Adam Pickrum
@apickrum.bsky.social
Postdoc at St. Jude with the Torres lab. Staphylococcal infection biology. Continuously pondering why bacteria win all the time.
Reposted by Adam Pickrum
🫴 Fantastic work: DNA recognition-mimicry switch governs induction in arbitrium phages:
www.sciencedirect.com/science/arti...
@spp2330.bsky.social #subtiwiki @cp-cellhostmicrobe.bsky.social
www.sciencedirect.com/science/arti...
@spp2330.bsky.social #subtiwiki @cp-cellhostmicrobe.bsky.social
A DNA recognition-mimicry switch governs induction in arbitrium phages
Temperate phages integrate multiple information sources to regulate lysis-lysogeny transitions. SPbeta-like phages use arbitrium signaling and DNA dam…
www.sciencedirect.com
January 31, 2026 at 10:24 PM
🫴 Fantastic work: DNA recognition-mimicry switch governs induction in arbitrium phages:
www.sciencedirect.com/science/arti...
@spp2330.bsky.social #subtiwiki @cp-cellhostmicrobe.bsky.social
www.sciencedirect.com/science/arti...
@spp2330.bsky.social #subtiwiki @cp-cellhostmicrobe.bsky.social
Reposted by Adam Pickrum
A prophage-encoded abortive infection protein preserves host and prophage spread www.nature.com/articles/s41...
A prophage-encoded abortive infection protein preserves host and prophage spread - Nature
A Gifsy-1 prophage–encoded higher eukaryotes and prokaryotes nucleotide-binding protein, HepS, senses Siphoviridae infection, activates abortive defence by cleaving host transfer RNAs, blocks rival ph...
www.nature.com
January 28, 2026 at 11:01 PM
Reposted by Adam Pickrum
Excited to announce the upcoming 2026 Microbial Toxins and Pathogenicity GRC and GRS meeting taking place July 12 - 17, 2026 at Waterville Valley in New Hampshire. This meeting will be chaired by yours truly and co-chaired by
@sunnyshinlab.bsky.social www.grc.org/microbial-to...
@sunnyshinlab.bsky.social www.grc.org/microbial-to...
2026 Microbial Toxins and Pathogenicity Conference GRC
The 2026 Gordon Research Conference on Microbial Toxins and Pathogenicity will be held in Waterville Valley, New Hampshire. Apply today to reserve your spot.
www.grc.org
January 24, 2026 at 1:57 PM
Excited to announce the upcoming 2026 Microbial Toxins and Pathogenicity GRC and GRS meeting taking place July 12 - 17, 2026 at Waterville Valley in New Hampshire. This meeting will be chaired by yours truly and co-chaired by
@sunnyshinlab.bsky.social www.grc.org/microbial-to...
@sunnyshinlab.bsky.social www.grc.org/microbial-to...
Reposted by Adam Pickrum
I’m thrilled to share our work on phage triggers of the bacterial immune system in its final form @natmicrobiol.nature.com www.nature.com/articles/s41...
A phage protein screen identifies triggers of the bacterial innate immune system - Nature Microbiology
A library of 400 phage protein-coding genes is used to find a trove of antiphage systems, revealing systems that target tail fibre and major capsid proteins.
www.nature.com
January 18, 2026 at 10:45 PM
I’m thrilled to share our work on phage triggers of the bacterial immune system in its final form @natmicrobiol.nature.com www.nature.com/articles/s41...
Reposted by Adam Pickrum
Enterococcus fans: Check out our latest on E. faecalis EET, advancing our understanding of both the fundamental physiology of this bug and new mechanisms of its virulence. This is the product of a thrilling collaboration with friends in Singapore @gthibault.bsky.social led by @aarontan.bsky.social.
We’ve discovered how the superbug E. faecalis prevents chronic wounds from healing.
It’s not a toxin. It’s metabolism.
The bacteria use extracellular electron transport (EET) to electrochemically generate ROS, effectively "freezing" skin cells in place.
doi.org/10.1126/sciadv.aeb5297
It’s not a toxin. It’s metabolism.
The bacteria use extracellular electron transport (EET) to electrochemically generate ROS, effectively "freezing" skin cells in place.
doi.org/10.1126/sciadv.aeb5297
Enterococcus faecalis redox metabolism activates the unfolded protein response to impair wound healing
E. faecalis EET generates ROS, which induces the UPR in keratinocytes, inhibiting in vitro migration.
doi.org
January 17, 2026 at 5:57 AM
Enterococcus fans: Check out our latest on E. faecalis EET, advancing our understanding of both the fundamental physiology of this bug and new mechanisms of its virulence. This is the product of a thrilling collaboration with friends in Singapore @gthibault.bsky.social led by @aarontan.bsky.social.
