I'm looking at some Arabidopsis scRNA-seq data and found that the MEP pathway is expressed in the mesophyll & bundle sheath. In various species that produce monoterpene indole alkaloids (e.g., Catharanthus), the MEP pathway is restricted to a rare cell type. Not sure what this means. #PlantScience
January 14, 2026 at 1:11 AM
I'm looking at some Arabidopsis scRNA-seq data and found that the MEP pathway is expressed in the mesophyll & bundle sheath. In various species that produce monoterpene indole alkaloids (e.g., Catharanthus), the MEP pathway is restricted to a rare cell type. Not sure what this means. #PlantScience
Protein–Protein Interactions Modulate a Key Branch Point in Monoterpene Indole Alkaloid Biosynthesis | ACS Chemical Biology pubs.acs.org/doi/full/10....
Protein–Protein Interactions Modulate a Key Branch Point in Monoterpene Indole Alkaloid Biosynthesis
Biosynthetic pathways of specialized metabolites utilize protein–protein interactions (PPIs) to facilitate metabolic flux and sequester reactive intermediates. The monoterpene indole alkaloid pathway ...
pubs.acs.org
January 9, 2026 at 10:45 PM
Protein–Protein Interactions Modulate a Key Branch Point in Monoterpene Indole Alkaloid Biosynthesis | ACS Chemical Biology pubs.acs.org/doi/full/10....
Metagenomic characterisation of fungal communities associated with Scots pine bark beetles: mechanisms of selective antagonism and monoterpene tolerance https://www.biorxiv.org/content/10.64898/2025.12.15.694374v1
December 16, 2025 at 8:16 PM
Metagenomic characterisation of fungal communities associated with Scots pine bark beetles: mechanisms of selective antagonism and monoterpene tolerance https://www.biorxiv.org/content/10.64898/2025.12.15.694374v1
Metagenomic characterisation of fungal communities associated with Scots pine bark beetles: mechanisms of selective antagonism and monoterpene tolerance https://www.biorxiv.org/content/10.64898/2025.12.15.694374v1
December 16, 2025 at 8:16 PM
Metagenomic characterisation of fungal communities associated with Scots pine bark beetles: mechanisms of selective antagonism and monoterpene tolerance https://www.biorxiv.org/content/10.64898/2025.12.15.694374v1
Researchers @ MPI for Chemical Ecology write in The ISME Journal that the symbiotic fungus of the ship-timber beetle provides abundant nutrients & produces monoterpene alcohols and acetic acid against competitors. ...
weiterlesen
weiterlesen
December 3, 2025 at 4:12 PM
Researchers @ MPI for Chemical Ecology write in The ISME Journal that the symbiotic fungus of the ship-timber beetle provides abundant nutrients & produces monoterpene alcohols and acetic acid against competitors. ...
weiterlesen
weiterlesen
Functional characterization of a novel bark-specific multi-product monoterpene synthase from the rubber tree (Hevea brasiliensis) https://pubmed.ncbi.nlm.nih.gov/41325511/
December 3, 2025 at 4:11 PM
Functional characterization of a novel bark-specific multi-product monoterpene synthase from the rubber tree (Hevea brasiliensis) https://pubmed.ncbi.nlm.nih.gov/41325511/
Researchers @ MPI for Chemical Ecology write in The ISME Journal that the symbiotic fungus of the ship-timber beetle provides abundant nutrients & produces monoterpene alcohols and acetic acid against competitors. ...
weiterlesen
weiterlesen
December 3, 2025 at 4:05 PM
Researchers @ MPI for Chemical Ecology write in The ISME Journal that the symbiotic fungus of the ship-timber beetle provides abundant nutrients & produces monoterpene alcohols and acetic acid against competitors. ...
weiterlesen
weiterlesen
Drop something MIRRORED
November 30, 2025 at 3:50 AM
Drop something MIRRORED
The #pre-print for the Australian #fieldwork we did last February is now out! We show snow gum #dieback alters #volatile emissions, especially increasing #monoterpene #emissions from damaged trunks. You can read more here: doi.org/10.22541/ess...
