Delighted that our review on resistance to last-resort antibiotics in Enterococci has been published in FEMS Microbiology Reviews
academic.oup.com/femsre/advan... (accepted manuscript version)
TL;DR: the Enterococci are really good at evolving resistance to antibiotics in new and creative ways.
academic.oup.com/femsre/advan... (accepted manuscript version)
TL;DR: the Enterococci are really good at evolving resistance to antibiotics in new and creative ways.
Resistance to last-resort antibiotics in enterococci
Abstract. The genus Enterococcus comprises a diverse group of species, many of which are commensal members of the gut microbiota of humans and animals. The
academic.oup.com
November 8, 2025 at 5:41 PM
Delighted that our review on resistance to last-resort antibiotics in Enterococci has been published in FEMS Microbiology Reviews
academic.oup.com/femsre/advan... (accepted manuscript version)
TL;DR: the Enterococci are really good at evolving resistance to antibiotics in new and creative ways.
academic.oup.com/femsre/advan... (accepted manuscript version)
TL;DR: the Enterococci are really good at evolving resistance to antibiotics in new and creative ways.
Check out our latest paper in the Journal of the American Chemical Society on the discovery of a new Streptomyces coelicolor antibiotic with potent activity against MRSA and multi-drug resistant Enterococci that has been hiding in plain sight for more than 50 years.
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Discovery of Late Intermediates in Methylenomycin Biosynthesis Active against Drug-Resistant Gram-Positive Bacterial Pathogens
The methylenomycins are highly functionalized cyclopentanone antibiotics produced by Streptomyces coelicolor A3(2). A biosynthetic pathway to the methylenomycins has been proposed based on sequence an...
pubs.acs.org
October 28, 2025 at 1:44 PM
Check out our latest paper in the Journal of the American Chemical Society on the discovery of a new Streptomyces coelicolor antibiotic with potent activity against MRSA and multi-drug resistant Enterococci that has been hiding in plain sight for more than 50 years.
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Here are Jessica Davis and Bernd Neumann who won poster awards sponsored by FEMS and its journals FEMS Microbes, and Pathogens and Disease.
September 17, 2023 at 11:54 AM
Here are Jessica Davis and Bernd Neumann who won poster awards sponsored by FEMS and its journals FEMS Microbes, and Pathogens and Disease.
JOB CLAXON!
I am recruiting a post-doctoral researcher on a BBSRC-funded project (36 months) on the genetics and functional genomics of vancomycin resistance in enterococci.
Further details here: edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
Please DM or email me if you want to discuss this post.
I am recruiting a post-doctoral researcher on a BBSRC-funded project (36 months) on the genetics and functional genomics of vancomycin resistance in enterococci.
Further details here: edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
Please DM or email me if you want to discuss this post.
Research Fellow - Department of Microbes, Infections and Microbiomes - 104864 - Grade 7
This exciting BBSRC-funded project aims to mechanistically characterise the fitness costs associated with vancomycin resistance in the Gram-positive opportunistic pathogens Enterococcus faecalis and E...
edzz.fa.em3.oraclecloud.com
November 12, 2024 at 10:41 PM
JOB CLAXON!
I am recruiting a post-doctoral researcher on a BBSRC-funded project (36 months) on the genetics and functional genomics of vancomycin resistance in enterococci.
Further details here: edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
Please DM or email me if you want to discuss this post.
I am recruiting a post-doctoral researcher on a BBSRC-funded project (36 months) on the genetics and functional genomics of vancomycin resistance in enterococci.
Further details here: edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
Please DM or email me if you want to discuss this post.
Surge in England coastlines, rivers and lakes with unsafe levels of E coli and intestinal enterococci due to sewage dumping....
www.independent.co.uk/news/uk/home...
www.independent.co.uk/news/uk/home...
Shocking state of Britain’s bathing waters revealed
Surge in coastlines, rivers and lakes with unsafe levels of E coli and intestinal enterococci due to sewage spills
www.independent.co.uk
April 22, 2025 at 8:57 AM
Surge in England coastlines, rivers and lakes with unsafe levels of E coli and intestinal enterococci due to sewage dumping....
www.independent.co.uk/news/uk/home...
www.independent.co.uk/news/uk/home...
