Sarah Borrie
@sborrie.bsky.social
Wandering neuroscientist. Currently De Strooper lab at @cbdresearch.bsky.social, incoming Senior research fellow at @aucklanduni.bsky.social in 2026.
alzheimer's, autism, rasopathies, microglia
alzheimer's, autism, rasopathies, microglia
Reposted by Sarah Borrie
‼️Lymphatic Education&Research Network-GRC Scholarships‼️
LE&RN is awarding 10 × $1,000 scholarships to early investigators to attend 2026 Lymphatics GRC March 1 – March 6, 2026, Lucca (Barga), Italy.
🗓 Apply by Dec 8, 2025!
form.jotform.com/LERN/2026-gr...
LE&RN is awarding 10 × $1,000 scholarships to early investigators to attend 2026 Lymphatics GRC March 1 – March 6, 2026, Lucca (Barga), Italy.
🗓 Apply by Dec 8, 2025!
form.jotform.com/LERN/2026-gr...
October 31, 2025 at 5:11 PM
‼️Lymphatic Education&Research Network-GRC Scholarships‼️
LE&RN is awarding 10 × $1,000 scholarships to early investigators to attend 2026 Lymphatics GRC March 1 – March 6, 2026, Lucca (Barga), Italy.
🗓 Apply by Dec 8, 2025!
form.jotform.com/LERN/2026-gr...
LE&RN is awarding 10 × $1,000 scholarships to early investigators to attend 2026 Lymphatics GRC March 1 – March 6, 2026, Lucca (Barga), Italy.
🗓 Apply by Dec 8, 2025!
form.jotform.com/LERN/2026-gr...
Reposted by Sarah Borrie
Cool neurogenesis meeting in the Swiss Alps!!
'Neurogenesis from development to adulthood in health and disease'
To submit an application: asconameeting@unige.ch
'Neurogenesis from development to adulthood in health and disease'
To submit an application: asconameeting@unige.ch
November 11, 2025 at 4:30 PM
Cool neurogenesis meeting in the Swiss Alps!!
'Neurogenesis from development to adulthood in health and disease'
To submit an application: asconameeting@unige.ch
'Neurogenesis from development to adulthood in health and disease'
To submit an application: asconameeting@unige.ch
Reposted by Sarah Borrie
📢 June 8th-9th 2026 Bristol University 📢
We have partnered with @physoc.bsky.social to organise the 2nd meeting Bristol. It is a privilege to announce Professor Baljit Khakh, FRS will join us in the UK.
Check out the exciting programme here:
www.physoc.org/events/uk-gl...
#neuroskyence #glia
We have partnered with @physoc.bsky.social to organise the 2nd meeting Bristol. It is a privilege to announce Professor Baljit Khakh, FRS will join us in the UK.
Check out the exciting programme here:
www.physoc.org/events/uk-gl...
#neuroskyence #glia
UK Glia 2026
UK Glia 2026 meeting will highlight the pivotal role of glia in brain physiology, offering invaluable insights for those investigating glia function in both health and disease. Find out more about the...
www.physoc.org
October 20, 2025 at 12:54 PM
📢 June 8th-9th 2026 Bristol University 📢
We have partnered with @physoc.bsky.social to organise the 2nd meeting Bristol. It is a privilege to announce Professor Baljit Khakh, FRS will join us in the UK.
Check out the exciting programme here:
www.physoc.org/events/uk-gl...
#neuroskyence #glia
We have partnered with @physoc.bsky.social to organise the 2nd meeting Bristol. It is a privilege to announce Professor Baljit Khakh, FRS will join us in the UK.
Check out the exciting programme here:
www.physoc.org/events/uk-gl...
#neuroskyence #glia
Reposted by Sarah Borrie
Share this funding opportunity! We offer the Fellows-to-Faculty program to nurture new talent in the basic sciences and to broaden the community of scientists contributing to Simons Foundation Autism Research Initiative (SFARI) and Simons Collaboration on Plasticity and the Aging Brain (SCPAB).
