Telomerase_Scott Cohen
@telomerase-cmri.bsky.social
Telomerase research down under! (Children's Medical Research Institute, Westmead NSW Australia)
Reposted by Telomerase_Scott Cohen
Australians: we don't like guns. This is excellent.
December 22, 2025 at 8:43 PM
Australians: we don't like guns. This is excellent.
Reposted by Telomerase_Scott Cohen
Reposted by Telomerase_Scott Cohen
Oh to be a little Tardigrade walking across a microscopic slide. 🫧🐻🧪
December 16, 2025 at 7:00 PM
Oh to be a little Tardigrade walking across a microscopic slide. 🫧🐻🧪
Reposted by Telomerase_Scott Cohen
Here's our reporting on the proposed dismantling of the jewel of US atmospheric science, @ncar-ucar.bsky.social.
The plan is to break NCAR apart and disburse some parts to other locations (like the research aircraft fleet) and eliminate others.
www.nature.com/articles/d41...
🧪 #AGU25 #climate
The plan is to break NCAR apart and disburse some parts to other locations (like the research aircraft fleet) and eliminate others.
www.nature.com/articles/d41...
🧪 #AGU25 #climate
Trump team plans to break up ‘global mothership’ of climate science
Much of the National Center for Atmospheric Research’s non-climate portfolio will be dispersed, the White House says.
www.nature.com
December 17, 2025 at 6:59 PM
Here's our reporting on the proposed dismantling of the jewel of US atmospheric science, @ncar-ucar.bsky.social.
The plan is to break NCAR apart and disburse some parts to other locations (like the research aircraft fleet) and eliminate others.
www.nature.com/articles/d41...
🧪 #AGU25 #climate
The plan is to break NCAR apart and disburse some parts to other locations (like the research aircraft fleet) and eliminate others.
www.nature.com/articles/d41...
🧪 #AGU25 #climate
Reposted by Telomerase_Scott Cohen
Trump Announces 5,000% Increase In All Numbers
Trump Announces 5,000% Increase In All Numbers
WASHINGTON—Touting his latest executive order as a historic win for the U.S. economy, President Donald Trump announced Friday that he was mandating a 5,000% increase in all numbers nationwide. “Effect...
theonion.com
December 18, 2025 at 2:22 AM
Trump Announces 5,000% Increase In All Numbers
Reposted by Telomerase_Scott Cohen
We are grateful to the National Health and Medical Research Council for granting four of our scientists highly sought after Ideas Grants. https://www.cmrijeansforgenes.org.au/news/cmri-researchers-awarded-four-nhmrc-grants
Tony Cesare
Tony Cesare
December 18, 2025 at 5:38 AM
We are grateful to the National Health and Medical Research Council for granting four of our scientists highly sought after Ideas Grants. https://www.cmrijeansforgenes.org.au/news/cmri-researchers-awarded-four-nhmrc-grants
Tony Cesare
Tony Cesare
Reposted by Telomerase_Scott Cohen
3/ I’m relieved to have secured funding to sustain my lab, but am deeply concerned about the long-term health of Australia’s research sector. Our grant structures and peer review systems are in urgent need of reform.
December 18, 2025 at 6:45 AM
3/ I’m relieved to have secured funding to sustain my lab, but am deeply concerned about the long-term health of Australia’s research sector. Our grant structures and peer review systems are in urgent need of reform.
Reposted by Telomerase_Scott Cohen
If I may be allowed a moment of fatherly pride.
Huge congratulations to Maddy Cesare on being selected for the New South Wales team competing at the Australian Youth Women’s Baseball Championship ⚾️🇦🇺
A big achievement, especially in her first year of eligibility.
Baseball is awesome.
Huge congratulations to Maddy Cesare on being selected for the New South Wales team competing at the Australian Youth Women’s Baseball Championship ⚾️🇦🇺
A big achievement, especially in her first year of eligibility.
Baseball is awesome.
December 18, 2025 at 10:33 AM
If I may be allowed a moment of fatherly pride.
