Alon Goren
@agoren.bsky.social
Assoc Prof. @UCSanDiego, Dept of Medicine. Developmental epigenomics: merging molecular biology, genomics, bioinformatics & tech-dev.
He/Him
He/Him
www.science.org/doi/10.1126/... related to frog in boiling water and #nokings
Will we habituate to the decline of democracy?
The recent attack on science in the US is not only undermining knowledge; it is also undermining democracy. In a healthy democracy, public policy is guided by evidence, and truth is the shared foundat...
www.science.org
October 18, 2025 at 4:26 PM
www.science.org/doi/10.1126/... related to frog in boiling water and #nokings
Reposted by Alon Goren
ICE Boasts Zero Murders Committed By 5-Year-Olds Since Child Detainments Began
ICE Boasts Zero Murders Committed By 5-Year-Olds Since Child Detainments Began
WASHINGTON—Touting a new crime report as evidence their ramped-up operations were improving American life, Immigration and Customs Enforcement officials announced Friday that there had been zero murde...
theonion.com
October 12, 2025 at 6:00 PM
ICE Boasts Zero Murders Committed By 5-Year-Olds Since Child Detainments Began
Reposted by Alon Goren
Strong statement today from UC's Academic Senate:
October 3, 2025 at 9:58 PM
Strong statement today from UC's Academic Senate:
Reposted by Alon Goren
IF ANY CALIFORNIA UNIVERSITY SIGNS THIS RADICAL AGREEMENT, THEY'LL LOSE BILLIONS IN STATE FUNDING — INCLUDING CAL GRANTS — INSTANTLY.
CALIFORNIA WILL NOT BANKROLL SCHOOLS THAT SELL OUT THEIR STUDENTS, PROFESSORS, RESEARCHERS, AND SURRENDER ACADEMIC FREEDOM.
CALIFORNIA WILL NOT BANKROLL SCHOOLS THAT SELL OUT THEIR STUDENTS, PROFESSORS, RESEARCHERS, AND SURRENDER ACADEMIC FREEDOM.
October 2, 2025 at 8:34 PM
IF ANY CALIFORNIA UNIVERSITY SIGNS THIS RADICAL AGREEMENT, THEY'LL LOSE BILLIONS IN STATE FUNDING — INCLUDING CAL GRANTS — INSTANTLY.
CALIFORNIA WILL NOT BANKROLL SCHOOLS THAT SELL OUT THEIR STUDENTS, PROFESSORS, RESEARCHERS, AND SURRENDER ACADEMIC FREEDOM.
CALIFORNIA WILL NOT BANKROLL SCHOOLS THAT SELL OUT THEIR STUDENTS, PROFESSORS, RESEARCHERS, AND SURRENDER ACADEMIC FREEDOM.
Reposted by Alon Goren
New week, new tool: Find our Protein Domain Designer tool to generate publication-ready protein domain diagrams here: domaindesigner.farnunglab.com
September 29, 2025 at 3:01 PM
New week, new tool: Find our Protein Domain Designer tool to generate publication-ready protein domain diagrams here: domaindesigner.farnunglab.com
Reposted by Alon Goren
ICE Argues Migrants In Camps Are Free To Die At Any Time https://theonion.com/ice-argues-migrants-in-camps-are-free-to-die-at-any-tim-1835623878/
September 28, 2025 at 2:30 PM
ICE Argues Migrants In Camps Are Free To Die At Any Time https://theonion.com/ice-argues-migrants-in-camps-are-free-to-die-at-any-tim-1835623878/
Reposted by Alon Goren
RFK Jr. Promotes Natural Immunity With Invitation To Touch His Festering Sore
RFK Jr. Promotes Natural Immunity With Invitation To Touch His Festering Sore
WASHINGTON—Establishing new federal guidelines for disease prevention as he moves to restrict public access to a number of vaccines, Health and Human Services Secretary Robert F. Kennedy Jr. launched ...
theonion.com
September 28, 2025 at 6:00 PM
RFK Jr. Promotes Natural Immunity With Invitation To Touch His Festering Sore
Reposted by Alon Goren
"Did I remove track changes?"
