Sara Valpione 🌻
@saravalpione.bsky.social
Clinical Senior Lecturer, Clinician in Residence, Med Oncology Consultant at Univ. of Manchester & CRUK NBC & Christie; #ESMO UpperGI faculty, #EORTC UGI MRD. #Tcells, #liquid_biopsies, #nanomedicine, #immunotherapy.
Reposted by Sara Valpione 🌻
The Sanger Prize 2026 is open for applications.
A fully funded three-month placement for undergraduate students from low and middle-income countries.
🔗 Apply now: www.sanger.ac.uk/about/study/...
📅 The closing date for applications: 9th January 2026 at 5pm GMT
A fully funded three-month placement for undergraduate students from low and middle-income countries.
🔗 Apply now: www.sanger.ac.uk/about/study/...
📅 The closing date for applications: 9th January 2026 at 5pm GMT
December 4, 2025 at 3:43 PM
The Sanger Prize 2026 is open for applications.
A fully funded three-month placement for undergraduate students from low and middle-income countries.
🔗 Apply now: www.sanger.ac.uk/about/study/...
📅 The closing date for applications: 9th January 2026 at 5pm GMT
A fully funded three-month placement for undergraduate students from low and middle-income countries.
🔗 Apply now: www.sanger.ac.uk/about/study/...
📅 The closing date for applications: 9th January 2026 at 5pm GMT
Reposted by Sara Valpione 🌻
Digital twins for in vivo metabolic flux estimations in patients with brain cancer: Cell Metabolism www.cell.com/cell-metabol...
Digital twins for in vivo metabolic flux estimations in patients with brain cancer
Quantifying metabolic activity in patient tumors could advance personalized cancer
targeting. Meghdadi et al. develop a digital twin framework using machine learning
to quantify metabolic fluxes in ti...
www.cell.com
December 4, 2025 at 3:47 PM
Digital twins for in vivo metabolic flux estimations in patients with brain cancer: Cell Metabolism www.cell.com/cell-metabol...
Reposted by Sara Valpione 🌻
A new tool, developed in part at Manchester, can accurately predict whether the most common form of brain tumour will grow or cause symptoms.
Meningiomas, which account for around 3,500 new cases annually, are often discovered by chance - until now.
www.manchester.ac.uk/about/news/n...
Meningiomas, which account for around 3,500 new cases annually, are often discovered by chance - until now.
www.manchester.ac.uk/about/news/n...
December 3, 2025 at 9:38 AM
A new tool, developed in part at Manchester, can accurately predict whether the most common form of brain tumour will grow or cause symptoms.
Meningiomas, which account for around 3,500 new cases annually, are often discovered by chance - until now.
www.manchester.ac.uk/about/news/n...
Meningiomas, which account for around 3,500 new cases annually, are often discovered by chance - until now.
www.manchester.ac.uk/about/news/n...
Reposted by Sara Valpione 🌻
⏰ Calling all melanoma enthusiasts!
The abstract submission deadline for the inaugural “Lab to Life: Innovations in Melanoma Research Conference UK 2026” has been extended to 19 December 2025!
Happening 12-13 March 2026 at The Midland Hotel, Manchester.
Submit your abstract and register here:
The abstract submission deadline for the inaugural “Lab to Life: Innovations in Melanoma Research Conference UK 2026” has been extended to 19 December 2025!
Happening 12-13 March 2026 at The Midland Hotel, Manchester.
Submit your abstract and register here:
Home
Lab to Life: Innovations in Melanoma is a UK conference in Manchester on cutting-edge melanoma research, translational science and advances in treatments.
sites.manchester.ac.uk
November 30, 2025 at 2:08 PM
⏰ Calling all melanoma enthusiasts!
The abstract submission deadline for the inaugural “Lab to Life: Innovations in Melanoma Research Conference UK 2026” has been extended to 19 December 2025!
Happening 12-13 March 2026 at The Midland Hotel, Manchester.
Submit your abstract and register here:
The abstract submission deadline for the inaugural “Lab to Life: Innovations in Melanoma Research Conference UK 2026” has been extended to 19 December 2025!
Happening 12-13 March 2026 at The Midland Hotel, Manchester.
Submit your abstract and register here:
Reposted by Sara Valpione 🌻
📢 Don’t miss the next Cancer Biology and Medicine talk tomorrow!