Huge congratulations to Maddy Cesare on being selected for the New South Wales team competing at the Australian Youth Women’s Baseball Championship ⚾️🇦🇺
A big achievement, especially in her first year of eligibility.
Baseball is awesome.
Huge congratulations to Maddy Cesare on being selected for the New South Wales team competing at the Australian Youth Women’s Baseball Championship ⚾️🇦🇺
A big achievement, especially in her first year of eligibility.
Baseball is awesome.
Reposted by Telomerase_Scott Cohen
Letter from Congress to FDA re: undermining vaccines, page 1 of 6
December 7, 2025 at 4:12 PM
Letter from Congress to FDA re: undermining vaccines, page 1 of 6
Reposted by Telomerase_Scott Cohen
Reposted by Telomerase_Scott Cohen
New @natcomms.nature.com paper today from Tracy Bryan's lab @cmri.bsky.social: "Nuclear actin and DNA replication stress regulate telomere maintenance by telomerase".
Happy our lab could play a small part.
Congrats Tracy, Ash Harman, Noa Lamm and the whole team.
www.nature.com/articles/s41...
Happy our lab could play a small part.
Congrats Tracy, Ash Harman, Noa Lamm and the whole team.
www.nature.com/articles/s41...
Nuclear actin and DNA replication stress regulate telomere maintenance by telomerase - Nature Communications
Telomerase recruitment to telomeres is a tightly regulated process which is stimulated by replication stress. Here, the authors identify that nuclear filamentous actin is important for interaction bet...
www.nature.com
December 3, 2025 at 12:19 AM
New @natcomms.nature.com paper today from Tracy Bryan's lab @cmri.bsky.social: "Nuclear actin and DNA replication stress regulate telomere maintenance by telomerase".
Happy our lab could play a small part.
Congrats Tracy, Ash Harman, Noa Lamm and the whole team.
www.nature.com/articles/s41...
Happy our lab could play a small part.
Congrats Tracy, Ash Harman, Noa Lamm and the whole team.
www.nature.com/articles/s41...
Reposted by Telomerase_Scott Cohen
December 4, 2025 at 4:32 PM
Reposted by Telomerase_Scott Cohen
Science’s 2024 Breakthrough of the Year was lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months.
Learn more about last year's #BOTY on #WorldAIDSDay: https://scim.ag/48pk7zZ
Learn more about last year's #BOTY on #WorldAIDSDay: https://scim.ag/48pk7zZ
December 1, 2025 at 7:04 PM
Science’s 2024 Breakthrough of the Year was lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months.
Learn more about last year's #BOTY on #WorldAIDSDay: https://scim.ag/48pk7zZ
Learn more about last year's #BOTY on #WorldAIDSDay: https://scim.ag/48pk7zZ
Reposted by Telomerase_Scott Cohen
The success rate for NHMRC Ideas Grants announced yesterday was just over 8%. That means 11 of every 12 people who applied got rejected. This is a culture changing level of rejection and frankly a point of national shame. This is a crisis for research.
I will not rest until we see this resolved.
I will not rest until we see this resolved.
November 26, 2025 at 8:34 PM
The success rate for NHMRC Ideas Grants announced yesterday was just over 8%. That means 11 of every 12 people who applied got rejected. This is a culture changing level of rejection and frankly a point of national shame. This is a crisis for research.
I will not rest until we see this resolved.
I will not rest until we see this resolved.
Reposted by Telomerase_Scott Cohen
Thankful for breakthroughs!
t.co/Khbj4npOP1
t.co/Khbj4npOP1
November 27, 2025 at 4:35 PM
Thankful for breakthroughs!
t.co/Khbj4npOP1
t.co/Khbj4npOP1
Reposted by Telomerase_Scott Cohen
Thank you @cmri.bsky.social for the nomination; @sydney.edu.au for this recognition; and our team for making this research possible.
November 27, 2025 at 5:41 AM
Thank you @cmri.bsky.social for the nomination; @sydney.edu.au for this recognition; and our team for making this research possible.