August 8, 2025 at 12:39 AM
"Did I remove track changes?"
Reposted by Alon Goren
CRISPR is amazing
September 21, 2025 at 12:56 PM
CRISPR is amazing
Reposted by Alon Goren
How every PhD project develops
September 28, 2025 at 11:21 AM
How every PhD project develops
I am thrilled to share a joint work with Melissa Gymrek that spans several years to study what is the impact of promoter proximal short tandem repeats (STRs) on expression by using MPRAs. I am sure you'd enjoy!
Awesome effort by @xzhangbsky.bsky.social and the team!
www.biorxiv.org/content/10.1...
Awesome effort by @xzhangbsky.bsky.social and the team!
www.biorxiv.org/content/10.1...
xzhangbsky.bsky.social
xzhangbsky.bsky.social
September 21, 2025 at 4:00 AM
I am thrilled to share a joint work with Melissa Gymrek that spans several years to study what is the impact of promoter proximal short tandem repeats (STRs) on expression by using MPRAs. I am sure you'd enjoy!
Awesome effort by @xzhangbsky.bsky.social and the team!
www.biorxiv.org/content/10.1...
Awesome effort by @xzhangbsky.bsky.social and the team!
www.biorxiv.org/content/10.1...
Reposted by Alon Goren
First Colbert, now Kimmel.
Last-minute settlements, secret side deals, multi-billion dollar mergers pending Donald Trump's approval.
Trump silencing free speech stifles our democracy. It sure looks like giant media companies are enabling his authoritarianism.
Last-minute settlements, secret side deals, multi-billion dollar mergers pending Donald Trump's approval.
Trump silencing free speech stifles our democracy. It sure looks like giant media companies are enabling his authoritarianism.
September 18, 2025 at 2:23 AM
First Colbert, now Kimmel.
Last-minute settlements, secret side deals, multi-billion dollar mergers pending Donald Trump's approval.
Trump silencing free speech stifles our democracy. It sure looks like giant media companies are enabling his authoritarianism.
Last-minute settlements, secret side deals, multi-billion dollar mergers pending Donald Trump's approval.
Trump silencing free speech stifles our democracy. It sure looks like giant media companies are enabling his authoritarianism.
Reposted by Alon Goren
WGA Statement on ABC’s Decision to Pull Jimmy Kimmel Live!
September 18, 2025 at 2:41 AM
WGA Statement on ABC’s Decision to Pull Jimmy Kimmel Live!
Reposted by Alon Goren
Doomscrolling pause to chat CRISPR libraries! Preprint describes our new, data-driven approach to combine on-target and off-target predictions much more intelligently for *selecting* guides, which we use to develop our newest Cas9 knockout library, Jacquere. Thread: www.biorxiv.org/content/10.1...
Balancing off-target and on-target considerations for optimized Cas9 CRISPR knockout library design
The continued development of high-dimensional CRISPR screen readouts, such as single-cell RNA sequencing and high-content imaging, necessitates compact libraries to enable functional interrogation at ...
www.biorxiv.org
September 7, 2025 at 5:02 PM
Doomscrolling pause to chat CRISPR libraries! Preprint describes our new, data-driven approach to combine on-target and off-target predictions much more intelligently for *selecting* guides, which we use to develop our newest Cas9 knockout library, Jacquere. Thread: www.biorxiv.org/content/10.1...
I'm excited to share the terrific work by my graduate student Yuwei Cao - the development and use of spa-ChIP-seq, a fully automated ChIP-seq protocol (1/3)
spa-ChIP-seq enables the comprehensive profiling of chromatin
Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is a well-established method for studying the genomic localization of DNA-associated proteins. Yet, while useful, most ChIP-seq protocol...
www.biorxiv.org
August 21, 2025 at 6:37 PM
I'm excited to share the terrific work by my graduate student Yuwei Cao - the development and use of spa-ChIP-seq, a fully automated ChIP-seq protocol (1/3)
Reposted by Alon Goren
Hey Australian genetics/genomics friends: the OurDNA Symposium will be in Sydney on 14 August, just before the HGSA meeting. Learn more about inclusive recruitment for genomics and get a preview of the OurDNA variant browser! events.humanitix.com/ourdna-sympo...
