Benoit Ladoux
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bladoux.bsky.social
Benoit Ladoux
@bladoux.bsky.social

Biophysics / Cell Migration / Active matter / Mechanobiology
https://mpzpm.mpg.de/research/benoit-ladoux
https://ladoux-mege-lab.cnrs.fr

Biology 50%
Engineering 28%
Pinned
Just out! Our work on active transport in epithelial tissues. Congrats to Huiqiong Wu, Greg Arkowitz and Ranjith Chilupuri in collaboration with C. Duclut and J. Prost!
PNAS www.pnas.org/doi/10.1073/...

Reposted by Benoît Ladoux

Curious to read about the 'Physical Basis of Sarcomere Assembly'. Here are some thoughts from @friedrich-group.bsky.social and me - you might learn the difference between nematic and smectic order in biological assemblies pubs.aip.org/aip/bpr/arti...

En cette fin d’année, je veux remercier trois personnes qui ont vraiment élevé le niveau du débat par leur intelligence, leur pédagogie et leur rigueur.
Merci à:
@gabrielzucman.bsky.social
@vincent-lemire.bsky.social
@fabricearfi.bsky.social

Reposted by Benoît Ladoux

Paper alert! β-catenin forms condensates that help build cell–cell adhesions - showing its role goes beyond simply linking E-cadherin to α-cat/actin. Great collaboration with the Schuijers lab!

👉 nature.com/articles/s41...

Reposted by Benoît Ladoux

📣 New preprint from the @minclab.bsky.social

📃 A CROSS-SPECIES ANALYSIS OF CELL WALL MECHANOSENSORS
🔗 www.biorxiv.org/content/10.1...

Reposted by Benoît Ladoux

✍️ The @bladoux.bsky.social / @rmmege.bsky.social Lab published a new article

📖 @softmatter.rsc.org
📃 Radical scaling: beyond our feet and fingers
🔗 pubs.rsc.org/en/content/a...

Reposted by Benoît Ladoux

We are recruiting a tenure track professor in the broader area of molecular biology @zmbh.uni-heidelberg.de at Heidelberg University! www.nature.com/naturecareer... Please share and apply!
Tenure Track Professorship (W1 with Tenure Track to W3) in “Molecular Biology" (f/m/d) - Heidelberg job with Universität Heidelberg | 12850668
The Center for Molecular Biology of Heidelberg University (ZMBH) and the Faculty of Biosciences invite applications for a   Tenure Track Professors...
www.nature.com

Reposted by Benoît Ladoux

Reviewing process has always been painfull, but it will just become useless and impossible to publish if we start accepting this (we are not helping science...and better refusing to review if you have no time rather than using these tools without filter)

Reposted by Benoît Ladoux

Are you investigating cell tissues and interested in stress patterns? TFM + BISM reveals them! 👇

With @luanger.bsky.social and P. Marcq, we summarise the applicability across different exp. conditions regularly used in the @bladoux.bsky.social @rmmege.bsky.social lab.
Full pipeline on Lucas GitHub!

Reposted by Benoît Ladoux

Come join us in beautiful Roscoff for this Conference Jacques Monod on Developmental regulation: from molecular to ecological niches
May 18-22, 2026 Roscoff, France
Abstract deadline: January 31, 2026
Apply here: cjm.sb-roscoff.fr/en

Reposted by Benoît Ladoux

The NIH grant cuts in 2025
www.nytimes.com/interactive/...

Tissue stress measurements — our latest preprint is out: arxiv.org/abs/2512.00550
(publication coming soon!)
Fantastic work by the three musketeers — @luanger.bsky.social, @andreasschoenit.bsky.social and @fanny-wodrascka.bsky.social — in collaboration with P. Marcq!
Tissue stress measurements with Bayesian Inversion Stress Microscopy
Cells within biological tissue are constantly subjected to dynamic mechanical forces. Measuring the internal stress of tissues has proven crucial for our understanding of the role of mechanical forces...
arxiv.org

