Wen Jiang MD, PhD
@wenjiang-nano.bsky.social
Radiation oncologist and physician scientist
Reposted by Wen Jiang MD, PhD
How do mRNA vaccines help fight cancer?
A @nature.com paper today tells the story, one with big implications, as reviewed here
erictopol.substack.com/p/how-mrna-v...
A @nature.com paper today tells the story, one with big implications, as reviewed here
erictopol.substack.com/p/how-mrna-v...
How mRNA Vaccines Can Help Fight Cancer
Turning "cold" tumors "hot"
erictopol.substack.com
October 22, 2025 at 3:19 PM
How do mRNA vaccines help fight cancer?
A @nature.com paper today tells the story, one with big implications, as reviewed here
erictopol.substack.com/p/how-mrna-v...
A @nature.com paper today tells the story, one with big implications, as reviewed here
erictopol.substack.com/p/how-mrna-v...
Excited to share work led by our own Adam Grippin (soon to be faculty) @natureportfolio.nature.com showing that non -neoantigenic #covid #mrna vaccine can promote antitumor immune response and augment checkpoint blockade. @mdanderson.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade - Nature
mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to immune checkpoint inhibitors.
www.nature.com
October 22, 2025 at 4:46 PM
Excited to share work led by our own Adam Grippin (soon to be faculty) @natureportfolio.nature.com showing that non -neoantigenic #covid #mrna vaccine can promote antitumor immune response and augment checkpoint blockade. @mdanderson.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Wen Jiang MD, PhD
This week's new issue of #ScienceTranslationalMedicine is out now!
An experimental trial could reshape patient monitoring and therapy research in glioblastoma, RNA vaccines can protect large animals from new strains of H5N1, and more. https://scim.ag/3KYkXvi
An experimental trial could reshape patient monitoring and therapy research in glioblastoma, RNA vaccines can protect large animals from new strains of H5N1, and more. https://scim.ag/3KYkXvi
October 8, 2025 at 9:00 PM
This week's new issue of #ScienceTranslationalMedicine is out now!
An experimental trial could reshape patient monitoring and therapy research in glioblastoma, RNA vaccines can protect large animals from new strains of H5N1, and more. https://scim.ag/3KYkXvi
An experimental trial could reshape patient monitoring and therapy research in glioblastoma, RNA vaccines can protect large animals from new strains of H5N1, and more. https://scim.ag/3KYkXvi
Our latest article is online @natcancer.nature.com describing the application of #nanotechnology in #immuno-oncology. A great effort led by Adam Grippin, our star Holman resident and soon to be Physician Scientist. @bettykimmdphd.bsky.social @mdanderson.bsky.social @eileenparkes.bsky.social
Nanotechnology for immuno-oncology - Nature Cancer
Kim and colleagues provide an overview of the current state of the art of nanomaterials and their application in immuno-oncology, discussing preclinical development and the clinical landscape.
www.nature.com
August 7, 2025 at 10:49 AM
Our latest article is online @natcancer.nature.com describing the application of #nanotechnology in #immuno-oncology. A great effort led by Adam Grippin, our star Holman resident and soon to be Physician Scientist. @bettykimmdphd.bsky.social @mdanderson.bsky.social @eileenparkes.bsky.social
Reposted by Wen Jiang MD, PhD
My colleagues at Nature Biomedical Engineering @natbiomedeng.nature.com are hiring an associate or senior editor. Ideal applicant will have expertise in immunology, immunotherapy, or immuno-oncology.
Please feel to ask me questions!
springernature.wd3.myworkdayjobs.com/SpringerNatu...
Please feel to ask me questions!
springernature.wd3.myworkdayjobs.com/SpringerNatu...
Associate or Senior Editor, Nature Biomedical Engineering
Job Title: Associate or Senior Editor, Nature Biomedical Engineering Organization: Nature Portfolio Location: New York, Jersey City, Shanghai or Beijing – Hybrid Working Closing date: August 20, 2025 ...
springernature.wd3.myworkdayjobs.com
July 30, 2025 at 6:21 PM
My colleagues at Nature Biomedical Engineering @natbiomedeng.nature.com are hiring an associate or senior editor. Ideal applicant will have expertise in immunology, immunotherapy, or immuno-oncology.
Please feel to ask me questions!
springernature.wd3.myworkdayjobs.com/SpringerNatu...
Please feel to ask me questions!
springernature.wd3.myworkdayjobs.com/SpringerNatu...
Congrats to Adam Grippin, a resident in the radiation oncology program @mdanderson.bsky.social , and soon to be physician scientist, on his latest commentary in @natrevimmunol.nature.com, highlighting a new cell surface mapping technique with implication in understanding immune cell functions.
