Dr Emma S Chambers
@emmaschambers.bsky.social
Senior Lecturer in Immunology based at Blizard Institute, QMUL. My research focussed on life course immunology and the influence of age and sex, and life-course events such as menopause on the immune system in health and disease.
Pinned
Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy
Post-menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre-menopausal (< 40 years) females. Hormone Replace....
onlinelibrary.wiley.com
I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function.
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
An exciting programme of talks today. Come and see my poster (17) about menopause as an immune ageing event.
Today we meet face to face for the first time!
October 23, 2025 at 8:54 AM
An exciting programme of talks today. Come and see my poster (17) about menopause as an immune ageing event.
Reposted by Dr Emma S Chambers
This #WorldMenopauseDay we're proud to talk about how we supported innovative research into menopause and women's immunity - led by @emmaschambers.bsky.social at the @blizardinstitute.bsky.social
@qmul.bsky.social
https://bit.ly/492IYeG
@qmul.bsky.social
https://bit.ly/492IYeG
Hormone replacement therapy may help restore immunity in menopausal women
https://www.qmul.ac.uk
www.qmul.ac.uk
October 18, 2025 at 1:43 PM
This #WorldMenopauseDay we're proud to talk about how we supported innovative research into menopause and women's immunity - led by @emmaschambers.bsky.social at the @blizardinstitute.bsky.social
@qmul.bsky.social
https://bit.ly/492IYeG
@qmul.bsky.social
https://bit.ly/492IYeG
Happy World Menopause Day. Reminder that as well as the impact of menopause on physical and mental wellbeing. Menopause also seems to be an immune-ageing event www.qmul.ac.uk/media/news/2...
Hormone replacement therapy may help restore immunity in menopausal women
www.qmul.ac.uk
October 18, 2025 at 6:38 AM
Happy World Menopause Day. Reminder that as well as the impact of menopause on physical and mental wellbeing. Menopause also seems to be an immune-ageing event www.qmul.ac.uk/media/news/2...
Reposted by Dr Emma S Chambers
Surprisingly, it is not yet obvious to all researchers and funding agencies that sex and gender matter in research, and should be recorded and addressed properly. So we wrote it authors.elsevier.com/c/1lxSmbah1w...
authors.elsevier.com
October 15, 2025 at 3:24 PM
Surprisingly, it is not yet obvious to all researchers and funding agencies that sex and gender matter in research, and should be recorded and addressed properly. So we wrote it authors.elsevier.com/c/1lxSmbah1w...
Reposted by Dr Emma S Chambers
Hormone replacement therapy helps restore immune function in menopausal women, reducing inflammaging and preserving monocyte function. open-access
onlinelibrary.wiley.com/doi/10.1111/...
Extends what I previously summarized from immune system clocks
erictopol.substack.com/p/new-anti-a...
onlinelibrary.wiley.com/doi/10.1111/...
Extends what I previously summarized from immune system clocks
erictopol.substack.com/p/new-anti-a...
October 9, 2025 at 10:45 PM
Hormone replacement therapy helps restore immune function in menopausal women, reducing inflammaging and preserving monocyte function. open-access
onlinelibrary.wiley.com/doi/10.1111/...
Extends what I previously summarized from immune system clocks
erictopol.substack.com/p/new-anti-a...
onlinelibrary.wiley.com/doi/10.1111/...
Extends what I previously summarized from immune system clocks
erictopol.substack.com/p/new-anti-a...
Reposted by Dr Emma S Chambers
New paper alert #immunosky 🚨
What happens to our immune systems as we get older? What happens after the menopause? Turns out monocytes are actually quite important in their own right!
Check out our paper in Aging Cell now:
onlinelibrary.wiley.com/doi/10.1111/...
What happens to our immune systems as we get older? What happens after the menopause? Turns out monocytes are actually quite important in their own right!
Check out our paper in Aging Cell now:
onlinelibrary.wiley.com/doi/10.1111/...
Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy
Post-menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre-menopausal (< 40 years) females. Hormone Replace...
onlinelibrary.wiley.com
October 9, 2025 at 2:36 PM
New paper alert #immunosky 🚨
What happens to our immune systems as we get older? What happens after the menopause? Turns out monocytes are actually quite important in their own right!
Check out our paper in Aging Cell now:
onlinelibrary.wiley.com/doi/10.1111/...
What happens to our immune systems as we get older? What happens after the menopause? Turns out monocytes are actually quite important in their own right!
Check out our paper in Aging Cell now:
onlinelibrary.wiley.com/doi/10.1111/...
I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function.
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy
Post-menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre-menopausal (< 40 years) females. Hormone Replace....
onlinelibrary.wiley.com
October 9, 2025 at 10:21 AM
I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function.
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
This afternoon I am speaking at @emds2025.bsky.social. Chatting monocytes, ageing and menopause :) Looking forward to an exciting meeting
September 16, 2025 at 7:56 AM
This afternoon I am speaking at @emds2025.bsky.social. Chatting monocytes, ageing and menopause :) Looking forward to an exciting meeting
Reposted by Dr Emma S Chambers
📣 Abstract submissions for #BSI25 are CLOSING SOON!
Don't miss your chance to share your research — submit today.
🗓️Deadline: Midnight, Weds 3 Sept
🔗Submit here: bit.ly/3UfF6i5
Don't miss your chance to share your research — submit today.
🗓️Deadline: Midnight, Weds 3 Sept
🔗Submit here: bit.ly/3UfF6i5
September 1, 2025 at 2:19 PM
📣 Abstract submissions for #BSI25 are CLOSING SOON!
Don't miss your chance to share your research — submit today.
🗓️Deadline: Midnight, Weds 3 Sept
🔗Submit here: bit.ly/3UfF6i5
Don't miss your chance to share your research — submit today.
🗓️Deadline: Midnight, Weds 3 Sept
🔗Submit here: bit.ly/3UfF6i5
Reposted by Dr Emma S Chambers
I am recruiting for a postdoc that wants to work on an exciting project on gut macrophages, TGFb signalling, and colon cancer! Please see the link for details - elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Postdoctoral Research Associate
We are looking for a talented and enthusiastic postdoctoral researcher to join the Shaw lab to investigate identify the regulatory function of NRROS/LRRC33 in gastrointestinal macrophage development a...
elxw.fa.em3.oraclecloud.com
August 12, 2025 at 2:56 PM
I am recruiting for a postdoc that wants to work on an exciting project on gut macrophages, TGFb signalling, and colon cancer! Please see the link for details - elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Reposted by Dr Emma S Chambers
New output from the CELLO Network. Article highlighting how metabolic dysfunction underpins ageing and disease.
Read the full open-access article 👉 link.springer.com/article/10.1...
#Ageing #Metabolism #CellBiology #SystemsBiology
Read the full open-access article 👉 link.springer.com/article/10.1...
#Ageing #Metabolism #CellBiology #SystemsBiology
June 23, 2025 at 1:54 PM
New output from the CELLO Network. Article highlighting how metabolic dysfunction underpins ageing and disease.
Read the full open-access article 👉 link.springer.com/article/10.1...
#Ageing #Metabolism #CellBiology #SystemsBiology
Read the full open-access article 👉 link.springer.com/article/10.1...
#Ageing #Metabolism #CellBiology #SystemsBiology
You get to listen to me talk about menopause and immunity :)
🚨 Early bird registration for our annual meeting ends this Wednesday - grab your tickets NOW! 🐦🎟️
Join us for: 'Diversity in Immunology'
🗓️ 11th July
📍Holiday Inn - Brentford Lock (new venue!)
Link to register: www.immunology.org/events/diver...
& check out our final speakers line-up! 🤩
#LIG2025
Join us for: 'Diversity in Immunology'
🗓️ 11th July
📍Holiday Inn - Brentford Lock (new venue!)
Link to register: www.immunology.org/events/diver...