DNA repair: translating mechanistic insights towards new cancer therapies
Prof Steve Jackson
📅 Thurs 4 December, 9:30-10:30
📍Seminar rooms 1 & 2, School of Clinical Medicine
All welcome! @cambridge-scm.bsky.social
DNA repair: translating mechanistic insights towards new cancer therapies
Prof Steve Jackson
📅 Thurs 4 December, 9:30-10:30
📍Seminar rooms 1 & 2, School of Clinical Medicine
All welcome! @cambridge-scm.bsky.social
December 3, 2025 at 10:00 AM
📢 Don’t miss the next Cancer Biology and Medicine talk tomorrow!
DNA repair: translating mechanistic insights towards new cancer therapies
Prof Steve Jackson
📅 Thurs 4 December, 9:30-10:30
📍Seminar rooms 1 & 2, School of Clinical Medicine
All welcome! @cambridge-scm.bsky.social
DNA repair: translating mechanistic insights towards new cancer therapies
Prof Steve Jackson
📅 Thurs 4 December, 9:30-10:30
📍Seminar rooms 1 & 2, School of Clinical Medicine
All welcome! @cambridge-scm.bsky.social
Reposted by Sara Valpione 🌻
"Access matters. Opportunity matters. And giving back to the place that gave you a chance matters most of all."
Read the story of Dr Valeed Ghafoor, who studied at UoM with support from the Manchester Access Programme, which helps under-represented students gain entry to university
Read the story of Dr Valeed Ghafoor, who studied at UoM with support from the Manchester Access Programme, which helps under-represented students gain entry to university
🌟 Meet the graduates giving back to Greater Manchester– from supporting young people to improving health & wellbeing.
Their work shows what our universities & local communities can achieve together.
👉 Read the full story: greatermanchesteruniversities.org/news/meet-the-graduates
#GMUniversities
Their work shows what our universities & local communities can achieve together.
👉 Read the full story: greatermanchesteruniversities.org/news/meet-the-graduates
#GMUniversities
Meet the graduates giving back to Greater Manchester — Greater Manchester Universities
From supporting young people to improving health and wellbeing, five graduates show the real impact of our universities working together.
greatermanchesteruniversities.org
December 3, 2025 at 10:18 AM
"Access matters. Opportunity matters. And giving back to the place that gave you a chance matters most of all."
Read the story of Dr Valeed Ghafoor, who studied at UoM with support from the Manchester Access Programme, which helps under-represented students gain entry to university
Read the story of Dr Valeed Ghafoor, who studied at UoM with support from the Manchester Access Programme, which helps under-represented students gain entry to university
Reposted by Sara Valpione 🌻
These are the 10 art classroom rules of Corita Kent (artist, teacher, social justice advocate and nun). They are true for any creative process, especially Rule 8: DON’T TRY TO CREATE AND ANALYZE AT THE SAME TIME. THEY’RE DIFFERENT PROCESSES. (i.e. night science / day science).
December 2, 2025 at 1:50 AM
These are the 10 art classroom rules of Corita Kent (artist, teacher, social justice advocate and nun). They are true for any creative process, especially Rule 8: DON’T TRY TO CREATE AND ANALYZE AT THE SAME TIME. THEY’RE DIFFERENT PROCESSES. (i.e. night science / day science).
Reposted by Sara Valpione 🌻
Deciphering Tumor Microenvironment Dynamics in Tumorigenesis and Lymph Node Metastasis of Esophageal Squamous Cell Carcinoma using Single-Cell RNA Sequencing https://www.biorxiv.org/content/10.1101/2025.11.27.690370v1
December 1, 2025 at 8:46 AM
Deciphering Tumor Microenvironment Dynamics in Tumorigenesis and Lymph Node Metastasis of Esophageal Squamous Cell Carcinoma using Single-Cell RNA Sequencing https://www.biorxiv.org/content/10.1101/2025.11.27.690370v1
Reposted by Sara Valpione 🌻
To learn more about the exhibit you can read this piece written by @kathelse.bsky.social and @aliceangus.bsky.social #ecoimmunology
sites.manchester.ac.uk/lydia-becker...
sites.manchester.ac.uk/lydia-becker...
‘Entangled Stories’ an Eco-immunology ArtScience project
Discover how a chance meeting on the Isle of May sparked a unique ArtScience collaboration between ecoimmunologists and artist Alice Angus. Supported by the BBSRC and BSI, the Entangled Stories projec...
sites.manchester.ac.uk
November 30, 2025 at 2:06 PM
To learn more about the exhibit you can read this piece written by @kathelse.bsky.social and @aliceangus.bsky.social #ecoimmunology
sites.manchester.ac.uk/lydia-becker...
sites.manchester.ac.uk/lydia-becker...