Mitochondrial proteins go public and novel interactions: insights from surfaceome mapping - Nature Reviews Immunology
A recent preprint by Floyd et al. presents the most comprehensive mapping to date of the human lymphocyte ‘surfaceome’.
www.nature.com
July 23, 2025 at 7:20 PM
Congrats to Adam Grippin, a resident in the radiation oncology program @mdanderson.bsky.social , and soon to be physician scientist, on his latest commentary in @natrevimmunol.nature.com, highlighting a new cell surface mapping technique with implication in understanding immune cell functions.
Congrats on a new commentary from Ben & @bettykimmdphd.bsky.social @natrevimmunol.nature.com on a preprint detailing a pan-cancer antigen atlas for human cancers. @mdanderson.bsky.social
Uncovering the hidden landscape of tumour antigens - Nature Reviews Immunology
A preprint by Li et al. presents a comprehensive pan-cancer atlas of tumour-specific peptides that markedly expands the known tumour antigen repertoire.
www.nature.com
June 12, 2025 at 12:59 PM
Congrats on a new commentary from Ben & @bettykimmdphd.bsky.social @natrevimmunol.nature.com on a preprint detailing a pan-cancer antigen atlas for human cancers. @mdanderson.bsky.social
Our latest publication led by Yifan Wang is now @acs.org on developing a generative #AI #LLM to help design #nanomedicine. @mdanderson.bsky.social @bettykimmdphd.bsky.social
A Generative Artificial Intelligence Copilot for Biomedical Nanoengineering
The recent success of large language models (LLMs) in performing natural language processing tasks has increased interest in applying generative artificial intelligence (AI) to scientific research. Ho...
pubs.acs.org
May 14, 2025 at 8:47 PM
Our latest publication led by Yifan Wang is now @acs.org on developing a generative #AI #LLM to help design #nanomedicine. @mdanderson.bsky.social @bettykimmdphd.bsky.social
Reposted by Wen Jiang MD, PhD
I am thrilled to share that the first preprint from my lab is now available on bioRxiV! In this study, our team elucidates the role of autocrine ligands in the aberrant behavior of oncogene-driven lung cancer.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
BRAFV600E-Driven Lung Tumorigenesis Requires Ligand-Mediated Activation of ERBB Receptor Signaling
Secretion of ligands of the human epidermal growth factor (EGFR) family of receptors or erythroblastic leukemia viral oncogene family (ERBB1-4) is a feature common to many cancer cells. However, our u...
www.biorxiv.org
May 9, 2025 at 8:16 PM
I am thrilled to share that the first preprint from my lab is now available on bioRxiV! In this study, our team elucidates the role of autocrine ligands in the aberrant behavior of oncogene-driven lung cancer.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Wen Jiang MD, PhD
NEW Preprint Watch from Annette Wu & @wenjiang-nano.bsky.social @preprintclub.bsky.social reporting on @biorxiv-immuno.bsky.social preprint by @colinraposo.bsky.social et al. showing that checkpoint blockade drives expansion of exhausted T cell clones that develop functional memory
rdcu.be/ek1kY
rdcu.be/ek1kY
Progenitor exhausted T cells contribute to the formation of immunological memory
Nature Reviews Immunology - A preprint by Raposo et al. shows that immune checkpoint blockade drives the expansion of certain clones of exhausted T cells that can develop into functional memory...
rdcu.be
May 7, 2025 at 11:19 AM
NEW Preprint Watch from Annette Wu & @wenjiang-nano.bsky.social @preprintclub.bsky.social reporting on @biorxiv-immuno.bsky.social preprint by @colinraposo.bsky.social et al. showing that checkpoint blockade drives expansion of exhausted T cell clones that develop functional memory
rdcu.be/ek1kY
rdcu.be/ek1kY
Sharing the latest commentary by our amazing PhD student Annette Wu @natrevimmunol.nature.com previewing exciting work from @stanfordmedicine.bsky.social on the formation of memory T cells in the setting of chronic stimulation. @mdanderson.bsky.social
Progenitor exhausted T cells contribute to the formation of immunological memory - Nature Reviews Immunology
A preprint by Raposo et al. shows that immune checkpoint blockade drives the expansion of certain clones of exhausted T cells that can develop into functional memory cells after clearance of chronic v...
www.nature.com
May 6, 2025 at 5:22 PM
Sharing the latest commentary by our amazing PhD student Annette Wu @natrevimmunol.nature.com previewing exciting work from @stanfordmedicine.bsky.social on the formation of memory T cells in the setting of chronic stimulation. @mdanderson.bsky.social
Greatly enjoyed @twanlammers.bsky.social visiting Houston! Enjoying some classic Texan protein in preparation for his high caloric burning seminar.