Reposted by Benoît Ladoux

Reposted by Benoît Ladoux

· #AcademicSky ·
The European Research Council is launching €7m Plus Grants for ambitious, long‑term research — open to researchers at any career stage but limited to about 30 awards; current ERC grantees and applicants are ineligible, reports @clanicholson.bsky.social.
ERC’s new €7m Plus Grants open to researchers at any career stage - Research Professional News
European Research Council president describes scheme as part attempt to lure US talent
www.researchprofessionalnews.com

Reposted by Benoît Ladoux

The Bohr effect had nothing to do with Niels but was discovered by his physiologist father Christian. Taught now as the first example of allostery in protein action, it touched on deeper questions about the nature of living organisms. My lastest column for CW
www.chemistryworld.com/opinion/the-...
The wide-ranging influence of the Bohr effect
While not a Nobel prize-winning discovery in itself, this challenge to the reductionist view of physiology has links to several other winners
www.chemistryworld.com

Reposted by Benoît Ladoux

🧪 Geometry beats chemistry: we show that self-assembly can be controlled by tuning large-scale geometric parameters rather than molecular binding energies.
PNAS: doi.org/10.1073/pnas...
Video summary: www.youtube.com/watch?v=6FS3...
#SelfAssembly #Biophysics #PhysicsOfLife

Reposted by Benoît Ladoux

📣 2nd meeting of France-BioImaging Mechanobiology Working Group

📆 March 26-27th, 2026
📍Institut Jacques Monod, Buffon amphitheater

Registration are open until December 31st 🔗 buff.ly/cVzaoId

@upcite.bsky.social @sbcf.bsky.social @gdraqv.bsky.social @cnrsbiologie.bsky.social @psl-univ.bsky.social
2nd meeting of France-BioImaging Mechanobiology Working Group
The second meeting of the FBI Mechanobiology WG will take place on the 26 and 27 of March 2026 at the Institut de Biologie Paris Seine and the Institut Jacques Monod in Paris. The programme will in…
france-bioimaging.org

Congrats! Grandement mérité!

Reposted by Benoît Ladoux

We are looking to hire a postdoc to work on the regulation of microtubule nucleation in neurons. See advert attached. Contact me by email for any extra info.

Reposted by Benoît Ladoux

#JobOffer

💼 Ingénieur de recherche H/F en biophysique de l'infection bactérienne
📆 12 Janvier 2026
📍équipe Bonazzi

Candidatez sur le portail emploi CNRS avant le 15 décembre 🔗 emploi.cnrs.fr/Offres/CDD/U...

Reposted by Benoît Ladoux

Check out our latest published manuscript: SurFlex microscopy, a new technique to measure molecular flexibility. Congrats to Aymeric, @sid592.bsky.social, @blenackmon.bsky.social, and Andres! www.pnas.org/doi/10.1073/...
SurFlex microscopy: Measuring flexibility of surface-tethered biomolecules | PNAS
The flexibility of tethered molecules, such as those bound to biological membranes, is an important property that can influence molecular height, m...
www.pnas.org

Reposted by Benoît Ladoux

𝐍𝐞𝐰 𝐩𝐫𝐞𝐩𝐫𝐢𝐧𝐭 𝐚𝐥𝐞𝐫𝐭! 🎉
“𝐗𝐈𝐒𝐓 𝐃𝐫𝐢𝐯𝐞𝐬 𝐗-𝐂𝐡𝐫𝐨𝐦𝐨𝐬𝐨𝐦𝐞 𝐈𝐧𝐚𝐜𝐭𝐢𝐯𝐚𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐒𝐚𝐟𝐞𝐠𝐮𝐚𝐫𝐝𝐬 𝐅𝐞𝐦𝐚𝐥𝐞 𝐄𝐱𝐭𝐫𝐚𝐞𝐦𝐛𝐫𝐲𝐨𝐧𝐢𝐜 𝐂𝐞𝐥𝐥𝐬 𝐢𝐧 𝐇𝐮𝐦𝐚𝐧𝐬” 𝐢𝐬 𝐧𝐨𝐰 𝐨𝐧 𝐛𝐢𝐨𝐑𝐱𝐢𝐯!
www.biorxiv.org/content/10.1...
XIST Drives X-Chromosome Inactivation and Safeguards Female Extraembryonic Cells in Humans
Dosage compensation of sex chromosomes through X-chromosome inactivation (XCI) is required for mice extra-embryonic tissue growth and embryo development. The species specificity in mechanisms and timi...
www.biorxiv.org

Reposted by Benoît Ladoux

✍️ The Pintard Lab ( @ccdlab.bsky.social ) published a new article

📖 @jcb.org
📃 Intramolecular regulation of the MT-severing enzyme Katanin prevents futile ATP hydrolysis

🔗 rupress.org/jcb/article-...

