Wayo Matsushima
wayomayo.bsky.social
Wayo Matsushima
@wayomayo.bsky.social
EMBO/JSPS postdoctoral fellow in the Trono lab, EPFL. Studying regulatory evolution driven by transposable elements.
Pinned
New preprint of my postdoc work! We found a novel group of zinc-finger proteins that rapidly evolved in a lineage-specific manner to repress regulatory activities of transposon-derived sequences through anchoring nucleosomes. #TEsky

biorxiv.org/content/10.110…
Reposted by Wayo Matsushima
Did transposable elements shape brain evolution — and if so, which ones, and in which cell states and lineages? Led by @tyamadat.bsky.social, we explored this question in cerebellum development using sequence-based deep learning models!
www.biorxiv.org/content/10.1...
October 16, 2025 at 10:01 PM
Reposted by Wayo Matsushima
It is with great sadness that we share the news of the death of our founder, colleague, mentor and friend, Professor Sir John Gurdon. His vision and dedication will continue to inspire generations of scientists.
🔗 www.gurdon.cam.ac.uk/nobel-laurea...
October 8, 2025 at 1:15 PM
Reposted by Wayo Matsushima
“For Gurdon to continue in biology would be a complete waste of time both for him and for those who would have to teach him”

He proved them wrong! RIP John Gurdon

www.cell.com/current-biol...
John Gurdon
John Gurdon is at the Wellcome Trust/Cancer Research UK Institute of Cancer and Developmental Biology in Cambridge. Educated at Eton and Christ Church, Oxford, he changed from classics to zoology. Dur...
www.cell.com
October 7, 2025 at 4:21 PM
Reposted by Wayo Matsushima
⚡⚡Excited to announce I'll be starting my lab at the Max Planck Institute of Molecular Genetics (@molgen.mpg.de) in Berlin in December! Leaving sunny California to join a fantastic environment with colleagues who do super cool work.
🔬🦠I'm hiring at all levels! 🔬🦠Check: www.molgen.mpg.de/fueyo-lab
October 6, 2025 at 1:46 PM
Reposted by Wayo Matsushima
Do you research endogenous retroviruses (ERVs) or want to learn more about them? 🧬🤔

Consider presenting at or attending AuusiERV - an inaugural online symposium for ERV research in Australia 🇦🇺 (and abroad) 🗺️

Abstracts due 1st October!

events.humanitix.com/aussierv-2025

#ERV #retrovirus
AussiERV 2025
AussiERV: Australia’s first symposium dedicated to endogenous retroviruses. Join us for this one-day virtual event on November 7th!
events.humanitix.com
September 27, 2025 at 7:28 AM
Reposted by Wayo Matsushima
📣 Our department is hiring an Assistant Professor in Evolutionary Cell and Molecular Biology to join the @weillinstitute.bsky.social PLS spread the word!
academicjobsonline.org/ajo/jobs/30607
Cornell University, Molecular Biology & Genetics
Job #AJO30607, WDR-00055221 Assistant Professor, Molecular Biology & Genetics, Cornell University, Ithaca, New York, US
academicjobsonline.org
September 23, 2025 at 12:50 PM
Reposted by Wayo Matsushima
🚀 Looking for a Bioinformatician / Data Scientist to join our crew and explore regeneration through single-cell genomics & evolutionary biology! @mpi-bio-fml.bsky.social
📩 Questions? Contact us ✉️
🔗 Apply here: www.mpg.de/25243280/bio...
Bioinformatician / Data Scientist (m/f/d)
Bioinformatician / Data scientist position in the Aztekin Lab focusing on Structural Regeneration and support the working group together with the other members
www.mpg.de
September 15, 2025 at 6:58 AM
Reposted by Wayo Matsushima
I am excited to share that I will join the Friedrich Miescher Institute @fmiscience.bsky.social in Basel as a group leader, starting my lab in March 2026 🎉

We will explore cell fate regulation during organogenesis, with a focus on how cell elimination underlies the emergence of functional tissues.
August 25, 2025 at 5:21 PM
Reposted by Wayo Matsushima
Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature Genetics
Activation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype c...
www.nature.com
July 9, 2025 at 10:05 AM
Reposted by Wayo Matsushima
🧬🌽 Happy Transposon Day! 🌽🧬

Today we celebrate the birthday of Barbara McClintock - scientist extraordinaire and discoverer of jumping genes. Still the only woman to have an unshared Nobel Prize in the biomedical sciences #TransposonDay2025
June 16, 2025 at 3:14 PM
Reposted by Wayo Matsushima
Come to Lund! We are looking for a postdoc to join the team. #transposons #epigenetics
April 17, 2025 at 12:29 PM
Reposted by Wayo Matsushima
Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab!

Thankful for any retweet! 🫶

imba.onlyfy.jobs/job/l6u2m980
March 20, 2025 at 12:13 PM
New preprint of my postdoc work! We found a novel group of zinc-finger proteins that rapidly evolved in a lineage-specific manner to repress regulatory activities of transposon-derived sequences through anchoring nucleosomes. #TEsky

biorxiv.org/content/10.110…
March 10, 2025 at 8:49 AM
Thank you for this fantastic opportunity! Hope you’ll find the elements even stranger after my talk.
Next week on March 6th, we welcome @wayomayo.bsky.social as the latest guest in our Max Planck Seminar Series.

Wayo is @embo.org Postdoc in the Trono Lab, EPFL and we look forward to an interesting talk in which he opens up the (human) genome and its treasure trove of strange features: TEs.
March 3, 2025 at 8:52 AM
Reposted by Wayo Matsushima
Very excited to share our paper on Gene and Transposable Element expression in mammalian preimplantation development, online today! www.cell.com/cell/fulltex...
A short thread to highlight some of our findings 🧵
January 20, 2025 at 8:29 PM
Reposted by Wayo Matsushima
🚨Why can’t mammals regenerate legs or arms like frog tadpoles or salamanders?
Our preprint tackles (part of) this BIG question with surprising findings about oxygen sensing
🔗 www.biorxiv.org/content/10.1...
Happy New Year, everyone! 🎉
🐭 vs 🐸 #evodevo #regenerative #cellbio 🧵👇
January 6, 2025 at 8:37 AM