April 7, 2025 at 5:07 PM
Greatly enjoyed @twanlammers.bsky.social visiting Houston! Enjoying some classic Texan protein in preparation for his high caloric burning seminar.
Our latest paper in collaboration with @jacques-lux.bsky.social describing using #US to activate #sting for #cancerimmunotherapy is now online in AdvScience. @mdanderson.bsky.social @utswtxid.bsky.social
Targeted STING Activation Using Modified Ultrasound‐Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microb...
advanced.onlinelibrary.wiley.com
March 26, 2025 at 1:43 PM
Our latest paper in collaboration with @jacques-lux.bsky.social describing using #US to activate #sting for #cancerimmunotherapy is now online in AdvScience. @mdanderson.bsky.social @utswtxid.bsky.social
Research briefing describing our latest paper is now online @naturecancer.bsky.social rdcu.be/ecf1I @mdanderson.bsky.social @ackoongmdphd.bsky.social @bettykimmdphd.bsky.social
An antibody–toxin conjugate enhances innate immune cell responses in tumors
Nature Cancer - Traditional antibody–toxin conjugates (ATCs) are designed to target and destroy cancer cells. We present an ATC that acts on innate immune cells to promote tumor-cell...
rdcu.be
March 5, 2025 at 1:14 PM
Research briefing describing our latest paper is now online @naturecancer.bsky.social rdcu.be/ecf1I @mdanderson.bsky.social @ackoongmdphd.bsky.social @bettykimmdphd.bsky.social
Reposted by Wen Jiang MD, PhD
MD Anderson researchers have developed a novel antibody toxin-conjugate that’s not designed to kill the cancer cells directly.
Read how this new approach is designed to trigger the body's natural immune response instead: bit.ly/4bhtToM #EndCancer
Read how this new approach is designed to trigger the body's natural immune response instead: bit.ly/4bhtToM #EndCancer
MD Anderson researchers develop novel antibody-toxin conjugate
Researchers at The University of Texas MD Anderson Cancer Center have developed a novel antibody-toxin conjugate (ATC) designed to stimulate immune-mediated eradication of tumors. According to preclin...
www.mdanderson.org
February 25, 2025 at 3:19 PM
MD Anderson researchers have developed a novel antibody toxin-conjugate that’s not designed to kill the cancer cells directly.
Read how this new approach is designed to trigger the body's natural immune response instead: bit.ly/4bhtToM #EndCancer
Read how this new approach is designed to trigger the body's natural immune response instead: bit.ly/4bhtToM #EndCancer
Our newest article is online @naturecancer.bsky.social A new antibody drug conjugate that doesn’t kill tumor cells but rely on immune system to eradicate cancer. @bettykimmdphd.bsky.social @mdanderson.bsky.social
An antibody–toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy
Nature Cancer - Schrank et al. report the design and characterization of an antibody–toxin conjugate targeting CD47, promoting anti-tumor immunity in preclinical cancer models.
www.nature.com
February 25, 2025 at 1:43 PM
Our newest article is online @naturecancer.bsky.social A new antibody drug conjugate that doesn’t kill tumor cells but rely on immune system to eradicate cancer. @bettykimmdphd.bsky.social @mdanderson.bsky.social
Reposted by Wen Jiang MD, PhD
MD Anderson is grateful to the Cancer Prevention and Research Institute of Texas for providing nearly $23 million to support our ongoing research and faculty recruitment.
Read about the research it will benefit: brnw.ch/21wQOF9 #EndCancer
Read about the research it will benefit: brnw.ch/21wQOF9 #EndCancer
MD Anderson receives nearly $23 million in CPRIT funding for cancer research, faculty recruitment
The University of Texas MD Anderson Cancer Center today was awarded nearly $23 million from the Cancer Prevention and Research Institute of Texas (CPRIT) in support of 20 cancer research projects to a...
brnw.ch
February 19, 2025 at 7:59 PM
MD Anderson is grateful to the Cancer Prevention and Research Institute of Texas for providing nearly $23 million to support our ongoing research and faculty recruitment.
Read about the research it will benefit: brnw.ch/21wQOF9 #EndCancer
Read about the research it will benefit: brnw.ch/21wQOF9 #EndCancer
Hanging out with old doctoral study advisor in Singapore. Talking about science over beautiful scenery and amazing food.
February 21, 2025 at 4:48 AM
Hanging out with old doctoral study advisor in Singapore. Talking about science over beautiful scenery and amazing food.
Reposted by Wen Jiang MD, PhD
Understanding how nanoparticles interact with biological systems is crucial for the development and implementation of nanoparticles in clinical settings. This article explores multi-omics approaches to decipher the interactions of nanoparticles and biological systems:
https://go.nature.co...
https://go.nature.co...
