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JAMA Internal Medicine
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JAMA Internal Medicine is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

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This case report describes a woman in her 60s with sequential type I Kounis syndrome and cholecystocardial syndrome, leading to dynamic, reversible electrocardiography changes mimicking acute coronary syndrome. ja.ma/3Yczya1
December 25, 2025 at 1:00 PM
The numbers are in.

This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025, and did other readers agree?

🔗 ja.ma/49qQLCT
December 25, 2025 at 12:00 PM
💬 Editorial: Most US adults were less comfortable with the use of income or zip code vs race when incorporated into clinical algorithms, despite increasing shifts toward race-neutral tools in #RiskPrediction.

ja.ma/49rqswj
December 24, 2025 at 2:00 PM
Most US adults preferred that clinicians use all available information, including race, in clinical algorithms, but discomfort was greater if race was used without explanation or when income or zip code was included. ja.ma/48RAarI
December 24, 2025 at 1:00 PM
The numbers are in.

The numbers are in. This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025 -- and did other readers agree?

🔗 ja.ma/3KWyCUf
December 23, 2025 at 4:30 PM
💬 Editorial: #Benzodiazepine use during #pregnancy was associated with increased risks of preterm birth, spontaneous and elective abortion, and possibly small for gestational age, though the absolute risks were low.

ja.ma/4jk5piQ
December 23, 2025 at 2:00 PM
#Benzodiazepine use during #pregnancy was associated with increased risks of preterm birth, spontaneous and elective abortion, and possibly small for gestational age; risk for stillbirth was not increased. ja.ma/45hUct1
December 23, 2025 at 1:00 PM
Higher-valent #pneumococcal vaccines, PCV20 and PCV21, address shifting serotype patterns in adult invasive pneumococcal disease serotypes; vaccine choice depends on regional strain prevalence. ja.ma/4peMZBj
December 23, 2025 at 12:00 PM
Over 4 years, nearly 1 in 6 US adults incurred out-of-pocket health care costs exceeding 10% of family income, with higher risks among those with low income, uninsurance, chronic disease, or hospitalization. ja.ma/49u6dNF
December 22, 2025 at 6:46 PM
Among adults hospitalized for community-onset #sepsis, broad-spectrum #antibiotic de-escalation at day 4 resulted in similar mortality, fewer antibiotic days, and shorter hospitalizations vs continued therapy. ja.ma/4p7ffG0
December 22, 2025 at 6:42 PM
Viewpoint: The Fifth Amendment ensures due process protections for acute medical care of immigration detainees; differential treatment based on custody is not justified. ja.ma/4pHWn1k
December 22, 2025 at 1:00 PM
This case report describes a patient in their 50s with spontaneous chest tightness and palpitations. ja.ma/4arbAzc
December 21, 2025 at 1:00 PM
This case report describes a patient in their 50s with spontaneous chest tightness and palpitations. ja.ma/4p8woil
December 21, 2025 at 1:00 PM
Hospice benefits in ACA Marketplace plans require substantial cost-sharing, with median deductibles of $4000 and median coinsurance of 20%, potentially impacting access for low-income enrollees. ja.ma/4p3TPtm
December 20, 2025 at 1:00 PM
Viewpoint: Physician roles will adapt as patients increasingly use #GenAI for medical research, diagnosis, and clinical interpretation.

ja.ma/4aZe6wH
December 19, 2025 at 1:00 PM
PREVENT risk equations identify fewer adults aged 40–59 as aspirin-eligible for primary ASCVD prevention than PCEs. ja.ma/44vBhLg
December 18, 2025 at 1:00 PM
Editor's Note: Defining obesity by clinical outcomes, not just body size, may advance care and target those at greatest health risk. ja.ma/4p3XirV
December 17, 2025 at 2:00 PM
Clinical obesity, as newly defined by excess adiposity and organ dysfunction, was linked to greater all-cause and cause-specific mortality risk in the UK Biobank cohort. ja.ma/44SsQd9
December 17, 2025 at 1:00 PM
This Teachable Moment describes a patient in their 60s with severe alcohol use disorder and alcohol-induced cirrhosis complicated by ascites who presented with an altered mental status. ja.ma/4iV4EMI
December 16, 2025 at 1:00 PM
During extreme heat days, mortality rates were higher in nursing homes without air conditioning vs those with air conditioning, supporting universal AC mandates. ja.ma/4j2SSAe
December 15, 2025 at 4:30 PM
Only 4 US states comprehensively regulate IV hydration spa governance, prescriber credentials, dispensing, and compounding practices. ja.ma/3MCTJLJ
December 15, 2025 at 1:00 PM
Participation in the New York State medical cannabis program was associated with a significant reduction in prescription opioid receipt over 18 months among adults with chronic pain.

ja.ma/3MERmIa
December 14, 2025 at 4:00 PM
Participation in the New York State medical cannabis program was associated with a significant reduction in prescription opioid receipt over 18 months among adults with chronic pain.

ja.ma/4pxMAL5
December 14, 2025 at 2:00 PM
Viewpoint: Menopause care should extend beyond hormone therapy, emphasizing individualized care, clinician training, and evidence-based management. ja.ma/4sc3hxJ
December 14, 2025 at 1:00 PM
Criteria-independent genetic testing identified pathogenic variants in 3.1% of women without a history of #BreastCancer, including many lacking common risk factors.

ja.ma/3YrE6Jy
December 13, 2025 at 4:00 PM