Reposted by Telomerase_Scott Cohen
A Moon Halo So Perfect
Last night over New York, a flawless 22° ice-crystal halo formed around the full Moon — a radiant circle shining above the Statue of Liberty.
Last night over New York, a flawless 22° ice-crystal halo formed around the full Moon — a radiant circle shining above the Statue of Liberty.
November 25, 2025 at 8:12 AM
A Moon Halo So Perfect
Last night over New York, a flawless 22° ice-crystal halo formed around the full Moon — a radiant circle shining above the Statue of Liberty.
Last night over New York, a flawless 22° ice-crystal halo formed around the full Moon — a radiant circle shining above the Statue of Liberty.
Reposted by Telomerase_Scott Cohen
Neoliberalism's toll: "a weakened public school system, financially stressed universities, and a #CSIRO repeatedly stripped of long-term capability."
We have lost "depth, continuity, and trust, conditions that science requires but markets cannot provide." #auspol
johnmenadue.com/post/2025/11...
We have lost "depth, continuity, and trust, conditions that science requires but markets cannot provide." #auspol
johnmenadue.com/post/2025/11...
Innovation talk, austerity walk: Australia’s failing science policy
Despite constant rhetoric about innovation, Australia is steadily dismantling its scientific capacity. Public schools, universities and the CSIRO are all under pressure – the result of decades of mark...
johnmenadue.com
November 23, 2025 at 8:01 PM
Neoliberalism's toll: "a weakened public school system, financially stressed universities, and a #CSIRO repeatedly stripped of long-term capability."
We have lost "depth, continuity, and trust, conditions that science requires but markets cannot provide." #auspol
johnmenadue.com/post/2025/11...
We have lost "depth, continuity, and trust, conditions that science requires but markets cannot provide." #auspol
johnmenadue.com/post/2025/11...
Reposted by Telomerase_Scott Cohen
Australia’s algal bloom catastrophe has left more than 87,000 animals dead. What will happen this summer?
Six researchers in this space, including myself, have lost their positions at Flinders University in a restructure. theconversation.com/australias-a...
Six researchers in this space, including myself, have lost their positions at Flinders University in a restructure. theconversation.com/australias-a...
Australia’s algal bloom catastrophe has left more than 87,000 animals dead. What will happen this summer?
It’s one of Australia’s worst underwater environmental catastrophes. What’s going to happen to South Australia’s vast algal bloom as summer heat warms the ocean?
theconversation.com
November 20, 2025 at 11:29 AM
Australia’s algal bloom catastrophe has left more than 87,000 animals dead. What will happen this summer?
Six researchers in this space, including myself, have lost their positions at Flinders University in a restructure. theconversation.com/australias-a...
Six researchers in this space, including myself, have lost their positions at Flinders University in a restructure. theconversation.com/australias-a...
Reposted by Telomerase_Scott Cohen
This is why for a long time I've found the Prime Minister's Prizes for Science a rather insulting propaganda exercise
www.abc.net.au/news/science...
CSIRO funding as a percentage of GDP:
1982-83 = 0.17
2024-25 = 0.03
...
Scientific extinction event imminent?
www.abc.net.au/news/science...
CSIRO funding as a percentage of GDP:
1982-83 = 0.17
2024-25 = 0.03
...
Scientific extinction event imminent?
The CSIRO cuts are just the tip of the iceberg for Australia's science funding
Australia is known as a country of innovators, but with a combination of brain drain, continuous cuts, and a loss of critical science projects, is Australia losing its edge?
www.abc.net.au
November 19, 2025 at 7:01 AM
This is why for a long time I've found the Prime Minister's Prizes for Science a rather insulting propaganda exercise
www.abc.net.au/news/science...
CSIRO funding as a percentage of GDP:
1982-83 = 0.17
2024-25 = 0.03
...
Scientific extinction event imminent?
www.abc.net.au/news/science...
CSIRO funding as a percentage of GDP:
1982-83 = 0.17
2024-25 = 0.03
...
Scientific extinction event imminent?
Reposted by Telomerase_Scott Cohen
Over the last century, research has helped improve the early detection and treatment of serious diseases. But future progress is at risk unless we continue federal funding for medical research.