Reposted by Adam Pickrum
Registration and abstract submission for Vibrio 2026 is now open!
The preliminary program, featuring an exceptional speaker lineup, is also available.
Please share! ♻️
The preliminary program, featuring an exceptional speaker lineup, is also available.
Please share! ♻️
Delighted to announce that The International Meeting on the Biology of Vibrios will be back next year!
Vibrio2026 will be held in Berlin in September 13-16. See you there Vibriologists!
event.fourwaves.com/vibrio2026/p...
Vibrio2026 will be held in Berlin in September 13-16. See you there Vibriologists!
event.fourwaves.com/vibrio2026/p...
Vibrio2026: The International Meeting on the Biology of Vibrios
Fourwaves - Vibrio2026: The International Meeting on the Biology of Vibrios
event.fourwaves.com
January 6, 2026 at 7:51 PM
Registration and abstract submission for Vibrio 2026 is now open!
The preliminary program, featuring an exceptional speaker lineup, is also available.
Please share! ♻️
The preliminary program, featuring an exceptional speaker lineup, is also available.
Please share! ♻️
Reposted by Adam Pickrum
Really happy to have this study led by @ashleyweiss.bsky.social and Jilarie Santos-Santiago published in the Journal of Bacteriology (@asm.org) over the holiday break!! Always awesome to team up with the amazing @ritatamayo.bsky.social lab! #Cdiff #enterococci
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
January 5, 2026 at 2:26 PM
Really happy to have this study led by @ashleyweiss.bsky.social and Jilarie Santos-Santiago published in the Journal of Bacteriology (@asm.org) over the holiday break!! Always awesome to team up with the amazing @ritatamayo.bsky.social lab! #Cdiff #enterococci
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Reposted by Adam Pickrum
The Peritore Lab officially opens its doors in 2026!
I am seeking an organized, motivated technician to join our team focused on host-pathogen interaction research. For details on current research, check out: www.peritorelab.com
Job listing: osu.wd1.myworkdayjobs.com/OSUCareers/j...
#MicroSky
I am seeking an organized, motivated technician to join our team focused on host-pathogen interaction research. For details on current research, check out: www.peritorelab.com
Job listing: osu.wd1.myworkdayjobs.com/OSUCareers/j...
#MicroSky
Peritore Lab | Microbial Infection & Immunity | Ohio State University Medical Center
Peritore Lab | Microbial Infection & Immunity | Ohio State University Medical Center
www.peritorelab.com
December 31, 2025 at 4:44 PM
The Peritore Lab officially opens its doors in 2026!
I am seeking an organized, motivated technician to join our team focused on host-pathogen interaction research. For details on current research, check out: www.peritorelab.com
Job listing: osu.wd1.myworkdayjobs.com/OSUCareers/j...
#MicroSky
I am seeking an organized, motivated technician to join our team focused on host-pathogen interaction research. For details on current research, check out: www.peritorelab.com
Job listing: osu.wd1.myworkdayjobs.com/OSUCareers/j...
#MicroSky
Reposted by Adam Pickrum
[1/3] Is your favorite bacterial isolate hiding a surprise lytic virus with a VERY different lifestyle? Finally I can proudly say that our paper on persistent phages is out in Nature Microbiology. rdcu.be/eWJEp. Well done @peterdoug.bsky.social
Persistent virulent phages exist across bacterial isolates
Nature Microbiology - The long-term existence of diverse virulent phages within cultures of Escherichia coli and others challenges the virulent–temperate dichotomy and points to non-canonical...
rdcu.be
December 29, 2025 at 2:00 PM
[1/3] Is your favorite bacterial isolate hiding a surprise lytic virus with a VERY different lifestyle? Finally I can proudly say that our paper on persistent phages is out in Nature Microbiology. rdcu.be/eWJEp. Well done @peterdoug.bsky.social
Reposted by Adam Pickrum
While everyone is hustling for the holidays, hopefully folks will have time to submit abstracts or register for #ASMMicrobe2026 in DC! Please repost!
Abstract portal is open for ASM Microbe 2026. New meeting format, same great science. Hope to see you in DC!