Reposted by Sara Valpione 🌻
Good morning, all. A great selection of papers in #cancermetabolism and #mitochondrialbiology is waiting for you here: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading
"Calm down. Both your sins and your good deeds will be lost in oblivion." - Czesław Miłosz
"Calm down. Both your sins and your good deeds will be lost in oblivion." - Czesław Miłosz
November 30, 2025 at 6:22 AM
Good morning, all. A great selection of papers in #cancermetabolism and #mitochondrialbiology is waiting for you here: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading
"Calm down. Both your sins and your good deeds will be lost in oblivion." - Czesław Miłosz
"Calm down. Both your sins and your good deeds will be lost in oblivion." - Czesław Miłosz
Reposted by Sara Valpione 🌻
Proudly delivered, label-free, in collaboration with @christieinstitute.bsky.social & The Christie Charity.
Limited places - please register early.
Looking forward to seeing many of you there! 🌟
🔗 Event link 👇
Limited places - please register early.
Looking forward to seeing many of you there! 🌟
🔗 Event link 👇
Unlocking TIL Therapy: A New Era for Melanoma Care in the UK
Join us for the Unlocking TIL Therapy: A New Era for Melanoma Care in the UK onsite at The Midland Hotel Manchester
www.eventbrite.co.uk
November 29, 2025 at 11:05 AM
Proudly delivered, label-free, in collaboration with @christieinstitute.bsky.social & The Christie Charity.
Limited places - please register early.
Looking forward to seeing many of you there! 🌟
🔗 Event link 👇
Limited places - please register early.
Looking forward to seeing many of you there! 🌟
🔗 Event link 👇
Reposted by Sara Valpione 🌻
🚀 Save the Date!
We’re excited to launch our flagship TIL Summit in Manchester: "Unlocking TIL Therapy: A New Era for Melanoma Care in the UK"
🗓 11 March 2026
📍 The Midland Hotel, Manchester
We’re excited to launch our flagship TIL Summit in Manchester: "Unlocking TIL Therapy: A New Era for Melanoma Care in the UK"
🗓 11 March 2026
📍 The Midland Hotel, Manchester
November 29, 2025 at 11:05 AM
🚀 Save the Date!
We’re excited to launch our flagship TIL Summit in Manchester: "Unlocking TIL Therapy: A New Era for Melanoma Care in the UK"
🗓 11 March 2026
📍 The Midland Hotel, Manchester
We’re excited to launch our flagship TIL Summit in Manchester: "Unlocking TIL Therapy: A New Era for Melanoma Care in the UK"
🗓 11 March 2026
📍 The Midland Hotel, Manchester
Reposted by Sara Valpione 🌻
🧫How can spatial profiling reveal the hidden organisation of the immune system?
Join this parallel session at #BSI25 to explore how multi-omics and computational biology are uncovering new insights into immune cell interactions!
Register here: https://bit.ly/3IkxWq8
Join this parallel session at #BSI25 to explore how multi-omics and computational biology are uncovering new insights into immune cell interactions!
Register here: https://bit.ly/3IkxWq8
November 12, 2025 at 2:01 PM
🧫How can spatial profiling reveal the hidden organisation of the immune system?
Join this parallel session at #BSI25 to explore how multi-omics and computational biology are uncovering new insights into immune cell interactions!
Register here: https://bit.ly/3IkxWq8
Join this parallel session at #BSI25 to explore how multi-omics and computational biology are uncovering new insights into immune cell interactions!
Register here: https://bit.ly/3IkxWq8
Reposted by Sara Valpione 🌻
New BMJ Research finds that tai chi has similar benefits to cognitive behavioural therapy for middle aged and older people with chronic insomnia
www.bmj.com/content/391/...
www.bmj.com/content/391/...
November 27, 2025 at 10:22 AM
New BMJ Research finds that tai chi has similar benefits to cognitive behavioural therapy for middle aged and older people with chronic insomnia
www.bmj.com/content/391/...
www.bmj.com/content/391/...
Reposted by Sara Valpione 🌻
A bit late to the party on this @science.org piece. I've always been intrigued by how TEs, are so specifically regulated. Mammalian cancers, for instance, often co-opt L1 activity as a potential mutational escape route from stressful environments.
www.science.org/content/arti...
www.science.org/content/arti...
