Alexander Hogrebe, PhD
@alexhgo.bsky.social
Data Scientist at MSAID 🪄 Phospho-proteomics and MS tech 🔬 He/him 🏳️🌈 Tooting privately on Mastodon @AlexHgO@fediscience.org 🐘
Pinned
🚨 New in @naturemethods.bsky.social
#CHIMERYS has already transformed #proteomics since 2022, powering DDA, DIA & PRM analysis in a single workflow.
Wanna know how CHIMERYS works? 👉 www.nature.com/articles/s41...
#TeamMassSpec #NatureMethods #ASMS2025 🧪🔬
1/7
#CHIMERYS has already transformed #proteomics since 2022, powering DDA, DIA & PRM analysis in a single workflow.
Wanna know how CHIMERYS works? 👉 www.nature.com/articles/s41...
#TeamMassSpec #NatureMethods #ASMS2025 🧪🔬
1/7
I'm truly excited to share MSAID's new publication in @naturemethods.bsky.social 🎉
We compare #CHIMERYS against state-of-the-art search engines for DDA/PRM/DIA, and even push into the realm of direct infusion #proteomics. Huge thanks to the other co-first authors and everyone involved #TeamMassSpec
We compare #CHIMERYS against state-of-the-art search engines for DDA/PRM/DIA, and even push into the realm of direct infusion #proteomics. Huge thanks to the other co-first authors and everyone involved #TeamMassSpec
Reposted by Alexander Hogrebe, PhD
“We can’t be shrinking away from this space,” say the scientists combating misinformation by taking strategies from the influencer playbook.
Good feature on what's involved in getting very online by @catrionaclarke.bsky.social @nature.com www.nature.com/articles/d41...
Good feature on what's involved in getting very online by @catrionaclarke.bsky.social @nature.com www.nature.com/articles/d41...
The science influencers going viral on TikTok to fight misinformation
Scientists and medical experts are countering climate denialism, vaccine scepticism and wellness pseudoscience on social media.
www.nature.com
February 18, 2026 at 8:47 AM
“We can’t be shrinking away from this space,” say the scientists combating misinformation by taking strategies from the influencer playbook.
Good feature on what's involved in getting very online by @catrionaclarke.bsky.social @nature.com www.nature.com/articles/d41...
Good feature on what's involved in getting very online by @catrionaclarke.bsky.social @nature.com www.nature.com/articles/d41...
Reposted by Alexander Hogrebe, PhD
1/ Finally wrote up “The Story of Mendeley”! Most people know the tool, few know about its rise and fall. The Mendeley story provides important clues for how to build self-sustaining AND non-extractive knowledge commons, which is why I think it deserves more attention 🧵
What happened to Science Goodreads and how do we rebuild it? A 65 million dollar question (at least) - CAIROS Blog
The story of the rise and fall of Mendeley
cairos.leaflet.pub
February 13, 2026 at 8:55 PM
1/ Finally wrote up “The Story of Mendeley”! Most people know the tool, few know about its rise and fall. The Mendeley story provides important clues for how to build self-sustaining AND non-extractive knowledge commons, which is why I think it deserves more attention 🧵
Reposted by Alexander Hogrebe, PhD
no foreign foe has ever dreamed of being able to sack and pillaging this country the way Trump admin and its congressional and scotus enablers do every day.
A leading American research lab is slated to lose its critical supercomputing facility, according to a letter released by the National Science Foundation.https://cnn.it/3MoF7zU
February 14, 2026 at 3:43 AM
no foreign foe has ever dreamed of being able to sack and pillaging this country the way Trump admin and its congressional and scotus enablers do every day.
Reposted by Alexander Hogrebe, PhD
AI agent goes nuts on open source maintainer after having its pull request denied. This is a pretty insane story. Open source development as we've been used to for the last few decades is likely over. 1/
theshamblog.com/an-ai-agent-...
theshamblog.com/an-ai-agent-...
