Soil pollution poses a serious threat to terrestrial ecosystems and human health, yet studies often focus on a handful of pollutant classes per study. Wide-scope methodologies are necessary to account for the complexity and diversity of the soil matrix and the organic micropollutant mixture of both known and novel compounds it may contain. Thus, to facilitate comprehensive monitoring of the organic micropollutant burden in soil with gas chromatography coupled with high-resolution mass spectrometry (GC-HRMS), three wide-scope methods were developed and compared: modified QuEChERS (mQuEChERS), Accelerated Solvent Extraction (ASE), and Ultrasonic Assisted Extraction (UAE). Comparison of the three methods and the final choice of the modified QuEChERS were achieved via an examination of the performance characteristics, such as the number of analytes detected, recoveries, matrix effect, and precision, through a smart validation scheme that encompassed 38 analytes belonging to diverse pollutant classes. The mQuEChERS method was then fully validated for the simultaneous quantification of 75 analytes, including pesticides, polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), polychlorinated naphthalenes (PCNs), and organochlorine pesticides (OCPs). The method’s limits of detection (MLOD) ranged from 0.04 to 2.77 μg kg−1 d.w. Linearity was demonstrated within a concentration range of 30 to 300 μg kg−1 d.w. Recoveries ranged from 70 to 120%. Method precision was deemed optimal (RSD 

Scientific Reports - Assessment of antibacterial, nematicidal and herbicidal activities of Cautleya spicata (Sm.) Baker extracts, with chemical profiling using GC-MS

Quorum Sensing is a signalling mechanism used by bacteria to regulate gene expression as a function of population density, enabling them to engage in …

Astragalus tokatensis is a local endemic species and no study exists on this species. In this study, hexane, dichloromethane, methanol and water extracts were obtained from the parts of root, leaf an...

In this study, the “Ethanol as an Internal Standard” method was employed for the quantification of volatile congeners in wines using headspace solid phase microextraction (SPME) as a way of sampling a...

Lipids contribute significantly to the flavor of cell-cultured fish meat as precursor components of flavor compounds. Here, we initially reported the …

Prostate cancer (PCa) is a major, and increasingly global, health concern with current screening and diagnostic tools’ severe limitations causing unnecessary, invasive biopsy procedures. While gas chr...

Mixtures of partially O-methylated alditol acetate standards of allose, altrose, gulose and talose were synthesised. Methyl glycosides of each sugar w…

Dissipation behavior of pyridalyl was determined on cabbage crop following two applications of pyridalyl @ 50 (X), 62.5 (1.25X), and 100 g a.i. ha−1 (2X). QuEChERS method along with gas chromatograph...

【Pharmacol Res Perspect】<AbstractText>Jatropha gossypifolia L., a member of the Euphorbiaceae family, has been traditionally us...

A method based on headspace solid-phase microextraction fiber derivatization (HS-SPME-FD) coupled with gas chromatography-triple quadrupole mass spect…

A gas chromatography-tandem mass technique for simultaneous determination of four fluoroquinolone residues in poultry meat and pork was perfect. Trime…