Pinned
James Thaventhiran
@thav-lab.bsky.social
· Nov 17
Did frame-shifting shift our safety assessment?
YouTube video by Debunk the Funk with Dr. Wilson
www.youtube.com
As a way of an introduction, this video provides a reasonable description of some of our recent research. www.youtube.com/watch?v=rCW3...
The paper can be accessed here: www.nature.com/articles/s41...
#ImmunoSky
The paper can be accessed here: www.nature.com/articles/s41...
#ImmunoSky
Reposted by James Thaventhiran
Will take a spell for foreign bond holders to fully digest this. What just happened is so abnormal that fund managers cannot fully digest it for days. Things just broke that can’t be fixed.
August 26, 2025 at 12:35 AM
Will take a spell for foreign bond holders to fully digest this. What just happened is so abnormal that fund managers cannot fully digest it for days. Things just broke that can’t be fixed.
Is it wrong that I feel so much pride in my lab making cakes like this for our cake days?
August 4, 2025 at 2:27 PM
Is it wrong that I feel so much pride in my lab making cakes like this for our cake days?
Reposted by James Thaventhiran
#NewResearch
🚨Out now!
Human gut bacteria bioaccumulate forever chemicals, in intracellular aggregates and colonization of gnotobiotic mice with these bioaccumulating bacteria increases faecal PFAS excretion. @kiranrpatil.bsky.social
#MicroSky #MicrobiomeSky 🦠
www.nature.com/articles/s41...
🚨Out now!
Human gut bacteria bioaccumulate forever chemicals, in intracellular aggregates and colonization of gnotobiotic mice with these bioaccumulating bacteria increases faecal PFAS excretion. @kiranrpatil.bsky.social
#MicroSky #MicrobiomeSky 🦠
www.nature.com/articles/s41...
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances - Nature Microbiology
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances (PFAS), commonly known as forever chemicals, in intracellular aggregates. Colonization of gnotobiotic mice with bioaccumulating bac...
www.nature.com
July 1, 2025 at 3:18 PM
#NewResearch
🚨Out now!
Human gut bacteria bioaccumulate forever chemicals, in intracellular aggregates and colonization of gnotobiotic mice with these bioaccumulating bacteria increases faecal PFAS excretion. @kiranrpatil.bsky.social
#MicroSky #MicrobiomeSky 🦠
www.nature.com/articles/s41...
🚨Out now!
Human gut bacteria bioaccumulate forever chemicals, in intracellular aggregates and colonization of gnotobiotic mice with these bioaccumulating bacteria increases faecal PFAS excretion. @kiranrpatil.bsky.social
#MicroSky #MicrobiomeSky 🦠
www.nature.com/articles/s41...
Honoured to receive this prize alongside an inspiring group of scientists. This will support our work to improve mRNA therapies for precision medicine. #mRNA #immunoSky #Science
We are very proud to introduce our brand new 2025 #ListerFellows! This year there are eight Prize recipients. lister-institute.org.uk/a-warm-welco...
June 19, 2025 at 11:23 AM
Honoured to receive this prize alongside an inspiring group of scientists. This will support our work to improve mRNA therapies for precision medicine. #mRNA #immunoSky #Science
Reposted by James Thaventhiran
We are very proud to introduce our brand new 2025 #ListerFellows! This year there are eight Prize recipients. lister-institute.org.uk/a-warm-welco...
June 19, 2025 at 11:08 AM
We are very proud to introduce our brand new 2025 #ListerFellows! This year there are eight Prize recipients. lister-institute.org.uk/a-warm-welco...
Really excited to join this great group of people. How wonderful that there are funding schemes like this that allow us to pursue exciting new directions. lister-institute.org.uk/a-warm-welco...
A warm welcome to our 2025 Lister Fellows – Lister Institute
lister-institute.org.uk
June 19, 2025 at 11:07 AM
Really excited to join this great group of people. How wonderful that there are funding schemes like this that allow us to pursue exciting new directions. lister-institute.org.uk/a-warm-welco...
🚀 Surprised yourself with your exam results? We’re recruiting Research Assistants eager to gain hands-on experience and boost their research careers. Apply now and join a team making breakthroughs in immunology, mRNA therapeutics, cancer, and vaccine research
#ImmunoSky
www.jobs.cam.ac.uk/job/51446/
#ImmunoSky
www.jobs.cam.ac.uk/job/51446/
Research Assistant (Fixed Term) x 2 - Job Opportunities - University of Cambridge
Research Assistant (Fixed Term) x 2 in the MRC Toxicology Unit at the University of Cambridge.
www.jobs.cam.ac.uk
June 2, 2025 at 8:03 PM
🚀 Surprised yourself with your exam results? We’re recruiting Research Assistants eager to gain hands-on experience and boost their research careers. Apply now and join a team making breakthroughs in immunology, mRNA therapeutics, cancer, and vaccine research
#ImmunoSky
www.jobs.cam.ac.uk/job/51446/
#ImmunoSky
www.jobs.cam.ac.uk/job/51446/
Rob passed his PhD viva and seams to pleased to receive the lab Cake tin and cake!