An AI Agent Published a Hit Piece on Me
Summary: An AI agent of unknown ownership autonomously wrote and published a personalized hit piece about me after I rejected its code, attempting to damage my reputation and shame me into acceptin…
theshamblog.com
February 13, 2026 at 3:23 PM
AI agent goes nuts on open source maintainer after having its pull request denied. This is a pretty insane story. Open source development as we've been used to for the last few decades is likely over. 1/
theshamblog.com/an-ai-agent-...
theshamblog.com/an-ai-agent-...
Reposted by Alexander Hogrebe, PhD
🚨 Registration Opens 15th February!
Join us in Madrid on 16th April 2026 for the 3rd Annual Proteomics Gathering.
📍 Facultad de Farmacia, Universidad Complutense de Madrid, Spain
💶 Free event
🗓 16 April 2026
#APG2026 #YPIC #Proteomics
Join us in Madrid on 16th April 2026 for the 3rd Annual Proteomics Gathering.
📍 Facultad de Farmacia, Universidad Complutense de Madrid, Spain
💶 Free event
🗓 16 April 2026
#APG2026 #YPIC #Proteomics
February 13, 2026 at 2:35 PM
🚨 Registration Opens 15th February!
Join us in Madrid on 16th April 2026 for the 3rd Annual Proteomics Gathering.
📍 Facultad de Farmacia, Universidad Complutense de Madrid, Spain
💶 Free event
🗓 16 April 2026
#APG2026 #YPIC #Proteomics
Join us in Madrid on 16th April 2026 for the 3rd Annual Proteomics Gathering.
📍 Facultad de Farmacia, Universidad Complutense de Madrid, Spain
💶 Free event
🗓 16 April 2026
#APG2026 #YPIC #Proteomics
Reposted by Alexander Hogrebe, PhD
📢 Mark your calendars!
We’re excited to announce the EuBIC-MS 2027 Hackathon!
📍 Gimo, Sweden
📅 31 January – 5 February 2027
💡 Have a hackathon idea?
The call for topic proposals is now open on the EuBIC GitHub repository: github.com/EuBIC/EuBIC2...
We’re looking forward to seeing you there!
We’re excited to announce the EuBIC-MS 2027 Hackathon!
📍 Gimo, Sweden
📅 31 January – 5 February 2027
💡 Have a hackathon idea?
The call for topic proposals is now open on the EuBIC GitHub repository: github.com/EuBIC/EuBIC2...
We’re looking forward to seeing you there!
GitHub - EuBIC/EuBIC2027: Organizational repository for the EuBIC-MS Hackathon 2027
Organizational repository for the EuBIC-MS Hackathon 2027 - EuBIC/EuBIC2027
github.com
February 13, 2026 at 12:21 PM
📢 Mark your calendars!
We’re excited to announce the EuBIC-MS 2027 Hackathon!
📍 Gimo, Sweden
📅 31 January – 5 February 2027
💡 Have a hackathon idea?
The call for topic proposals is now open on the EuBIC GitHub repository: github.com/EuBIC/EuBIC2...
We’re looking forward to seeing you there!
We’re excited to announce the EuBIC-MS 2027 Hackathon!
📍 Gimo, Sweden
📅 31 January – 5 February 2027
💡 Have a hackathon idea?
The call for topic proposals is now open on the EuBIC GitHub repository: github.com/EuBIC/EuBIC2...
We’re looking forward to seeing you there!
Reposted by Alexander Hogrebe, PhD
New Yorkers return Pride flag to Stonewall after Trump administration removed it reut.rs/4qCvPyh
New Yorkers return Pride flag to Stonewall after Trump administration removed it
New York officials on Thursday hoisted a large rainbow Pride flag over the Stonewall National Monument that was removed by the Trump administration earlier in the week.
reut.rs
February 13, 2026 at 5:20 AM
New Yorkers return Pride flag to Stonewall after Trump administration removed it reut.rs/4qCvPyh
Reposted by Alexander Hogrebe, PhD
Das schlimmste Wort, das mir dort begegnet ist: Klima-Keulung (climate culling).