ASM Microbe | Abstracts
ASM Microbe showcases the best microbial sciences in the world and provides a one-of-a-kind forum to explore everything from basic microbiology to translation and application.
asm.org
December 22, 2025 at 2:40 PM
While everyone is hustling for the holidays, hopefully folks will have time to submit abstracts or register for #ASMMicrobe2026 in DC! Please repost!
Reposted by Adam Pickrum
December 19, 2025 at 10:31 AM
Reposted by Adam Pickrum
🚨 New review out from our lab! We’re pleased to share our latest article @cp-cellreports.bsky.social exploring the airway immunometabolic response to common bacterial and viral pathogens. Shout out to @ridhimaw.bsky.social, Eric Tang and Roy Wong.
👉 Read it here: www.cell.com/cell-reports...
👉 Read it here: www.cell.com/cell-reports...
Airway immunometabolic responses during pulmonary bacterial and viral infections
Wadhwa et al. examine how respiratory bacterial and viral pathogens exploit host metabolism
to evade immune responses and influence disease outcomes. They underscore the need
for deeper insight into i...
www.cell.com
November 23, 2025 at 2:59 AM
🚨 New review out from our lab! We’re pleased to share our latest article @cp-cellreports.bsky.social exploring the airway immunometabolic response to common bacterial and viral pathogens. Shout out to @ridhimaw.bsky.social, Eric Tang and Roy Wong.
👉 Read it here: www.cell.com/cell-reports...
👉 Read it here: www.cell.com/cell-reports...
Reposted by Adam Pickrum
Registration is now open for @keystonesymposia.bsky.social "Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection." Deadline for scholarships and abstract selected short talks is Jan 7! Join us this May for an amazing meeting! keysym.us/KSBeyondAntibiotics26 #KSBeyondAntibiotics26
Beyond Antibiotics: Emerging Strategies for Combating Bacterial Infection | Keystone Symposia
Join us at the Keystone Symposia on Beyond Antibiotics: Emerging Strategies for Combating Bacterial Infection, May 2026, in Breckenridge, with field leaders!
keysym.us
November 19, 2025 at 5:37 PM
Registration is now open for @keystonesymposia.bsky.social "Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection." Deadline for scholarships and abstract selected short talks is Jan 7! Join us this May for an amazing meeting! keysym.us/KSBeyondAntibiotics26 #KSBeyondAntibiotics26
Reposted by Adam Pickrum
Viral AlphaFold Database (VAD) is live in Science Advances
~27,000 predicted viral protein monomers & homodimers
Conserved folds across bacteria, archaea & eukaryotic viruses
New toxin–antitoxin system KreTA uncovered
Vast “functional darkness” remains uncharted
www.science.org/doi/10.1126/...
~27,000 predicted viral protein monomers & homodimers
Conserved folds across bacteria, archaea & eukaryotic viruses
New toxin–antitoxin system KreTA uncovered
Vast “functional darkness” remains uncharted
www.science.org/doi/10.1126/...
The Viral AlphaFold Database of monomers and homodimers reveals conserved protein folds in viruses of bacteria, archaea, and eukaryotes
VAD is a Viral AlphaFold Database of protein monomers and homodimers from viruses infecting hosts across the tree of life.
www.science.org
October 2, 2025 at 8:48 AM
Viral AlphaFold Database (VAD) is live in Science Advances
~27,000 predicted viral protein monomers & homodimers
Conserved folds across bacteria, archaea & eukaryotic viruses
New toxin–antitoxin system KreTA uncovered
Vast “functional darkness” remains uncharted
www.science.org/doi/10.1126/...
~27,000 predicted viral protein monomers & homodimers
Conserved folds across bacteria, archaea & eukaryotic viruses
New toxin–antitoxin system KreTA uncovered
Vast “functional darkness” remains uncharted
www.science.org/doi/10.1126/...
Reposted by Adam Pickrum
We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 7, 2025 at 4:10 PM
We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783
Reposted by Adam Pickrum
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply here apply.interfolio.com/174404
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 5, 2025 at 12:03 PM
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply here apply.interfolio.com/174404
Reposted by Adam Pickrum
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
October 4, 2025 at 6:44 PM
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
Reposted by Adam Pickrum
Thrilled to share my work from the @jkagan1.bsky.social lab!
TLDR: O-acetylation and wall teichoic acid compete for space on S. aureus peptidoglycan. This competition regulates DNA release, and thus immune receptor activation, during infection!
www.biorxiv.org/content/10.1...