Applications for our Fellows-to-Faculty Award are now open! This program supports early career scientists in #autism or #neuroscience research by facilitating their transition into tenure-track faculty positions. Apply by 1/14/2026: www.simonsfoundation.org/2025/10/31/a... #science
Applications for Fellows-to-Faculty Awards Now Open
Applications for Fellows-to-Faculty Awards Now Open on Simons Foundation
www.simonsfoundation.org
November 3, 2025 at 7:26 PM
Share this funding opportunity! We offer the Fellows-to-Faculty program to nurture new talent in the basic sciences and to broaden the community of scientists contributing to Simons Foundation Autism Research Initiative (SFARI) and Simons Collaboration on Plasticity and the Aging Brain (SCPAB).
Reposted by Sarah Borrie
@andreaserio.bsky.social and I are recruiting a postdoc to lead an exciting MNDA-funded project using multi-omics to study long axons in motor neurons and how they shape susceptibility to #ALS.
Get in touch for any questions and apply by 2 December:
my.corehr.com/pls/kclrecru...
Get in touch for any questions and apply by 2 December:
my.corehr.com/pls/kclrecru...
November 4, 2025 at 5:33 PM
@andreaserio.bsky.social and I are recruiting a postdoc to lead an exciting MNDA-funded project using multi-omics to study long axons in motor neurons and how they shape susceptibility to #ALS.
Get in touch for any questions and apply by 2 December:
my.corehr.com/pls/kclrecru...
Get in touch for any questions and apply by 2 December:
my.corehr.com/pls/kclrecru...
Reposted by Sarah Borrie
What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope!
Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.
Read the paper here: www.science.org/doi/10.1126/...
(1/10)
Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.
Read the paper here: www.science.org/doi/10.1126/...
(1/10)
July 14, 2025 at 4:55 PM
What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope!
Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.
Read the paper here: www.science.org/doi/10.1126/...
(1/10)
Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.
Read the paper here: www.science.org/doi/10.1126/...
(1/10)
Reposted by Sarah Borrie
Delighted to speak at the @microgliaseries.bsky.social on Monday. Everyone welcome to join us online 🧬✨
New webinar coming next MONDAY‼️ Sarah Marzi from UK Dementia Research Institute @sj-marzi.bsky.social will be our next speaker on November 3rd. Check all the information in the flyer and add it to your calendar!
October 29, 2025 at 1:26 PM
Delighted to speak at the @microgliaseries.bsky.social on Monday. Everyone welcome to join us online 🧬✨
Reposted by Sarah Borrie
Anderson and colleagues review studies demonstrating that neuroimmune mechanisms play a critical role in both healthy neurodevelopment and the pathology of neurodevelopmental disorders.
Neuroimmune mechanisms of neurodevelopmental disorders
Neurodevelopmental disorders (NDDs) are characterized by alterations in typical brain
development. The immune system is increasingly implicated in NDDs and may contribute
to both susceptibility and pa...
www.biologicalpsychiatryjournal.com
October 29, 2025 at 3:19 PM
Anderson and colleagues review studies demonstrating that neuroimmune mechanisms play a critical role in both healthy neurodevelopment and the pathology of neurodevelopmental disorders.
Reposted by Sarah Borrie
New TYP lab publication led by PhD student @alexlish.bsky.social out today in @cp-cellreports.bsky.social! We present a reproducible neuron-astrocyte-microglia tri-culture model to better reproduce intercellular interactions in Alzheimer's disease. Read more here: www.cell.com/cell-reports...
Astrocyte induction of disease-associated microglia is suppressed by acute exposure to fAD neurons in human iPSC triple cultures
Lish et al. present a co-culture system of iPSC-derived human microglia, astrocytes,
and neurons to investigate intercellular communication across different environmental
and genetic contexts. Transcr...
www.cell.com
June 5, 2025 at 12:49 AM
New TYP lab publication led by PhD student @alexlish.bsky.social out today in @cp-cellreports.bsky.social! We present a reproducible neuron-astrocyte-microglia tri-culture model to better reproduce intercellular interactions in Alzheimer's disease. Read more here: www.cell.com/cell-reports...
Reposted by Sarah Borrie
Just out, recent work from the Plemel lab by the talented Brady Hammond. We sought to understand the factors that regulate microglial proliferation during development.