Natürlich wissen die Herrschaften ganz genau Bescheid über Planetare Grenzen. Ihre Antwort darauf ist in ähnlich abartiger Form verfasst, wie auch ihr sonstiger Umgang mit Menschen.
Natürlich wissen die Herrschaften ganz genau Bescheid über Planetare Grenzen. Ihre Antwort darauf ist in ähnlich abartiger Form verfasst, wie auch ihr sonstiger Umgang mit Menschen.
big thanks to @michaelemann.bsky.social who gave me some crucial context/commentary on the way 'climate change' is talked about in Epstein's emails www.fastcompany.com/91490280/eps...
'A good way of dealing with overpopulation': Epstein files reveal how the rich fuel climate denialism
Jeffrey Epstein and his vast network of elite figures routinely traded in myths that undermine climate progress. Experts say it's not an accident.
www.fastcompany.com
February 13, 2026 at 3:34 AM
Das schlimmste Wort, das mir dort begegnet ist: Klima-Keulung (climate culling).
Natürlich wissen die Herrschaften ganz genau Bescheid über Planetare Grenzen. Ihre Antwort darauf ist in ähnlich abartiger Form verfasst, wie auch ihr sonstiger Umgang mit Menschen.
Natürlich wissen die Herrschaften ganz genau Bescheid über Planetare Grenzen. Ihre Antwort darauf ist in ähnlich abartiger Form verfasst, wie auch ihr sonstiger Umgang mit Menschen.
Reposted by Alexander Hogrebe, PhD
„Wählerinnen und Wähler haben das Gefühl, dass Politik sich nicht darum bemüht, gute Rahmenbedingungen zu schaffen. Stattdessen wird irgendetwas erzählt, um an die Macht zu kommen – und dabei gleich miterzählt, dass alle das so machen würden.“
#Vertrauensverlust
web.de/magazine/pol...
#Vertrauensverlust
web.de/magazine/pol...
Polykrise in Deutschland? Was unsere Regierung laut Maja Göpel jetzt tun müsste
Eine stockende Wirtschaft, steigende Lebenshaltungskosten und kaum Fortschritte im Klimaschutz. Maja Göpel, Politökonomin und Transformationsforscherin, ordnet die politische und gesellschaftliche Lag...
web.de
February 12, 2026 at 3:15 AM
„Wählerinnen und Wähler haben das Gefühl, dass Politik sich nicht darum bemüht, gute Rahmenbedingungen zu schaffen. Stattdessen wird irgendetwas erzählt, um an die Macht zu kommen – und dabei gleich miterzählt, dass alle das so machen würden.“
#Vertrauensverlust
web.de/magazine/pol...
#Vertrauensverlust
web.de/magazine/pol...
Reposted by Alexander Hogrebe, PhD
I was getting my MPH in environmental health when the endangerment finding first allowed EPA to regulate greenhouse gases. The harm of climate change to health is real and disproportionately born by marginalized communities.
It’s gutting to see us go backwards.
www.nytimes.com/2026/02/09/c...
It’s gutting to see us go backwards.
www.nytimes.com/2026/02/09/c...
Trump Allies Near ‘Total Victory’ in Wiping Out U.S. Climate Regulation
www.nytimes.com
February 11, 2026 at 4:45 AM
I was getting my MPH in environmental health when the endangerment finding first allowed EPA to regulate greenhouse gases. The harm of climate change to health is real and disproportionately born by marginalized communities.
It’s gutting to see us go backwards.
www.nytimes.com/2026/02/09/c...
It’s gutting to see us go backwards.
www.nytimes.com/2026/02/09/c...
