Madhvi Menon
@madhvimenon.bsky.social
Immunologist at the University of Manchester | UKRI Future Leaders Fellow | Studying B cells in airway inflammation and autoimmunity | She/her
Reposted by Madhvi Menon
so excited to share our article in @nature.com Immunology on the many challenges of climate change has for our immune function, infection susceptibility and disease and the need for new ways to research this. Will do a thread later! 🧪 @lydiabeckeriii.bsky.social @exposomeimmunology.bsky.social
The role of ecoimmunology in tackling the emerging threats of climate change and the exposome
Nature Immunology - Climate change creates a multitude of challenges over the human life-course, influencing our exposomes and shaping immune function — requiring researchers to consider...
urldefense.com
November 14, 2025 at 11:17 AM
so excited to share our article in @nature.com Immunology on the many challenges of climate change has for our immune function, infection susceptibility and disease and the need for new ways to research this. Will do a thread later! 🧪 @lydiabeckeriii.bsky.social @exposomeimmunology.bsky.social
Big experiment day in the Menon lab 🧪🧫🔬
November 12, 2025 at 11:40 AM
Big experiment day in the Menon lab 🧪🧫🔬
Reposted by Madhvi Menon
So pleased to share the peer reviewed first study from our @cruk-ci.bsky.social @mcrcnews.bsky.social Radnet collab led by @nabinapun.bsky.social and Dr Cytlak with Prof Travis and Prof Illidge @lydiabeckeriii.bsky.social @mcrcellmatrix.bsky.social www.mucosalimmunology.org/article/S193...
CCR2-driven monocyte recruitment is protective against radiotherapy-induced intestinal toxicity
Radiotherapy (RT) is essential in treating abdominal and pelvic cancers but often
damages the healthy tissues, particularly the intestines, leading to radiation-induced
toxicities with limited treatme...
www.mucosalimmunology.org
October 29, 2025 at 5:23 PM
So pleased to share the peer reviewed first study from our @cruk-ci.bsky.social @mcrcnews.bsky.social Radnet collab led by @nabinapun.bsky.social and Dr Cytlak with Prof Travis and Prof Illidge @lydiabeckeriii.bsky.social @mcrcellmatrix.bsky.social www.mucosalimmunology.org/article/S193...
Reposted by Madhvi Menon
Join us at the Wellness Walkthrough: A Community Health Fair this 📆 Saturday, 1st November (🕛 12–4 PM) at 📍Castlemere Community Centre, Rochdale!
🔬 @madhvimenon.bsky.social will be there to discuss her research exploring how the immune system drives #COPD and other chronic diseases. #ImmunoSky
🔬 @madhvimenon.bsky.social will be there to discuss her research exploring how the immune system drives #COPD and other chronic diseases. #ImmunoSky
October 28, 2025 at 6:41 PM
Join us at the Wellness Walkthrough: A Community Health Fair this 📆 Saturday, 1st November (🕛 12–4 PM) at 📍Castlemere Community Centre, Rochdale!
🔬 @madhvimenon.bsky.social will be there to discuss her research exploring how the immune system drives #COPD and other chronic diseases. #ImmunoSky
🔬 @madhvimenon.bsky.social will be there to discuss her research exploring how the immune system drives #COPD and other chronic diseases. #ImmunoSky
Reposted by Madhvi Menon
📣 PhD opportunity led by @madhvimenon.bsky.social with @kathelse.bsky.social , @tracyh9494.bsky.social , and me open now:
"Sex Differences in Immune Responses to Infection: The Role of the Microbiota in Shaping Lymphocyte Dynamics"
apps due 15 November 2025 📣
www.findaphd.com/phds/project...
"Sex Differences in Immune Responses to Infection: The Role of the Microbiota in Shaping Lymphocyte Dynamics"
apps due 15 November 2025 📣
www.findaphd.com/phds/project...