#AmericansForMedicalResearch
#AmericansForMedicalResearch
November 20, 2025 at 4:26 AM
Over the last century, research has helped improve the early detection and treatment of serious diseases. But future progress is at risk unless we continue federal funding for medical research.
#AmericansForMedicalResearch
#AmericansForMedicalResearch
Reposted by Telomerase_Scott Cohen
“CSIRO has announced it will slash up to 350 jobs as the national science agency grapples with long-term financial challenges … with current funding failing to keep pace with the rising costs of running a modern science agency.”
Not “challenges”. They’re choices. 😡
Not “challenges”. They’re choices. 😡
CSIRO to cut up to 350 research jobs in major overhaul
After 440 positions were slashed last year, the CSIRO has announced more staff cuts across the country in a bid to remain financially viable.
www.abc.net.au
November 18, 2025 at 6:15 AM
“CSIRO has announced it will slash up to 350 jobs as the national science agency grapples with long-term financial challenges … with current funding failing to keep pace with the rising costs of running a modern science agency.”
Not “challenges”. They’re choices. 😡
Not “challenges”. They’re choices. 😡
Reposted by Telomerase_Scott Cohen
My latest for @science.org: A remarkable set of high-resolution climate model runs, computed over 900 (!) days of supercomputing time, are revealing how warming-induced changes to Earth's wind patterns due can prime huge spikes in extreme rainfall.
But the MESACLIP runs also do much more than that.
But the MESACLIP runs also do much more than that.
High-resolution climate model forecasts a wet, turbulent future
With details as fine as short-term weather forecasts, model achieves newfound accuracy
www.science.org
November 18, 2025 at 2:35 PM
My latest for @science.org: A remarkable set of high-resolution climate model runs, computed over 900 (!) days of supercomputing time, are revealing how warming-induced changes to Earth's wind patterns due can prime huge spikes in extreme rainfall.
But the MESACLIP runs also do much more than that.
But the MESACLIP runs also do much more than that.
Reposted by Telomerase_Scott Cohen
My quote of the day
In a world where everyone is behaving honestly, any dishonesty constitutes a big infraction. But, in a world where many people are behaving dishonestly, and the news is filled with stories of their infractions, even big infractions can feel small to the perpetrator.
Dan Ariely
In a world where everyone is behaving honestly, any dishonesty constitutes a big infraction. But, in a world where many people are behaving dishonestly, and the news is filled with stories of their infractions, even big infractions can feel small to the perpetrator.
Dan Ariely
November 16, 2025 at 1:32 PM
My quote of the day
In a world where everyone is behaving honestly, any dishonesty constitutes a big infraction. But, in a world where many people are behaving dishonestly, and the news is filled with stories of their infractions, even big infractions can feel small to the perpetrator.
Dan Ariely
In a world where everyone is behaving honestly, any dishonesty constitutes a big infraction. But, in a world where many people are behaving dishonestly, and the news is filled with stories of their infractions, even big infractions can feel small to the perpetrator.
Dan Ariely
Reposted by Telomerase_Scott Cohen
Finally! We have a FANCM:RMI inhibitor that is cell active and specifically kills ALT+ cancer cells 🎯
@yuhenglau.bsky.social + my labs just published the first cell-active peptide inhibitors of this critical target in 10-15% of cancers. doi.org/10.1021/acs....
@yuhenglau.bsky.social + my labs just published the first cell-active peptide inhibitors of this critical target in 10-15% of cancers. doi.org/10.1021/acs....
November 17, 2025 at 5:24 AM
Finally! We have a FANCM:RMI inhibitor that is cell active and specifically kills ALT+ cancer cells 🎯
@yuhenglau.bsky.social + my labs just published the first cell-active peptide inhibitors of this critical target in 10-15% of cancers. doi.org/10.1021/acs....
@yuhenglau.bsky.social + my labs just published the first cell-active peptide inhibitors of this critical target in 10-15% of cancers. doi.org/10.1021/acs....