Sébastien Poulin
@sebpoule.bsky.social
Medical microbiologist & Infectious diseases MD
@ St-Jérôme & Montréal, Québec, 🇨🇦
🔝 Interests HBV HDV HIV & General I.D.
French 🇨🇦 with a 💩 accent
#IDsky #HIVsky #Medsky
@ St-Jérôme & Montréal, Québec, 🇨🇦
🔝 Interests HBV HDV HIV & General I.D.
French 🇨🇦 with a 💩 accent
#IDsky #HIVsky #Medsky
Reposted by Sébastien Poulin
#IDSky I always email residents rotating with me survival tips for their time of the ID consult service. I like to keep this short and high yield but I am constantly editing and improving the tip sheet. What would you add or remove. It cannot be longer that one page 😊.
February 8, 2026 at 10:31 PM
#IDSky I always email residents rotating with me survival tips for their time of the ID consult service. I like to keep this short and high yield but I am constantly editing and improving the tip sheet. What would you add or remove. It cannot be longer that one page 😊.
Reposted by Sébastien Poulin
When I am declared God King Emperor, I am banning Cdiff PCR's
snoop dogg is wearing glasses and a red turtleneck sweater and says i said what i said
ALT: snoop dogg is wearing glasses and a red turtleneck sweater and says i said what i said
media.tenor.com
February 6, 2026 at 7:35 PM
When I am declared God King Emperor, I am banning Cdiff PCR's
Reposted by Sébastien Poulin
My top 10 ID papers for 2025. Full citations and descriptions available at clarityinitiative.org/hot-takes
Also see/hear our Communicable podcast episode on this at communicable.transistor.fm/episodes/com...
What were your top 10? Any thoughts about what I missed welcome!
#IDSky #Top10papers
Also see/hear our Communicable podcast episode on this at communicable.transistor.fm/episodes/com...
What were your top 10? Any thoughts about what I missed welcome!
#IDSky #Top10papers
February 5, 2026 at 11:28 PM
My top 10 ID papers for 2025. Full citations and descriptions available at clarityinitiative.org/hot-takes
Also see/hear our Communicable podcast episode on this at communicable.transistor.fm/episodes/com...
What were your top 10? Any thoughts about what I missed welcome!
#IDSky #Top10papers
Also see/hear our Communicable podcast episode on this at communicable.transistor.fm/episodes/com...
What were your top 10? Any thoughts about what I missed welcome!
#IDSky #Top10papers
Reposted by Sébastien Poulin
Grateful to have the opportunity to share this little piece of my heart. Love is always the answer.
academic.oup.com/cid/advance-...
academic.oup.com/cid/advance-...
February 3, 2026 at 5:01 PM
Grateful to have the opportunity to share this little piece of my heart. Love is always the answer.
academic.oup.com/cid/advance-...
academic.oup.com/cid/advance-...
Reposted by Sébastien Poulin
I highly recommend @patrickching.bsky.social latest commentary in @ashejournal.bsky.social describing:
-the history of contact precautions
-the need for balance ⚖️ between the benefits of gowns/gloves with their cost/environmental impact
www.cambridge.org/core/journal...
#IDSky
-the history of contact precautions
-the need for balance ⚖️ between the benefits of gowns/gloves with their cost/environmental impact
www.cambridge.org/core/journal...
#IDSky
The rise and fall of contact precautions: how does personal protective equipment fit into sustainable healthcare? | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
The rise and fall of contact precautions: how does personal protective equipment fit into sustainable healthcare? - Volume 5 Issue 1
www.cambridge.org
February 1, 2026 at 10:14 PM
I highly recommend @patrickching.bsky.social latest commentary in @ashejournal.bsky.social describing:
-the history of contact precautions
-the need for balance ⚖️ between the benefits of gowns/gloves with their cost/environmental impact
www.cambridge.org/core/journal...
#IDSky
-the history of contact precautions
-the need for balance ⚖️ between the benefits of gowns/gloves with their cost/environmental impact
www.cambridge.org/core/journal...
#IDSky
Reposted by Sébastien Poulin
Finally, a mainstream media article on a subject many of we infectious disease docs have to deal with on an almost daily basis.
It correctly identifies a “wellness” industry profit motive that drives the misinformation on this subject. www.cbc.ca/news/investi...
It correctly identifies a “wellness” industry profit motive that drives the misinformation on this subject. www.cbc.ca/news/investi...
