Biological Psychiatry
@biologicalpsych.bsky.social
Official account for the Biological Psychiatry family of journals.
Publishing cutting-edge research in psychiatric neuroscience, cognitive neuroimaging, and global open science.
Publishing cutting-edge research in psychiatric neuroscience, cognitive neuroimaging, and global open science.
How does stress-induced activation in the oval nucleus of the bed nucleus of the stria terminalis 🧠 establish a pathway to resilience 💪 against chronic stress-induced depression 😩?
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Stress History Modulates CRF Neurons to Establish Resilience
Cumulative stress is a major risk factor for developing major depressive disorder (MDD), yet not everyone experiencing chronic stress develops MDD. In those who do not, it is unclear at what point,…
www.bpsgos.org
November 21, 2025 at 4:01 PM
How does stress-induced activation in the oval nucleus of the bed nucleus of the stria terminalis 🧠 establish a pathway to resilience 💪 against chronic stress-induced depression 😩?
Find out here 👇
Find out here 👇
How does chronic stress-induced immune dysfunction 🔥 in the brain 🧠 and periphery contribute to psychiatric behavioral changes?
Learn more here ⬇️
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Immunity in rodent models of stress
Chronic stress is a major risk factor for several psychiatric disorders, including major depressive disorder and posttraumatic stress disorder. This review synthesizes rodent-based findings showing…
www.biologicalpsychiatryjournal.com
November 21, 2025 at 1:01 PM
How does chronic stress-induced immune dysfunction 🔥 in the brain 🧠 and periphery contribute to psychiatric behavioral changes?
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How do stress 😩 and schizophrenia 🧠 alter the timing ⏰ of neurovascular coupling 🩸 across brain networks 🕸️?
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Noncanonical EEG-BOLD coupling by default and in schizophrenia
Neuroimaging methods rely on models of neurovascular coupling that assume hemodynamic responses are canonical; evolving seconds after changes in neural activity. However, emerging evidence reveals…
www.biologicalpsychiatrycnni.org
November 20, 2025 at 4:02 PM
How do stress 😩 and schizophrenia 🧠 alter the timing ⏰ of neurovascular coupling 🩸 across brain networks 🕸️?
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How can the visual system 👁️ be used to guide psychosis treatment 🧠 and assess treatment response 📈?
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Vision and Psychosis: A Clinical Translational Perspective
The visual system, as one of the most well-understood components of the central nervous system, offers a unique framework for understanding mechanistic aspects of psychosis. This review explores the…
www.biologicalpsychiatryjournal.com
November 20, 2025 at 1:01 PM
How can the visual system 👁️ be used to guide psychosis treatment 🧠 and assess treatment response 📈?
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How do orexins 🧪 affect stress states 😩 and behavioral responses 🧠?
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Functional Plasticity of Orexin/Hypocretin Neurons Balances Stress States
Orexin/hypocretin (Orx) peptides critically contribute to stress and arousal circuits’ flexibility and equilibrium. New discoveries highlight plasticity of orexin neurons themselves, as well as…
www.biologicalpsychiatryjournal.com
November 19, 2025 at 4:01 PM
How do orexins 🧪 affect stress states 😩 and behavioral responses 🧠?
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Our November issue of Biological Psychiatry: Global Open Science is live!
Current Issue Table of Contents: Biological Psychiatry: Global Open Science
www.bpsgos.org
November 19, 2025 at 1:02 PM
Our November issue of Biological Psychiatry: Global Open Science is live!
How do striatal levels of glutamate & GABA 🧪 associate 🔗 with dopaminergic function ⚡ in antipsychotic-naive first-episode psychosis 🧠?
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The relationship between neuromelanin, glutamate, and GABA in first-episode psychosis: A multimodal magnetic resonance imaging study
In vivo neuroimaging studies documenting the relationship between dopamine and γ-aminobutyric acid (GABA) or glutamate in schizophrenia are scarce and frequently involve patients in chronic phases of…
www.biologicalpsychiatrycnni.org
November 18, 2025 at 1:02 PM
How do striatal levels of glutamate & GABA 🧪 associate 🔗 with dopaminergic function ⚡ in antipsychotic-naive first-episode psychosis 🧠?
Find out here ⬇️
Find out here ⬇️
Reposted by Biological Psychiatry
Join us in congratulating Paul M. Thompson, PhD, a leader in brain imaging and associate director of USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI), who has been selected as the recipient of the 2025 Gold Medal Award from the Society of Biological Psychiatry (SOBP).
Top USC researcher awarded Gold Medal by Society of Biological Psychiatry
Related News Double Victory: Residency Classmates Turned USC Faculty Achieve NIH Funding Success March 21, 2024 From electrical engineering to the inner ear: how Radha Kalluri, PhD, uses the physical ...
keck.usc.edu
September 29, 2025 at 4:43 PM
Join us in congratulating Paul M. Thompson, PhD, a leader in brain imaging and associate director of USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI), who has been selected as the recipient of the 2025 Gold Medal Award from the Society of Biological Psychiatry (SOBP).