November 29, 2025 at 4:54 PM
A bit late to the party on this @science.org piece. I've always been intrigued by how TEs, are so specifically regulated. Mammalian cancers, for instance, often co-opt L1 activity as a potential mutational escape route from stressful environments.
www.science.org/content/arti...
www.science.org/content/arti...
Reposted by Sara Valpione 🌻
Special issue on "The ecology and evolution of bacterial immune systems." @pradeu.bsky.social @philinbiomed.bsky.social and all the other philosophers interested in immunology, etc.
royalsocietypublishing.org/toc/rstb/202...
royalsocietypublishing.org/toc/rstb/202...
Philosophical Transactions of the Royal Society B: Biological Sciences: Vol 380, No 1934
Can't sign in? Forgot your password?
royalsocietypublishing.org
September 5, 2025 at 2:25 PM
Special issue on "The ecology and evolution of bacterial immune systems." @pradeu.bsky.social @philinbiomed.bsky.social and all the other philosophers interested in immunology, etc.
royalsocietypublishing.org/toc/rstb/202...
royalsocietypublishing.org/toc/rstb/202...
Reposted by Sara Valpione 🌻
Benchmarking deep learning methods for biologically conserved single-cell integration 🧬🖥️ link.springer.com/article/10.1...
Benchmarking deep learning methods for biologically conserved single-cell integration - Genome Biology
Background Advancements in single-cell RNA sequencing have enabled the analysis of millions of cells, but integrating such data across samples and methods while mitigating batch effects remains challe...
link.springer.com
November 28, 2025 at 8:34 PM
Benchmarking deep learning methods for biologically conserved single-cell integration 🧬🖥️ link.springer.com/article/10.1...
Reposted by Sara Valpione 🌻
🔈It's BSI Congress time and we're thrilled that this year's keynote speaker is the Becker's Immuno-matrix Branch Lead and @exposomeimmunology.bsky.social Director @profjudiallen.bsky.social !
#BSI25 #BeckerAtTheBSI #ImmunoSky
#BSI25 #BeckerAtTheBSI #ImmunoSky
📣 #BSI25 programme update
We are sorry to announce that Prof. Yasmine Belkaid will no longer be able to join us at BSI Congress this year. We are, however, delighted to announce our new keynote speaker: Prof. Judi Allen from @manchester.ac.uk!
Find out more here: https://bit.ly/4nm9QKt
We are sorry to announce that Prof. Yasmine Belkaid will no longer be able to join us at BSI Congress this year. We are, however, delighted to announce our new keynote speaker: Prof. Judi Allen from @manchester.ac.uk!
Find out more here: https://bit.ly/4nm9QKt
November 28, 2025 at 8:05 AM
🔈It's BSI Congress time and we're thrilled that this year's keynote speaker is the Becker's Immuno-matrix Branch Lead and @exposomeimmunology.bsky.social Director @profjudiallen.bsky.social !
#BSI25 #BeckerAtTheBSI #ImmunoSky
#BSI25 #BeckerAtTheBSI #ImmunoSky
Reposted by Sara Valpione 🌻
Australia recorded ZERO cases of cervical cancer in women under 25 for the first time since they started tracking the cancer in the 80s.
This is the power of vaccines.
The HPV vaccine is extremely effective at preventing cancer.
Viruses can be oncogenic. Get your vaccines and protect yourself!
This is the power of vaccines.
The HPV vaccine is extremely effective at preventing cancer.
Viruses can be oncogenic. Get your vaccines and protect yourself!
newsGP - Australia set for world-first cervical cancer elimination
Vaccination programs have played a key role, and GPs remain ‘instrumental’ in boosting screening rates to reach the 2035 target.
www1.racgp.org.au
November 27, 2025 at 3:45 AM
Australia recorded ZERO cases of cervical cancer in women under 25 for the first time since they started tracking the cancer in the 80s.
This is the power of vaccines.
The HPV vaccine is extremely effective at preventing cancer.
Viruses can be oncogenic. Get your vaccines and protect yourself!
This is the power of vaccines.
The HPV vaccine is extremely effective at preventing cancer.
Viruses can be oncogenic. Get your vaccines and protect yourself!
Reposted by Sara Valpione 🌻
‘Cancer Detectives: Finding the Cures’ is a gripping new Channel 4 series revealing breakthroughs in cancer prevention, detection & treatment.
Episode 3 features Prof. Caroline Dive (CRUK National Biomarker Centre) & her work on cancer early detection.
Stream all episodes on Channel 4 now.