Post 3 July 2025:
🔔 The EA has updated some of their test results, with many 11+ days old. The table shows the most recent findings for E.coli and Intestinal Enterococci in cfu/100mL.
#citizenscience #brightonandhove #seaswimming #watersports #seaswim #seaswimminguk #seaswimmer #watertesting
🔔 The EA has updated some of their test results, with many 11+ days old. The table shows the most recent findings for E.coli and Intestinal Enterococci in cfu/100mL.
#citizenscience #brightonandhove #seaswimming #watersports #seaswim #seaswimminguk #seaswimmer #watertesting
July 3, 2025 at 12:54 PM
Post 3 July 2025:
🔔 The EA has updated some of their test results, with many 11+ days old. The table shows the most recent findings for E.coli and Intestinal Enterococci in cfu/100mL.
#citizenscience #brightonandhove #seaswimming #watersports #seaswim #seaswimminguk #seaswimmer #watertesting
🔔 The EA has updated some of their test results, with many 11+ days old. The table shows the most recent findings for E.coli and Intestinal Enterococci in cfu/100mL.
#citizenscience #brightonandhove #seaswimming #watersports #seaswim #seaswimminguk #seaswimmer #watertesting
#SewageScandal: “the water quality falls below the acceptable level for safe bathing, meaning it contains too large a quantity of bacteria such as intestinal enterococci and E coli. These bacteria can cause serious illness, so people are directed to avoid swimming in areas rated poor.”
England’s swimming waters five times more likely to be polluted than in EU, research finds www.theguardian.com/environment/...
Isn't it time to re nationalise water companies for their gross profiteering behavior?
Isn't it time to re nationalise water companies for their gross profiteering behavior?
England’s swimming waters five times more likely to be polluted than in EU, research finds
Experts warn country is in danger of becoming ‘dirty man of Europe’ as it falls to bottom of bathing water leaderboard
www.theguardian.com
August 8, 2025 at 9:59 AM
#SewageScandal: “the water quality falls below the acceptable level for safe bathing, meaning it contains too large a quantity of bacteria such as intestinal enterococci and E coli. These bacteria can cause serious illness, so people are directed to avoid swimming in areas rated poor.”
Interesting paper
'Clinical characteristics, therapy and outcome of bloodstream infections caused by vancomycin-resistant enterococci: a multicentre clinical experience'
- Italy
- 97% (!) caused by E. faecium
- daptomycin-based regimen associated with survival
academic.oup.com/jac/advance-...
'Clinical characteristics, therapy and outcome of bloodstream infections caused by vancomycin-resistant enterococci: a multicentre clinical experience'
- Italy
- 97% (!) caused by E. faecium
- daptomycin-based regimen associated with survival
academic.oup.com/jac/advance-...
Clinical characteristics, therapy and outcome of bloodstream infections caused by vancomycin-resistant enterococci: a multicentre clinical experience
AbstractObjectives. Bloodstream infections (BSIs) due to vancomycin-resistant Enterococcus spp. (VRE) are considered a predictor of mortality among frail p
academic.oup.com
February 26, 2025 at 2:09 PM
Interesting paper
'Clinical characteristics, therapy and outcome of bloodstream infections caused by vancomycin-resistant enterococci: a multicentre clinical experience'
- Italy
- 97% (!) caused by E. faecium
- daptomycin-based regimen associated with survival
academic.oup.com/jac/advance-...
'Clinical characteristics, therapy and outcome of bloodstream infections caused by vancomycin-resistant enterococci: a multicentre clinical experience'
- Italy
- 97% (!) caused by E. faecium
- daptomycin-based regimen associated with survival
academic.oup.com/jac/advance-...