Reposted by Biological Psychiatry
We're looking forward to #SOBP2026!
🧠Building Better Brains: From Synapses to Societies
📆When: April 30 – May 2, 2026
📍Where: New York Marriott Marquis, New York City, New York
Join us for an engaging conference featuring the latest advancements in biological psychiatry.
🧠Building Better Brains: From Synapses to Societies
📆When: April 30 – May 2, 2026
📍Where: New York Marriott Marquis, New York City, New York
Join us for an engaging conference featuring the latest advancements in biological psychiatry.
October 16, 2025 at 2:22 PM
We're looking forward to #SOBP2026!
🧠Building Better Brains: From Synapses to Societies
📆When: April 30 – May 2, 2026
📍Where: New York Marriott Marquis, New York City, New York
Join us for an engaging conference featuring the latest advancements in biological psychiatry.
🧠Building Better Brains: From Synapses to Societies
📆When: April 30 – May 2, 2026
📍Where: New York Marriott Marquis, New York City, New York
Join us for an engaging conference featuring the latest advancements in biological psychiatry.
Reposted by Biological Psychiatry
Longitudinal associations of structural and functional brain connectivity with dimensions of psychopathology in adolescence. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.
doi.org/10.1016/j.bp...
doi.org/10.1016/j.bp...
Redirecting
doi.org
October 1, 2025 at 1:15 AM
Longitudinal associations of structural and functional brain connectivity with dimensions of psychopathology in adolescence. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.
doi.org/10.1016/j.bp...
doi.org/10.1016/j.bp...
How does stimulation ⚡ of the frontal cortex 🧠 for anxious depression differentially affect executive function/attention 💡 and threat sensitivity ⚠️?
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Frontal cortex stimulation modulates attentional circuits and increases anxiety potentiated startle in anxious depression
Major depressive disorder (MDD) with comorbid anxiety presents significant treatment challenges, with high relapse rates and suboptimal outcomes. Transcranial direct current stimulation (tDCS) offers…
www.biologicalpsychiatrycnni.org
November 17, 2025 at 1:01 PM
How does stimulation ⚡ of the frontal cortex 🧠 for anxious depression differentially affect executive function/attention 💡 and threat sensitivity ⚠️?
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How do dissociative states affect brain state dynamics 🧠, and do these effects vary if pharmacologically induced 💊 or due to a clinical condition 🏥?
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Brain State Dynamics in Ketamine-Induced Dissociation Resemble Those in PTSD
Dissociation, an altered state of consciousness in which individuals feel detached from their body, environment, and sense of self, is a common feature of Post-Traumatic Stress Disorder (PTSD).…
www.bpsgos.org
November 16, 2025 at 1:00 PM
How do dissociative states affect brain state dynamics 🧠, and do these effects vary if pharmacologically induced 💊 or due to a clinical condition 🏥?
Learn more here ⬇️
Learn more here ⬇️
The latest Biological Psychiatry issue, focused on Social Stress and Psychological Traumas, is now out!
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Check it out ⬇️
November 15, 2025 at 2:01 PM
The latest Biological Psychiatry issue, focused on Social Stress and Psychological Traumas, is now out!
Check it out ⬇️
Check it out ⬇️
Do the associations between irritability 💢 and subcortical volume 🧠 differ between the sexes ♂️♀️ ?
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Sex-Specific Associations of Irritability with Subcortical Brain Volumes
Irritability is transdiagnostic and associated with considerable impairment. The behavioral presentation of irritability may vary with age, sex, and diagnosis. Although inconsistent, clinical…
www.bpsgos.org
November 15, 2025 at 1:00 PM
Do the associations between irritability 💢 and subcortical volume 🧠 differ between the sexes ♂️♀️ ?
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How can we use machine learning and deep learning models 🤖 trained on EEG data 〰️ to diagnose 🩺 dissociative disorders?
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EEG-Based Machine and Deep Learning Approaches for the Diagnosis of Dissociative Disorders: A Comprehensive Review
Dissociative disorders (DDs), including dissociative identity disorder and depersonalization disorder, are complex and often misdiagnosed psychiatric conditions due to their overlapping symptoms with…
www.bpsgos.org
November 14, 2025 at 3:04 PM
How can we use machine learning and deep learning models 🤖 trained on EEG data 〰️ to diagnose 🩺 dissociative disorders?
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How does the immune system 🛡️ contribute to schizophrenia 🧠, and what is the genetic evidence 🧬 for this?
Find out in this review ⬇️
Find out in this review ⬇️
Genetic evidence for a neuro-immune model of schizophrenia
Since the early 1900s, clinical and epidemiological observations have suggested a link between schizophrenia and the immune system, yet genetic evidence for a pathophysiological connection has…
www.biologicalpsychiatryjournal.com
November 14, 2025 at 1:01 PM
How does the immune system 🛡️ contribute to schizophrenia 🧠, and what is the genetic evidence 🧬 for this?
Find out in this review ⬇️
Find out in this review ⬇️
The latest Biological Psychiatry: Cognitive Neuroscience and Neuroimaging issue is now live!