(Bicentenary) Sex Differences in Immune Responses to Infection: The Role of the Microbiota in Shaping Lymphocyte Dynamics at The University of Manchester on FindAPhD.com
PhD Project - (Bicentenary) Sex Differences in Immune Responses to Infection: The Role of the Microbiota in Shaping Lymphocyte Dynamics at The University of Manchester, listed on FindAPhD.com
www.findaphd.com
October 27, 2025 at 3:24 PM
📣 PhD opportunity led by @madhvimenon.bsky.social with @kathelse.bsky.social , @tracyh9494.bsky.social , and me open now:
"Sex Differences in Immune Responses to Infection: The Role of the Microbiota in Shaping Lymphocyte Dynamics"
apps due 15 November 2025 📣
www.findaphd.com/phds/project...
"Sex Differences in Immune Responses to Infection: The Role of the Microbiota in Shaping Lymphocyte Dynamics"
apps due 15 November 2025 📣
www.findaphd.com/phds/project...
Reposted by Madhvi Menon
Friday we celebrated our new MRC Centre of Research Excellence in Exposome Immunology: a joint venture with Oxford that we call MOXIE (Manchester-Oxford Immunology of the Exposome). This challenging adventure is off to a great start. @exposomeimmunology.bsky.social
October 20, 2025 at 1:09 PM
Friday we celebrated our new MRC Centre of Research Excellence in Exposome Immunology: a joint venture with Oxford that we call MOXIE (Manchester-Oxford Immunology of the Exposome). This challenging adventure is off to a great start. @exposomeimmunology.bsky.social
Reposted by Madhvi Menon
Postdoc opportunity in the lab for a budding ILC biologist.
Informal enquiries welcome - please spread the word.
Ad closes in 4 weeks.
www.jobs.manchester.ac.uk/Job/JobDetai...
Informal enquiries welcome - please spread the word.
Ad closes in 4 weeks.
www.jobs.manchester.ac.uk/Job/JobDetai...
Research Associate - mucosal immunology and innate lymphoid cell (ILC) biology:Oxford Road
The Hepworth laboratory within the Lydia Becker Institute of Immunology and Inflammation at the University of Manchester wish to appoint a laboratory-based Research Associate to an exciting project in mucosal immunology and innate lymphoid cell (ILC) biology.
www.jobs.manchester.ac.uk
October 9, 2025 at 2:39 PM
Postdoc opportunity in the lab for a budding ILC biologist.
Informal enquiries welcome - please spread the word.
Ad closes in 4 weeks.
www.jobs.manchester.ac.uk/Job/JobDetai...
Informal enquiries welcome - please spread the word.
Ad closes in 4 weeks.
www.jobs.manchester.ac.uk/Job/JobDetai...
Reposted by Madhvi Menon
Asthma is a chronic disease characterized by acute, intermittent, recurrent episodes of airway inflammation. A decade of work developing the tools, techniques and collaborations needed to figure out how CD4+ T cells in the lungs propagate disease can be found here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Tertiary lymphoid structures support the development of allergen-specific progenitor CD4+ T cells
Tissue-resident memory CD4+ T cells (TRM) are key sentinels of the adaptive immune response that provide a rapid, robust inflammatory response upon reactivation in non-lymphoid tissues. While CD4+ TRM...
www.biorxiv.org
October 10, 2025 at 7:22 PM
Asthma is a chronic disease characterized by acute, intermittent, recurrent episodes of airway inflammation. A decade of work developing the tools, techniques and collaborations needed to figure out how CD4+ T cells in the lungs propagate disease can be found here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Madhvi Menon
I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function.
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy
Post-menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre-menopausal (< 40 years) females. Hormone Replace....
onlinelibrary.wiley.com
October 9, 2025 at 10:21 AM
I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function.
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Madhvi Menon
For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?
You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
currentprotocols.onlinelibrary.wiley.com
September 19, 2025 at 2:39 PM
For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?
You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Madhvi Menon
We now have a very exciting technician post advertised as part of our long term Wellcome Trust funded team investigating the role of the glycocalyx during CNS inflammation. Supporint the lab, developing glycan analysis and research experience www.jobs.manchester.ac.uk/Job/JobDetai...
Research Technician in the Glyco-immunology (Dyer) Lab:Oxford Road
Include: background, duties, essential skills and experience, length of contract, full or part-time. Keep to 150 words.
www.jobs.manchester.ac.uk
September 22, 2025 at 10:39 AM
We now have a very exciting technician post advertised as part of our long term Wellcome Trust funded team investigating the role of the glycocalyx during CNS inflammation. Supporint the lab, developing glycan analysis and research experience www.jobs.manchester.ac.uk/Job/JobDetai...