Multi-omics approaches to decipher the interactions of nanoparticles and biological systems - Nature Reviews Bioengineering
The interactions of nanoparticles with the body are dynamic and complex. This Perspective examines the application of different multi-omics tools to investigate nano–bio interactions in vitro and in vivo.
go.nature.com
December 19, 2024 at 2:38 PM
Understanding how nanoparticles interact with biological systems is crucial for the development and implementation of nanoparticles in clinical settings. This article explores multi-omics approaches to decipher the interactions of nanoparticles and biological systems:
https://go.nature.co...
https://go.nature.co...
Reposted by Wen Jiang MD, PhD
Congrats to @wenjiang-nano.bsky.social! Well deserved recognition. @MDAndersonNews #endcancer #radonc
January 12, 2025 at 1:15 PM
Congrats to @wenjiang-nano.bsky.social! Well deserved recognition. @MDAndersonNews #endcancer #radonc
Finishing up 2024 with our latest paper in Nature Rev Bioengineering on using multiomic tools to study bio-nano interactions. @bettykimmdphd.bsky.social @mdanderson.bsky.social
Multi-omics approaches to decipher the interactions of nanoparticles and biological systems - Nature Reviews Bioengineering
The interactions of nanoparticles with the body are dynamic and complex. This Perspective examines the application of different multi-omics tools to investigate nano–bio interactions in vitro and in v...
www.nature.com
December 18, 2024 at 2:04 PM
Finishing up 2024 with our latest paper in Nature Rev Bioengineering on using multiomic tools to study bio-nano interactions. @bettykimmdphd.bsky.social @mdanderson.bsky.social
Reposted by Wen Jiang MD, PhD
Grateful for this holiday season. Especially for our family, friends, mentors and our trainees who fills us with joy, love, laughter and kindness. Our first attempt at roasting a turkey finally became reality at 9pm. #Thankful #SomeonesSmoked&RaginCajunTurkiesWereBetter
@wenjiang-nano.bsky.social
@wenjiang-nano.bsky.social
November 29, 2024 at 4:33 PM
Grateful for this holiday season. Especially for our family, friends, mentors and our trainees who fills us with joy, love, laughter and kindness. Our first attempt at roasting a turkey finally became reality at 9pm. #Thankful #SomeonesSmoked&RaginCajunTurkiesWereBetter
@wenjiang-nano.bsky.social
@wenjiang-nano.bsky.social
Reposted by Wen Jiang MD, PhD
Great time tonight with guest Dolores Hambardzumyan and our colleagues Jason Schenkel, @wenjiang-nano.bsky.social
and #JPAI members @pamsharmamdphd.bsky.social @jimallisonphd.bsky.social
Xi Chen @mdanderson.bsky.social
#myeloid #GBM #endcancer
and #JPAI members @pamsharmamdphd.bsky.social @jimallisonphd.bsky.social
Xi Chen @mdanderson.bsky.social
#myeloid #GBM #endcancer
November 26, 2024 at 3:55 AM
Great time tonight with guest Dolores Hambardzumyan and our colleagues Jason Schenkel, @wenjiang-nano.bsky.social
and #JPAI members @pamsharmamdphd.bsky.social @jimallisonphd.bsky.social
Xi Chen @mdanderson.bsky.social
#myeloid #GBM #endcancer
and #JPAI members @pamsharmamdphd.bsky.social @jimallisonphd.bsky.social
Xi Chen @mdanderson.bsky.social
#myeloid #GBM #endcancer
Reposted by Wen Jiang MD, PhD
www.nature.com/articles/s41...
Sharing our latest review article to highlight the importance of appropriately developing combination strategies for immune checkpoint therapy. Grateful for working with 3 brilliant scientists: Sangeeta Goswami, Kristen Pauken & Linghua Wang
Sharing our latest review article to highlight the importance of appropriately developing combination strategies for immune checkpoint therapy. Grateful for working with 3 brilliant scientists: Sangeeta Goswami, Kristen Pauken & Linghua Wang
Next-generation combination approaches for immune checkpoint therapy - Nature Immunology
In this Review, Sharma and colleagues describe the current landscape of combination therapies and discuss requirements for the development of effective combination strategies.
www.nature.com
November 25, 2024 at 8:43 PM
www.nature.com/articles/s41...
Sharing our latest review article to highlight the importance of appropriately developing combination strategies for immune checkpoint therapy. Grateful for working with 3 brilliant scientists: Sangeeta Goswami, Kristen Pauken & Linghua Wang
Sharing our latest review article to highlight the importance of appropriately developing combination strategies for immune checkpoint therapy. Grateful for working with 3 brilliant scientists: Sangeeta Goswami, Kristen Pauken & Linghua Wang