Benjamin Werner
@benjaminwerner.bsky.social
We crawl by inches.
Group Leader at Barts Cancer Institute in London. Working on somatic evolution, ecDNA, clonal haematopoiesis, gITH, clonal evolution…
https://www.bartscancer.london/staff/dr-benjamin-werner/
Contact: b.werner@qmul.ac.uk
Group Leader at Barts Cancer Institute in London. Working on somatic evolution, ecDNA, clonal haematopoiesis, gITH, clonal evolution…
https://www.bartscancer.london/staff/dr-benjamin-werner/
Contact: b.werner@qmul.ac.uk
Reposted by Benjamin Werner
Explore the origins, patterns and consequences of mutations across biological systems! #MITS26
🗓️ Conference dates: 13-15 April 2026
Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬
Check out our exciting speakers ➡️ bit.ly/4hmbnyr
#Genomics
🗓️ Conference dates: 13-15 April 2026
Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬
Check out our exciting speakers ➡️ bit.ly/4hmbnyr
#Genomics
October 27, 2025 at 8:00 AM
Explore the origins, patterns and consequences of mutations across biological systems! #MITS26
🗓️ Conference dates: 13-15 April 2026
Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬
Check out our exciting speakers ➡️ bit.ly/4hmbnyr
#Genomics
🗓️ Conference dates: 13-15 April 2026
Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬
Check out our exciting speakers ➡️ bit.ly/4hmbnyr
#Genomics
Reposted by Benjamin Werner
My institution---the Sloan Kettering Institute, the basic science arm of the Memorial Sloan Kettering Cancer Center---is hiring new faculty this cycle! Applications close Nov 15.
www.mskcc.org/research/ski...
www.mskcc.org/research/ski...
Faculty Positions
The Sloan Kettering Institute is seeking innovative scientists to join our faculty.
www.mskcc.org
October 27, 2025 at 2:45 PM
My institution---the Sloan Kettering Institute, the basic science arm of the Memorial Sloan Kettering Cancer Center---is hiring new faculty this cycle! Applications close Nov 15.
www.mskcc.org/research/ski...
www.mskcc.org/research/ski...
Haha.
L'État, c'est moi
L'État, c'est moi
BREAKING
President Trump is demanding that the DOJ pay him about $230 million in compensation for the federal investigations into him.
Any settlement will ultimately be approved by senior department officials who defended him or those in his orbit.
Full Story: nyti.ms/3WNm2sv
President Trump is demanding that the DOJ pay him about $230 million in compensation for the federal investigations into him.
Any settlement will ultimately be approved by senior department officials who defended him or those in his orbit.
Full Story: nyti.ms/3WNm2sv
October 21, 2025 at 7:29 PM
Haha.
L'État, c'est moi
L'État, c'est moi
Congratulations @mattjones.bsky.social @katerinakraft and the entire team
Delighted to share our new study in @natcellbio.nature.com showing that the unique epigenetic landscape of ecDNA can enable the oncogenic enhancer activation of transposable elements! This was a great collaboration with @katerinakraft.bsky.social and @sedonamurphy.bsky.social. tinyurl.com/mwfbu4w4
Enhancer activation from transposable elements in extrachromosomal DNA - Nature Cell Biology
Kraft, Murphy, Jones et al. identify extrachromosomal DNA (ecDNA)-interacting elements (EIEs) enriched for transposable elements within ecDNA in colorectal cancer cells. They show that EIE 14 integrat...
tinyurl.com
October 21, 2025 at 2:53 PM
Congratulations @mattjones.bsky.social @katerinakraft and the entire team
Reposted by Benjamin Werner
Looking forward, I am launching my lab in the @mitkochinstitute.bsky.social and IMES at @mit.edu, and will continue studying how the unique regulatory landscape of ecDNA enables tumor evolution. We're looking for creative scientists to push this frontier - if you're interested, get in touch!
October 21, 2025 at 2:43 PM
Looking forward, I am launching my lab in the @mitkochinstitute.bsky.social and IMES at @mit.edu, and will continue studying how the unique regulatory landscape of ecDNA enables tumor evolution. We're looking for creative scientists to push this frontier - if you're interested, get in touch!
Reposted by Benjamin Werner
man who tried to slash social security spending promises communism is coming if you just ignore the enormous job losses this year due to the technology he's developing for private profit
October 21, 2025 at 3:49 AM
man who tried to slash social security spending promises communism is coming if you just ignore the enormous job losses this year due to the technology he's developing for private profit
Yes, a citizen approach to brain surgery!
Dont trust the experts, do your own research.
Also, don’t use any electronics, this quantum mechanics hoax just tries to move you to the radical left.
Can someone give him a lab practicum please. Maybe he understands then?
Dont trust the experts, do your own research.
Also, don’t use any electronics, this quantum mechanics hoax just tries to move you to the radical left.