★ Just published: #Communicable
Nightmare Series part 3: How to deal w/ vancomycin-resistant enterococci
@angelahuttner.bsky.social & T Tangden discuss #VRE w/ Kim Kline (@kimingeneva.bsky.social) & Louis Rice (Brown University)
Listen: share.transistor.fm/s/772d59c4
#IDSky #MicroSky #MedSky #AMR
Nightmare Series part 3: How to deal w/ vancomycin-resistant enterococci
@angelahuttner.bsky.social & T Tangden discuss #VRE w/ Kim Kline (@kimingeneva.bsky.social) & Louis Rice (Brown University)
Listen: share.transistor.fm/s/772d59c4
#IDSky #MicroSky #MedSky #AMR
Communicable E12 - The Nightmare Series, part 3: How to deal with vancomycin-resistant enterococci | Communicable | Episode 12
share.transistor.fm
October 21, 2024 at 5:24 AM
★ Just published: #Communicable
Nightmare Series part 3: How to deal w/ vancomycin-resistant enterococci
@angelahuttner.bsky.social & T Tangden discuss #VRE w/ Kim Kline (@kimingeneva.bsky.social) & Louis Rice (Brown University)
Listen: share.transistor.fm/s/772d59c4
#IDSky #MicroSky #MedSky #AMR
Nightmare Series part 3: How to deal w/ vancomycin-resistant enterococci
@angelahuttner.bsky.social & T Tangden discuss #VRE w/ Kim Kline (@kimingeneva.bsky.social) & Louis Rice (Brown University)
Listen: share.transistor.fm/s/772d59c4
#IDSky #MicroSky #MedSky #AMR
We had two awards for short talks and they were both sponsored by Science Advances. The runner-up was Emma Mills for her talk 'Strain Replacement of Vancomycin-Resistant Enterococcus faecium over 6 years at a Large Tertiary Care Center'
September 17, 2023 at 11:59 AM
We had two awards for short talks and they were both sponsored by Science Advances. The runner-up was Emma Mills for her talk 'Strain Replacement of Vancomycin-Resistant Enterococcus faecium over 6 years at a Large Tertiary Care Center'
CEPHALOSPORIN-RESISTANT ORGANISMS
Resistant penicillin-binding proteins
1. Listeria monocytogenes
2.Methicilin-resistant Staphylococcus
3. Enterococci
No cel wall
4. Atypicals (Mycoplasma, Chlamydia)
Resistant penicillin-binding proteins
1. Listeria monocytogenes
2.Methicilin-resistant Staphylococcus
3. Enterococci
No cel wall
4. Atypicals (Mycoplasma, Chlamydia)
February 16, 2025 at 11:28 PM
CEPHALOSPORIN-RESISTANT ORGANISMS
Resistant penicillin-binding proteins
1. Listeria monocytogenes
2.Methicilin-resistant Staphylococcus
3. Enterococci
No cel wall
4. Atypicals (Mycoplasma, Chlamydia)
Resistant penicillin-binding proteins
1. Listeria monocytogenes
2.Methicilin-resistant Staphylococcus
3. Enterococci
No cel wall
4. Atypicals (Mycoplasma, Chlamydia)
Bobby Kennedy probably thinks that enterococci is good for you. He’ll eat feces on national television to prove it.
E. coli or enterococci, which indicate fecal matter contaminating water, were detected at swim spots in New York state, Massachusetts, Michigan and elsewhere, authorities said.
Fecal bacteria forces dozens of beach closures ahead of Fourth of July
E. coli or enterococci, which indicate fecal matter contaminating water, were detected at swim spots in New York state, Massachusetts, Michigan and elsewhere, authorities said.
www.washingtonpost.com
July 5, 2025 at 10:49 AM
Bobby Kennedy probably thinks that enterococci is good for you. He’ll eat feces on national television to prove it.
Fieldable isothermal nucleic acid test for rapid semi-quantitative visual readout of Enterococci in recreational waters https://www.biorxiv.org/content/10.1101/2025.04.20.649722v1
April 22, 2025 at 3:17 AM
Fieldable isothermal nucleic acid test for rapid semi-quantitative visual readout of Enterococci in recreational waters https://www.biorxiv.org/content/10.1101/2025.04.20.649722v1
#TidyTuesday (2025-05-20) | Water Quality at Sydney Beaches
Developed a Shiny app that enables users to assess Enterococci contamination risk.
App: adm2ru-darakhshan-nehal.shinyapps.io/bw-tracker/
Code: github.com/darakhshanne...