Reposted by Alexander Hogrebe, PhD
It is absolutely outrageous that Moderna’s flu vaccine was met with a “refusal-to-file” even after their approved their protocol with FDA and carried out the trial as agreed. This vaccine works better in older adults than the current flu vaccines.
apnews.com/article/mode...
apnews.com/article/mode...
Moderna says FDA refuses its application for new mRNA flu vaccine
The U.S. Food and Drug Administration is refusing to consider Moderna’s application for a new flu vaccine made with mRNA technology.
apnews.com
February 11, 2026 at 12:13 AM
It is absolutely outrageous that Moderna’s flu vaccine was met with a “refusal-to-file” even after their approved their protocol with FDA and carried out the trial as agreed. This vaccine works better in older adults than the current flu vaccines.
apnews.com/article/mode...
apnews.com/article/mode...
Reposted by Alexander Hogrebe, PhD
Newly released files from the investigation of convicted sex offender Jeffrey Epstein reveal that his ties to the scientific community were deeper than previously known
go.nature.com/4r4eUFD
go.nature.com/4r4eUFD
Epstein files reveal deeper ties to scientists than previously known
Latest batch of documents show researchers consulting the financier and sex offender on publications, visas and more.
go.nature.com
February 9, 2026 at 1:27 PM
Newly released files from the investigation of convicted sex offender Jeffrey Epstein reveal that his ties to the scientific community were deeper than previously known
go.nature.com/4r4eUFD
go.nature.com/4r4eUFD
Reposted by Alexander Hogrebe, PhD
No joke: I got angry hate mail today for writing an obituary of a Black woman scientist—because the person felt she did didn’t deserve the recognition.
Which just makes me want to share it again: www.nature.com/articles/d41...
Which just makes me want to share it again: www.nature.com/articles/d41...
Gladys Mae West obituary: mathematician who pioneered GPS technology
She made key contributions to US cold-war science despite facing huge barriers as a Black woman.
www.nature.com
February 6, 2026 at 9:09 AM
No joke: I got angry hate mail today for writing an obituary of a Black woman scientist—because the person felt she did didn’t deserve the recognition.
Which just makes me want to share it again: www.nature.com/articles/d41...
Which just makes me want to share it again: www.nature.com/articles/d41...
Reposted by Alexander Hogrebe, PhD
Kompromisse sind keine News, Konflikte dagegen schon - so jedenfalls tickt der Journalismus bisher. #
In der neuen Folge NEU DENKEN spricht Julia Reuschenbach mit Maja Göpel darüber, warum und wie wir Kompromisse wieder wertschätzen.
In der neuen Folge NEU DENKEN spricht Julia Reuschenbach mit Maja Göpel darüber, warum und wie wir Kompromisse wieder wertschätzen.
February 5, 2026 at 10:05 AM
Kompromisse sind keine News, Konflikte dagegen schon - so jedenfalls tickt der Journalismus bisher. #
In der neuen Folge NEU DENKEN spricht Julia Reuschenbach mit Maja Göpel darüber, warum und wie wir Kompromisse wieder wertschätzen.
In der neuen Folge NEU DENKEN spricht Julia Reuschenbach mit Maja Göpel darüber, warum und wie wir Kompromisse wieder wertschätzen.
Reposted by Alexander Hogrebe, PhD
REPOST (vom 11. Februar 2022)
youtu.be/S-Jo-djilvo
youtu.be/S-Jo-djilvo
"Right Time to Thiel" - James Bond Theme | ZDF Magazin Royale
YouTube video by ZDF MAGAZIN ROYALE
youtu.be
February 5, 2026 at 8:45 AM
REPOST (vom 11. Februar 2022)
youtu.be/S-Jo-djilvo
youtu.be/S-Jo-djilvo
Reposted by Alexander Hogrebe, PhD
The big tech founder whose 417-foot, $500 million superyacht needs a 256-foot, $75 million superyacht to "shadow" it -- because the bigger yacht lacks a helipad -- had to cut his paper's newsroom almost in half, for reasons
NEWS: The cuts were so severe that at least one department head asked to leave The Post rather than be included in the planning.