The fieldwork sure was one to remember! 🌿🪲☁️🦘
The fieldwork sure was one to remember! 🌿🪲☁️🦘
November 25, 2025 at 5:51 PM
The #pre-print for the Australian #fieldwork we did last February is now out! We show snow gum #dieback alters #volatile emissions, especially increasing #monoterpene #emissions from damaged trunks. You can read more here: doi.org/10.22541/ess...
The fieldwork sure was one to remember! 🌿🪲☁️🦘
The fieldwork sure was one to remember! 🌿🪲☁️🦘
A cell‐type‐specific regulon controlling monoterpene indole alkaloid biosynthesis with feedback and feedforward activation loops
Li et al.
nph.onlinelibrary.wiley.com/doi/10.1111/...
Li et al.
nph.onlinelibrary.wiley.com/doi/10.1111/...
November 11, 2025 at 2:45 AM
A cell‐type‐specific regulon controlling monoterpene indole alkaloid biosynthesis with feedback and feedforward activation loops
Li et al.
nph.onlinelibrary.wiley.com/doi/10.1111/...
Li et al.
nph.onlinelibrary.wiley.com/doi/10.1111/...
Position-specific isotope labelling gives new insights into chiral monoterpene synthesis of Norway spruce (Picea abies L.) #stableisotopes www.sciencedirect.com/science/arti...
Position-specific isotope labelling gives new insights into chiral monoterpene synthesis of Norway spruce (Picea abies L.)
Chiral forms of monoterpenes and their enantiomeric composition are of ecological significance, e.g. for plant-insect interactions. However, biosynthe…
www.sciencedirect.com
November 6, 2025 at 9:03 AM
Position-specific isotope labelling gives new insights into chiral monoterpene synthesis of Norway spruce (Picea abies L.) #stableisotopes www.sciencedirect.com/science/arti...
The group of Heribert Warzecha @tuda.bsky.social engineered Nicotiana benthamiana to produce new irregular monoterpene malonyl glucosides by co-expressing isoprenyl diphosphate synthases and key precursor enzymes — achieving record yields in plants.
👉 doi.org/10.3389/fpls.2025.1678814
👉 doi.org/10.3389/fpls.2025.1678814
Frontiers | Efficient accumulation of new irregular monoterpene malonyl glucosides in Nicotiana benthamiana achieved by co-expression of isoprenyl diphosphate synthases and substrate-producing enzymes
Irregular monoterpenes have limited natural sources but possess unique activities applicable in medicine and agriculture. To enable sustainable plant-based p...
www.frontiersin.org
November 3, 2025 at 4:22 PM
The group of Heribert Warzecha @tuda.bsky.social engineered Nicotiana benthamiana to produce new irregular monoterpene malonyl glucosides by co-expressing isoprenyl diphosphate synthases and key precursor enzymes — achieving record yields in plants.
👉 doi.org/10.3389/fpls.2025.1678814
👉 doi.org/10.3389/fpls.2025.1678814
McNeill group presentations at #AAAR2025 start with the poster session this afternoon - Katie Stevenson (2AC.11) presenting on the application of AMORE 2.0 to reducing monoterpene oxidation mechanisms @mcneill-lab.org
October 14, 2025 at 4:32 PM
McNeill group presentations at #AAAR2025 start with the poster session this afternoon - Katie Stevenson (2AC.11) presenting on the application of AMORE 2.0 to reducing monoterpene oxidation mechanisms @mcneill-lab.org
Increasing woodland cover to 19% to help reach net-zero could change the biogenic emissions from UK woodlands. @treeswithhazel.bsky.social’s latest research shows the potential scale of change by 2050 associated with different tree species mixes.
Find out more here: leaf.leeds.ac.uk/news/why-pla...
Find out more here: leaf.leeds.ac.uk/news/why-pla...
October 9, 2025 at 1:12 PM
Increasing woodland cover to 19% to help reach net-zero could change the biogenic emissions from UK woodlands. @treeswithhazel.bsky.social’s latest research shows the potential scale of change by 2050 associated with different tree species mixes.