Why do so many celebrities say they have Lyme disease? | CBC News
Chronic Lyme disease isn't recognized by conventional medicine. It's a controversial term used by some alternative practitioners to describe pain, fatigue and neurological symptoms they attribute to a...
www.cbc.ca
January 31, 2026 at 2:18 PM
Finally, a mainstream media article on a subject many of we infectious disease docs have to deal with on an almost daily basis.
It correctly identifies a “wellness” industry profit motive that drives the misinformation on this subject. www.cbc.ca/news/investi...
It correctly identifies a “wellness” industry profit motive that drives the misinformation on this subject. www.cbc.ca/news/investi...
Reposted by Sébastien Poulin
Browse the best of 2025! The Editors-in-Chief of cidjournal.bsky.social, jidjournal.bsky.social & ofidjournal.bsky.social have selected a collection of outstanding articles from 2025. Explore research on long COVID, AMR, HIV, influenza, vaccines & more: https://bit.ly/49Xgge6
paulsaxmd.bsky.social
paulsaxmd.bsky.social
January 30, 2026 at 9:53 PM
Browse the best of 2025! The Editors-in-Chief of cidjournal.bsky.social, jidjournal.bsky.social & ofidjournal.bsky.social have selected a collection of outstanding articles from 2025. Explore research on long COVID, AMR, HIV, influenza, vaccines & more: https://bit.ly/49Xgge6
paulsaxmd.bsky.social
paulsaxmd.bsky.social
Reposted by Sébastien Poulin
Subcutaneous antibiotic administration is increasingly recognized as a valuable alternative to intravenous therapy in selected clinical contexts. In CID, authors summarize current clinical experience, PK/PD data, and technical aspects of subcutaneous infusion. https://bit.ly/3NB1jH5
When and How to Use Subcutaneous Antibiotics
Subcutaneous administration of selected antibiotics provides a practical, safe alternative to intravenous therapy in patients with poor venous access, in o
academic.oup.com
January 28, 2026 at 6:09 PM
Subcutaneous antibiotic administration is increasingly recognized as a valuable alternative to intravenous therapy in selected clinical contexts. In CID, authors summarize current clinical experience, PK/PD data, and technical aspects of subcutaneous infusion. https://bit.ly/3NB1jH5
Reposted by Sébastien Poulin
OI
YOU
… Podcast on Azole Antifungals.
Would be a shame if you reposted it to AAAAAAALLL your followers, and liked it and commented on what you thought of it below
PLEASE DON’T DO THAT we hate popularity!!
#IDsky #microsky #fungi
podcasts.apple.com/gb/podcast/i...
YOU
… Podcast on Azole Antifungals.
Would be a shame if you reposted it to AAAAAAALLL your followers, and liked it and commented on what you thought of it below
PLEASE DON’T DO THAT we hate popularity!!
#IDsky #microsky #fungi
podcasts.apple.com/gb/podcast/i...
130. Azole Antifungals
Podcast Episode · ID:IOTS - Infectious Disease Insight Of Two Specialists · 26/01/2026 · 32m
podcasts.apple.com
January 27, 2026 at 6:37 PM
OI
YOU
… Podcast on Azole Antifungals.
Would be a shame if you reposted it to AAAAAAALLL your followers, and liked it and commented on what you thought of it below
PLEASE DON’T DO THAT we hate popularity!!
#IDsky #microsky #fungi
podcasts.apple.com/gb/podcast/i...
YOU
… Podcast on Azole Antifungals.
Would be a shame if you reposted it to AAAAAAALLL your followers, and liked it and commented on what you thought of it below
PLEASE DON’T DO THAT we hate popularity!!
#IDsky #microsky #fungi
podcasts.apple.com/gb/podcast/i...
Reposted by Sébastien Poulin
🧵 Essential ID Papers for 2025: A Clinician’s Guide
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
December 22, 2025 at 3:22 PM
🧵 Essential ID Papers for 2025: A Clinician’s Guide
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
Reposted by Sébastien Poulin
Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis
Congratulations to David Meya, Fiona Cresswell, @natebahrid.bsky.social @drboulware.bsky.social & co on this important trial
No mortality benefit to high dose rifampin in adults with TB meningitis
www.nejm.org/doi/full/10....
Congratulations to David Meya, Fiona Cresswell, @natebahrid.bsky.social @drboulware.bsky.social & co on this important trial
No mortality benefit to high dose rifampin in adults with TB meningitis
www.nejm.org/doi/full/10....
