Sébastien Poulin
@sebpoule.bsky.social
Medical microbiologist & Infectious diseases MD
@ St-Jérôme & Montréal, Québec, 🇨🇦
🔝 Interests HBV HDV HIV & General I.D.
French 🇨🇦 with a 💩 accent
#IDsky #HIVsky #Medsky
@ St-Jérôme & Montréal, Québec, 🇨🇦
🔝 Interests HBV HDV HIV & General I.D.
French 🇨🇦 with a 💩 accent
#IDsky #HIVsky #Medsky
Reposted by Sébastien Poulin
Can we really be grateful for anything in the ID world in 2025?
Sure -- plenty of great advances!
Here are a half-dozen to celebrate (and be grateful for) in 2025, believe it or not. #idsky
blogs.jwatch.org/hiv-id-obser...
Sure -- plenty of great advances!
Here are a half-dozen to celebrate (and be grateful for) in 2025, believe it or not. #idsky
blogs.jwatch.org/hiv-id-obser...
ID Things to Be Grateful for -- 2025 Edition
Looking back on these annual Thanksgiving posts, I notice an odd pattern: every few years, the intro turns into a kind of apology. As in, Yes, I know the title sounds upbeat, please don’t attack me. T...
blogs.jwatch.org
November 25, 2025 at 2:29 AM
Can we really be grateful for anything in the ID world in 2025?
Sure -- plenty of great advances!
Here are a half-dozen to celebrate (and be grateful for) in 2025, believe it or not. #idsky
blogs.jwatch.org/hiv-id-obser...
Sure -- plenty of great advances!
Here are a half-dozen to celebrate (and be grateful for) in 2025, believe it or not. #idsky
blogs.jwatch.org/hiv-id-obser...
Reposted by Sébastien Poulin
Inspired by this rage-inducing ad, I offer 3 big misses on antibiotics that need to die.
paulsaxmd.substack.com/p/three-myth...
paulsaxmd.substack.com/p/three-myth...
Three Myths About Antibiotics We Really Need to Retire
Sneezes, penicillin allergies, and those strangely sacred 5- and 7-day courses.
paulsaxmd.substack.com
November 21, 2025 at 3:53 PM
Inspired by this rage-inducing ad, I offer 3 big misses on antibiotics that need to die.
paulsaxmd.substack.com/p/three-myth...
paulsaxmd.substack.com/p/three-myth...
Fascinating CID Brief Report
➡️Safe implementation of novel HBV-inactive cART for people living with HIV and prior HBV exposure is of paramount importance and better clinical trial and real-world data is essential to inform best practice
➡️Safe implementation of novel HBV-inactive cART for people living with HIV and prior HBV exposure is of paramount importance and better clinical trial and real-world data is essential to inform best practice
Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice
✅ Just Accepted
🔗 https://bit.ly/4pmCEDJ
✅ Just Accepted
🔗 https://bit.ly/4pmCEDJ
November 23, 2025 at 7:06 PM
Fascinating CID Brief Report
➡️Safe implementation of novel HBV-inactive cART for people living with HIV and prior HBV exposure is of paramount importance and better clinical trial and real-world data is essential to inform best practice
➡️Safe implementation of novel HBV-inactive cART for people living with HIV and prior HBV exposure is of paramount importance and better clinical trial and real-world data is essential to inform best practice
Fascinating CID Brief Report #HIVsky #IDsky
« Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice»
(Thank you @josephmarcusid.medsky.social for flagging it)
academic.oup.com/cid/article/...
« Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice»
(Thank you @josephmarcusid.medsky.social for flagging it)
academic.oup.com/cid/article/...
Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice
Abstract. The potential for hepatitis B reactivation must be considered when switching people with HIV and prior hepatitis B exposure away from tenofovir-c
academic.oup.com
November 23, 2025 at 1:40 AM
Fascinating CID Brief Report #HIVsky #IDsky
« Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice»
(Thank you @josephmarcusid.medsky.social for flagging it)
academic.oup.com/cid/article/...
« Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice»
(Thank you @josephmarcusid.medsky.social for flagging it)
academic.oup.com/cid/article/...
Reposted by Sébastien Poulin
A great @cidjournal.bsky.social case series that led to lots of discussion with the fellows today- 4 🇬🇧 pts with HBV reactivation after change off of a TAF-based HIV regimen
Pt1/4: +HBcAB, -HBVsAg, -HBVsAB
Pt2/3: +HBcAB, -HBVsAg,+HBVsAB
#IDSky
academic.oup.com/cid/advance-...
Pt1/4: +HBcAB, -HBVsAg, -HBVsAB
Pt2/3: +HBcAB, -HBVsAg,+HBVsAB
#IDSky
academic.oup.com/cid/advance-...
Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice
Abstract. The potential for hepatitis B reactivation must be considered when switching people with HIV and prior hepatitis B exposure away from tenofovir-c
academic.oup.com
November 22, 2025 at 12:44 AM
A great @cidjournal.bsky.social case series that led to lots of discussion with the fellows today- 4 🇬🇧 pts with HBV reactivation after change off of a TAF-based HIV regimen
Pt1/4: +HBcAB, -HBVsAg, -HBVsAB
Pt2/3: +HBcAB, -HBVsAg,+HBVsAB
#IDSky
academic.oup.com/cid/advance-...
Pt1/4: +HBcAB, -HBVsAg, -HBVsAB
Pt2/3: +HBcAB, -HBVsAg,+HBVsAB
#IDSky
academic.oup.com/cid/advance-...
Reposted by Sébastien Poulin
🆕🔥🦴 Our 2025 Update to @wiki-guidelines.bsky.social for the Management of Pyogenic Osteomyelitis in Adults 🌟 @bradspellberg.bsky.social
🔗 [link] #idsky
www.amjmed.com/article/S000...
🔗 [link] #idsky
www.amjmed.com/article/S000...
November 19, 2025 at 4:25 PM
🆕🔥🦴 Our 2025 Update to @wiki-guidelines.bsky.social for the Management of Pyogenic Osteomyelitis in Adults 🌟 @bradspellberg.bsky.social
🔗 [link] #idsky
www.amjmed.com/article/S000...
🔗 [link] #idsky
www.amjmed.com/article/S000...
Le président du CMDP, Michel L’Allier;« On travaille beaucoup avec des cancers, et nous, qu’est-ce qu’on fait quand il y a un cancer ? On l’enlève. Quand une loi n’est pas bonne et que c’est un cancer pour le système de santé, on l’enlève »
#Loi2 = ⚠️ et 💩
www.lapresse.ca/actualites/s...
#Loi2 = ⚠️ et 💩
www.lapresse.ca/actualites/s...
Loi sur la rémunération des médecins | Les pédiatres de plusieurs hôpitaux manifestent
Des manifestations se sont déroulées dimanche aux quatre centres hospitaliers universitaires de pédiatrie de la province, en opposition au projet de loi 2, qui vise entre autres à lier la rémunération...
www.lapresse.ca
November 16, 2025 at 11:19 PM
Le président du CMDP, Michel L’Allier;« On travaille beaucoup avec des cancers, et nous, qu’est-ce qu’on fait quand il y a un cancer ? On l’enlève. Quand une loi n’est pas bonne et que c’est un cancer pour le système de santé, on l’enlève »
#Loi2 = ⚠️ et 💩
www.lapresse.ca/actualites/s...
#Loi2 = ⚠️ et 💩
www.lapresse.ca/actualites/s...
Je suis un médecin.
Je ne quitterai pas le Québec.
Je serai « ailleurs » dans ma tête.
Tout simplement.
Strict minimum.
Zéro motivation.
#JeMeSouviens #Loi2
Je ne quitterai pas le Québec.
Je serai « ailleurs » dans ma tête.
Tout simplement.
Strict minimum.
