Suzana Salcedo
@suzanasalcedo.bsky.social
Passionate about bacteria and host cell responses to infection. 🇵🇹&🇺🇸 and a bit 🇫🇷 Associate Professor, University of Wisconsin-Madison. Opinions my own.
Reposted by Suzana Salcedo
Our latest T7SS study is now out in Science Advances!
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
A ubiquitin-like protein controls assembly of a bacterial type VIIb secretion system
Cryo-EM structure reveals how a ubiquitin-like protein orchestrates assembly of a bacterial weapon system.
www.science.org
November 21, 2025 at 7:05 PM
Our latest T7SS study is now out in Science Advances!
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
Reposted by Suzana Salcedo
Reposted by Suzana Salcedo
Happy to share our latest T6SS review:
nature.com/articles/s41...
Thank you, Jan, Danny (@dannyjamesward.bsky.social), Joana (@joanampereira.bsky.social), as well as reviewers and editors @natrevmicro.nature.com!
nature.com/articles/s41...
Thank you, Jan, Danny (@dannyjamesward.bsky.social), Joana (@joanampereira.bsky.social), as well as reviewers and editors @natrevmicro.nature.com!
The type VI secretion system and associated effector proteins - Nature Reviews Microbiology
In this Review, Basler and colleagues examine the type VI secretion system (T6SS), focusing on the diversity of antibacterial T6SS effectors and the evolutionary forces that shape them. They explain h...
nature.com
November 17, 2025 at 10:08 AM
Happy to share our latest T6SS review:
nature.com/articles/s41...
Thank you, Jan, Danny (@dannyjamesward.bsky.social), Joana (@joanampereira.bsky.social), as well as reviewers and editors @natrevmicro.nature.com!
nature.com/articles/s41...
Thank you, Jan, Danny (@dannyjamesward.bsky.social), Joana (@joanampereira.bsky.social), as well as reviewers and editors @natrevmicro.nature.com!
Reposted by Suzana Salcedo
Happy to share our latest NAR paper on Rel toxins targeting M. tuberculosis anti-SD region, with Tim Blower’s team (@durham.ac.uk @nebiolabs.bsky.social) and Laurent Falquet
Thanks to FRM @frm-officiel.bsky.social and CNRS @cnrsbiologie.bsky.social
academic.oup.com/nar/article-...
Thanks to FRM @frm-officiel.bsky.social and CNRS @cnrsbiologie.bsky.social
academic.oup.com/nar/article-...
November 17, 2025 at 10:31 AM
Happy to share our latest NAR paper on Rel toxins targeting M. tuberculosis anti-SD region, with Tim Blower’s team (@durham.ac.uk @nebiolabs.bsky.social) and Laurent Falquet
Thanks to FRM @frm-officiel.bsky.social and CNRS @cnrsbiologie.bsky.social
academic.oup.com/nar/article-...
Thanks to FRM @frm-officiel.bsky.social and CNRS @cnrsbiologie.bsky.social
academic.oup.com/nar/article-...
Reposted by Suzana Salcedo
Who wants to discuss innate immunity and host defense?
Join us in Banff to share your exciting research.
www.keystonesymposia.org/conferences/...
Join us in Banff to share your exciting research.
www.keystonesymposia.org/conferences/...
Innate Immunity: Diversity in Host Defense and Disease | Keystone Symposia
Join us at the Keystone Symposia on Innate Immunity: Diversity in Host Defense and Disease, March 2026, in Banff, with field leaders!
www.keystonesymposia.org
November 11, 2025 at 2:55 PM
Who wants to discuss innate immunity and host defense?
Join us in Banff to share your exciting research.
www.keystonesymposia.org/conferences/...
Join us in Banff to share your exciting research.
www.keystonesymposia.org/conferences/...
Reposted by Suzana Salcedo
For anyone interested in doing a PhD at the interface of microbiology and immunology focusing on how AMR pathogens subvert host defenses...you may consider applying to our MRC LID DTP project in which we will explore how Klebsiella hijacks the immune checkpoint PD-L1 mrc-lid.lshtm.ac.uk/apply/
How to Apply - MRC London Intercollegiate Doctoral Training Partnership Studentships
MRC LID is open for application for 2026-27 PRE-APPLICATION STEPS 1. Find out more about...
mrc-lid.lshtm.ac.uk
November 10, 2025 at 8:48 AM
For anyone interested in doing a PhD at the interface of microbiology and immunology focusing on how AMR pathogens subvert host defenses...you may consider applying to our MRC LID DTP project in which we will explore how Klebsiella hijacks the immune checkpoint PD-L1 mrc-lid.lshtm.ac.uk/apply/
Reposted by Suzana Salcedo
🎉 Big congratulations to Dr. Andrew Hryckowian on receiving the Vilas Faculty Early-Career Investigator Award! His groundbreaking work on the gut microbiome is shaping the future of infectious disease research.
mmi.wisc.edu/dr-andrew-hr...
mmi.wisc.edu/dr-andrew-hr...