Can someone give him a lab practicum please. Maybe he understands then?
This makes so much sense. Never call a plumber of electrician to fix things at your house: just do your own research
RFK Jr: We need to stop trusting the experts... Trusting the experts is not a feature of science or democracy, it's a feature of religion and totalitarianism.
October 16, 2025 at 12:08 PM
Yes, a citizen approach to brain surgery!
Dont trust the experts, do your own research.
Also, don’t use any electronics, this quantum mechanics hoax just tries to move you to the radical left.
Can someone give him a lab practicum please. Maybe he understands then?
Dont trust the experts, do your own research.
Also, don’t use any electronics, this quantum mechanics hoax just tries to move you to the radical left.
Can someone give him a lab practicum please. Maybe he understands then?
Reposted by Benjamin Werner
We are hiring a postdoc to profile the evolvability of tumors in longitudinal samples from three clinical trials as part of the ARPA-H ADAPT program. This is essentially an evolutionary bioinformatics position. If you are interested, please apply here ASAP apply.interfolio.com/172521
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 14, 2025 at 9:52 PM
We are hiring a postdoc to profile the evolvability of tumors in longitudinal samples from three clinical trials as part of the ARPA-H ADAPT program. This is essentially an evolutionary bioinformatics position. If you are interested, please apply here ASAP apply.interfolio.com/172521
Reposted by Benjamin Werner
📢Exciting news! Cancer Discovery @aacrjournals.bsky.social is issuing another call for commentaries ahead of #AACR26! The meeting's theme is "Precision, Partnership, Purpose: Advancing Cancer Science to Save Lives Globally" - we want to hear YOUR ideas on how to achieve this goal. (1/2)
October 10, 2025 at 4:07 PM
📢Exciting news! Cancer Discovery @aacrjournals.bsky.social is issuing another call for commentaries ahead of #AACR26! The meeting's theme is "Precision, Partnership, Purpose: Advancing Cancer Science to Save Lives Globally" - we want to hear YOUR ideas on how to achieve this goal. (1/2)
Reposted by Benjamin Werner
Professorship in plant genetics.
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
www.berufungen.uni-kiel.de
October 12, 2025 at 9:01 AM
Professorship in plant genetics.
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
The continued move to open science and data and code availability is great.
In cancer evolution, most publications now make data and code available, helping to speed up subsequent discoveries enourmesly.
In cancer evolution, most publications now make data and code available, helping to speed up subsequent discoveries enourmesly.
October 11, 2025 at 7:42 AM
The continued move to open science and data and code availability is great.
In cancer evolution, most publications now make data and code available, helping to speed up subsequent discoveries enourmesly.
In cancer evolution, most publications now make data and code available, helping to speed up subsequent discoveries enourmesly.
If Trump gets the Peace Noble today, he should aim for Literature next.
He clearly has all the best words.
He clearly has all the best words.
October 10, 2025 at 8:48 AM
If Trump gets the Peace Noble today, he should aim for Literature next.
He clearly has all the best words.
He clearly has all the best words.
Reposted by Benjamin Werner
Our latest work is out in Nature today. In this paper, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people www.nature.com/articles/s41...
Somatic mutation and selection at population scale - Nature
A new version of nanorate DNA sequencing, with an error rate lower than five errors per billion base pairs and compatible with whole-exome and targeted capture, enables epidemiological-scale studies of somatic mutation and selection and the generation of high-resolution selection maps across coding and non-coding sites for many genes.
www.nature.com
October 8, 2025 at 4:31 PM
Our latest work is out in Nature today. In this paper, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people www.nature.com/articles/s41...
Reposted by Benjamin Werner
The October issue of Cancer Discovery @aacrjournals.bsky.social is now online! The cover features two papers on the role of #ecDNA heterogeneity in tumor evolution and adaptation to therapy - you can find these papers and much more here: aacrjournals.org/cancerdiscov...
October 6, 2025 at 6:38 PM
The October issue of Cancer Discovery @aacrjournals.bsky.social is now online! The cover features two papers on the role of #ecDNA heterogeneity in tumor evolution and adaptation to therapy - you can find these papers and much more here: aacrjournals.org/cancerdiscov...
In the hope the academic system has and continues to improve since.
For every Nobel that goes to a criminally under-recognized woman scientist (Brunkow, Karikó), or fails to go (Candy Lee), a week of mourning and reform for an academic system wherein you can do Nobel-prize-worthy-work and still end up without a conceivable path to being a professor.
BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance"
Stay tuned for more.
#NobelPrize
Stay tuned for more.
#NobelPrize
October 6, 2025 at 10:53 AM
In the hope the academic system has and continues to improve since.