Zéro motivation.
#JeMeSouviens #Loi2
November 14, 2025 at 11:43 AM
Je suis un médecin.
Je ne quitterai pas le Québec.
Je serai « ailleurs » dans ma tête.
Tout simplement.
Strict minimum.
Zéro motivation.
#JeMeSouviens #Loi2
Je ne quitterai pas le Québec.
Je serai « ailleurs » dans ma tête.
Tout simplement.
Strict minimum.
Zéro motivation.
#JeMeSouviens #Loi2
Reposted by Sébastien Poulin
Anal cancer screening: a balanced approach is necessary
✅ Just Accepted
#IDTwitter
🔗 https://bit.ly/4oK9kra
✅ Just Accepted
#IDTwitter
🔗 https://bit.ly/4oK9kra
November 12, 2025 at 5:07 PM
Anal cancer screening: a balanced approach is necessary
✅ Just Accepted
#IDTwitter
🔗 https://bit.ly/4oK9kra
✅ Just Accepted
#IDTwitter
🔗 https://bit.ly/4oK9kra
November 12, 2025 at 1:30 AM
That’s a wrap !
Back home after my first « on site » @aasldnews.bsky.social Liver Meeting @ Washington DC
It was my first non-HIV meeting (outside 🇨🇦) in ~ 10 years.
Way overdue 👍
#TLM2025
p.s. The snow was waiting for me…
Back home after my first « on site » @aasldnews.bsky.social Liver Meeting @ Washington DC
It was my first non-HIV meeting (outside 🇨🇦) in ~ 10 years.
Way overdue 👍
#TLM2025
p.s. The snow was waiting for me…
November 11, 2025 at 11:44 PM
That’s a wrap !
Back home after my first « on site » @aasldnews.bsky.social Liver Meeting @ Washington DC
It was my first non-HIV meeting (outside 🇨🇦) in ~ 10 years.
Way overdue 👍
#TLM2025
p.s. The snow was waiting for me…
Back home after my first « on site » @aasldnews.bsky.social Liver Meeting @ Washington DC
It was my first non-HIV meeting (outside 🇨🇦) in ~ 10 years.
Way overdue 👍
#TLM2025
p.s. The snow was waiting for me…
Reposted by Sébastien Poulin
Tobevibart plus elebsiran and tobevibart alone both lowered HDV RNA and ALT levels. The combination resulted in a high incidence of undetectable HDV RNA and an HBsAg level below 10 IU/ml at week 48. Full SOLSTICE phase 2 trial results: nej.md/4qIXpuM
@aasldnews.bsky.social | #TLM25
@aasldnews.bsky.social | #TLM25
November 9, 2025 at 11:05 PM
Tobevibart plus elebsiran and tobevibart alone both lowered HDV RNA and ALT levels. The combination resulted in a high incidence of undetectable HDV RNA and an HBsAg level below 10 IU/ml at week 48. Full SOLSTICE phase 2 trial results: nej.md/4qIXpuM
@aasldnews.bsky.social | #TLM25
@aasldnews.bsky.social | #TLM25
My eyes were bleeding 🩸
(🇮🇳 RCT, HCV, SOF/VEL 8w vs 12w)
(🇮🇳 RCT, HCV, SOF/VEL 8w vs 12w)
November 10, 2025 at 9:54 PM
My eyes were bleeding 🩸
(🇮🇳 RCT, HCV, SOF/VEL 8w vs 12w)
(🇮🇳 RCT, HCV, SOF/VEL 8w vs 12w)
November 10, 2025 at 3:11 PM
November 10, 2025 at 4:29 AM
Reposted by Sébastien Poulin
Should I Worry About the Pasta? The ID Doctor as News Translator
(Hello #IDSky and #Medsky! Trying out some different venues for writing, so hoping you'll subscribe -- it's free!)
open.substack.com/pub/paulsaxm...
(Hello #IDSky and #Medsky! Trying out some different venues for writing, so hoping you'll subscribe -- it's free!)
open.substack.com/pub/paulsaxm...
