as we think, or simply rarely diagnosed?
September 11, 2025 at 8:10 AM
Great not only to have the work we're doing on HLH included in today's conference for the release of the #MBRRACEUK report on UK maternal mortality, but to also see another presentation on this topic. Is HLH as rare as we think, or simply rarely diagnosed?
Reposted by Bethan Goulden
The first new UK-wide long-term scientific study of babies and child development in a quarter of a century will be led at UCL's @clscohorts.bsky.social by Profs Alisa Goodman, @drlisac.bsky.social and Pasco Fearon @uclpals.bsky.social @ioe.bsky.social @news.ukri.org www.ucl.ac.uk/news/2025/se...
September 9, 2025 at 1:51 PM
The first new UK-wide long-term scientific study of babies and child development in a quarter of a century will be led at UCL's @clscohorts.bsky.social by Profs Alisa Goodman, @drlisac.bsky.social and Pasco Fearon @uclpals.bsky.social @ioe.bsky.social @news.ukri.org www.ucl.ac.uk/news/2025/se...
⏰Final push - UK rheum doctors/nurses/physios/AHPs pleeeease take 5 minutes to complete this. I would particularly welcome thoughts from those practicing in Wales, Scotland or Northern Ireland who are currently under-represented in the respondents!
qualtrics.ucl.ac.uk/jfe/form/SV_...
qualtrics.ucl.ac.uk/jfe/form/SV_...
**Rheumatology doctors/nurses/physios in the UK**
This is a short survey to map current reproductive health support/advice available across rheum services in the UK. Please fill it in & share within your networks to help guide next steps/guidelines 📑
qualtrics.ucl.ac.uk/jfe/form/SV_...
This is a short survey to map current reproductive health support/advice available across rheum services in the UK. Please fill it in & share within your networks to help guide next steps/guidelines 📑
qualtrics.ucl.ac.uk/jfe/form/SV_...
Qualtrics Survey | Qualtrics Experience Management
The most powerful, simple and trusted way to gather experience data. Start your journey to experience management and try a free account today.
qualtrics.ucl.ac.uk
September 1, 2025 at 2:54 PM
⏰Final push - UK rheum doctors/nurses/physios/AHPs pleeeease take 5 minutes to complete this. I would particularly welcome thoughts from those practicing in Wales, Scotland or Northern Ireland who are currently under-represented in the respondents!
qualtrics.ucl.ac.uk/jfe/form/SV_...
qualtrics.ucl.ac.uk/jfe/form/SV_...
Reposted by Bethan Goulden
📝 Like Wordle but wish it involved plagues?
It's not quite the same -- there's no spelling just a series of clues in a similar feedback loop as Wordle -- but it's pretty cool! Complements of an anonymous med student on Reddit.
#IDSky #MedSky
www.plagdle.com
It's not quite the same -- there's no spelling just a series of clues in a similar feedback loop as Wordle -- but it's pretty cool! Complements of an anonymous med student on Reddit.
#IDSky #MedSky
www.plagdle.com
Plagdle - Daily Infectious Disease Puzzle Game
Test your medical knowledge! Guess the daily infectious disease based on symptoms, treatment, and characteristics. A new puzzle every day!
www.plagdle.com
August 31, 2025 at 6:46 PM
📝 Like Wordle but wish it involved plagues?
It's not quite the same -- there's no spelling just a series of clues in a similar feedback loop as Wordle -- but it's pretty cool! Complements of an anonymous med student on Reddit.
#IDSky #MedSky
www.plagdle.com
It's not quite the same -- there's no spelling just a series of clues in a similar feedback loop as Wordle -- but it's pretty cool! Complements of an anonymous med student on Reddit.
#IDSky #MedSky
www.plagdle.com
Reposted by Bethan Goulden
✨We’ve just launched our new guide to #vaccinations during #pregnancy!
Understand how immunity changes, which vaccines the NHS recommends, and how they protect both parent and baby during pregnancy and beyond.
Download a copy for trusted information: bit.ly/4fuRqVw
Understand how immunity changes, which vaccines the NHS recommends, and how they protect both parent and baby during pregnancy and beyond.
Download a copy for trusted information: bit.ly/4fuRqVw
August 6, 2025 at 10:16 AM
✨We’ve just launched our new guide to #vaccinations during #pregnancy!
Understand how immunity changes, which vaccines the NHS recommends, and how they protect both parent and baby during pregnancy and beyond.
Download a copy for trusted information: bit.ly/4fuRqVw
Understand how immunity changes, which vaccines the NHS recommends, and how they protect both parent and baby during pregnancy and beyond.
Download a copy for trusted information: bit.ly/4fuRqVw
Reposted by Bethan Goulden
**Rheumatology doctors/nurses/physios in the UK**
This is a short survey to map current reproductive health support/advice available across rheum services in the UK. Please fill it in & share within your networks to help guide next steps/guidelines 📑
qualtrics.ucl.ac.uk/jfe/form/SV_...
This is a short survey to map current reproductive health support/advice available across rheum services in the UK. Please fill it in & share within your networks to help guide next steps/guidelines 📑
qualtrics.ucl.ac.uk/jfe/form/SV_...
Qualtrics Survey | Qualtrics Experience Management
The most powerful, simple and trusted way to gather experience data. Start your journey to experience management and try a free account today.
qualtrics.ucl.ac.uk
July 29, 2025 at 7:31 AM
**Rheumatology doctors/nurses/physios in the UK**
This is a short survey to map current reproductive health support/advice available across rheum services in the UK. Please fill it in & share within your networks to help guide next steps/guidelines 📑
qualtrics.ucl.ac.uk/jfe/form/SV_...