OurDNA Symposium 2025: Partnering for impact
The OurDNA Symposium brings stakeholders together for important conversations about building the foundation for equitable genomics in Australia.
events.humanitix.com
June 23, 2025 at 1:03 AM
Hey Australian genetics/genomics friends: the OurDNA Symposium will be in Sydney on 14 August, just before the HGSA meeting. Learn more about inclusive recruitment for genomics and get a preview of the OurDNA variant browser! events.humanitix.com/ourdna-sympo...
Reposted by Alon Goren
A Direct Hit, by @holdenthorp.bsky.social @science.org
www.science.org/doi/full/10....
"This is a moment to unite."
www.science.org/doi/full/10....
"This is a moment to unite."
February 11, 2025 at 3:18 PM
A Direct Hit, by @holdenthorp.bsky.social @science.org
www.science.org/doi/full/10....
"This is a moment to unite."
www.science.org/doi/full/10....
"This is a moment to unite."
Reposted by Alon Goren
Mitch McConnell Vows To Continue Falling Down Stairs In Face Of Fascist Takeover
theonion.com/mitch-m...
theonion.com/mitch-m...
Mitch McConnell Vows To Continue Falling Down Stairs In Face Of Fascist Takeover
WASHINGTON—Rebuking President Trump’s decision to pardon Jan. 6 rioters, Sen. Mitch McConnell (R-KY) staunchly vowed this week to continue falling down stairs in the face of an apparent fascist takeover. “I can no longer physically stand upright for a party that excuses a violent insurrection that targeted our Capitol,” the 82-year-old lawmaker said as he […]
theonion.com
February 8, 2025 at 4:00 PM
Mitch McConnell Vows To Continue Falling Down Stairs In Face Of Fascist Takeover
theonion.com/mitch-m...
theonion.com/mitch-m...
Reposted by Alon Goren
Science is absolutely key to the US's success but this government's intention to now dramatically reduce the part of the federal grants that go to the university (in addition to the researchers; the "indirects") is like removing the unseen roots of a tree and expecting it to continue to flourish.
February 8, 2025 at 4:40 AM
Science is absolutely key to the US's success but this government's intention to now dramatically reduce the part of the federal grants that go to the university (in addition to the researchers; the "indirects") is like removing the unseen roots of a tree and expecting it to continue to flourish.
Me: if you’re going to argue about it, we’ll have a shower every day.
10yo: so if I take a shower everyday that means I can be annoying and argue about it.
Me:
January 27, 2025 at 5:05 AM
Me: if you’re going to argue about it, we’ll have a shower every day.
10yo: so if I take a shower everyday that means I can be annoying and argue about it.
Me:
Reposted by Alon Goren
Please repost! We’re trying hard to sort out rumors from truth + would like to hear from anyone affected by the new federal orders + NIH pause. Patients, scientists, health equity researchers: please contact us below. We won’t share anything without your permission. www.statnews.com/2025/01/25/t...
Are you affected by the Trump administration’s pause on health communications, science meetings, and reviews?
Have you been affected by the Trump administration’s pause on communications, science meetings, and reviews? @statnews would like to hear from you.
www.statnews.com
January 26, 2025 at 5:02 PM
Please repost! We’re trying hard to sort out rumors from truth + would like to hear from anyone affected by the new federal orders + NIH pause. Patients, scientists, health equity researchers: please contact us below. We won’t share anything without your permission. www.statnews.com/2025/01/25/t...
Reposted by Alon Goren
“A state of panic” - yeah, that sounds about right. The “standard” budget cuts and restrictions all these agencies see every year are bad enough. Putting public health in the hands of Mr. Whale Goo gives me the screaming skeeves. 🧪
Researchers ‘in a state of panic’ after Robert F. Kennedy Jr. says Trump will hand him health agencies
Former presidential candidate holds extreme views on vaccines, disease research, drug regulation
www.science.org
October 31, 2024 at 5:40 PM
“A state of panic” - yeah, that sounds about right. The “standard” budget cuts and restrictions all these agencies see every year are bad enough. Putting public health in the hands of Mr. Whale Goo gives me the screaming skeeves. 🧪