Reposted by Benoît Ladoux

Congratulations to Celia Municio-Diaz in the lab for this new publication, showing that Cell Wall mechanosensors taken from distant yeast species can still function and detect forces in the foreign cell wall of fission yeast cells!

@ijmonod.bsky.social @cnrsbiologie.bsky.social

Reposted by Benoît Ladoux

📢 PhD Thesis defense

📅 November 26th
📍Institut Jacques Monod

Tomorrow, Fanny Wodrascka ( @fanny-wodrascka.bsky.social @bladoux.bsky.social @rmmege.bsky.social ) will defend her PhD thesis "Mechanical control of epithelial cell extrusion via RhoA-dependent contractility "

➡️ buff.ly/f5VaVah

Reposted by Benoît Ladoux

There's only one week left to apply to our Integrated MSc/PhD program - apply now! mattertolife.maxplanckschools.org/application
Over many interviews, Robert F. Kennedy Jr. told Michael Scherer about how he plans to remake America’s public-health system. Can he lead the scientific establishment he’s spent much of his life crusading against?

Read more in our new cover story: theatln.tc/q9hXxlbM

Reposted by Benoît Ladoux

is there a direct crosstalk between actin and vimentin intermediate filaments? Our work shows that vimentin promotes actin assembly by stabilizing ATP-subunits at the barbed end.
Fantastic work done by @lilianpaty.bsky.social with @romet-jegou-lab.bsky.social

www.biorxiv.org/content/10.1...

Reposted by Benoît Ladoux

Very happy to share video of 1st lecture @college-de-france.fr on Biological computation 😊. I defend the necessity to access Algorithmic & Computational levels of analysis in cell & developmental biol. proposed by David Marr in neuroscience. Logic & Function matter 🤩.
Video: tinyurl.com/55yejk5f
Qu’est-ce que l’information biologique (suite) ? (1) - Thomas Lecuit (2025-2026)
Enseignement 2025-2026 : Qu’est-ce que l’information biologique (suite) ? Cours du 20 décembre 2025 : Introduction : approche computationelle du vivant Professeur : Thomas Lecuit Chaire Dynamiques du vivant Retrouvez les enregistrements audios et vidéos du cycle : https://www.college-de-france.fr/fr/agenda/cours/qu-est-ce-que-information-biologique Tous les enseignements du Pr Thomas Lecuit : https://www.college-de-france.fr/chaire/thomas-lecuit-dynamiques-du-vivant-chaire-statutaire https://www.youtube.com/playlist?list=PLOj9pZ2YNGZ84uMY6DhPnqpL1rq5qNAVJ Le Collège de France est une institution de recherche fondamentale dans tous les domaines de la connaissance et un lieu de diffusion du « savoir en train de se faire » ouvert à tous. Les cours, séminaires, colloques sont enregistrés puis mis à disposition du public sur le site internet du Collège de France. Découvrez toutes les ressources du Collège de France : https://www.college-de-france.fr Soutenir le Collège de France : https://www.fondation-cdf.fr/faire-un-don Suivez-nous sur : Threads : https://www.threads.net/@collegedefrance Bluesky : https://bsky.app/profile/college-de-france.fr Facebook : https://www.facebook.com/College.de.France Instagram : https://www.instagram.com/collegedefrance LinkedIn : https://fr.linkedin.com/company/coll%C3%A8gedefrance
tinyurl.com

Reposted by Benoît Ladoux

📢 Institut Jacques Monod Seminar

📅 November 25th
📍 Institut Jacques Monod

Tomorrow, Magali Suzanne will present the Institut Jacques Monod seminar « Spatio-temporal control of nuclear Mechanotransduction during Epithelial-to-Mesenchymal transition »

➡️ buff.ly/ajrwbxo