& check out our final speakers line-up! 🤩
#LIG2025
June 23, 2025 at 9:06 PM
You get to listen to me talk about menopause and immunity :)
Reposted by Dr Emma S Chambers
GET YOUR APPLICATION IN NOW! Couldn’t recommend this lab more #sciencebffs ♥️
🚨 The Menon lab is hiring a postdoc!
Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases
@ukri.org @lydiabeckeriii.bsky.social
Please help spread the word #ImmunoSky
www.jobs.manchester.ac.uk/Job/JobDetai...
Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases
@ukri.org @lydiabeckeriii.bsky.social
Please help spread the word #ImmunoSky
www.jobs.manchester.ac.uk/Job/JobDetai...
Research Associate in Mucosal Immunology :Manchester
www.jobs.manchester.ac.uk
June 20, 2025 at 3:40 PM
GET YOUR APPLICATION IN NOW! Couldn’t recommend this lab more #sciencebffs ♥️
Reposted by Dr Emma S Chambers
Come join us this fall in Paris
Join the 1st EFIS Sex Differences in Immunity Congress – October 23, 2025 @pasteur.fr @sexdiffimmunity.bsky.social Registration link lnkd.in/emerimQc abstracts welcome from all researchers, scientists, clinicians #immunosky
May 13, 2025 at 4:30 AM
Come join us this fall in Paris
Reposted by Dr Emma S Chambers
Who's ready for another @thestemvillage.bsky.social Immunology Seminar Series? If you haven't seen these before, we invite LGBTQ+ immunologists to present online to the wider immunology community. If you'd like to present or attend, please drop a mention below #immunosky 🧪 #academicsky
April 24, 2025 at 11:04 AM
Who's ready for another @thestemvillage.bsky.social Immunology Seminar Series? If you haven't seen these before, we invite LGBTQ+ immunologists to present online to the wider immunology community. If you'd like to present or attend, please drop a mention below #immunosky 🧪 #academicsky
If you have wondered how age, sex and even the menopause influences monocyte phenotype and function. Then our new preprint is for you www.biorxiv.org/content/10.1...
Age-associated inflammatory monocytes are increased in menopausal females and reversed by Hormone Replacement Therapy
Biological sex is a crucial, but poorly understood variable in age-related susceptibility to infections and chronic inflammation, inflammageing. Monocytes are important immune cells responsible for in...
www.biorxiv.org
April 2, 2025 at 7:01 AM
If you have wondered how age, sex and even the menopause influences monocyte phenotype and function. Then our new preprint is for you www.biorxiv.org/content/10.1...
Reposted by Dr Emma S Chambers
Great coverage of the recent JEM paper by @hlpeks.bsky.social, @emmaschambers.bsky.social, @bcellsrosser.bsky.social, Coziana Ciurtin, and colleagues. See the original paper here: rupress.org/jem/article/...
March 26, 2025 at 1:28 PM
Great coverage of the recent JEM paper by @hlpeks.bsky.social, @emmaschambers.bsky.social, @bcellsrosser.bsky.social, Coziana Ciurtin, and colleagues. See the original paper here: rupress.org/jem/article/...
Super excited to have contributed to this great paper led by @bcellsrosser.bsky.social @arrdept-ucldom.bsky.social showing that Oestrogen influences B cell class switching. rupress.org/jem/article/...
Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes | Journal of Experimental Medicine | Rockefeller University Press
Sex hormones and chromosomes work in tandem to impact immune responses, with estrogen influencing class-switched memory B cell frequency exclusively in ind
rupress.org
March 25, 2025 at 2:45 PM
Super excited to have contributed to this great paper led by @bcellsrosser.bsky.social @arrdept-ucldom.bsky.social showing that Oestrogen influences B cell class switching. rupress.org/jem/article/...