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
CSF1R ligands promote microglial proliferation but are not the sole regulators of developmental microglial proliferation
Summary: In vitro and in vivo investigations indicate that CSF1 and IL34 may partially regulate the developmental proliferation of microglia in the mouse hippocampus and cortex, but an additional laye...
journals.biologists.com
June 3, 2025 at 4:14 PM
Just out, recent work from the Plemel lab by the talented Brady Hammond. We sought to understand the factors that regulate microglial proliferation during development.
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
Reposted by Sarah Borrie
Postdoc role in the De Strooper / Arancibia Lab in the UK DRI–UCL exploring how Alzheimer’s risk genes affect microglial function and antigen presentation using cutting-edge models and techniques. Closing date: 27th July. @ukdri.ac.uk
www.dementiaresearcher.nihr.ac.uk/job/research...
www.dementiaresearcher.nihr.ac.uk/job/research...
Research Fellow: Immunity in Alzheimer’s Disease
Postdoc role at UK DRI–UCL exploring how Alzheimer’s risk genes affect microglial function and antigen presentation using cutting-edge models and techniques.
www.dementiaresearcher.nihr.ac.uk
May 28, 2025 at 8:34 AM
Postdoc role in the De Strooper / Arancibia Lab in the UK DRI–UCL exploring how Alzheimer’s risk genes affect microglial function and antigen presentation using cutting-edge models and techniques. Closing date: 27th July. @ukdri.ac.uk
www.dementiaresearcher.nihr.ac.uk/job/research...
www.dementiaresearcher.nihr.ac.uk/job/research...
Reposted by Sarah Borrie
URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯
Any lab using @flybase.bsky.social please donate using the link in post below.
This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
Any lab using @flybase.bsky.social please donate using the link in post below.
This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate.
www.philanthropy.cam.ac.uk/give-to-camb...
www.philanthropy.cam.ac.uk/give-to-camb...
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
www.philanthropy.cam.ac.uk
June 3, 2025 at 5:20 PM
URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯
Any lab using @flybase.bsky.social please donate using the link in post below.
This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
Any lab using @flybase.bsky.social please donate using the link in post below.
This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
Reposted by Sarah Borrie
Now online! Immunotherapy-related cognitive impairment after CAR T cell therapy in mice
Immunotherapy-related cognitive impairment after CAR T cell therapy in mice
CAR T cell therapy can cause cognitive impairment in mouse models with central nervous system (CNS) and non-CNS cancers by inducing persistent neuroinflammation, thereby disrupting oligodendroglial homeostasis and hippocampal neurogenesis, which can be rescued by microglial depletion or CCR3 blockade.
dlvr.it
May 12, 2025 at 2:59 PM
Now online! Immunotherapy-related cognitive impairment after CAR T cell therapy in mice
Reposted by Sarah Borrie
Hey @jacksonlab.bsky.social
& neurotwitter, Have you had issues with this amyloidosis mouse line: B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax,
Stock No: 005864. Only 30% of 11 month old Heterozygous Tg mice show plaques???
& neurotwitter, Have you had issues with this amyloidosis mouse line: B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax,
Stock No: 005864. Only 30% of 11 month old Heterozygous Tg mice show plaques???
May 12, 2025 at 10:42 AM
Hey @jacksonlab.bsky.social
& neurotwitter, Have you had issues with this amyloidosis mouse line: B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax,
Stock No: 005864. Only 30% of 11 month old Heterozygous Tg mice show plaques???
& neurotwitter, Have you had issues with this amyloidosis mouse line: B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax,
Stock No: 005864. Only 30% of 11 month old Heterozygous Tg mice show plaques???
Reposted by Sarah Borrie
⬇️This is happening today⬇️
See you all there!
See you all there!
📢New webinar coming soon📢
There has been a schedule change for tomorrow: Federico Soria @soriafn.bsky.social, expert in matrix-microglia interactions, will be our next speaker on May 6th (tomorrow!). Check all the information in the flyer and add it to your calendar! @achucarro.bsky.social
There has been a schedule change for tomorrow: Federico Soria @soriafn.bsky.social, expert in matrix-microglia interactions, will be our next speaker on May 6th (tomorrow!). Check all the information in the flyer and add it to your calendar! @achucarro.bsky.social
May 6, 2025 at 12:09 PM
⬇️This is happening today⬇️
See you all there!