Reposted by Madhvi Menon
This year's Nobel Prize in Medicine honors the discovery of regulatory T cells (T-regs).
In this piece, our Director Prof Tracy Hussell @tracyh9494.bsky.social explains how the recipients discovered T-regs - transforming autoimmune disease research.
#ImmunoSky
theconversation.com/nobel-prize-...
In this piece, our Director Prof Tracy Hussell @tracyh9494.bsky.social explains how the recipients discovered T-regs - transforming autoimmune disease research.
#ImmunoSky
theconversation.com/nobel-prize-...
Nobel prize awarded for discovery of immune system’s ‘security guards’
The discovery of cells that prevent the immune system from hurting the body is paving the way for new treatments for autoimmune diseases and cancer.
theconversation.com
October 7, 2025 at 7:30 AM
This year's Nobel Prize in Medicine honors the discovery of regulatory T cells (T-regs).
In this piece, our Director Prof Tracy Hussell @tracyh9494.bsky.social explains how the recipients discovered T-regs - transforming autoimmune disease research.
#ImmunoSky
theconversation.com/nobel-prize-...
In this piece, our Director Prof Tracy Hussell @tracyh9494.bsky.social explains how the recipients discovered T-regs - transforming autoimmune disease research.
#ImmunoSky
theconversation.com/nobel-prize-...
Reposted by Madhvi Menon
Extremely happy to see our work out in #ScienceImmunology. We show allergen-induced ECM remodelling occurs independently of IL-13 or IL-17 driven inflammation. Rather chitinase-like proteins drive airway ECM accumulation & inhibition of Ym1 can remarkably reverse it. www.science.org/doi/10.1126/...
Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins
Allergic airway matrix remodeling occurs independently of IL-13 and IL-17A and is driven instead by chitinase-like proteins.
www.science.org
September 22, 2025 at 9:20 AM
Extremely happy to see our work out in #ScienceImmunology. We show allergen-induced ECM remodelling occurs independently of IL-13 or IL-17 driven inflammation. Rather chitinase-like proteins drive airway ECM accumulation & inhibition of Ym1 can remarkably reverse it. www.science.org/doi/10.1126/...
Reposted by Madhvi Menon
We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...
Research Associate in in Neuro-Immunology and Extraceullar Matrix Biology (ImmunoMatrix):Oxford Road
Our Glyco-Immunology (Dyer) lab has produced published and preliminary data demonstrating that an under-appreciated structure, the glycocalyx, on endothelial- and immune- cells regulates immune cell recruitment by:
www.jobs.manchester.ac.uk
September 12, 2025 at 3:47 PM
We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...
Reposted by Madhvi Menon
🧵How to write and manage your first research budgets
The point of funding is to convert it into quality research. A well-spent research budget should fund the idea it was raised on, plus revision experiments, plus preliminary data for the next grant. So you need to spend, while avoiding waste.
The point of funding is to convert it into quality research. A well-spent research budget should fund the idea it was raised on, plus revision experiments, plus preliminary data for the next grant. So you need to spend, while avoiding waste.
September 3, 2025 at 4:03 PM
🧵How to write and manage your first research budgets
The point of funding is to convert it into quality research. A well-spent research budget should fund the idea it was raised on, plus revision experiments, plus preliminary data for the next grant. So you need to spend, while avoiding waste.
The point of funding is to convert it into quality research. A well-spent research budget should fund the idea it was raised on, plus revision experiments, plus preliminary data for the next grant. So you need to spend, while avoiding waste.
🔔 Fantastic opportunities to join us as part of the new and exciting @exposomeimmunology.bsky.social
@lydiabeckeriii.bsky.social
Check out the details 👇
Please spread the word! #immunosky
@lydiabeckeriii.bsky.social
Check out the details 👇
Please spread the word! #immunosky
WE ARE HIRING! www.manchester.ac.uk/exposome-jobs
Vacancies inc. 3x PDRA positions, 2x data scientists and a Transition Fellowship in Air Pollution.