This is a short survey to map current reproductive health support/advice available across rheum services in the UK. Please fill it in & share within your networks to help guide next steps/guidelines 📑
qualtrics.ucl.ac.uk/jfe/form/SV_...
Reposted by Bethan Goulden
New systematic review of pregnancy associated HLH
- 104 pregnancies
- commonest cause infections (EBV, CMV, HSV, parvo)
- followed by SLE, stills, lymphoma
- 4/14 tested has positive genetics
- 40% no known cause
onlinelibrary.wiley.com/doi/epdf/10....
1/6
- 104 pregnancies
- commonest cause infections (EBV, CMV, HSV, parvo)
- followed by SLE, stills, lymphoma
- 4/14 tested has positive genetics
- 40% no known cause
onlinelibrary.wiley.com/doi/epdf/10....
1/6
Hemophagocytic Lymphohistiocytosis in Pregnancy: A Systematic Review of Case Reports and Case Series
Aims Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening syndrome caused by excessive immune activation, leading to severe inflammation and multi-organ failure. While adult-onset HL...
onlinelibrary.wiley.com
July 29, 2025 at 7:34 AM
New systematic review of pregnancy associated HLH
- 104 pregnancies
- commonest cause infections (EBV, CMV, HSV, parvo)
- followed by SLE, stills, lymphoma
- 4/14 tested has positive genetics
- 40% no known cause
onlinelibrary.wiley.com/doi/epdf/10....
1/6
- 104 pregnancies
- commonest cause infections (EBV, CMV, HSV, parvo)
- followed by SLE, stills, lymphoma
- 4/14 tested has positive genetics
- 40% no known cause
onlinelibrary.wiley.com/doi/epdf/10....
1/6
Reposted by Bethan Goulden
obgyn.onlinelibrary.wiley.com/doi/epdf/10....
Very proud to be associated with this much needed guidance that will help reduce inequalities in care for women with cancer in pregnancy @melanienana1.bsky.social @bethangoulden.bsky.social @berniejenner.bsky.social
Very proud to be associated with this much needed guidance that will help reduce inequalities in care for women with cancer in pregnancy @melanienana1.bsky.social @bethangoulden.bsky.social @berniejenner.bsky.social
Cancer in pregnancy: FIGO Best practice advice and narrative review
You have to enable JavaScript in your browser's settings in order to use the eReader.
obgyn.onlinelibrary.wiley.com
July 24, 2025 at 2:19 PM
obgyn.onlinelibrary.wiley.com/doi/epdf/10....
Very proud to be associated with this much needed guidance that will help reduce inequalities in care for women with cancer in pregnancy @melanienana1.bsky.social @bethangoulden.bsky.social @berniejenner.bsky.social
Very proud to be associated with this much needed guidance that will help reduce inequalities in care for women with cancer in pregnancy @melanienana1.bsky.social @bethangoulden.bsky.social @berniejenner.bsky.social
New systematic review of pregnancy associated HLH
- 104 pregnancies
- commonest cause infections (EBV, CMV, HSV, parvo)
- followed by SLE, stills, lymphoma
- 4/14 tested has positive genetics
- 40% no known cause
onlinelibrary.wiley.com/doi/epdf/10....
1/6
- 104 pregnancies
- commonest cause infections (EBV, CMV, HSV, parvo)
- followed by SLE, stills, lymphoma
- 4/14 tested has positive genetics
- 40% no known cause
onlinelibrary.wiley.com/doi/epdf/10....
1/6
Hemophagocytic Lymphohistiocytosis in Pregnancy: A Systematic Review of Case Reports and Case Series
Aims Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening syndrome caused by excessive immune activation, leading to severe inflammation and multi-organ failure. While adult-onset HL...
onlinelibrary.wiley.com
July 29, 2025 at 7:34 AM
New systematic review of pregnancy associated HLH
- 104 pregnancies
- commonest cause infections (EBV, CMV, HSV, parvo)
- followed by SLE, stills, lymphoma
- 4/14 tested has positive genetics
- 40% no known cause
onlinelibrary.wiley.com/doi/epdf/10....
1/6
- 104 pregnancies
- commonest cause infections (EBV, CMV, HSV, parvo)
- followed by SLE, stills, lymphoma
- 4/14 tested has positive genetics
- 40% no known cause
onlinelibrary.wiley.com/doi/epdf/10....
1/6
**Rheumatology doctors/nurses/physios in the UK**
This is a short survey to map current reproductive health support/advice available across rheum services in the UK. Please fill it in & share within your networks to help guide next steps/guidelines 📑
qualtrics.ucl.ac.uk/jfe/form/SV_...
This is a short survey to map current reproductive health support/advice available across rheum services in the UK. Please fill it in & share within your networks to help guide next steps/guidelines 📑
qualtrics.ucl.ac.uk/jfe/form/SV_...
Qualtrics Survey | Qualtrics Experience Management
The most powerful, simple and trusted way to gather experience data. Start your journey to experience management and try a free account today.
qualtrics.ucl.ac.uk
July 29, 2025 at 7:31 AM
**Rheumatology doctors/nurses/physios in the UK**
This is a short survey to map current reproductive health support/advice available across rheum services in the UK. Please fill it in & share within your networks to help guide next steps/guidelines 📑
qualtrics.ucl.ac.uk/jfe/form/SV_...
This is a short survey to map current reproductive health support/advice available across rheum services in the UK. Please fill it in & share within your networks to help guide next steps/guidelines 📑
qualtrics.ucl.ac.uk/jfe/form/SV_...