See you all there!
Reposted by Sarah Borrie
Attention South Island-based experts looking for media training!
There are still a handful of spots in our 5-6 June Chch workshop (including at least one fees-free space).
We've extended the deadline to apply, and applications this week are likely to be accepted.
smc.nz/science-media-savvy/#apply
There are still a handful of spots in our 5-6 June Chch workshop (including at least one fees-free space).
We've extended the deadline to apply, and applications this week are likely to be accepted.
smc.nz/science-media-savvy/#apply
Science Media SAVVY
Our flagship media training increases confidence and skills to help researchers to engage more effectively with the wider public through broadcast, print and social media. Apply below.
We create a uni...
www.sciencemediacentre.co.nz
May 5, 2025 at 3:59 AM
Attention South Island-based experts looking for media training!
There are still a handful of spots in our 5-6 June Chch workshop (including at least one fees-free space).
We've extended the deadline to apply, and applications this week are likely to be accepted.
smc.nz/science-media-savvy/#apply
There are still a handful of spots in our 5-6 June Chch workshop (including at least one fees-free space).
We've extended the deadline to apply, and applications this week are likely to be accepted.
smc.nz/science-media-savvy/#apply
Reposted by Sarah Borrie
Our perspective in @natrevimmunol.nature.com on new concepts in neuroimmune interactions that have challenged the old dogma that immune privilege is a result of the isolation of the nervous and immune systems.
@jonykipnis.bsky.social
www.nature.com/articles/s41...
@jonykipnis.bsky.social
www.nature.com/articles/s41...
Redefining CNS immune privilege - Nature Reviews Immunology
In this Perspective, Smyth and Kipnis reappraise the concept of immune privilege in the central nervous system. Although immune privilege was originally thought to involve isolation of the central ner...
www.nature.com
May 2, 2025 at 8:05 PM
Our perspective in @natrevimmunol.nature.com on new concepts in neuroimmune interactions that have challenged the old dogma that immune privilege is a result of the isolation of the nervous and immune systems.
@jonykipnis.bsky.social
www.nature.com/articles/s41...
@jonykipnis.bsky.social
www.nature.com/articles/s41...
Reposted by Sarah Borrie
New TYP lab paper out today in @cp-neuron.bsky.social led by PhD student @alexlish.bsky.social! We took a deep dive into the mechanisms underlying CLU in AD using innovative iPSC, mouse, and human data approaches. Be sure to give it a read!
www.cell.com/neuron/abstr...
www.cell.com/neuron/abstr...
CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density
Lish et al. reveal that AD-protective CLU alleles enhance CLU upregulation in response
to accumulated neuropathology, thereby dampening inflammatory signaling between microglia
and astrocytes. Using s...
www.cell.com
April 30, 2025 at 3:56 PM
New TYP lab paper out today in @cp-neuron.bsky.social led by PhD student @alexlish.bsky.social! We took a deep dive into the mechanisms underlying CLU in AD using innovative iPSC, mouse, and human data approaches. Be sure to give it a read!
www.cell.com/neuron/abstr...
www.cell.com/neuron/abstr...
Reposted by Sarah Borrie
Excited for this meeting ! Please share and pass the word
#ReThinkNeuroimmunology
3 day think tank exploring the biggest discoveries & breakthroughs in neuroimmunology.
Organized by @quintanalabhms.bsky.social @bethstevenslab.bsky.social @jonykipnis.bsky.social @idoamitlab.bsky.social #RejaneRua
Registrations 🔗 genelayinstitute.org/rtn/
3 day think tank exploring the biggest discoveries & breakthroughs in neuroimmunology.
Organized by @quintanalabhms.bsky.social @bethstevenslab.bsky.social @jonykipnis.bsky.social @idoamitlab.bsky.social #RejaneRua
Registrations 🔗 genelayinstitute.org/rtn/
.@washumedicine.bsky.social @weizmanninstitute.bsky.social @genelayinstitute.bsky.social @massgenbrigham.bsky.social
April 24, 2025 at 9:25 PM
Excited for this meeting ! Please share and pass the word
Reposted by Sarah Borrie
OK here it is, the moment you have all been waiting for! Our advert for 5 posts here at Glasgow: Cognitive neuroscience/psychology. Closing date May 12 - please spread the word
www.nature.com/naturecareer...
www.nature.com/naturecareer...