Peter Finn, The Post's international editor, requested that he be laid off once he learned about the scope of the cuts to his section.
www.nytimes.com/2026/02/04/b...
Peter Finn, The Post's international editor, requested that he be laid off once he learned about the scope of the cuts to his section.
www.nytimes.com/2026/02/04/b...
Washington Post Begins Sweeping Layoffs
www.nytimes.com
February 4, 2026 at 4:05 PM
The big tech founder whose 417-foot, $500 million superyacht needs a 256-foot, $75 million superyacht to "shadow" it -- because the bigger yacht lacks a helipad -- had to cut his paper's newsroom almost in half, for reasons
Reposted by Alexander Hogrebe, PhD
This is an intentional demolition of a very important check on power & lies. Selection of who got fired not random.
“This is a case study in near-instant, self-inflicted brand destruction.”
www.newyorker.com/news/annals-...
www.newyorker.com/news/annals-...
How Jeff Bezos Brought Down the Washington Post
The Amazon founder bought the paper to save it. Instead, with a mass layoff, he’s forced it into severe decline.
www.newyorker.com
February 5, 2026 at 3:01 AM
This is an intentional demolition of a very important check on power & lies. Selection of who got fired not random.
Reposted by Alexander Hogrebe, PhD
WaPo laid off one of the journalists who won a 2022 Pulitzer Prize for reporting on the January 6th attack on the Capitol.
February 4, 2026 at 6:16 PM
WaPo laid off one of the journalists who won a 2022 Pulitzer Prize for reporting on the January 6th attack on the Capitol.
Reposted by Alexander Hogrebe, PhD
Our recombinant, animal free, sustainable, artisanal 😁 Trypsin is here! High quality, high performance, drop in replacement for any existing #proteomics workflows.
Designed and produced in 🇩🇰🇪🇺
Designed and produced in 🇩🇰🇪🇺
Introducing Trypsin RMS – our third product is here.
Recombinant. Methylated. Sequencing-grade.
The robust trypsin #proteomics labs need, without the batch variability of animal-derived alternatives.
Learn more: kplbio.com/trypsin/
#TeamMassSpec #science #proteins #enzymes
Recombinant. Methylated. Sequencing-grade.
The robust trypsin #proteomics labs need, without the batch variability of animal-derived alternatives.
Learn more: kplbio.com/trypsin/
#TeamMassSpec #science #proteins #enzymes
February 2, 2026 at 8:34 AM
Our recombinant, animal free, sustainable, artisanal 😁 Trypsin is here! High quality, high performance, drop in replacement for any existing #proteomics workflows.
Designed and produced in 🇩🇰🇪🇺
Designed and produced in 🇩🇰🇪🇺
Reposted by Alexander Hogrebe, PhD
Apple, Google, Meta, Bluesky, Ring, Telegram—all these companies could offer stronger protections for our chats and our data. www.encryptitalready.org
Encrypt It Already
End-to-end encryption protects the privacy of your data.
encryptitalready.org
February 2, 2026 at 11:02 PM
Apple, Google, Meta, Bluesky, Ring, Telegram—all these companies could offer stronger protections for our chats and our data. www.encryptitalready.org
Reposted by Alexander Hogrebe, PhD
I have a 3-year postdoc position available at University of Manchester for a mass spec expert in proteomics. The person will be involved in exciting projects in single cell proteomics, drug discovery and innate immunity - on timsTOF Ultra AIP & HF & Astral Zoom.
www.jobs.ac.uk/job/DQJ093/r...
www.jobs.ac.uk/job/DQJ093/r...