Episode 3 features Prof. Caroline Dive (CRUK National Biomarker Centre) & her work on cancer early detection.
Stream all episodes on Channel 4 now.
We’re thrilled to partner with Channel 4 on ‘Cancer Detectives: Finding the Cures’ - a new series which is shining a light on three trailblazing scientists taking on cancer, and explores how their work is changing patients’ lives right now. 👇 1/2
November 26, 2025 at 11:51 AM
‘Cancer Detectives: Finding the Cures’ is a gripping new Channel 4 series revealing breakthroughs in cancer prevention, detection & treatment.
Episode 3 features Prof. Caroline Dive (CRUK National Biomarker Centre) & her work on cancer early detection.
Stream all episodes on Channel 4 now.
Episode 3 features Prof. Caroline Dive (CRUK National Biomarker Centre) & her work on cancer early detection.
Stream all episodes on Channel 4 now.
Reposted by Sara Valpione 🌻
Thanks for sharing @mucosalimmunol.bsky.social. This work was led by @lizihegarty.bsky.social during her PhD @edinuni-irr.bsky.social funded by @wellcometrust.bsky.social. Now being continued after our relocation to @uofgsii.bsky.social.
Might be of interest to @emds2025.bsky.social attendees!
Might be of interest to @emds2025.bsky.social attendees!
Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair in this work from @lizihegarty.bsky.social, @bainlab.bsky.social, and colleagues: www.mucosalimmunology.org/article/S193...
November 27, 2025 at 8:52 AM
Thanks for sharing @mucosalimmunol.bsky.social. This work was led by @lizihegarty.bsky.social during her PhD @edinuni-irr.bsky.social funded by @wellcometrust.bsky.social. Now being continued after our relocation to @uofgsii.bsky.social.
Might be of interest to @emds2025.bsky.social attendees!
Might be of interest to @emds2025.bsky.social attendees!
Reposted by Sara Valpione 🌻
📣 Last call‼️
🚀 Are you ready to take your career to the next level❓
💡 8–10 fully funded PhD fellowships open for Life Sciences & Medical students!
Apply now and be the next to turn cancer discoveries into cures 👉 https://linke.to/PhDfellowships25_VHIO
📅 Deadline: 28 November
#SOMMVHIO
🚀 Are you ready to take your career to the next level❓
💡 8–10 fully funded PhD fellowships open for Life Sciences & Medical students!
Apply now and be the next to turn cancer discoveries into cures 👉 https://linke.to/PhDfellowships25_VHIO
📅 Deadline: 28 November
#SOMMVHIO
November 27, 2025 at 9:03 AM
📣 Last call‼️
🚀 Are you ready to take your career to the next level❓
💡 8–10 fully funded PhD fellowships open for Life Sciences & Medical students!
Apply now and be the next to turn cancer discoveries into cures 👉 https://linke.to/PhDfellowships25_VHIO
📅 Deadline: 28 November
#SOMMVHIO
🚀 Are you ready to take your career to the next level❓
💡 8–10 fully funded PhD fellowships open for Life Sciences & Medical students!
Apply now and be the next to turn cancer discoveries into cures 👉 https://linke.to/PhDfellowships25_VHIO
📅 Deadline: 28 November
#SOMMVHIO
Reposted by Sara Valpione 🌻
Reposted by Sara Valpione 🌻
FDA Approval for durvalumab combined with FLOT in #GastricCancer
Based on MATTEHORN
Source: AstraZeneca
www.astrazeneca.com/media-centre...
Durvalumab combined wi/ FLOT chemotherapy has received US approval for treating adults with resectable, early to locally advanced gastric and GEJ cancers
Based on MATTEHORN
Source: AstraZeneca
www.astrazeneca.com/media-centre...
Durvalumab combined wi/ FLOT chemotherapy has received US approval for treating adults with resectable, early to locally advanced gastric and GEJ cancers
November 25, 2025 at 7:29 PM
FDA Approval for durvalumab combined with FLOT in #GastricCancer
Based on MATTEHORN
Source: AstraZeneca
www.astrazeneca.com/media-centre...
Durvalumab combined wi/ FLOT chemotherapy has received US approval for treating adults with resectable, early to locally advanced gastric and GEJ cancers
Based on MATTEHORN
Source: AstraZeneca
www.astrazeneca.com/media-centre...
Durvalumab combined wi/ FLOT chemotherapy has received US approval for treating adults with resectable, early to locally advanced gastric and GEJ cancers