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dalilatm.bsky.social
Dalila
@dalilatm.bsky.social
230 followers 310 following 180 posts
Interested in research ethics and all about #lupus #lupusnephritis | Running support group #Wales 🏴󠁧󠁢󠁷󠁬󠁳󠁿| Views my own | We need a cure for Lupus 🦋
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dalilatm.bsky.social
Dalila @dalilatm.bsky.social · Dec 11
That's a wrap #2024Wrapped! 🎉 It’s been a year of amazing guest speakers from around the globe sharing unique perspectives on lupus, plus our first F2F meeting in #Swansea 🏴󠁧󠁢󠁷󠁬󠁳󠁿🙌 Huge thanks to them & our group members. Here's to an even brighter 2025! 🌟 #lupus #Wales
Reposted by Dalila
theguardian.com
New AI tool could cut wasted efforts to transplant organs by 60%
New AI tool could cut wasted efforts to transplant organs by 60%
Machine learning model predicts whether donor is likely to die within the timeframe that liver remains viable Doctors have developed an AI tool that could reduce wasted efforts to transplant organs by 60%. Thousands of patients worldwide are waiting for a potentially life-saving donor, and more candidates are stuck on waiting lists than there are available organs. Continue reading...
www.theguardian.com
November 13, 2025 at 11:48 PM
Reposted by Dalila
psychmag.bsky.social
Childbirth – from fear and uncertainty, to confidence and calm.

Chartered Psychologist Dr Katrina Forbes-McKay joins forces with former midwife Mo Tabib to argue that ‘it’s not just knowing what to do, it’s believing you can do it’.

www.bps.org.uk/psychologist...
Childbirth – from fear and uncertainty, to confidence and calm | BPS
Chartered Psychologist Dr Katrina Forbes-McKay joins forces with former midwife Mo Tabib to argue that ‘it’s not just knowing what to do, it’s believing you can do it’.
www.bps.org.uk
November 10, 2025 at 10:04 AM
Reposted by Dalila
acr-journals.bsky.social
Editorial on this study in A&R: "The data in the paper by Tumurkhuu et al suggest that reduced TRIM21 expression in patients with lupus could contribute to cutaneous and systemic inflammation following repeated UV exposure"

doi.org/10.1002/art....
November 9, 2025 at 1:36 PM
dalilatm.bsky.social
#KidneyWeek2025 #USA 'Novel Risk Factors for Complications in Lupus Nephritis Kidney Biopsy: Use of Point-of-Care Ultrasonography (POCUS) Renal Protocol and Inflammatory Markers' #Abstract #LupusNephritis #Lupus

medjournal360.com/conference-r...
Inflammation and kidney disease severity predict bleeding risk after lupus kidney biopsy - Med Journal 360
Inflammatory activity and kidney disease severity, including high serum creatinine and class IV lupus nephritis, are associated with an increased risk of bleeding after percutaneous kidney biopsy, acc...
medjournal360.com
November 9, 2025 at 9:55 AM
dalilatm.bsky.social
That much-needed Saturday energy boost 🎶 #VivaldisWinter
November 8, 2025 at 11:57 AM
Reposted by Dalila
rheaultm.bsky.social
Samir Parikh gives an update on lupus nephritis. #KidneyWk Looking for rapid reduction of proteinuria? Voclosporin is faster, but belimumab showed similar separation from placebo, it just takes longer due to mechanism of action.
November 5, 2025 at 3:38 PM
dalilatm.bsky.social
Great to see lupus and its many complex challenges being highlighted across international media #Lupus #SLE #Awareness
November 7, 2025 at 12:58 PM
Reposted by Dalila
science.org
Short, noncoding YRNA can activate pathological variants of the innate sensor RIG-I, causing autoinflammation and #lupus nephritis in mouse models.

