JAMA Internal Medicine
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JAMA Internal Medicine
@jamainternalmed.com
JAMA Internal Medicine is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

🌐 JAMAInternalMed.com
💬 Editorial: Proposals to apply clinician-style licensure to #AI tools may allow adaptive oversight as AI models grow more complex. Implementation challenges include defining responsible parties and ensuring adequate regulatory expertise.

ja.ma/4raFQUZ
November 22, 2025 at 3:00 PM
💬 Viewpoint: The #Medicare hospice benefit's limited custodial care burden on families highlights the need for reform to meet the growing caregiving demands of end-of-life care.

ja.ma/47UCwFN
November 22, 2025 at 1:00 PM
This case report describes a woman in her 50s who presented for evaluation of fatigue and exertional dyspnea. ja.ma/4ifkDoP
November 21, 2025 at 3:00 PM
💬 Viewpoint: An external medical review board for compassionate release could reduce the incarceration of terminally ill patients by focusing on medical criteria, addressing ethical concerns, and promoting dignified end-of-life care.

ja.ma/4a18FNd
November 21, 2025 at 1:00 PM
💡Clinical Insight: New ASAM guidelines for Benzodiazepine advise gradual dose reductions, flexible timelines, and frequent reassessment for withdrawal symptoms; dose reductions, rather than discontinuation, may be suitable for high-risk patients.

ja.ma/3KcENTC
November 20, 2025 at 3:00 PM
In a patient with squamous cell carcinoma receiving sintilimab therapy, symptoms and ECG findings indicated immune checkpoint inhibitor-induced myocarditis rather than STEMI. ja.ma/4nZeQVn
November 20, 2025 at 1:00 PM
The Competitive Generic Therapy pathway led to 83.5% of approved generics launching within 75 days, with a median drug price reduction of 18% after market entry. ja.ma/3K5nl3j
November 19, 2025 at 3:00 PM
This case report describes a man in his 60s with South African flag sign on electrocardiography. ja.ma/3K3JZcj
November 19, 2025 at 1:00 PM
Most countries hosting trials for FDA-approved medicines do not gain timely physical access to those treatments, especially low- and middle-income countries, with only 24% accessible in all trial locations at 5 years. ja.ma/47Xoge3
November 18, 2025 at 3:00 PM
A woman in her 50s with #obesity, #diabetes, and #hypertension was treated for mild autonomous cortisol secretion caused by an adrenal nodule and improved following an adrenalectomy. Learn more in this Teachable Moment: ja.ma/445srU2
November 18, 2025 at 1:00 PM
Female individuals with stage 5 #ChronicKidneyDisease show greater excess mortality than males, especially before age 55, with the female survival advantage found in the general population absent or reversed in this cohort. ja.ma/4i4tTvz
November 17, 2025 at 5:00 PM
Between February and August 2025, 1 in 30 NIH-funded clinical trials lost grant funding, affecting over 74,000 participants, with disproportionate impact on prevention, infectious disease, and behavioral trials. ja.ma/4i4tSYx
November 17, 2025 at 4:30 PM
First-year over-the-counter naloxone sales showed limited uptake and did not effectively bridge gaps from pharmacy or distribution programs, likely due to high prices. ja.ma/4ogyhcJ
November 16, 2025 at 1:00 PM
From 2017 to 2023, #Medicare Advantage beneficiaries saw disproportionately greater increases in hospital length of stay compared to traditional Medicare, particularly for discharges to skilled nursing facilities. ja.ma/4qSkafY
November 15, 2025 at 1:00 PM
This Review explores the factors that predispose Hispanic/Latino patients to metabolic dysfunction–associated steatotic liver disease and metabolic dysfunction–associated steatohepatitis. ja.ma/3JD2ww6
November 13, 2025 at 1:00 PM
JAMA Internal Medicine is looking for research on how AI is transforming patient care in areas such as clinical outcomes, diagnosis, system redesign, ethics, equity, and women’s health.

🔗 Learn more about submission criteria: ja.ma/3KJBqng
November 13, 2025 at 12:00 AM
This Guide to Statistics and Methods provides an overview of the active comparator, new user design and the use of propensity score matching. ja.ma/47IsMx8
November 12, 2025 at 2:00 PM
The Mighty-Heart trial found mobile integrated health offered no overall benefit over care coordination alone for #HeartFailure patients' health status or 30-day readmissions, but younger patients showed potential health improvements. ja.ma/4p0lpI9
November 12, 2025 at 1:00 PM
Editor’s Note: Schwartz et al show risk-based provider contracts in Medicare Advantage do not consistently alter care use or low-value service rates. ja.ma/4qY9NYc
November 11, 2025 at 3:30 PM
Voluntary transition to upside-only or 2-sided risk payment contracts in Medicare Advantage was not associated with consistent changes in health care utilization or low-value service use. ja.ma/4nJcWs6
November 11, 2025 at 3:00 PM
A Singapore-based RCT found that a single mailed reminder is as effective as more complex behavioral interventions for increasing mammogram uptake among overdue repeat screeners. ja.ma/43fA9KY
November 10, 2025 at 4:30 PM
Assoc. Editor Giselle Corbie, MD, MSc, and author Lynda Powell, PhD, discuss strategies for supporting lasting lifestyle changes and long-term outcomes for patients with metabolic syndrome.

#AHA25 @ahascience.bsky.social

🎧 Listen now: ja.ma/3WMJTc0
November 9, 2025 at 11:41 PM
Reposted by JAMA Internal Medicine
In this #AHA25 edition of the JAMA Editor’s Summary podcast, Gregory Curfman, MD, Philip Greenland, MD, and Robert Bonow, MD, MS, review key JAMA Network articles, including:

➡️ Coffee and #AFib,
➡️ DASH-patterned groceries,
➡️ Oral PCSK9 inhibitor enlicitide, and more.

🎧 Listen now: ja.ma/47MpAAj
November 9, 2025 at 11:35 PM
Reposted by JAMA Internal Medicine
💾 Save this thread! Check out these key findings from today's JAMA, @jamacardiology.com, @jamainternalmed.com, and
@jamanetworkopen.com presentations at #AHA25. 🧵

Adding coronary CT angiography to traditional risk scores modestly improved prediction of first coronary events. ja.ma/4oyzvko
November 9, 2025 at 11:20 PM
A 6-month habit-based group lifestyle intervention added to routine education and activity monitoring improved the proportion of patients with sustained metabolic syndrome remission.

#AHA25 @ahascience.bsky.social

ja.ma/4oYXnx9
November 9, 2025 at 10:30 PM