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Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
@adamsorbie.bsky.social
Scottish computational biologist working in the Benakis lab at LMU - @ISD_Research - Microbiota and stroke
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Our article on equitable reuse of public sequencing data is out! Led by @alexjprobst.bsky.social, @lhug.bsky.social, Cristina Moraru, @geomicrosoares.bsky.social, @folker.bsky.social and myself -, co-authored by Anke Heyder, and developed in consultation with 167 scientists. tinyurl.com/n6yeanmk
A roadmap for equitable reuse of public microbiome data - Nature Microbiology
In this Consensus Statement, a consortium of microbiome scientists discuss current sequencing data sharing policies and propose the use of a Data Reuse Information (DRI) tag to promote equitable and collaborative data sharing.
tinyurl.com
September 26, 2025 at 8:14 PM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
I am old. I’ve been through so many waves of hustle culture. Outside of occasional crunch times, the overwork is always unnecessary, performative nonsense that provides cover for some combination of bad ideas, abusive leadership, disorganization, a total lack of strategy etc etc.
September 3, 2025 at 4:13 AM
Very happy to see some of my PhD work finally out!
Happy to share our latest paper showing that intestinal inflammation (IL10-/-) + an UPRER diva protein (ATF6) = a perfect storm for colon cancer: Susceptibility to inflammatory bowel diseases promotes invasive carcinomas in a murine model of ATF6-driven colon cancer. academic.oup.com/ecco-jcc/art...
Susceptibility to inflammatory bowel diseases promotes invasive carcinomas in a murine model of ATF6-driven colon cancer
AbstractBackground and aims. Chronic inflammation in inflammatory bowel disease (IBD) patients represents a risk factor for developing colitis-associated c
academic.oup.com
July 24, 2025 at 11:16 AM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
🥁NEW publication from our lab:
the largest meta-analysis of gut microbiome associations with CRC!

www.nature.com/articles/s41...

🧵⬇️

1/6
Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer - Nature Medicine
An analysis of 18 metagenomic datasets of individuals with colorectal cancer, adenomas and healthy controls yields improved cancer prediction accuracy based solely on gut metagenomics, as well as the ...
www.nature.com
June 3, 2025 at 10:43 AM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
The latest from the StatDivLab -- guidance for your #microbiome data analysis with a focus on the #statistics. Planning, deciding, modeling, justifying, communicating, visualizing...

"Papers Need Friends" blog post coming shortly.
February 21, 2025 at 3:03 PM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Happy to announce that MEDI, our method to quantify dietary intake through metagenomics is out now. 🧬 🧪🧫🦠 www.nature.com/articles/s42...

#metagenomics #microbiome #microbiomesky

So what is MEDI? A combination of two things:
Metagenomic estimation of dietary intake from human stool - Nature Metabolism
Diener et al. present a method that allows the estimation of dietary intake from human stool by detecting food-derived DNA in faecal metagenomes.
www.nature.com
February 18, 2025 at 11:02 AM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Congratulations to the virus and bacteria communities on the confirmation of their longtime supporter and champion Robert F. Kennedy Jr as secretary of health and human services.
February 14, 2025 at 7:52 AM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Ever wondered how gut microbes control immune responses at extra-intestinal locations?
Here #theonlylabever reports how a gut protozoan commensal shapes pulmonary immunity to exacerbate asthma and limit the dissemination of mycobacteria.
@cellpress.bsky.social ⬇️(1/x)
www.cell.com/cell/fulltex...
December 19, 2024 at 9:30 PM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Today we publish an (in my opinion) important paper in
@naturemicrobiol.bsky.social 🍾 showing that gut physiology and environment are factors explaining substantial variations in human gut #microbiome composition and #metabolism🦠
Fantastic work Procházková et al. 👏
www.nature.com/articles/s41...
Gut physiology and environment explain variations in human gut microbiome composition and metabolism - Nature Microbiology
An observational longitudinal clinical trial, incorporating a SmartPill and metabolomics, reveals the role of host factors in shaping the gut microbiome in healthy human adults.
www.nature.com
November 27, 2024 at 10:36 AM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Why we should stop looking for an NPI miracle - new post on underpowered trials and future disease threats: kucharski.substack.com/p/stop-looki...
November 15, 2024 at 7:27 AM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Your regular reminder about editorial standards at Frontiers.
February 15, 2024 at 6:09 PM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Are you a data creator/user in #metagenomics or other #omics? We’re working on standards for fair data reuse and would like your feedback. We welcome contributions by scientists from all career stages. 5-min anonymous survey here: shorturl.at/NOUW2 Please RT!
January 15, 2024 at 3:57 PM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
We're coming to the end of 2023, and I wanted to do a roundup of a few of my favorite microbiome papers of the year. So, in no particular order, here it goes:
December 26, 2023 at 5:54 PM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Post a meme made by you
December 19, 2023 at 12:01 PM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Public Service Announcement:

"A popular and incorrect view on the evolution of virulence, frequently expressed in the context of SARS-CoV-2, is that in the long run, pathogens will tend to evolve to be decreasingly virulent"

From www.nature.com/articles/s41...
The evolution of SARS-CoV-2 - Nature Reviews Microbiology
In this Review, Markov, Katzourakis and colleagues explore the evolution of SARS-CoV-2 at different scales, the phases of the COVID-19 pandemic, factors that drive the evolution of the virus, theories...
www.nature.com
December 11, 2023 at 7:22 AM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Not enough people know about bioicons.com
Open source vector graphics. Free alternatives to BioRender.
November 8, 2023 at 3:17 PM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Happy to share our latest preprint -- we built an integrated compendium of all publicly available human gut microbiome 16S data (~168,000 samples) and used it to explore patterns of microbiome variation around the world

www.biorxiv.org/content/10.1...
October 17, 2023 at 6:20 PM
Reposted by Adam Sorbie 🏴󠁧󠁢󠁳󠁣󠁴󠁿🔬
Microbiome twitter, we are looking for negative control samples from as many sources and kits as possible. If you've included blanks in your 16S or ITS amplicon seq project and the data is publicly available, drop a link in the thread!

RTs appreciated!
October 5, 2023 at 11:33 AM
Loving bluesky so far. Not soo much going on yet on my timeline but at least there’s no ads or bluetick nonsense.
September 21, 2023 at 8:00 PM