Should I Worry About the Pasta? The ID Doctor as News Translator
What happens when we get texts about Trader Joe’s fettuccine — and what to do when infections make headlines.
open.substack.com
November 9, 2025 at 9:47 AM
Should I Worry About the Pasta? The ID Doctor as News Translator
(Hello #IDSky and #Medsky! Trying out some different venues for writing, so hoping you'll subscribe -- it's free!)
open.substack.com/pub/paulsaxm...
(Hello #IDSky and #Medsky! Trying out some different venues for writing, so hoping you'll subscribe -- it's free!)
open.substack.com/pub/paulsaxm...
November 8, 2025 at 6:35 PM
November 8, 2025 at 4:25 PM
Washington DC @ #TLM2025
@aasldnews.bsky.social
🔥Hot Topics in Hepatitis B : New Clinical Tools for Hepatitis B Management
(after my 10 km)
@aasldnews.bsky.social
🔥Hot Topics in Hepatitis B : New Clinical Tools for Hepatitis B Management
(after my 10 km)
November 8, 2025 at 12:48 PM
Washington DC @ #TLM2025
@aasldnews.bsky.social
🔥Hot Topics in Hepatitis B : New Clinical Tools for Hepatitis B Management
(after my 10 km)
@aasldnews.bsky.social
🔥Hot Topics in Hepatitis B : New Clinical Tools for Hepatitis B Management
(after my 10 km)
Reposted by Sébastien Poulin
🆕🔥State-of-the-Art Review with 🌟s @trubianojason.bsky.social : Antibiotic Allergy—A Multidisciplinary Approach to Delabeling #idsky
url: academic.oup.com/cid/article/...
url: academic.oup.com/cid/article/...
November 6, 2025 at 8:09 PM
🆕🔥State-of-the-Art Review with 🌟s @trubianojason.bsky.social : Antibiotic Allergy—A Multidisciplinary Approach to Delabeling #idsky
url: academic.oup.com/cid/article/...
url: academic.oup.com/cid/article/...
Reposted by Sébastien Poulin
@glaucomflecken.bsky.social hitting close to home with this ID doc at the soccer game....
Reflexively, I couldn't help screaming in my head...don't put DEET on the net, only use permethrin on clothing!!
#IDSky
www.youtube.com/shorts/Q8UGF...
Reflexively, I couldn't help screaming in my head...don't put DEET on the net, only use permethrin on clothing!!
#IDSky
www.youtube.com/shorts/Q8UGF...
Infectious Disease Doctor Goes To A Soccer Game
YouTube video by Dr. Glaucomflecken
www.youtube.com
November 5, 2025 at 7:39 PM
@glaucomflecken.bsky.social hitting close to home with this ID doc at the soccer game....
Reflexively, I couldn't help screaming in my head...don't put DEET on the net, only use permethrin on clothing!!
#IDSky
www.youtube.com/shorts/Q8UGF...
Reflexively, I couldn't help screaming in my head...don't put DEET on the net, only use permethrin on clothing!!
#IDSky
www.youtube.com/shorts/Q8UGF...
🆕 AASLD/IDSA Practice Guideline on treatment of chronic Hepatitis B
@aasldnews.bsky.social
@idsainfo.bsky.social
journals.lww.com/hep/abstract...
@aasldnews.bsky.social
@idsainfo.bsky.social
journals.lww.com/hep/abstract...
November 5, 2025 at 3:42 AM
🆕 AASLD/IDSA Practice Guideline on treatment of chronic Hepatitis B
@aasldnews.bsky.social
@idsainfo.bsky.social
journals.lww.com/hep/abstract...
@aasldnews.bsky.social
@idsainfo.bsky.social
journals.lww.com/hep/abstract...
Loi 2 : CAQ(A)strophe 💩
November 1, 2025 at 3:20 PM
Loi 2 : CAQ(A)strophe 💩