Timothy Saunders
timesaunders.bsky.social
Timothy Saunders
@timesaunders.bsky.social
Professor at Warwick Medical School interested in how complex shape emerges during embryo development. Will work on anything that can be imaged live :)
Major pet conference peeve - speakers not speaking to time. It shortens breaks, reduces chances to engage ECRs and sets a bad precedent. Typically the bigger the name, the worse the timing.
March 27, 2025 at 10:40 AM
Reposted by Timothy Saunders
Cells “speed date” to find their perfect neighbors when forming tissues. This marks a pivotal step in creating functional organs, like in this early heart development illustrated in a fly larvae.

Learn more: www.cell.com/biophysj/ful...

@timesaunders.bsky.social
@biophysj.bsky.social
March 12, 2025 at 8:24 PM
Reposted by Timothy Saunders
👀 Looking for a Master Program in Physics of Life? Preferably free? Maybe in a collaborative and interdisciplinary environment? Check this out👇🏻
Scientists, please share!🔬

Explore living systems through a physics lens. The #Biophysics MSc at @cmcb-tud.bsky.social opens applications on 1st April 🗓️ Taught entirely in English, with no tuition fees!

Learn more: physics-of-life.tu-dresden.de/career-educa...

#Physics #Masters #MSc #FreeTuition
March 13, 2025 at 11:05 AM
There’s been exciting work recently linking ideas from topology to biological systems. This has ranged from bird flocking (www.pnas.org/doi/full/10....), to gene networks (www.pnas.org/doi/full/10....), and now how nuclei pack in the Drosophila blastocyst (www.nature.com/articles/s41...).
Geometry of gene regulatory dynamics | PNAS
Embryonic development leads to the reproducible and ordered appearance of complexity from egg to adult. The successive differentiation of different...
www.pnas.org
March 13, 2025 at 11:02 AM
Enjoyed doing this interview. Hope it's helpful for a more general audience.
March 12, 2025 at 8:17 PM
Latest lab paper is out :)

eur01.safelinks.protection.outlook.com?url=https%3A...

With Sham Tlili, we show that a surprisingly simple equilibrium physics model can explain the highly dynamic process of cell matching in the heart.
ScienceDirect.com | Science, health and medical journals, full text articles and books.
eur01.safelinks.protection.outlook.com
March 12, 2025 at 3:06 PM
Reposted by Timothy Saunders
Excited to announce that we will be holding another #mechanobiology across scales symposium this year in beautiful Awaji Island #Japan! We have a star-studded lineup of speakers and it's free participation (free accommodation and food!)! Register here: www.igm.hokudai.ac.jp/85th-fujihar...
January 21, 2025 at 7:00 AM
Read about my amazing PhD student Ryan. Many thanks to CoB for hosting him for 3 months
December 16, 2024 at 5:25 PM
Reposted by Timothy Saunders
Since I have so many new friends 😄, I thought I'd advertise this. Together with @pritiagarwal.bsky.social and Lance Davidson, we run a Developmental Mechanics seminar series on Zoom (originally started by Ronen Zaidel-Bar). This coming Thursday, we have our last session for 2024. Join us!!
November 19, 2024 at 4:54 PM
Tweetorial continued -unable to post more on the previous one:
(ii) Bicoid could be produced in the oocyte, leading to early distribution of Bicoid (PMID: 28296637). (iii) Bicoid may not need to be degraded;dilution by nuclei could be sufficient to generate a gradient (PMID: 18001703) (10/22)
November 17, 2024 at 8:23 PM
Our new focuses on translation of Bicoid during early Drosophila development (www.biorxiv.org/content/10.1...). We answer precisely when and where bicoid mRNA is translated. This helps us build an improved model of gradient formation. But, before going into results, first some background… (1/22)
Regulation of bicoid mRNA throughout oogenesis and early embryogenesis impacts protein gradient formation
The transcription factor Bicoid (Bcd) establishes patterning in the early Drosophila blastocyst through its graded concentration along the anterior-posterior (AP) axis. bcd mRNA is maternally deposite...
www.biorxiv.org
November 17, 2024 at 8:23 PM
One thing I really liked about SciTwitter were the “tweetorials” on the latest papers – these really helped get a grip on new work, and also opened up potential research avenues that I would have otherwise missed. In this vein, I am about to try something similar here on BlueSky.
November 17, 2024 at 8:10 PM
Amazed by the sudden increase in activity here following a certain event. Hopefully a strong community can build
November 8, 2024 at 8:49 AM
A quick reminder that if you're n=2 SEM is meaningless. SEM is not a "trick" to make your error bars look smaller.
June 2, 2024 at 5:39 PM
Really excited to have the Warwick-Cambridge Meeting on quantitative cell biology today at Warwick.
warwick.ac.uk/fac/sci/med/....
warwick-cambridge_quantitative_cell
This two-day meeting will focus on Quantitative Cell and Developmental Biology. We will bring expertise from across scales, combining people working on subcellular cell biology through to tissue scale...
warwick.ac.uk
May 16, 2024 at 8:50 AM
BSDB 2024. As usual, such a fun and welcoming meeting
April 16, 2024 at 12:42 PM
My final (☹️) paper with Ivo Telley now out - doi.org/10.7554/eLif...
I felt the elife system worked well - first time publishing there since the changed model. Good to have different approaches- nothing is perfect.
March 4, 2024 at 9:59 AM
About to see Stornoway. My first gig since before I started my lab 😱
February 14, 2024 at 8:20 PM
Really happy to see this out:

journals.biologists.com/dev/article/...

We use FCS to reveal that Bicoid dynamics vary spatially across the Drosophila embryo. We demonstrate this can explain previous observations about gradient extent and time scale of formation.
February 13, 2024 at 3:58 PM
Just back from trip to Singapore. Realise I miss the place - a lot of fond memories. It was great catching up with people at NUS, NTU and A*Star
January 15, 2024 at 11:16 AM
Day started with OneDrive deciding to delete >10,000files. It kept all the folders, just deleted the content 😭 Thankfully able to restore, but now have duplicates of all my folders - one empty and one with the actual contents.
December 15, 2023 at 10:00 AM
Finally decided to move off the other site. Hope the science community finds a good home soon (hopefully here as put the effort to join and I'm too lazy to change again soon)
November 16, 2023 at 7:42 PM