Reposted by Dr Emma S Chambers
We have a new PhD position open in the lab! Interested in the intersection between cell mechanics and protein metabolism in scar formation, then have a look. tinyurl.com/4s7wduhu
Dissecting the role of lysosomal exocytosis in keloid scar pathogenesis at Queen Mary University of London on FindAPhD.com
PhD Project - Dissecting the role of lysosomal exocytosis in keloid scar pathogenesis at Queen Mary University of London, listed on FindAPhD.com
tinyurl.com
March 18, 2025 at 7:43 PM
We have a new PhD position open in the lab! Interested in the intersection between cell mechanics and protein metabolism in scar formation, then have a look. tinyurl.com/4s7wduhu
I had a lovely trip to my daughter's class today, to tell them all about our biological army, the immune system, for science week. I got such lovely thank you cards from the class :)
March 14, 2025 at 7:42 PM
I had a lovely trip to my daughter's class today, to tell them all about our biological army, the immune system, for science week. I got such lovely thank you cards from the class :)
I made myself an inspirational mug out of some recent grant feedback
January 24, 2025 at 9:05 AM
I made myself an inspirational mug out of some recent grant feedback
Reposted by Dr Emma S Chambers
Menopause:
Time to increase funding for study of a life stage experienced by half of humanity
www.nature.com/articles/d41...
Emerging therapies to prolong ovarian life and revisiting hormone replacement therapy could change women’s health
@lynnepeeps.bsky.social
www.nature.com/articles/d41...
Time to increase funding for study of a life stage experienced by half of humanity
www.nature.com/articles/d41...
Emerging therapies to prolong ovarian life and revisiting hormone replacement therapy could change women’s health
@lynnepeeps.bsky.social
www.nature.com/articles/d41...
January 22, 2025 at 7:16 PM
Menopause:
Time to increase funding for study of a life stage experienced by half of humanity
www.nature.com/articles/d41...
Emerging therapies to prolong ovarian life and revisiting hormone replacement therapy could change women’s health
@lynnepeeps.bsky.social
www.nature.com/articles/d41...
Time to increase funding for study of a life stage experienced by half of humanity
www.nature.com/articles/d41...
Emerging therapies to prolong ovarian life and revisiting hormone replacement therapy could change women’s health
@lynnepeeps.bsky.social
www.nature.com/articles/d41...
Reposted by Dr Emma S Chambers
We are super excited to share our newest publication on modelling immune responses in human skin! Hats off to the amazing work of Sarah Hindle during her PhD and all our collaborators!
@emmaschambers.bsky.social doi.org/10.1002/advs...
@emmaschambers.bsky.social doi.org/10.1002/advs...
Replicating Dynamic Immune Responses at Single‐Cell Resolution within a Microfluidic Human Skin Equivalent
This study describes the development of a vascularized microfluidic skin equivalent, which supports the delivery of circulating immune cells and replication of dynamic inflammatory responses. Single-...
doi.org
January 22, 2025 at 11:36 AM
We are super excited to share our newest publication on modelling immune responses in human skin! Hats off to the amazing work of Sarah Hindle during her PhD and all our collaborators!
@emmaschambers.bsky.social doi.org/10.1002/advs...
@emmaschambers.bsky.social doi.org/10.1002/advs...
Reposted by Dr Emma S Chambers
🚨 The Menon lab is hiring a postdoc!
Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases @ukri.org @lydiabeckeriii.bsky.social
Please help spread the word #ImmunoSky
www.jobs.manchester.ac.uk/Job/JobDetai...
Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases @ukri.org @lydiabeckeriii.bsky.social
Please help spread the word #ImmunoSky
www.jobs.manchester.ac.uk/Job/JobDetai...
Research Associate in Mucosal Immunology :Manchester
www.jobs.manchester.ac.uk
January 16, 2025 at 6:40 PM
🚨 The Menon lab is hiring a postdoc!
Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases @ukri.org @lydiabeckeriii.bsky.social
Please help spread the word #ImmunoSky
www.jobs.manchester.ac.uk/Job/JobDetai...
Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases @ukri.org @lydiabeckeriii.bsky.social
Please help spread the word #ImmunoSky
www.jobs.manchester.ac.uk/Job/JobDetai...