Join us as we embark on a 14 year journey to understand how the exposome impacts immune regulation and chronic inflammation.
#hiring #immunosky
Vacancies inc. 3x PDRA positions, 2x data scientists and a Transition Fellowship in Air Pollution.
Join us as we embark on a 14 year journey to understand how the exposome impacts immune regulation and chronic inflammation.
#hiring #immunosky
September 15, 2025 at 9:45 PM
🔔 Fantastic opportunities to join us as part of the new and exciting @exposomeimmunology.bsky.social
@lydiabeckeriii.bsky.social
Check out the details 👇
Please spread the word! #immunosky
@lydiabeckeriii.bsky.social
Check out the details 👇
Please spread the word! #immunosky
Reposted by Madhvi Menon
🎓 6x fully-funded 4-year PhD studentships 🎓
We are recruiting our first cohort of PhD students to start Oct 2026.
Students will shape their own projects within supervisory teams spanning the universities of Manchester & Oxford.
www.findaphd.com/phds/program/mrc-core-in-exposome-immunology/?p6899
We are recruiting our first cohort of PhD students to start Oct 2026.
Students will shape their own projects within supervisory teams spanning the universities of Manchester & Oxford.
www.findaphd.com/phds/program/mrc-core-in-exposome-immunology/?p6899
FindAPhD : MRC CoRE in Exposome Immunology at The University of Manchester
Apply for a PhD: MRC CoRE in Exposome Immunology at The University of Manchester
www.findaphd.com
September 9, 2025 at 11:06 AM
🎓 6x fully-funded 4-year PhD studentships 🎓
We are recruiting our first cohort of PhD students to start Oct 2026.
Students will shape their own projects within supervisory teams spanning the universities of Manchester & Oxford.
www.findaphd.com/phds/program/mrc-core-in-exposome-immunology/?p6899
We are recruiting our first cohort of PhD students to start Oct 2026.
Students will shape their own projects within supervisory teams spanning the universities of Manchester & Oxford.
www.findaphd.com/phds/program/mrc-core-in-exposome-immunology/?p6899
Reposted by Madhvi Menon
There's one week left to apply for postdoc positions in my group. Links to apply below!
#academicjobs #researchjobs #immunosky
#academicjobs #researchjobs #immunosky
Job ads for TWO postdoctoral positions available in our group are now online. Deadline August 25th.
🧪Immunologists, apply in link below.
🍄Microbiologists- please follow link in next post.
edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
🧪Immunologists, apply in link below.
🍄Microbiologists- please follow link in next post.
edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
Research Fellow - Department of Immunology and Immunotherapy - 106119 - Grade 7
The successful candidate will make extensive use of a range of in vivo models of fungal infection and will have access to the wide range of transgenic tools and in vivo immunology techniques establish...
edzz.fa.em3.oraclecloud.com
August 18, 2025 at 3:28 PM
There's one week left to apply for postdoc positions in my group. Links to apply below!
#academicjobs #researchjobs #immunosky
#academicjobs #researchjobs #immunosky
Reposted by Madhvi Menon
I am recruiting for a postdoc that wants to work on an exciting project on gut macrophages, TGFb signalling, and colon cancer! Please see the link for details - elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Postdoctoral Research Associate
We are looking for a talented and enthusiastic postdoctoral researcher to join the Shaw lab to investigate identify the regulatory function of NRROS/LRRC33 in gastrointestinal macrophage development a...
elxw.fa.em3.oraclecloud.com
August 12, 2025 at 2:56 PM
I am recruiting for a postdoc that wants to work on an exciting project on gut macrophages, TGFb signalling, and colon cancer! Please see the link for details - elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Reposted by Madhvi Menon
Dental floss as a #vaccination strategy? This study shows that floss-based vaccination can deliver protein, inactivated virus, peptide-presenting immunogenic nanoparticles, mRNA & induces #immuneresponses protecting against infectious disease in mice ➡️ www.nature.com/articles/s41... #immunity
Floss-based vaccination targets the gingival sulcus for mucosal and systemic immunization - Nature Biomedical Engineering
Floss-based vaccination exploits the leaky junctional epithelium of the gingival sulcus to deliver different types of vaccine, inducing robust mucosal and systemic immunity and providing protection ag...
www.nature.com
July 23, 2025 at 6:39 AM
Dental floss as a #vaccination strategy? This study shows that floss-based vaccination can deliver protein, inactivated virus, peptide-presenting immunogenic nanoparticles, mRNA & induces #immuneresponses protecting against infectious disease in mice ➡️ www.nature.com/articles/s41... #immunity
Reposted by Madhvi Menon
So excited to go to the IUIS and present our work on adipose tissue and systemic immunometabolism!