#microsky #immunosky
TLDR: O-acetylation and wall teichoic acid compete for space on S. aureus peptidoglycan. This competition regulates DNA release, and thus immune receptor activation, during infection!
www.biorxiv.org/content/10.1...
#microsky #immunosky
Wall teichoic acid is required for DNA-triggered innate immune receptor activation by Staphylococcus aureus
Receptors that stimulate inflammation are commonly activated by ligands that are buried within microbial cells. The mechanisms that facilitate immunostimulatory ligand release from microbes during inf...
www.biorxiv.org
September 26, 2025 at 11:31 AM
Thrilled to share my work from the @jkagan1.bsky.social lab!
TLDR: O-acetylation and wall teichoic acid compete for space on S. aureus peptidoglycan. This competition regulates DNA release, and thus immune receptor activation, during infection!
www.biorxiv.org/content/10.1...
#microsky #immunosky
TLDR: O-acetylation and wall teichoic acid compete for space on S. aureus peptidoglycan. This competition regulates DNA release, and thus immune receptor activation, during infection!
www.biorxiv.org/content/10.1...
#microsky #immunosky
Reposted by Adam Pickrum
Dual transposon sequencing profiles the genetic interaction landscape in bacteria | Science https://www.science.org/doi/full/10.1126/science.adt7685?af=R
Dual transposon sequencing profiles the genetic interaction landscape in bacteria
Gene redundancy complicates systematic characterization of gene function as single-gene deletions may not produce discernible phenotypes. We report dual transposon sequencing (dual Tn-seq), a platform for assaying the fitness of a comprehensive double ...
www.science.org
September 25, 2025 at 11:11 PM
Dual transposon sequencing profiles the genetic interaction landscape in bacteria | Science https://www.science.org/doi/full/10.1126/science.adt7685?af=R
Reposted by Adam Pickrum
Our Department of Microbiology & Immunology at UCSF is running a faculty search this year for a new Assistant Professor! Please see the ad below for details. Searching for a great colleague, mentor, and scientist!
aprecruit.ucsf.edu/JPF05807
aprecruit.ucsf.edu/JPF05807
Microbiology and Immunology – Faculty Position (Ladder Rank) – Assistant Professor
University of California, San Francisco is hiring. Apply now!
aprecruit.ucsf.edu
September 25, 2025 at 5:51 PM
Our Department of Microbiology & Immunology at UCSF is running a faculty search this year for a new Assistant Professor! Please see the ad below for details. Searching for a great colleague, mentor, and scientist!
aprecruit.ucsf.edu/JPF05807
aprecruit.ucsf.edu/JPF05807
Reposted by Adam Pickrum
Last month I attended the #GRS and #GRC on Staphylococcal Diseases. The conference was an excellent opportunity to meet new colleagues, learn with and about the vibrant #Staphylococcal community, and get ideas on #Zinc #ZNG1 research, coming soon
September 23, 2025 at 8:18 PM
Last month I attended the #GRS and #GRC on Staphylococcal Diseases. The conference was an excellent opportunity to meet new colleagues, learn with and about the vibrant #Staphylococcal community, and get ideas on #Zinc #ZNG1 research, coming soon
Reposted by Adam Pickrum
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
Faculty Professor Associate - Full-Time | Vaughn Cooper
We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine.
1) Fundamental researc...
www.linkedin.com
September 23, 2025 at 10:31 PM
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
Reposted by Adam Pickrum
Delighted to announce that The International Meeting on the Biology of Vibrios will be back next year!
Vibrio2026 will be held in Berlin in September 13-16. See you there Vibriologists!
event.fourwaves.com/vibrio2026/p...
Vibrio2026 will be held in Berlin in September 13-16. See you there Vibriologists!
event.fourwaves.com/vibrio2026/p...
Vibrio2026: The International Meeting on the Biology of Vibrios
Fourwaves - Vibrio2026: The International Meeting on the Biology of Vibrios
event.fourwaves.com
September 18, 2025 at 6:24 PM
Delighted to announce that The International Meeting on the Biology of Vibrios will be back next year!
Vibrio2026 will be held in Berlin in September 13-16. See you there Vibriologists!
event.fourwaves.com/vibrio2026/p...
Vibrio2026 will be held in Berlin in September 13-16. See you there Vibriologists!
event.fourwaves.com/vibrio2026/p...