Find out more here: leaf.leeds.ac.uk/news/why-pla...
Find out more here: leaf.leeds.ac.uk/news/why-pla...
Our two-step total synthesis of monoterpene lactones Lappaceolide A and B appears in Org. Lett. ASAPs! Kudos to our postdoc Rajanish for troubleshooting the tricky domino reaction, and to undergraduate researchers Jenna and Leevi for initial route exploration. #chemsky
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Biomimetic Total Synthesis of (±)-Lappaceolides A and B
The first total synthesis of lappaceolides A and B is achieved in two steps by using a biomimetic vinylogous-Michael–oxa-Michael domino reaction. The domino reaction proceeds with Cs2CO3 in 1,2-DCE at...
pubs.acs.org
October 2, 2025 at 6:49 AM
Our two-step total synthesis of monoterpene lactones Lappaceolide A and B appears in Org. Lett. ASAPs! Kudos to our postdoc Rajanish for troubleshooting the tricky domino reaction, and to undergraduate researchers Jenna and Leevi for initial route exploration. #chemsky
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
This study investigated the protective effects of 1,8-cineole, a natural monoterpene, against Aroclor-1254 (A1254)-induced liver toxicity in male rats. The researchers used ELISA, RT-PCR, histopathological analysis, and immunohistochemistry to evaluate the mechanisms.
September 18, 2025 at 3:41 AM
This study investigated the protective effects of 1,8-cineole, a natural monoterpene, against Aroclor-1254 (A1254)-induced liver toxicity in male rats. The researchers used ELISA, RT-PCR, histopathological analysis, and immunohistochemistry to evaluate the mechanisms.
Whole-genome identification and functional analysis of grape bHLH transcription factors: new insights into the regulation of monoterpene biosynthesis
Frontiers
www.frontiersin.org/journals/pla...
Frontiers
www.frontiersin.org/journals/pla...
Frontiers | Whole-genome identification and functional analysis of grape bHLH transcription factors: new insights into the regulation of monoterpene biosynthesis
Basic/helix-loop-helix (bHLH) transcription factors play critical roles in the regulation of plant secondary metabolism, but the molecular mechanisms involve...
www.frontiersin.org
September 18, 2025 at 12:57 AM
Whole-genome identification and functional analysis of grape bHLH transcription factors: new insights into the regulation of monoterpene biosynthesis
Frontiers
www.frontiersin.org/journals/pla...
Frontiers
www.frontiersin.org/journals/pla...
A Compact Matrix Representation for Hydrocarbon and Its Applications on Monoterpene Carbocation Rearrangement Elementary Steps https://www.biorxiv.org/content/10.1101/2025.08.23.671925v1
August 29, 2025 at 12:47 AM
A Compact Matrix Representation for Hydrocarbon and Its Applications on Monoterpene Carbocation Rearrangement Elementary Steps https://www.biorxiv.org/content/10.1101/2025.08.23.671925v1
A Compact Matrix Representation for Hydrocarbon and Its Applications on Monoterpene Carbocation Rearrangement Elementary Steps https://www.biorxiv.org/content/10.1101/2025.08.23.671925v1
August 29, 2025 at 12:47 AM
A Compact Matrix Representation for Hydrocarbon and Its Applications on Monoterpene Carbocation Rearrangement Elementary Steps https://www.biorxiv.org/content/10.1101/2025.08.23.671925v1
🍷 SPECIAL ISSUE REVIEW 🍷
✍️ Šikuten et al.
🍇 This review presents the main groups of volatile compounds in grapes, often confused with wine volatiles, alongside findings on their biosynthesis and analysis ⚗️
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
✍️ Šikuten et al.
🍇 This review presents the main groups of volatile compounds in grapes, often confused with wine volatiles, alongside findings on their biosynthesis and analysis ⚗️
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
August 18, 2025 at 2:21 PM
🍷 SPECIAL ISSUE REVIEW 🍷
✍️ Šikuten et al.