Home - Trost Lab
www.trostlab.org
February 2, 2026 at 7:53 PM
I have a 3-year postdoc position available at University of Manchester for a mass spec expert in proteomics. The person will be involved in exciting projects in single cell proteomics, drug discovery and innate immunity - on timsTOF Ultra AIP & HF & Astral Zoom.
www.jobs.ac.uk/job/DQJ093/r...
www.jobs.ac.uk/job/DQJ093/r...
Reposted by Alexander Hogrebe, PhD
Manchmal kommt es einem so vor, dass Kompromisse zum Auslaufmodell erklärt werden – etwa dann, wenn das einseitige Durchsetzen von Positionen als Führungsstärke gefeiert wird.
In der neuen Folge NEU DENKEN geht es um Kompromisse und warum in einer Demokratie Einigung weder faul noch schwach ist.
In der neuen Folge NEU DENKEN geht es um Kompromisse und warum in einer Demokratie Einigung weder faul noch schwach ist.
February 3, 2026 at 8:48 AM
Manchmal kommt es einem so vor, dass Kompromisse zum Auslaufmodell erklärt werden – etwa dann, wenn das einseitige Durchsetzen von Positionen als Führungsstärke gefeiert wird.
In der neuen Folge NEU DENKEN geht es um Kompromisse und warum in einer Demokratie Einigung weder faul noch schwach ist.
In der neuen Folge NEU DENKEN geht es um Kompromisse und warum in einer Demokratie Einigung weder faul noch schwach ist.
Reposted by Alexander Hogrebe, PhD
Venn diagram of had friendly email correspondence with Jeffrey Epstein and argued that wokeness is a dire threat to civilization that must be stopped before it finishes destroying freedom.
January 31, 2026 at 9:57 PM
Venn diagram of had friendly email correspondence with Jeffrey Epstein and argued that wokeness is a dire threat to civilization that must be stopped before it finishes destroying freedom.
Reposted by Alexander Hogrebe, PhD
Mayor Gergely Karácsony of Budapest could teach a few American institutions how to deal with fascism.
Rather than roll over to a Pride ban, he led a march of hundreds of thousands in Budapest.
Now, he's being charged under their anti-Pride law.
But he won't be deterred.
Our latest story.
Rather than roll over to a Pride ban, he led a march of hundreds of thousands in Budapest.
Now, he's being charged under their anti-Pride law.
But he won't be deterred.
Our latest story.
Criminal Charges Pressed Against Budapest Mayor After Hundreds of Thousands Defy Pride Ban
“Despite threats or punishment, I will continue to fight. Freedom and love cannot be banned.”
www.erininthemorning.com
January 29, 2026 at 11:53 PM
Mayor Gergely Karácsony of Budapest could teach a few American institutions how to deal with fascism.
Rather than roll over to a Pride ban, he led a march of hundreds of thousands in Budapest.
Now, he's being charged under their anti-Pride law.
But he won't be deterred.
Our latest story.
Rather than roll over to a Pride ban, he led a march of hundreds of thousands in Budapest.
Now, he's being charged under their anti-Pride law.
But he won't be deterred.
Our latest story.
Reposted by Alexander Hogrebe, PhD
![3-panel comic. (1) [Three small arthropods on ocean floor.] ARTHROPOD 1: Now that we’re multicellular, what are your plans? I’m gonna evolve little legs and swim around with them! ARTHROPOD 2: I’m gonna evolve sharp pincers and use them to crunch stuff! ARTHROPOD 3: I’m gonna evolve glands to make string from my butt and use it to construct elaborate geometric nets hundreds of times my size to catch other animals. (2) [Silence] (3) ARTHROPOD 1: *Dude.* ARTHROPOD 2: Can you *please* just be normal about this? ARTHROPOD 3: *What??!*](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cz73r7iyiqn26upot4jtjdhk/bafkreia3p425asp237hjolbn5lly6g6hzm2eoygqjpkd5dii6zrwqnp7qi@jpeg)
January 28, 2026 at 7:57 PM