December 18, 2025 at 12:39 AM
Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis
Congratulations to David Meya, Fiona Cresswell, @natebahrid.bsky.social @drboulware.bsky.social & co on this important trial
No mortality benefit to high dose rifampin in adults with TB meningitis
www.nejm.org/doi/full/10....
Congratulations to David Meya, Fiona Cresswell, @natebahrid.bsky.social @drboulware.bsky.social & co on this important trial
No mortality benefit to high dose rifampin in adults with TB meningitis
www.nejm.org/doi/full/10....
Reposted by Sébastien Poulin
🆕⚡🧠HARVEST TRIAL:More Rifampin,Same Fate: High-Dose Rifampin Fails to Shift the Needle in TB Meningitis,NEJM,2025
Despite better theoretical CNS penetration,high-dose oral rifampin did not improve survival in adult TB meningitis & potential harm cannot be excluded #idsky
www.nejm.org/doi/full/10....
Despite better theoretical CNS penetration,high-dose oral rifampin did not improve survival in adult TB meningitis & potential harm cannot be excluded #idsky
www.nejm.org/doi/full/10....
Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis | NEJM
Tuberculous meningitis is often lethal, and many survivors have disabilities despite antimicrobial treatment and adjunctive glucocorticoid therapy. Standard-dose rifampin has limited central nervou...
www.nejm.org
December 18, 2025 at 3:51 AM
🆕⚡🧠HARVEST TRIAL:More Rifampin,Same Fate: High-Dose Rifampin Fails to Shift the Needle in TB Meningitis,NEJM,2025
Despite better theoretical CNS penetration,high-dose oral rifampin did not improve survival in adult TB meningitis & potential harm cannot be excluded #idsky
www.nejm.org/doi/full/10....
Despite better theoretical CNS penetration,high-dose oral rifampin did not improve survival in adult TB meningitis & potential harm cannot be excluded #idsky
www.nejm.org/doi/full/10....
Et voilà !
On le dit depuis le début… et c’est la même chose pour les spécialistes
Êtes-vous vraiment surpris que le ministère aurait pu se tromper dans ses calculs ?
Non !
www.lapresse.ca/affaires/chr...
On le dit depuis le début… et c’est la même chose pour les spécialistes
Êtes-vous vraiment surpris que le ministère aurait pu se tromper dans ses calculs ?
Non !
www.lapresse.ca/affaires/chr...
Rémunération des médecins | Le Ministère a-t-il fait des erreurs de calcul ?
Le ministère de la Santé a-t-il fait des erreurs importantes dans ses paramètres de rémunération des médecins de famille inscrits dans la loi 2 ?
www.lapresse.ca
December 6, 2025 at 2:13 PM
Et voilà !
On le dit depuis le début… et c’est la même chose pour les spécialistes
Êtes-vous vraiment surpris que le ministère aurait pu se tromper dans ses calculs ?
Non !
www.lapresse.ca/affaires/chr...
On le dit depuis le début… et c’est la même chose pour les spécialistes
Êtes-vous vraiment surpris que le ministère aurait pu se tromper dans ses calculs ?
Non !
www.lapresse.ca/affaires/chr...
Reposted by Sébastien Poulin
𝗕𝗮𝗰𝘁𝗲𝗰 𝗙𝗫 @ 𝗦𝘁-𝗝𝗲𝗿𝗼𝗺𝗲
New device for BC next monday!
Main changes :
1. New bottles w/ thin cap
2. Finally enough space for 4 bottles/pt! Bacteremia detection ability expected to go up by ~ 5%
3. We’ll start to use diversion to reduce contamination rates by an expected 60%
#IDSky #MicroSky
New device for BC next monday!
Main changes :
1. New bottles w/ thin cap
2. Finally enough space for 4 bottles/pt! Bacteremia detection ability expected to go up by ~ 5%
3. We’ll start to use diversion to reduce contamination rates by an expected 60%
#IDSky #MicroSky
December 5, 2025 at 2:16 PM
Reposted by Sébastien Poulin
On World AIDS Day, remember that HIV risk often changes over time & that our prevention tools keep expanding.
PrEP, PEP & PEP-in-Pocket ("PIP") offer strong, flexible protection.
A "buffet" approach lets people choose what best fits their lives.
tinyurl.com/2zkf3hak
PrEP, PEP & PEP-in-Pocket ("PIP") offer strong, flexible protection.