#rstats #shiny #leaflet #epidemiology #dataviz
Developed a Shiny app that enables users to assess Enterococci contamination risk.
App: adm2ru-darakhshan-nehal.shinyapps.io/bw-tracker/
Code: github.com/darakhshanne...
#rstats #shiny #leaflet #epidemiology #dataviz
May 31, 2025 at 7:41 PM
#TidyTuesday (2025-05-20) | Water Quality at Sydney Beaches
Developed a Shiny app that enables users to assess Enterococci contamination risk.
App: adm2ru-darakhshan-nehal.shinyapps.io/bw-tracker/
Code: github.com/darakhshanne...
#rstats #shiny #leaflet #epidemiology #dataviz
Developed a Shiny app that enables users to assess Enterococci contamination risk.
App: adm2ru-darakhshan-nehal.shinyapps.io/bw-tracker/
Code: github.com/darakhshanne...
#rstats #shiny #leaflet #epidemiology #dataviz
In case you missed it, check out our latest paper describing how vancomycin-resistant enterococci exploit antibiotic-mediated killing of gut commensals to grow in nutrient-enriched and metabolite-depleted intestines: doi.org/10.1038/s414... #AMR #GutMicrobiome
Vancomycin-resistant enterococci utilise antibiotic-enriched nutrients for intestinal colonisation - Nature Communications
Here, the authors show that vancomycin-resistant enterococci grow in the antibiotic-treated gut microbiome by utilising enriched nutrients in the presence of reduced concentrations of inhibitory micro...
doi.org
July 22, 2025 at 9:12 AM
In case you missed it, check out our latest paper describing how vancomycin-resistant enterococci exploit antibiotic-mediated killing of gut commensals to grow in nutrient-enriched and metabolite-depleted intestines: doi.org/10.1038/s414... #AMR #GutMicrobiome
⚡️ 🇲🇽 According to COFEPRIS, 18 beaches in Mexico are contaminated and unsafe to visit this summer. They have exceeded the permitted levels of enterococci. COFEPRIS advises the local population and government authorities to pay attention to these beaches and consider alternative vacation options.
Summer Vacations: These 18 Beaches Are Contaminated, COFEPRIS Alerts
🇲🇽 According to COFEPRIS, 18 beaches in Mexico are contaminated and unsafe to visit this summer. They have exceeded the permitted levels of enterococci. COFEPRIS advises the local population and government authorities to pay attention to these beaches and…
www.riskmap.com
July 18, 2024 at 2:13 AM
⚡️ 🇲🇽 According to COFEPRIS, 18 beaches in Mexico are contaminated and unsafe to visit this summer. They have exceeded the permitted levels of enterococci. COFEPRIS advises the local population and government authorities to pay attention to these beaches and consider alternative vacation options.
Managing an outbreak of vancomycin-resistant enterococci
A review of the current literature supporting health professionals in managing a vancomycin-resistant enterococci outbreak found six areas to consider Abstract Vancomycin-resistant enterococci are a common cause of healthcare-associated…
A review of the current literature supporting health professionals in managing a vancomycin-resistant enterococci outbreak found six areas to consider Abstract Vancomycin-resistant enterococci are a common cause of healthcare-associated…
Managing an outbreak of vancomycin-resistant enterococci
A review of the current literature supporting health professionals in managing a vancomycin-resistant enterococci outbreak found six areas to consider Abstract Vancomycin-resistant enterococci are a common cause of healthcare-associated infection. A literature review was conducted to understand the current evidence and support nurses and other health professionals tackling vancomycin-resistant enterococci outbreaks. It identified six key themes: risk factors, hand hygiene, environment cleaning, screening, antimicrobial stewardship and patient isolation.
indianews12.online
August 20, 2025 at 8:18 AM
Managing an outbreak of vancomycin-resistant enterococci
A review of the current literature supporting health professionals in managing a vancomycin-resistant enterococci outbreak found six areas to consider Abstract Vancomycin-resistant enterococci are a common cause of healthcare-associated…
A review of the current literature supporting health professionals in managing a vancomycin-resistant enterococci outbreak found six areas to consider Abstract Vancomycin-resistant enterococci are a common cause of healthcare-associated…
Thank you for the code, @wvschaik.bsky.social! Excited to join the community here after an awesome week of enterococci at #ICE6 in Porto!