December 20, 2024 at 1:46 PM
Rob passed his PhD viva and seams to pleased to receive the lab Cake tin and cake!
My postdoc let the PhD student order some media for our T cell culture. Any ideas what to do with this?
December 11, 2024 at 2:21 PM
My postdoc let the PhD student order some media for our T cell culture. Any ideas what to do with this?
Reposted by James Thaventhiran
A @science.org First Release:
@tommyz626.bsky.social, Wei Zhou, @junyuecao.bsky.social & colleagues present #PanSci, a #SingleCell #atlas profiling >20 million cells from 623 #mouse tissues across various #ages & #genotypes w/ a focus on regulatory roles of #ImmuneSystem on #aging !
@tommyz626.bsky.social, Wei Zhou, @junyuecao.bsky.social & colleagues present #PanSci, a #SingleCell #atlas profiling >20 million cells from 623 #mouse tissues across various #ages & #genotypes w/ a focus on regulatory roles of #ImmuneSystem on #aging !
A panoramic view of cell population dynamics in mammalian aging
To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome atlas profiling over 20 million cells from 623 mouse tissues across different life stages, se...
www.science.org
November 29, 2024 at 2:22 PM
A @science.org First Release:
@tommyz626.bsky.social, Wei Zhou, @junyuecao.bsky.social & colleagues present #PanSci, a #SingleCell #atlas profiling >20 million cells from 623 #mouse tissues across various #ages & #genotypes w/ a focus on regulatory roles of #ImmuneSystem on #aging !
@tommyz626.bsky.social, Wei Zhou, @junyuecao.bsky.social & colleagues present #PanSci, a #SingleCell #atlas profiling >20 million cells from 623 #mouse tissues across various #ages & #genotypes w/ a focus on regulatory roles of #ImmuneSystem on #aging !
Reposted by James Thaventhiran
I’m finding the community here far more engaging and respectful, while still wickedly funny. Happy to be migrating to these friendlier skies.
November 22, 2024 at 4:27 AM
I’m finding the community here far more engaging and respectful, while still wickedly funny. Happy to be migrating to these friendlier skies.
Reposted by James Thaventhiran
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
docs.bsky.app
November 18, 2024 at 2:48 PM
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
Reposted by James Thaventhiran
The list is growing, amazing physician/scientists on here! please follow along
November 22, 2024 at 7:16 AM
The list is growing, amazing physician/scientists on here! please follow along
Reposted by James Thaventhiran
🚨 Delighted to share our paper defining a new role for IL-6 in TB. 🚨
We used genetic variation to show *reduced* IL-6 signalling is causally associated with *lower* risk of TB.
Lead author @gushamilton.bsky.social
#TBSky #IDSky #ImmunoSky www.thelancet.com/journals/lan...
Thread 👇 (1/8)
We used genetic variation to show *reduced* IL-6 signalling is causally associated with *lower* risk of TB.
Lead author @gushamilton.bsky.social
#TBSky #IDSky #ImmunoSky www.thelancet.com/journals/lan...
Thread 👇 (1/8)
Altered IL-6 signalling and risk of tuberculosis: a multi-ancestry mendelian randomisation study
Our findings propose a causal relationship between reduced IL-6 signalling and lower
risk of tuberculosis, akin to the effect seen in other IL-6 mediated diseases. This
study suggests that IL-6 antago...
www.thelancet.com
November 21, 2024 at 10:30 AM
🚨 Delighted to share our paper defining a new role for IL-6 in TB. 🚨
We used genetic variation to show *reduced* IL-6 signalling is causally associated with *lower* risk of TB.
Lead author @gushamilton.bsky.social
#TBSky #IDSky #ImmunoSky www.thelancet.com/journals/lan...
Thread 👇 (1/8)
We used genetic variation to show *reduced* IL-6 signalling is causally associated with *lower* risk of TB.
Lead author @gushamilton.bsky.social
#TBSky #IDSky #ImmunoSky www.thelancet.com/journals/lan...
Thread 👇 (1/8)
Maybe worm lovers are conservative and still all on twitter?
Right, I think its time to say: where are my wormy people at?! The Immunology community on here is doing well, but Parasitology seems much more sparse?
November 21, 2024 at 1:09 PM
Maybe worm lovers are conservative and still all on twitter?
At our Unit annual science day Members of my lab got prizes for equality diversity and inclusion, mentorship and here’s Vita with her certificate for Public Engagement!— ‘An experiment isn’t complete until the results are communicated!’
November 20, 2024 at 11:15 PM
At our Unit annual science day Members of my lab got prizes for equality diversity and inclusion, mentorship and here’s Vita with her certificate for Public Engagement!— ‘An experiment isn’t complete until the results are communicated!’
Please add me.
We’ve jumped on board fully here on 🦋
A starter pack of those working on our favourite cell … the T cell 🥰🙈🥰
If you want an add let us know
go.bsky.app/8B5P25c
A starter pack of those working on our favourite cell … the T cell 🥰🙈🥰
If you want an add let us know
go.bsky.app/8B5P25c
November 20, 2024 at 6:08 AM
Please add me.