Learn more in #ScienceImmunology: https://scim.ag/43ewTiV
Local activation of mutant RIG-I by short noncoding Y-RNA in the kidney triggers lethal nephritis
Y-RNA activates RIG-I gain-of-function mutants in the kidney, causing lethal autoimmune diseases including lupus nephritis.
scim.ag
November 6, 2025 at 10:01 PM
Reposted by Dalila
rheumnow.bsky.social
Predicting Long-Term Proteinuria Risk in SLE

Lupus nephritis affects nearly half of SLE patients, with up to a 30% mortality rate over 10 years and 10-22% progressing to end-stage kidney disease. Early detection and diagnosis are essential.

rheumnow.com/news/decade-...
November 6, 2025 at 10:01 PM
dalilatm.bsky.social
#USA 'A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development' #Lupus #Guidelines
pubmed.ncbi.nlm.nih.gov/41182325/
A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development - PubMed
This work supported the integration of patient experiences in the clinical practice guideline development process and aligned recommendations with real-world patient experiences and priorities, thereby enhancing the clinical applicability of the ACR LN and SLE guidelines.
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 11:08 AM
dalilatm.bsky.social
Join us tomorrow! #Webinar
dalilatm.bsky.social Dalila @dalilatm.bsky.social · Jul 19
🤩 New @eular.org webinar! Join us for PAED X PARE: a unique dialogue on reproductive healthcare in childhood & juvenile onset RMDs.

🗓️ Nov 5 | 16:30–17:30 CET
📍 Teams
🔗 esor.eular.org/enrol/index....

#lupus #pedsrheum #pregnancy #RMD #rheumatology #PARE
November 4, 2025 at 2:57 PM
Reposted by Dalila
acr-journals.bsky.social
Now published: The 2025 ACR Guideline for the Treatment of Systemic Lupus Erythematosus

📄 Read the paper: acr.tw/47mkegj

ℹ️ See additional content and resources on this guideline at acr.tw/4mbHK4W

#Medsky #Rheumsky #Rheumatology
Overview of the recommended management for systemic lupus erythematosus (SLE). This schematic illustrates the approach to SLE treatment, with organ-specific therapies presented in separate boxes and stratified by disease severity. The order of the medications in each box does not indicate preference unless noted otherwise. Lupus nephritis treatment is addressed in the 2025 American College of Rheumatology Guideline for the Screening, Treatment, and Management of Lupus Nephritis. ABBREVIATIONS: ACLE, acute cutaneous lupus erythematosus; SCLE, subacute cutaneous lupus erythematosus; CCLE, chronic cutaneous lupus erythematosus; CNI, calcineurin inhibitor (cyclosporin or tacrolimus); HCQ, hydroxychloroquine; CQ, chloroquine; CCB, calcium channel blockers; IL-1 blockade, Interleukin-1 blockade; IS, immunosuppressive therapy; IV CYC, intravenous cyclophosphamide; IVIG, intravenous immunoglobulins; LCV, leukocytoclastic vasculitis; MPAA, mycophenolic acid analogs; NSAIDs, non-steroidal anti-inflammatory drugs; PDE5i, phosphodiesterase type 5 inhibitors; PLEX, plasma exchange. FOOTNOTES: ** In CLE, switch HCQ to CQ with the intention of changing back to HCQ once the rash is under control. † Azathioprine may be used when pregnancy is planned. Based on the Voting Panel members’ clinical experience, anifrolumab has a more rapid onset of benefit and a greater likelihood of response than belimumab. ⁂ MPAA may be preferable over Azathioprine § Alternative agents such as leflunomide are occasionally used for those with arthritis ‖ Evidence for severe neurologic syndromes was largely limited to IV CYC
November 3, 2025 at 4:35 PM
dalilatm.bsky.social
#Lupus Interesting! Challenges in lupus, the role of emerging technologies & the future of lupus research @sangerinstitute.bsky.social

'Five questions on lupus with Catherine Sutherland'
sangerinstitute.blog/2025/10/07/f...
Five questions on lupus with Catherine Sutherland - Wellcome Sanger Institute Blog
In recognition of UK Lupus Awareness Month, we caught up with Catherine Sutherland, Computational Senior Staff Scientist in the Human Genetics programme at the Wellcome Sanger Institute, to discuss mo...
sangerinstitute.blog
November 3, 2025 at 10:24 AM
Reposted by Dalila
acr-journals.bsky.social
Testing the ability of the Renal Activity Index for Lupus (RAIL) to discriminate LN in adults with SLE using urine samples from the TULIP-LN and TULIP-1 trials showed RAIL score could identify active LN and also differentiate treatment responders

AC&R
doi.org/10.1002/acr....

