Roel De Maeyer
@roeldemaeyer.bsky.social
Immunology, inflammation and ageing
Reposted by Roel De Maeyer
Menopause reshapes women’s immune systems, leaving them vulnerable to infection. A new study has shown that HRT may help reverse these changes and boost immune health. https://www.ndorms.ox.ac.uk/news/hormone-therapy-may-help-restore-immunity-in-menopausal-women
October 22, 2025 at 1:42 PM
Menopause reshapes women’s immune systems, leaving them vulnerable to infection. A new study has shown that HRT may help reverse these changes and boost immune health. https://www.ndorms.ox.ac.uk/news/hormone-therapy-may-help-restore-immunity-in-menopausal-women
Reposted by Roel De Maeyer
It's #MenopauseAwarenessDay! Our new study exploring why women’s immune defences weaken after menopause offers some hope - suggesting that hormone replacement therapy (HRT) not only relieves symptoms, but those taking it had healthier immune systems in later life. https://f.mtr.cool/abqkylmndg
October 18, 2025 at 9:30 AM
It's #MenopauseAwarenessDay! Our new study exploring why women’s immune defences weaken after menopause offers some hope - suggesting that hormone replacement therapy (HRT) not only relieves symptoms, but those taking it had healthier immune systems in later life. https://f.mtr.cool/abqkylmndg
Reposted by Roel De Maeyer
Hormone replacement therapy helps restore immune function in menopausal women, reducing inflammaging and preserving monocyte function. open-access
onlinelibrary.wiley.com/doi/10.1111/...
Extends what I previously summarized from immune system clocks
erictopol.substack.com/p/new-anti-a...
onlinelibrary.wiley.com/doi/10.1111/...
Extends what I previously summarized from immune system clocks
erictopol.substack.com/p/new-anti-a...
October 9, 2025 at 10:45 PM
Hormone replacement therapy helps restore immune function in menopausal women, reducing inflammaging and preserving monocyte function. open-access
onlinelibrary.wiley.com/doi/10.1111/...
Extends what I previously summarized from immune system clocks
erictopol.substack.com/p/new-anti-a...
onlinelibrary.wiley.com/doi/10.1111/...
Extends what I previously summarized from immune system clocks
erictopol.substack.com/p/new-anti-a...
New paper alert #immunosky 🚨
What happens to our immune systems as we get older? What happens after the menopause? Turns out monocytes are actually quite important in their own right!
Check out our paper in Aging Cell now:
onlinelibrary.wiley.com/doi/10.1111/...
What happens to our immune systems as we get older? What happens after the menopause? Turns out monocytes are actually quite important in their own right!
Check out our paper in Aging Cell now:
onlinelibrary.wiley.com/doi/10.1111/...
Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy
Post-menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre-menopausal (< 40 years) females. Hormone Replace...
onlinelibrary.wiley.com
October 9, 2025 at 2:36 PM
New paper alert #immunosky 🚨
What happens to our immune systems as we get older? What happens after the menopause? Turns out monocytes are actually quite important in their own right!
Check out our paper in Aging Cell now:
onlinelibrary.wiley.com/doi/10.1111/...
What happens to our immune systems as we get older? What happens after the menopause? Turns out monocytes are actually quite important in their own right!
Check out our paper in Aging Cell now:
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Roel De Maeyer
If you have wondered how age, sex and even the menopause influences monocyte phenotype and function. Then our new preprint is for you www.biorxiv.org/content/10.1...
Age-associated inflammatory monocytes are increased in menopausal females and reversed by Hormone Replacement Therapy
Biological sex is a crucial, but poorly understood variable in age-related susceptibility to infections and chronic inflammation, inflammageing. Monocytes are important immune cells responsible for in...
www.biorxiv.org
April 2, 2025 at 7:01 AM
If you have wondered how age, sex and even the menopause influences monocyte phenotype and function. Then our new preprint is for you www.biorxiv.org/content/10.1...
First Bluesky post, and it's a good one!
Check out a brand new review in @naturerevdrugdisc.bsky.social on targeting tissue immune interactions to improve age-related immunity:
www.nature.com/articles/s41...
Check out a brand new review in @naturerevdrugdisc.bsky.social on targeting tissue immune interactions to improve age-related immunity:
www.nature.com/articles/s41...
Enhancing immunity during ageing by targeting interactions within the tissue environment - Nature Reviews Drug Discovery
Immune dysfunction increases with age owing to cellular senescence and low-grade inflammation, processes that drive each other during ageing. This Review discusses the potential of therapeutic approac...
www.nature.com
January 31, 2025 at 10:54 AM
First Bluesky post, and it's a good one!
Check out a brand new review in @naturerevdrugdisc.bsky.social on targeting tissue immune interactions to improve age-related immunity:
www.nature.com/articles/s41...
Check out a brand new review in @naturerevdrugdisc.bsky.social on targeting tissue immune interactions to improve age-related immunity:
www.nature.com/articles/s41...