Current Issue Table of Contents: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
www.biologicalpsychiatrycnni.org
November 13, 2025 at 3:38 PM
The latest Biological Psychiatry: Cognitive Neuroscience and Neuroimaging issue is now live!
Reposted by Biological Psychiatry
Looking for a post-bac RA position focused on the brain bases of affective and psychotic illness?
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
November 11, 2025 at 3:48 PM
Looking for a post-bac RA position focused on the brain bases of affective and psychotic illness?
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social
How does cocaine alter small conductance calcium-activated potassium channels (SK channels) in the supplementary motor cortex (M2), and how does this alteration affect the risk of relapse?
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Downregulation of Small Conductance Potassium Channels in Cortical Pyramidal Neurons of the Supplementary Motor Cortex Underlies High Cocaine Seeking Behaviors
Drug relapse remains the primary challenge in treating addiction. Despite substantial research into the neural mechanisms of relapse, particularly in the medial prefrontal cortex associated with drug…
www.biologicalpsychiatryjournal.com
November 11, 2025 at 2:27 PM
How does cocaine alter small conductance calcium-activated potassium channels (SK channels) in the supplementary motor cortex (M2), and how does this alteration affect the risk of relapse?
Find out here ⬇️
Find out here ⬇️
Can a genetic variant 🧬 in the bitter taste receptor gene predict an increased likelihood of women ♀️ switching medications 💊 for insomnia 🌙?
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November 10, 2025 at 3:00 PM
Can a genetic variant 🧬 in the bitter taste receptor gene predict an increased likelihood of women ♀️ switching medications 💊 for insomnia 🌙?
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How do α5-preferring positive 🟢 and negative 🔴 allosteric modulators of GABA receptors influence affective disorders and their treatment 💊?
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A Comparison of Positive and Negative Allosteric Modulators of Alpha5-Containing GABAARs in the Treatment of Affective Disease
Major depressive disorder (MDD) is a common psychiatric disease that significantly impairs quality of life and productivity. Unfortunately, standard monoamine-based therapies are marred by poor…
www.biologicalpsychiatryjournal.com
November 10, 2025 at 1:00 PM
How do α5-preferring positive 🟢 and negative 🔴 allosteric modulators of GABA receptors influence affective disorders and their treatment 💊?
Find out here ⬇️
Find out here ⬇️
How is the fronto-limbic network 🧠 involved in suicidal thoughts and behaviors 🧩 ?
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The role of fronto-limbic network in suicide: a descriptive literature review of neuroimaging studies
Suicide is a complex public health issue characterized by impairments in emotion regulation and cognitive control. Identifying the brain substrates of suicide is critical for developing targeted and…
www.biologicalpsychiatryjournal.com
November 10, 2025 at 12:20 PM
How is the fronto-limbic network 🧠 involved in suicidal thoughts and behaviors 🧩 ?
Find out here ⬇️
Find out here ⬇️
What role does the mineralocorticoid receptor🧠 play in regulating anxiety😟 in response to stress💥, and is this role sex-specific♀️♂️?
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Mineralocorticoid receptor in glutamatergic neurons modulates anxiety exclusively in male mice via regulation of the actin bundling factor FAM107a
Exposure to stressful life events is a major risk factor for many psychiatric disorders. The mineralocorticoid receptor (MR) is a key regulator of the hypothalamic-pituitary-adrenal (HPA) axis, a…
www.bpsgos.org
November 7, 2025 at 3:57 PM
What role does the mineralocorticoid receptor🧠 play in regulating anxiety😟 in response to stress💥, and is this role sex-specific♀️♂️?
Learn more here 👇
Learn more here 👇
How are cerebral gray-white contrast measures 🧠 altered in World Trade Center responders with PTSD, and can these alterations explain symptom severity?
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Reduced gray-white contrast in chronic post-traumatic stress disorder in World Trade Center responders
Following the collapse of the World Trade Center (WTC), many people experienced severe trauma and 23% of WTC responders developed post-traumatic stress disorder (PTSD). We hypothesized gray-white…
www.biologicalpsychiatrycnni.org
November 6, 2025 at 3:44 PM
How are cerebral gray-white contrast measures 🧠 altered in World Trade Center responders with PTSD, and can these alterations explain symptom severity?
Find out here ⬇️
Find out here ⬇️
Who says brilliant scientists can't be amazing artists too? Check out @kathrynmanning.bsky.social's scientific and artistic contributions in our latest CNNI issue! 🧠🎨
Ecstatic about my science AND art being featured in @biologicalpsych.bsky.social CNNI's current issue with @northernthrux.bsky.social painting on the cover and our exciting @theabcdstudy.bsky.social article completed with @catherinealebel.bsky.social www.biologicalpsychiatrycnni.org/current
November 5, 2025 at 3:39 PM
Who says brilliant scientists can't be amazing artists too? Check out @kathrynmanning.bsky.social's scientific and artistic contributions in our latest CNNI issue! 🧠🎨