Very happy ecDNA has made the cover at @aacrjournals.bsky.social, highlighting two articles in the current issue, one on MYC(N) amplification in Neuroblastoma and one on the spatial heterogeneity of ecDNA amplified oncogenes in GBM.
aacrjournals.org/cancerdiscov...
aacrjournals.org/cancerdiscov...
Volume 15 Issue 10 | Cancer Discovery | American Association for Cancer Research
aacrjournals.org
October 6, 2025 at 9:54 AM
Very happy ecDNA has made the cover at @aacrjournals.bsky.social, highlighting two articles in the current issue, one on MYC(N) amplification in Neuroblastoma and one on the spatial heterogeneity of ecDNA amplified oncogenes in GBM.
aacrjournals.org/cancerdiscov...
aacrjournals.org/cancerdiscov...
Reposted by Benjamin Werner
BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance"
Stay tuned for more.
#NobelPrize
Stay tuned for more.
#NobelPrize
October 6, 2025 at 9:34 AM
BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance"
Stay tuned for more.
#NobelPrize
Stay tuned for more.
#NobelPrize
Reposted by Benjamin Werner
Do you like theoretical biology, mathematical&conceptual modelling and want to apply yourself to cutting-edge research at all levels of biology, from molecules to ecosystems?
Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
September 29, 2025 at 7:03 AM
Do you like theoretical biology, mathematical&conceptual modelling and want to apply yourself to cutting-edge research at all levels of biology, from molecules to ecosystems?
Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Benjamin Werner
Both in the near- and long-term:
"Medicine and science will, if funded, find answers for autism, heart disease, cancer, birth defects, mental illness, and diabetes. Presidents, lawyers, and bureaucratic toadies will not."
"Medicine and science will, if funded, find answers for autism, heart disease, cancer, birth defects, mental illness, and diabetes. Presidents, lawyers, and bureaucratic toadies will not."
September 24, 2025 at 12:50 AM
Both in the near- and long-term:
"Medicine and science will, if funded, find answers for autism, heart disease, cancer, birth defects, mental illness, and diabetes. Presidents, lawyers, and bureaucratic toadies will not."
"Medicine and science will, if funded, find answers for autism, heart disease, cancer, birth defects, mental illness, and diabetes. Presidents, lawyers, and bureaucratic toadies will not."
Reposted by Benjamin Werner
Excited to announce that registration for the 13th
@mathonco.bsky.social workshop on Treatment Revolution is now open. Held onsite @moffittnews.bsky.social Nov 2-Nov 7 #MoffittIMO more details: imo13.eventbrite.com. Deluxe travel awards are available on a competitive basis, apply by 10/03!
@mathonco.bsky.social workshop on Treatment Revolution is now open. Held onsite @moffittnews.bsky.social Nov 2-Nov 7 #MoffittIMO more details: imo13.eventbrite.com. Deluxe travel awards are available on a competitive basis, apply by 10/03!
September 24, 2025 at 3:32 AM
Excited to announce that registration for the 13th
@mathonco.bsky.social workshop on Treatment Revolution is now open. Held onsite @moffittnews.bsky.social Nov 2-Nov 7 #MoffittIMO more details: imo13.eventbrite.com. Deluxe travel awards are available on a competitive basis, apply by 10/03!
@mathonco.bsky.social workshop on Treatment Revolution is now open. Held onsite @moffittnews.bsky.social Nov 2-Nov 7 #MoffittIMO more details: imo13.eventbrite.com. Deluxe travel awards are available on a competitive basis, apply by 10/03!
Reposted by Benjamin Werner
If you are interested in learning more about what an IMO Workshop is like check out our dedicated website: imoworkshop.org. Note the workshop this year runs directly after our #MathOnco25 meeting: mathematical-oncology.org/mathonco25.
#MoffittIMO Workshop
#MoffittIMO Workshop
imoworkshop.org
September 24, 2025 at 3:34 AM
If you are interested in learning more about what an IMO Workshop is like check out our dedicated website: imoworkshop.org. Note the workshop this year runs directly after our #MathOnco25 meeting: mathematical-oncology.org/mathonco25.
But who reviews the reviewers?
September 22, 2025 at 4:47 PM
But who reviews the reviewers?
Read Hannah Arendt.
It’s all there, it’s all known and yet we fall for the same cheap demagogy time and again.
What does this say about humankind?
It’s all there, it’s all known and yet we fall for the same cheap demagogy time and again.
What does this say about humankind?
September 22, 2025 at 9:07 AM
Read Hannah Arendt.
It’s all there, it’s all known and yet we fall for the same cheap demagogy time and again.
What does this say about humankind?
It’s all there, it’s all known and yet we fall for the same cheap demagogy time and again.
What does this say about humankind?
Force always attracts man of low morality.
A.E.
A.E.
September 22, 2025 at 8:21 AM
Force always attracts man of low morality.
A.E.
A.E.