First-year over-the-counter naloxone sales showed limited uptake and did not effectively bridge gaps from pharmacy or distribution programs, likely due to high prices. ja.ma/4ogyhcJ

From 2017 to 2023, #Medicare Advantage beneficiaries saw disproportionately greater increases in hospital length of stay compared to traditional Medicare, particularly for discharges to skilled nursing facilities. ja.ma/4qSkafY

This Review explores the factors that predispose Hispanic/Latino patients to metabolic dysfunction–associated steatotic liver disease and metabolic dysfunction–associated steatohepatitis. ja.ma/3JD2ww6

JAMA Internal Medicine is looking for research on how AI is transforming patient care in areas such as clinical outcomes, diagnosis, system redesign, ethics, equity, and women’s health.

🔗 Learn more about submission criteria: ja.ma/3KJBqng

This Guide to Statistics and Methods provides an overview of the active comparator, new user design and the use of propensity score matching. ja.ma/47IsMx8

The Mighty-Heart trial found mobile integrated health offered no overall benefit over care coordination alone for #HeartFailure patients' health status or 30-day readmissions, but younger patients showed potential health improvements. ja.ma/4p0lpI9

Editor’s Note: Schwartz et al show risk-based provider contracts in Medicare Advantage do not consistently alter care use or low-value service rates. ja.ma/4qY9NYc

Voluntary transition to upside-only or 2-sided risk payment contracts in Medicare Advantage was not associated with consistent changes in health care utilization or low-value service use. ja.ma/4nJcWs6

A Singapore-based RCT found that a single mailed reminder is as effective as more complex behavioral interventions for increasing mammogram uptake among overdue repeat screeners. ja.ma/43fA9KY

Assoc. Editor Giselle Corbie, MD, MSc, and author Lynda Powell, PhD, discuss strategies for supporting lasting lifestyle changes and long-term outcomes for patients with metabolic syndrome.

#AHA25 @ahascience.bsky.social

🎧 Listen now: ja.ma/3WMJTc0

A 6-month habit-based group lifestyle intervention added to routine education and activity monitoring improved the proportion of patients with sustained metabolic syndrome remission.

#AHA25 @ahascience.bsky.social

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A randomized clinical trial published in JAMA found that patients with AF who consumed caffeinated coffee had a lower risk of recurrent AF or atrial flutter compared with those who abstained.

#AHA25 #AFib @ahascience.bsky.social

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📊 Research Summary from @jama.com: Adults with #AFib who drank at least one cup of caffeinated coffee daily after successful cardioversion had a lower risk of recurrence than those who abstained from coffee and caffeine.

#AHA25 @ahascience.bsky.social

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From @jama.com: Patients with #AFib who continued their usual caffeinated coffee intake after cardioversion experienced less recurrence of AF or atrial flutter compared to those who abstained from coffee and caffeine.

#AHA25 @ahascience.bsky.social

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#HormoneTherapy reduces vasomotor symptoms w/o increasing #cardiovascular risk in postmenopausal women aged 50 to 59, but raises cardiovascular risk in those over 70, finds this secondary analysis of 2 RCTs.

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From @jama.com: Liberal transfusion after major surgery did not reduce death or major cardiac event rates compared to restrictive thresholds in high-risk patients.

#AHA25 @ahascience.bsky.social

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From @jama.com: Among people with PAD and no #diabetes, metformin treatment for 6 months did not result in improvements in walking ability or secondary outcomes vs placebo.

#AHA25 @ahascience.bsky.social

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Special Communication: Doubling of early-onset cancer incidence since 1992 in US adults <50 reflects increased diagnosis; mortality remains stable or declines. ja.ma/3WDtFls

💬 @jama.com Editorial: #SGLT2 inhibitor treatment benefits extend to people with CKD and low albuminuria, as well as those with advanced #KidneyDisease, supporting wider use.

#KidneyWk @asnkidney.bsky.social

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From @jama.com: #SGLT2 inhibitors slow kidney decline consistently across CKD severity and albuminuria range, supporting their routine use for kidney health.

#KidneyWK @asnkidney.bsky.social

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From <a href="https://bsky.app/profile/did:plc:q5ogl3twkcqyhvz4zebonw3z" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky-mention">@jama.com: Among more than 800 000 CKD-PC participants, discordance between cystatin C and creatinine eGFR values was associated with increased risk of death, cardiovascular events, and kidney failure.

#KidneyWK <a href="https://bsky.app/profile/did:plc:7o2r67qqxflcit2osd2wu7ti" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky-mention">@asnkidney.bsky.social

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💬 Editorial: Estrella et al show that integrated cystatin C and creatinine measurements improve CKD assessment compared to single-marker estimates.

#KidneyWK

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💬 @jama.com Editorial: The LIBERATE-D trial shows conservative dialysis—guided by A-E-I-O-U indications and asking "Why"—promotes earlier kidney recovery and fewer dialysis sessions in AKI.

#KidneyWK @asnkidney.bsky.social

ja.ma/4hOkM1W

From @jama.com: In stable AKI patients, indication-based dialysis enabled faster liberation from dialysis and reduced health care resource use compared to conventional thrice-weekly treatment.

#KidneyWK @asnkidney.bsky.social

ja.ma/43Zf33H

Among Hispanic and Latino adults receiving in-center hemodialysis, a culturally tailored community health worker intervention modestly reduced interdialytic weight gain and improved adherence and patient activation compared to standard care.

#KidneyWK ja.ma/49AwhYP