Reposted by James Thaventhiran
Bluesky tip for newbies: Bluesky has no real algorithm. Likes here do nothing but show the poster that you enjoyed their content.
That kindness is always going to be appreciated by creators, but if you want to help to boost something here, you have to repost it so others see it. 🙂
That kindness is always going to be appreciated by creators, but if you want to help to boost something here, you have to repost it so others see it. 🙂
November 18, 2024 at 10:27 AM
Bluesky tip for newbies: Bluesky has no real algorithm. Likes here do nothing but show the poster that you enjoyed their content.
That kindness is always going to be appreciated by creators, but if you want to help to boost something here, you have to repost it so others see it. 🙂
That kindness is always going to be appreciated by creators, but if you want to help to boost something here, you have to repost it so others see it. 🙂
Reposted by James Thaventhiran
Check it out!!! Our work delineating why T cells aren't needed for Salmonella colorectal cancer therapy, and how to get them on board is out 😅🧪🦠. @cruk-si.bsky.social Collab with @bendinglab.bsky.social @sarahdimeloe.bsky.social #Immunosky #Microsky #metabolism www.embopress.org/doi/full/10....
www.embopress.org
November 18, 2024 at 12:59 PM
Check it out!!! Our work delineating why T cells aren't needed for Salmonella colorectal cancer therapy, and how to get them on board is out 😅🧪🦠. @cruk-si.bsky.social Collab with @bendinglab.bsky.social @sarahdimeloe.bsky.social #Immunosky #Microsky #metabolism www.embopress.org/doi/full/10....
Reposted by James Thaventhiran
Time is running out for you to book your place for the BSI
#ImmuneTherapies24 Summit 👉 bit.ly/4eYp306
This event will bring together #clinical, academic and
#industry thought leaders from across the #ImmuneTherapies field 🤩
🗓️ 25-26 November
#ImmuneTherapies24 Summit 👉 bit.ly/4eYp306
This event will bring together #clinical, academic and
#industry thought leaders from across the #ImmuneTherapies field 🤩
🗓️ 25-26 November
November 18, 2024 at 11:31 AM
Time is running out for you to book your place for the BSI
#ImmuneTherapies24 Summit 👉 bit.ly/4eYp306
This event will bring together #clinical, academic and
#industry thought leaders from across the #ImmuneTherapies field 🤩
🗓️ 25-26 November
#ImmuneTherapies24 Summit 👉 bit.ly/4eYp306
This event will bring together #clinical, academic and
#industry thought leaders from across the #ImmuneTherapies field 🤩
🗓️ 25-26 November
As a way of an introduction, this video provides a reasonable description of some of our recent research. www.youtube.com/watch?v=rCW3...
The paper can be accessed here: www.nature.com/articles/s41...
#ImmunoSky
The paper can be accessed here: www.nature.com/articles/s41...
#ImmunoSky
Did frame-shifting shift our safety assessment?
YouTube video by Debunk the Funk with Dr. Wilson
www.youtube.com
November 17, 2024 at 3:54 PM
As a way of an introduction, this video provides a reasonable description of some of our recent research. www.youtube.com/watch?v=rCW3...
The paper can be accessed here: www.nature.com/articles/s41...
#ImmunoSky
The paper can be accessed here: www.nature.com/articles/s41...
#ImmunoSky
Brilliant to see so many colleagues here already.
Wonderful to see the #immunology community growing here.
The first starter pack is full (they cap at 150), so I created a second one. Let me know if you'd like to be added
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
The first starter pack is full (they cap at 150), so I created a second one. Let me know if you'd like to be added
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
November 16, 2024 at 2:26 PM
Brilliant to see so many colleagues here already.
Reposted by James Thaventhiran
Tolerance by eviction
"we report that, in mice, CD8 T cell tolerance instead results from premature thymic eviction of immature autoreactive CD8 thymocytes into the periphery, where they differentiate into self-tolerant mature CD8 T cells"
#Immunology #Immunosky
"we report that, in mice, CD8 T cell tolerance instead results from premature thymic eviction of immature autoreactive CD8 thymocytes into the periphery, where they differentiate into self-tolerant mature CD8 T cells"
#Immunology #Immunosky
CD8 T cell tolerance results from eviction of immature autoreactive cells from the thymus
Thymic eviction explains CD8 T cell tolerance and why autoreactive CD8 T cells appear in the periphery but not the thymus.
www.science.org
November 15, 2024 at 10:44 PM
Tolerance by eviction
"we report that, in mice, CD8 T cell tolerance instead results from premature thymic eviction of immature autoreactive CD8 thymocytes into the periphery, where they differentiate into self-tolerant mature CD8 T cells"
#Immunology #Immunosky
"we report that, in mice, CD8 T cell tolerance instead results from premature thymic eviction of immature autoreactive CD8 thymocytes into the periphery, where they differentiate into self-tolerant mature CD8 T cells"
#Immunology #Immunosky
Really looking forward to this great meeting. Who else is going? www.immunology.org/events/bsi-i...
BSI Immune Therapies Summit | British Society for Immunology
www.immunology.org
November 14, 2024 at 8:57 PM
Really looking forward to this great meeting. Who else is going? www.immunology.org/events/bsi-i...