November 7, 2025 at 3:36 PM
🎉 Big congratulations to Dr. Andrew Hryckowian on receiving the Vilas Faculty Early-Career Investigator Award! His groundbreaking work on the gut microbiome is shaping the future of infectious disease research.
mmi.wisc.edu/dr-andrew-hr...
mmi.wisc.edu/dr-andrew-hr...
Reposted by Suzana Salcedo
Let's go! Super excited to partner with @richardsever.bsky.social and the fantastic @openrxiv.bsky.social team - Preprints have been the best thing that happened to science publishing during my lifetime, and we're happy @qedscience.bsky.social can make preprints do more 👊
November 6, 2025 at 2:52 PM
Let's go! Super excited to partner with @richardsever.bsky.social and the fantastic @openrxiv.bsky.social team - Preprints have been the best thing that happened to science publishing during my lifetime, and we're happy @qedscience.bsky.social can make preprints do more 👊
Reposted by Suzana Salcedo
Many antiphage systems use NAD+, in many ways.
@hugovaysset.bsky.social reviewed them all!
Read to know more about all their molecular mechanisms, how phages counteract them, their distribution in bacteria and their conservation in eukaryotic immunity!
www.cell.com/molecular-ce...
@hugovaysset.bsky.social reviewed them all!
Read to know more about all their molecular mechanisms, how phages counteract them, their distribution in bacteria and their conservation in eukaryotic immunity!
www.cell.com/molecular-ce...
The multifaceted roles of NAD+ in bacterial immunity
In this review, Vaysset and Bernheim examine how nicotinamide adenine dinucleotide
(NAD+) is a key player in diverse and widespread bacterial antiphage defense systems
and phage counterdefense. The au...
www.cell.com
October 17, 2025 at 5:55 PM
Many antiphage systems use NAD+, in many ways.
@hugovaysset.bsky.social reviewed them all!
Read to know more about all their molecular mechanisms, how phages counteract them, their distribution in bacteria and their conservation in eukaryotic immunity!
www.cell.com/molecular-ce...
@hugovaysset.bsky.social reviewed them all!
Read to know more about all their molecular mechanisms, how phages counteract them, their distribution in bacteria and their conservation in eukaryotic immunity!
www.cell.com/molecular-ce...
Reposted by Suzana Salcedo
I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...
beta.ideas.lego.com/product-idea...
Biological Laboratory | LEGO® Ideas
This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ…
beta.ideas.lego.com
October 16, 2025 at 8:07 AM
I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...
beta.ideas.lego.com/product-idea...
Reposted by Suzana Salcedo
🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for genetic code expansion - Nature
Bacterial ATP-binding cassette (ABC) transporters can be utilized and engineered to transport non-canonical amino acids into Escherichia coli for highly efficient synthesis of proteins with novel func...
www.nature.com
October 16, 2025 at 2:06 PM
🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Reposted by Suzana Salcedo
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
October 15, 2025 at 6:32 PM
Reposted by Suzana Salcedo
Predatory practices plague modern science, but the origins & reasons of their success can be identified—and solutions exist. Instead of blacklists, funding agencies should foster accreditation systems. See analyses & proposals of the EAM Task Force of @femsmicro.org on the matter shorturl.at/gVXJR
October 12, 2025 at 8:27 AM
Predatory practices plague modern science, but the origins & reasons of their success can be identified—and solutions exist. Instead of blacklists, funding agencies should foster accreditation systems. See analyses & proposals of the EAM Task Force of @femsmicro.org on the matter shorturl.at/gVXJR
Reposted by Suzana Salcedo
A new underwater microscope designed & built by Scripps is providing an unprecedented glimpse into the hidden world of corals. 🪸🔬 @californiacurated.bsky.social shares how this imaging system is revealing new insights that could help save #CoralReefs. californiacurated.substack.com/p/a-microsco...
Corals Revealed as Never Before Through a Groundbreaking New Microscope in California
A new imaging system developed at Scripps allows researchers to see coral polyps and their algae symbionts like never before, offering insights that could help save reefs before they vanish.
californiacurated.substack.com
October 10, 2025 at 5:01 PM
A new underwater microscope designed & built by Scripps is providing an unprecedented glimpse into the hidden world of corals. 🪸🔬 @californiacurated.bsky.social shares how this imaging system is revealing new insights that could help save #CoralReefs. californiacurated.substack.com/p/a-microsco...
Reposted by Suzana Salcedo
Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here:
emploi.cnrs.fr/Offres/Docto...
emploi.cnrs.fr/Offres/Docto...
Portail Emploi CNRS - Offre d'emploi - Thèse en Microbiologie-Biochimie (H/F)
emploi.cnrs.fr
October 9, 2025 at 12:18 PM
Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here:
emploi.cnrs.fr/Offres/Docto...
emploi.cnrs.fr/Offres/Docto...