March 28, 2025 at 7:06 AM
OK here it is, the moment you have all been waiting for! Our advert for 5 posts here at Glasgow: Cognitive neuroscience/psychology. Closing date May 12 - please spread the word
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Reposted by Sarah Borrie
As much as I’ve loved so many of the #StandUpForScience signs, this one is my favourite (but what else would you expect from Ms Macrophage).
March 8, 2025 at 2:17 AM
As much as I’ve loved so many of the #StandUpForScience signs, this one is my favourite (but what else would you expect from Ms Macrophage).
Reposted by Sarah Borrie
Exciting new role for a Computational Genomics Research Associate in the lab of @sj-marzi.bsky.social at the UK DRI at King's!
Lead projects exploring the epigenome and transcriptome of brain cells in neurodegenerative diseases 🧠
🗓️ Deadline: 08 March 2025
Full info & to apply 👉 shorturl.at/fk7jS
Lead projects exploring the epigenome and transcriptome of brain cells in neurodegenerative diseases 🧠
🗓️ Deadline: 08 March 2025
Full info & to apply 👉 shorturl.at/fk7jS
February 27, 2025 at 12:55 PM
Exciting new role for a Computational Genomics Research Associate in the lab of @sj-marzi.bsky.social at the UK DRI at King's!
Lead projects exploring the epigenome and transcriptome of brain cells in neurodegenerative diseases 🧠
🗓️ Deadline: 08 March 2025
Full info & to apply 👉 shorturl.at/fk7jS
Lead projects exploring the epigenome and transcriptome of brain cells in neurodegenerative diseases 🧠
🗓️ Deadline: 08 March 2025
Full info & to apply 👉 shorturl.at/fk7jS
Reposted by Sarah Borrie
Many Alzheimer’s researchers are also unhappy with Piller’s recent book and its negative characterization of the field, in which he inflates the significance of isolated fraud cases to argue that the entire field is corrupt. Here’s a rebuttal from my colleague Dennis Selkoe, published in STAT News:
There is no ‘amyloid cabal’ in Alzheimer’s research
“There exists no ‘amyloid cabal’” in Alzheimer’s research, neurologist Dennis Selkoe writes in response to Charles Piller’s “Doctored.”
www.statnews.com
March 4, 2025 at 10:50 PM
Many Alzheimer’s researchers are also unhappy with Piller’s recent book and its negative characterization of the field, in which he inflates the significance of isolated fraud cases to argue that the entire field is corrupt. Here’s a rebuttal from my colleague Dennis Selkoe, published in STAT News:
Reposted by Sarah Borrie
If you want to learn about Charlie Piller's journalistic integrity, read this (long) thread.
bsky.app/profile/jere...
It is pretty telling...sensationalism without regard to getting the facts right.
bsky.app/profile/jere...
It is pretty telling...sensationalism without regard to getting the facts right.
Yea, but a lot of the important Alzheimer's papers are considered, in part, fraudulent (Charles Pillar's book "Doctored") There is a lot of tax payer money on research wasted on 1.) irreproducible results due to mistakes/fraud, 2.) deadwood faculty salaries, 3.) absurd journal subscription rates.
March 4, 2025 at 12:10 AM
If you want to learn about Charlie Piller's journalistic integrity, read this (long) thread.
bsky.app/profile/jere...
It is pretty telling...sensationalism without regard to getting the facts right.
bsky.app/profile/jere...
It is pretty telling...sensationalism without regard to getting the facts right.
Reposted by Sarah Borrie
Multiple group leader positions in developmental biology in @ibdm.bsky.social Marseille, at an institute that produces some great work.
We Are Recruiting Group Leaders - IBDM | Institut de Biologie du Développement de Marseille
The Institut de Biologie du Développement de Marseille (IBDM) is inviting applications for group leader positions. We are seeking innovative researchers who aim to address fundamental questions in bio...
staging.ibdm.univ-amu.fr
March 4, 2025 at 10:15 AM
Multiple group leader positions in developmental biology in @ibdm.bsky.social Marseille, at an institute that produces some great work.