Meet @mcsinton.bsky.social, immunometabolism researcher & Wellcome Fellow @ Manchester. He’ll present “Fat on the frontline: fuelling immunity in chronic infection.” https://loom.ly/CwagY2g #Immunosky @lydiabeckeriii.bsky.social
July 25, 2025 at 6:45 PM
So excited to go to the IUIS and present our work on adipose tissue and systemic immunometabolism!
Reposted by Madhvi Menon
#ListerFellow Lizzy Rosser's research into juvenile idiopathic arthritis (JIA) and uveitis is driven by curiosity—and shaped by the voices of young patients and their families.
🧠 Comment how connection with patients and their families makes a difference 👇
📖 lister-institute.org.uk/the-bigger-p...
🧠 Comment how connection with patients and their families makes a difference 👇
📖 lister-institute.org.uk/the-bigger-p...
July 22, 2025 at 10:17 AM
#ListerFellow Lizzy Rosser's research into juvenile idiopathic arthritis (JIA) and uveitis is driven by curiosity—and shaped by the voices of young patients and their families.
🧠 Comment how connection with patients and their families makes a difference 👇
📖 lister-institute.org.uk/the-bigger-p...
🧠 Comment how connection with patients and their families makes a difference 👇
📖 lister-institute.org.uk/the-bigger-p...
Reposted by Madhvi Menon
🚨 A new £50M MRC Centre at @manchester.ac.uk and @ox.ac.uk will explore how pollution, microbes & other environmental exposures rewire our immune system and cause chronic inflammatory diseases.
#Exposome #ImmunoSky
sites.manchester.ac.uk/lydia-becker...
#Exposome #ImmunoSky
sites.manchester.ac.uk/lydia-becker...
New £50m MRC Centre to study how environmental exposures cause chronic inflammatory diseases
A groundbreaking £50M research centre at Manchester and Oxford will explore how environmental exposures, like pollution and microbes, rewire our immune system and drive chronic inflammatory diseases.
sites.manchester.ac.uk
July 16, 2025 at 9:41 AM
🚨 A new £50M MRC Centre at @manchester.ac.uk and @ox.ac.uk will explore how pollution, microbes & other environmental exposures rewire our immune system and cause chronic inflammatory diseases.
#Exposome #ImmunoSky
sites.manchester.ac.uk/lydia-becker...
#Exposome #ImmunoSky
sites.manchester.ac.uk/lydia-becker...
Reposted by Madhvi Menon
So excited to FINALLY be able to share exciting news from @lydiabeckeriii.bsky.social on our newly awarded MRC Centre of Research Excellence (MRC CoRE) in Exposome Immunology #ImmunoSky 🧪 🧵
July 16, 2025 at 8:35 AM
So excited to FINALLY be able to share exciting news from @lydiabeckeriii.bsky.social on our newly awarded MRC Centre of Research Excellence (MRC CoRE) in Exposome Immunology #ImmunoSky 🧪 🧵
Reposted by Madhvi Menon
Super excited to announce that MRC has funded a new Centre of Research Excellence in Exposome Immunology. Working together, Manchester and Oxford are going to tackle a major challenge of our times. For those who wonder what the Exposome is - see yesterday's posts! www.ukri.org/news/centre-...
Centre to study how exposome causes chronic inflammatory disease
A new Medical Research Council (MRC) centre will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases.
www.ukri.org
July 16, 2025 at 10:56 AM
Super excited to announce that MRC has funded a new Centre of Research Excellence in Exposome Immunology. Working together, Manchester and Oxford are going to tackle a major challenge of our times. For those who wonder what the Exposome is - see yesterday's posts! www.ukri.org/news/centre-...