September 15, 2023 at 10:19 PM
Thank you for the code, @wvschaik.bsky.social! Excited to join the community here after an awesome week of enterococci at #ICE6 in Porto!
The best poster prize was sponsored by the journal of Molecular Microbiology and was won by Navin Jeyabalan on his PhD research on Enterococcus faecium and its role in diabetic wound infections.
September 17, 2023 at 11:58 AM
The best poster prize was sponsored by the journal of Molecular Microbiology and was won by Navin Jeyabalan on his PhD research on Enterococcus faecium and its role in diabetic wound infections.
So excited to share a new paper from my lab just published in Nature Communications! We showed that vancomycin-resistant enterococci (VRE) occupied distinct intestinal niches in the antibiotic-treated intestine. doi.org/10.1038/s414... Amazing work by first author Olivia King and colleagues!
Vancomycin-resistant enterococci utilise antibiotic-enriched nutrients for intestinal colonisation - Nature Communications
Here, the authors show that vancomycin-resistant enterococci grow in the antibiotic-treated gut microbiome by utilising enriched nutrients in the presence of reduced concentrations of inhibitory micro...
doi.org
July 14, 2025 at 9:11 AM
So excited to share a new paper from my lab just published in Nature Communications! We showed that vancomycin-resistant enterococci (VRE) occupied distinct intestinal niches in the antibiotic-treated intestine. doi.org/10.1038/s414... Amazing work by first author Olivia King and colleagues!
9. Ceftobiprole is another cool cephalosporin, not approved yet in 🇺🇸. We can view it as a combination of cefepime + vancomycin. The cool thing with it - even though I have not used it - is that it will make great pimp questions. It has activity against enterococci and
November 18, 2024 at 5:36 AM
9. Ceftobiprole is another cool cephalosporin, not approved yet in 🇺🇸. We can view it as a combination of cefepime + vancomycin. The cool thing with it - even though I have not used it - is that it will make great pimp questions. It has activity against enterococci and
Preparing new manuscript.
Still can't spell enterococci correctly.
Sigh.
Still can't spell enterococci correctly.
Sigh.
June 6, 2025 at 12:12 PM
Preparing new manuscript.
Still can't spell enterococci correctly.
Sigh.
Still can't spell enterococci correctly.
Sigh.
Water quality off Miami Beach is shit—quite literally—with 10x safe levels of enterococci bacteria reported this week, largely due to leaky septic systems in rising groundwaters. If you are local consider contacting Mayor Levine-Cava to demand county sewers. 🌊 @miamirosenstiel.bsky.social
August 22, 2025 at 3:59 PM
Water quality off Miami Beach is shit—quite literally—with 10x safe levels of enterococci bacteria reported this week, largely due to leaky septic systems in rising groundwaters. If you are local consider contacting Mayor Levine-Cava to demand county sewers. 🌊 @miamirosenstiel.bsky.social
#MicrobiologyMonday: The "robustness" of enterococci is tied to biofilm formation. The ability to study the genetic underpinnings of biofilms formed by enterococci & other bacteria has grown, which improves understanding of their form & function. Learn more in #MMBR: journals.asm.org/doi/10.1128/...
January 6, 2025 at 1:17 PM
#MicrobiologyMonday: The "robustness" of enterococci is tied to biofilm formation. The ability to study the genetic underpinnings of biofilms formed by enterococci & other bacteria has grown, which improves understanding of their form & function. Learn more in #MMBR: journals.asm.org/doi/10.1128/...
Biliary cultures got into official recommendations (without strong evidence) so they're often done. They tend to show enterococci (among others) so patients then get add'l AB coverage.
Nice study showing there is no discernible added value to doing those cultures/widening coverage. #IDSky #MedSky
Nice study showing there is no discernible added value to doing those cultures/widening coverage. #IDSky #MedSky
January 29, 2025 at 5:32 AM