A "buffet" approach lets people choose what best fits their lives.
tinyurl.com/2zkf3hak
December 1, 2025 at 5:22 PM
On World AIDS Day, remember that HIV risk often changes over time & that our prevention tools keep expanding.
PrEP, PEP & PEP-in-Pocket ("PIP") offer strong, flexible protection.
A "buffet" approach lets people choose what best fits their lives.
tinyurl.com/2zkf3hak
PrEP, PEP & PEP-in-Pocket ("PIP") offer strong, flexible protection.
A "buffet" approach lets people choose what best fits their lives.
tinyurl.com/2zkf3hak
Reposted by Sébastien Poulin
Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice
🔗 https://bit.ly/4pmCEDJ
🔗 https://bit.ly/4pmCEDJ
November 29, 2025 at 6:40 PM
Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice
🔗 https://bit.ly/4pmCEDJ
🔗 https://bit.ly/4pmCEDJ
Reposted by Sébastien Poulin
Can we really be grateful for anything in the ID world in 2025?
Sure -- plenty of great advances!
Here are a half-dozen to celebrate (and be grateful for) in 2025, believe it or not. #idsky
blogs.jwatch.org/hiv-id-obser...
Sure -- plenty of great advances!
Here are a half-dozen to celebrate (and be grateful for) in 2025, believe it or not. #idsky
blogs.jwatch.org/hiv-id-obser...
ID Things to Be Grateful for -- 2025 Edition
Looking back on these annual Thanksgiving posts, I notice an odd pattern: every few years, the intro turns into a kind of apology. As in, Yes, I know the title sounds upbeat, please don’t attack me. T...
blogs.jwatch.org
November 25, 2025 at 2:29 AM
Can we really be grateful for anything in the ID world in 2025?
Sure -- plenty of great advances!
Here are a half-dozen to celebrate (and be grateful for) in 2025, believe it or not. #idsky
blogs.jwatch.org/hiv-id-obser...
Sure -- plenty of great advances!
Here are a half-dozen to celebrate (and be grateful for) in 2025, believe it or not. #idsky
blogs.jwatch.org/hiv-id-obser...
Reposted by Sébastien Poulin
Inspired by this rage-inducing ad, I offer 3 big misses on antibiotics that need to die.
paulsaxmd.substack.com/p/three-myth...
paulsaxmd.substack.com/p/three-myth...
Three Myths About Antibiotics We Really Need to Retire
Sneezes, penicillin allergies, and those strangely sacred 5- and 7-day courses.
paulsaxmd.substack.com
November 21, 2025 at 3:53 PM
Inspired by this rage-inducing ad, I offer 3 big misses on antibiotics that need to die.
paulsaxmd.substack.com/p/three-myth...
paulsaxmd.substack.com/p/three-myth...
Fascinating CID Brief Report
➡️Safe implementation of novel HBV-inactive cART for people living with HIV and prior HBV exposure is of paramount importance and better clinical trial and real-world data is essential to inform best practice
➡️Safe implementation of novel HBV-inactive cART for people living with HIV and prior HBV exposure is of paramount importance and better clinical trial and real-world data is essential to inform best practice
Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice
✅ Just Accepted
🔗 https://bit.ly/4pmCEDJ
✅ Just Accepted
🔗 https://bit.ly/4pmCEDJ
November 23, 2025 at 7:06 PM
Fascinating CID Brief Report
➡️Safe implementation of novel HBV-inactive cART for people living with HIV and prior HBV exposure is of paramount importance and better clinical trial and real-world data is essential to inform best practice
➡️Safe implementation of novel HBV-inactive cART for people living with HIV and prior HBV exposure is of paramount importance and better clinical trial and real-world data is essential to inform best practice
Fascinating CID Brief Report #HIVsky #IDsky
« Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice»
(Thank you @josephmarcusid.medsky.social for flagging it)
academic.oup.com/cid/article/...
« Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice»
(Thank you @josephmarcusid.medsky.social for flagging it)
academic.oup.com/cid/article/...
Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice
Abstract. The potential for hepatitis B reactivation must be considered when switching people with HIV and prior hepatitis B exposure away from tenofovir-c
academic.oup.com
November 23, 2025 at 1:40 AM
Fascinating CID Brief Report #HIVsky #IDsky
« Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice»
(Thank you @josephmarcusid.medsky.social for flagging it)
academic.oup.com/cid/article/...
« Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice»
(Thank you @josephmarcusid.medsky.social for flagging it)
academic.oup.com/cid/article/...
Reposted by Sébastien Poulin
A great @cidjournal.bsky.social case series that led to lots of discussion with the fellows today- 4 🇬🇧 pts with HBV reactivation after change off of a TAF-based HIV regimen
Pt1/4: +HBcAB, -HBVsAg, -HBVsAB
Pt2/3: +HBcAB, -HBVsAg,+HBVsAB
#IDSky
academic.oup.com/cid/advance-...
Pt1/4: +HBcAB, -HBVsAg, -HBVsAB
Pt2/3: +HBcAB, -HBVsAg,+HBVsAB
#IDSky
academic.oup.com/cid/advance-...
Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice
Abstract. The potential for hepatitis B reactivation must be considered when switching people with HIV and prior hepatitis B exposure away from tenofovir-c
academic.oup.com
November 22, 2025 at 12:44 AM
A great @cidjournal.bsky.social case series that led to lots of discussion with the fellows today- 4 🇬🇧 pts with HBV reactivation after change off of a TAF-based HIV regimen
Pt1/4: +HBcAB, -HBVsAg, -HBVsAB
Pt2/3: +HBcAB, -HBVsAg,+HBVsAB
#IDSky
academic.oup.com/cid/advance-...
Pt1/4: +HBcAB, -HBVsAg, -HBVsAB
Pt2/3: +HBcAB, -HBVsAg,+HBVsAB
#IDSky
academic.oup.com/cid/advance-...
Reposted by Sébastien Poulin
🆕🔥🦴 Our 2025 Update to @wiki-guidelines.bsky.social for the Management of Pyogenic Osteomyelitis in Adults 🌟 @bradspellberg.bsky.social
🔗 [link] #idsky
www.amjmed.com/article/S000...
🔗 [link] #idsky
www.amjmed.com/article/S000...
November 19, 2025 at 4:25 PM
🆕🔥🦴 Our 2025 Update to @wiki-guidelines.bsky.social for the Management of Pyogenic Osteomyelitis in Adults 🌟 @bradspellberg.bsky.social
🔗 [link] #idsky
www.amjmed.com/article/S000...
🔗 [link] #idsky
www.amjmed.com/article/S000...
Le président du CMDP, Michel L’Allier;« On travaille beaucoup avec des cancers, et nous, qu’est-ce qu’on fait quand il y a un cancer ? On l’enlève. Quand une loi n’est pas bonne et que c’est un cancer pour le système de santé, on l’enlève »
#Loi2 = ⚠️ et 💩
www.lapresse.ca/actualites/s...
#Loi2 = ⚠️ et 💩
www.lapresse.ca/actualites/s...
Loi sur la rémunération des médecins | Les pédiatres de plusieurs hôpitaux manifestent
Des manifestations se sont déroulées dimanche aux quatre centres hospitaliers universitaires de pédiatrie de la province, en opposition au projet de loi 2, qui vise entre autres à lier la rémunération...
www.lapresse.ca
November 16, 2025 at 11:19 PM
Le président du CMDP, Michel L’Allier;« On travaille beaucoup avec des cancers, et nous, qu’est-ce qu’on fait quand il y a un cancer ? On l’enlève. Quand une loi n’est pas bonne et que c’est un cancer pour le système de santé, on l’enlève »
#Loi2 = ⚠️ et 💩
www.lapresse.ca/actualites/s...
#Loi2 = ⚠️ et 💩
www.lapresse.ca/actualites/s...
Je suis un médecin.
Je ne quitterai pas le Québec.
Je serai « ailleurs » dans ma tête.
Tout simplement.
Strict minimum.
Zéro motivation.
#JeMeSouviens #Loi2
Je ne quitterai pas le Québec.
Je serai « ailleurs » dans ma tête.
Tout simplement.
Strict minimum.
Zéro motivation.
#JeMeSouviens #Loi2
November 14, 2025 at 11:43 AM
Je suis un médecin.
Je ne quitterai pas le Québec.
Je serai « ailleurs » dans ma tête.
Tout simplement.
Strict minimum.
Zéro motivation.
#JeMeSouviens #Loi2
Je ne quitterai pas le Québec.
Je serai « ailleurs » dans ma tête.
Tout simplement.
Strict minimum.
Zéro motivation.
#JeMeSouviens #Loi2