Reposted by Suzana Salcedo
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply here apply.interfolio.com/174404
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 5, 2025 at 12:03 PM
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply here apply.interfolio.com/174404
Reposted by Suzana Salcedo
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
October 4, 2025 at 6:46 PM
Reposted by Suzana Salcedo
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Independent Research Fellowships Leading to Tenured Faculty Positions | John Innes Centre
The John Innes Centre (JIC), is a world leading centre of excellence in plant and microbial sciences based on the Norwich Research Park, UK. We are inviting applications from outstanding researchers…
www.jic.ac.uk
October 3, 2025 at 4:06 PM
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Reposted by Suzana Salcedo
I'm thrilled to announce I'll be joining the Department of Molecular Genetics & Microbiology at the University of Florida in January 2026! My lab will study RNA virus-host interactions with a particular focus on the spatial regulation of viral replication and innate immune activation. genoyerlab.com
Genoyer Lab
genoyerlab.com
October 3, 2025 at 6:10 PM
I'm thrilled to announce I'll be joining the Department of Molecular Genetics & Microbiology at the University of Florida in January 2026! My lab will study RNA virus-host interactions with a particular focus on the spatial regulation of viral replication and innate immune activation. genoyerlab.com
Reposted by Suzana Salcedo
On the way to Midwest Microbial Pathogenesis Conference 2025, in St Charles, Illinois!
Hosted by Loyola University Chicago
#MMPC2025
#MicroSky
www.mmpconference2025.com
Hosted by Loyola University Chicago
#MMPC2025
#MicroSky
www.mmpconference2025.com
October 3, 2025 at 4:01 PM
On the way to Midwest Microbial Pathogenesis Conference 2025, in St Charles, Illinois!
Hosted by Loyola University Chicago
#MMPC2025
#MicroSky
www.mmpconference2025.com
Hosted by Loyola University Chicago
#MMPC2025
#MicroSky
www.mmpconference2025.com
Reposted by Suzana Salcedo
Our new preprint by @nanamikubota.bsky.social shows that P. aeruginosa, and likely many other bacteria carrying filamentous prophages (like V. parahaemolyticus), risk being exploited by these phages in a runaway process that reduces fitness of both host and virus. www.biorxiv.org/content/10.1... 🧵
Filamentous cheater phages drive bacterial and phage populations to lower fitness
Many bacteria carry phage genome(s) in their chromosome (i.e., prophage), and this intertwines the fitness of the bacterium and the phage. Most Pseudomonas aeruginosa strains carry filamentous phages ...
www.biorxiv.org
April 3, 2025 at 5:06 PM
Our new preprint by @nanamikubota.bsky.social shows that P. aeruginosa, and likely many other bacteria carrying filamentous prophages (like V. parahaemolyticus), risk being exploited by these phages in a runaway process that reduces fitness of both host and virus. www.biorxiv.org/content/10.1... 🧵
Reposted by Suzana Salcedo
Acinetobacter exhibits cyrcadian rhythms! These bugs can predict the light cycles and adjust the expression of genes accordingy. Amazing collaboration with Alejandra Mussi's team from Rosario, Argentina, my city!!
rdcu.be/eIQzL
rdcu.be/eIQzL
The critical human pathogen Acinetobacter baumannii exhibits light-regulated circadian rhythms
Communications Biology - Gene expression studies in the critical pathogen Acinetobacter baumannii identified the existence of daily rhythms displaying a robust response to light, as well as...
rdcu.be
September 30, 2025 at 4:54 PM
Acinetobacter exhibits cyrcadian rhythms! These bugs can predict the light cycles and adjust the expression of genes accordingy. Amazing collaboration with Alejandra Mussi's team from Rosario, Argentina, my city!!
rdcu.be/eIQzL
rdcu.be/eIQzL
Reposted by Suzana Salcedo
I said I will never work on phages, but having @micheleleroux.bsky.social next door made me change my mind. Here is Alexis's new paper showing how different phages deal with the capsular barrier to infect Acinetobacter! A great collaboration between our labs!
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Acinetobacter phages use distinct strategies to breach the capsule barrier
Author summary Acinetobacter baumannii causes life-threatening and often antibiotic-resistant infections thereby posing a global threat. Accordingly, there is an urgent need for alternative treatments...
journals.plos.org
September 29, 2025 at 7:56 PM
I said I will never work on phages, but having @micheleleroux.bsky.social next door made me change my mind. Here is Alexis's new paper showing how different phages deal with the capsular barrier to infect Acinetobacter! A great collaboration between our labs!
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Reposted by Suzana Salcedo
Highly multiplexed 3D profiling of cell states and immune niches in human tumors @natmethods.nature.com @harvardmed.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
September 29, 2025 at 8:31 PM
Highly multiplexed 3D profiling of cell states and immune niches in human tumors @natmethods.nature.com @harvardmed.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Suzana Salcedo
View from the lab now. Did I mention that we are recruiting faculty microbiologists?
www.linkedin.com/posts/vaughn...
www.linkedin.com/posts/vaughn...
September 29, 2025 at 2:43 PM
View from the lab now. Did I mention that we are recruiting faculty microbiologists?
www.linkedin.com/posts/vaughn...
www.linkedin.com/posts/vaughn...