🍇 This review presents the main groups of volatile compounds in grapes, often confused with wine volatiles, alongside findings on their biosynthesis and analysis ⚗️
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
✍️ Šikuten et al.
🍇 This review presents the main groups of volatile compounds in grapes, often confused with wine volatiles, alongside findings on their biosynthesis and analysis ⚗️
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
Efficient accumulation of new irregular monoterpene malonyl glucosides in Nicotiana benthamiana achieved by co-expression of isoprenyl diphosphate synthases and substrate-producing enzymes https://www.biorxiv.org/content/10.1101/2025.08.06.668877v1
August 7, 2025 at 5:03 PM
Efficient accumulation of new irregular monoterpene malonyl glucosides in Nicotiana benthamiana achieved by co-expression of isoprenyl diphosphate synthases and substrate-producing enzymes https://www.biorxiv.org/content/10.1101/2025.08.06.668877v1
Efficient accumulation of new irregular monoterpene malonyl glucosides in Nicotiana benthamiana achieved by co-expression of isoprenyl diphosphate synthases and substrate-producing enzymes https://www.biorxiv.org/content/10.1101/2025.08.06.668877v1
August 7, 2025 at 5:03 PM
Efficient accumulation of new irregular monoterpene malonyl glucosides in Nicotiana benthamiana achieved by co-expression of isoprenyl diphosphate synthases and substrate-producing enzymes https://www.biorxiv.org/content/10.1101/2025.08.06.668877v1
Cuminaldehyde (a major volatile of cumin seeds) and eugenol (a major volatile of clove) might look similar structurally, but they have very different biosynthetic origins. One is (proposed to be) a monoterpene, while the other is a phenylpropanoid. Convergent evolution of fragrance, I guess.
August 7, 2025 at 3:21 AM
Cuminaldehyde (a major volatile of cumin seeds) and eugenol (a major volatile of clove) might look similar structurally, but they have very different biosynthetic origins. One is (proposed to be) a monoterpene, while the other is a phenylpropanoid. Convergent evolution of fragrance, I guess.
Oxford Companion to Spirits & Cocktails pg 399 contr Audrey Saunders
juniper
small, bushy, coniferous shrub with short, prickly needles. Its “berries” (soft cones) are rich in monoterpene compounds which provide fresh, sweet, piney-camphorous notes. Essential for genever, gin
#Cheers 🍸
juniper
small, bushy, coniferous shrub with short, prickly needles. Its “berries” (soft cones) are rich in monoterpene compounds which provide fresh, sweet, piney-camphorous notes. Essential for genever, gin
#Cheers 🍸
July 27, 2025 at 6:13 PM
Oxford Companion to Spirits & Cocktails pg 399 contr Audrey Saunders
juniper
small, bushy, coniferous shrub with short, prickly needles. Its “berries” (soft cones) are rich in monoterpene compounds which provide fresh, sweet, piney-camphorous notes. Essential for genever, gin
#Cheers 🍸
juniper
small, bushy, coniferous shrub with short, prickly needles. Its “berries” (soft cones) are rich in monoterpene compounds which provide fresh, sweet, piney-camphorous notes. Essential for genever, gin
#Cheers 🍸
Enzymatic epimerization of monoterpene indole alkaloids in kratom by @oconnorlab.bsky.social
From: www.nature.com/articles/s41...
#PlantScience #SecMet
From: www.nature.com/articles/s41...
#PlantScience #SecMet
Enzymatic epimerization of monoterpene indole alkaloids in kratom - Nature Chemical Biology
Monoterpene indole alkaloids are formed via a 3S stereoselective condensation between secologanin and tryptamine. Here the authors uncover the mechanism of epimerization behind uncommon 3R-containing ...
www.nature.com
July 16, 2025 at 2:58 PM
Enzymatic epimerization of monoterpene indole alkaloids in kratom by @oconnorlab.bsky.social
From: www.nature.com/articles/s41...
#PlantScience #SecMet
From: www.nature.com/articles/s41...
#PlantScience #SecMet