#Medsky #Nephsky
The Renal Activity Index for Lupus Identifies Active Renal Disease and Treatment Response in Adult Patients With Systemic Lupus Erythematosus and Lupus Nephritis. Graphical abstract created using BioRender
October 30, 2025 at 8:38 PM
Reposted by Dalila
rheumnow.bsky.social
SLE Conference Preview: Biologics at #ACR25

We have 4 approved lupus therapies: belimumab, voclosporin, and obinutuzumab for lupus nephritis, and belimumab and anifrolumab for non-renal SLE. What other challenges remain, and what promising treatments are on the horizon?
rheumnow.com/news/sle-con...
October 31, 2025 at 3:04 PM
Reposted by Dalila
drminidey.bsky.social
🔑 Key messages
🟣 Health literacy underpins SDM: without understanding, there is no true partnership.
🟣 Social context matters: decisions are not made isolated from patients’ daily realities.
🟣 Equity & empathy must guide SDM: tackling bias and barriers ensures everyone can participate meaningfully.
November 1, 2025 at 2:48 AM
Reposted by Dalila
royalfreecharity.org
For Lupus Awareness Month, we’re spotlighting George Robinson’s work on personalised therapies for lupus - research funded by your support. He’s studying treatments that could reduce symptoms.

Watch the full interview via the link in our bio.

#LupusAwarenessMonth #Research #NHS
October 29, 2025 at 2:09 PM
Reposted by Dalila
nkf-professionals.bsky.social
💜 Lupus Nephritis

💊 Explore challenges in diagnosis, treatment, and monitoring of lupus nephritis — plus insights on old and emerging therapies.
🧠 1.5 CME/CE credits
💻 Free for NKF Professional Members

👉 bit.ly/47t8Pu1
October 29, 2025 at 5:03 PM
Reposted by Dalila
medpagetoday.com
When treating patients with systemic lupus erythematosus (SLE) with hydroxychloroquine (HCQ), following standard dosing recommendations risks excessive toxicity or suboptimal efficacy, a researcher warned.
https://www.medpagetoday.com/meetingcoverage/acr/118202
Study: HCQ Dosing in Lupus Usually Misses the Mark
Standard recommendations lead to too much or too little in most patients
www.medpagetoday.com
October 30, 2025 at 5:27 AM
Reposted by Dalila
theguardian.com
Scans shed light on changes in brain when we zone out while tired
Scans shed light on changes in brain when we zone out while tired
Study finds lapses of attention in sleep-deprived people coincide with wave of fluid flowing out of the brain
www.theguardian.com
October 29, 2025 at 11:16 AM
Reposted by Dalila
washumedrheum.bsky.social
Dr. Akhil Sood is presenting at poster #2201 on “Adherence to Reproductive Health Guidelines in Lupus Care: Insights from Patient and Physician Surveys” so stop on by! 🎉
#ACR25 #chooserheum #rheumatology
October 28, 2025 at 4:50 PM
dalilatm.bsky.social
Always inspiring to see and follow closely the progress #research and conversations around lupus that emerge during and after #ACR Convergences 🇺🇸

📽️ Here @creakyjoints.bsky.social & Prof @ericfmorand.bsky.social at #ACR25

youtube.com/shorts/7Ent2...
Promise and Proof: Professor Eric Morand on CAR T Therapy and the Future of Lupus Treatment #ACR2025
YouTube video by CreakyJoints
youtube.com
October 28, 2025 at 11:38 AM
dalilatm.bsky.social
Interesting discussion #LupusNephritis #Lupus #SLE

www.medscape.com/viewarticle/...
Kidney Biopsy Cutoff for SLE Patients Often Misses LN Onset
The current recommended urine protein to creatinine ratio is arbitrary, and a lower bar would capture more lupus nephritis onset, researchers say. They make a case for changing the guidelines.
www.medscape.com
October 28, 2025 at 11:29 AM
Reposted by Dalila
tiffanyandlupus.bsky.social
Dr. Jillian Rose is giving a remarkably informative presentation on Sexual Health & Rheumatic conditions.

🔹 90% of women w/SLE have reduced arousal

🔹56% of women w/Sjogren’s experience vaginal dryness

🔹89% of men w/Systemic Sclerosis experience erectile dysfunction

#ACR25 #LADAorg #LupusChat
October 27, 2025 at 2:21 PM
Reposted by Dalila
rheumcat.bsky.social
Can’t get better than this start to your plenary:

“Lupus nephritis is bad.”

#ACR25
Andrea Fava speaking at the ACR plenary
October 27, 2025 at 1:31 PM