Calum Bain
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bainlab.bsky.social
Calum Bain
@bainlab.bsky.social
Scottish Immunologist based in The School of Infection & Immunity at The University of Glasgow.

Honorary Fellow at The Institute for Regeneration and Repair at The University of Edinburgh.
Reposted by Calum Bain
#Neutrophils are short lived cells, yet in ARDS display long term changes, with impaired neutrophil functions even after 6 months. How can they undergo long term reprogramming?

this is what @mas-g.bsky.social answered, mapping changes to neut. progenitors. @walmsley-lab.bsky.social #immunosky
Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity - Nature Immunology
Walmsley and colleagues report that systemic hypoxia induces persistent loss of histone H3K4me3 marks and epigenetic reprogramming in neutrophil progenitors, resulting in long-term impairment of subse...
www.nature.com
October 28, 2025 at 11:55 AM
Reposted by Calum Bain
🆕 | @uofgsii.bsky.social researchers played a key role in delivering the 38th EMDS meeting, held 16–18 Sep in Edinburgh.

Led by @bainlab.bsky.social and @mariolaks.bsky.social with colleagues at @edinburghuni.bsky.social, the event hosted over 260 delegates.

🔗 More: www.gla.ac.uk/schools/infe...
October 23, 2025 at 10:35 AM
Did you attend #EMDS2025? If so, please take time to tell us about your experience in the survey you received. This will help the organisers of #EMDS2026 (Amsterdam, November 2026)

@edinuni-irr.bsky.social
@britsocimm.bsky.social
The sun has set on #EMDS2025 but be sure to complete the survey sent out last week. We need your feedback, good or bad, to ensure that future meetings reflect your priorities and address any concerns.

@britsocimm.bsky.social
@efis-immunology.bsky.social

Photo credit: Becky Dempsey
September 27, 2025 at 7:02 AM
Well done @lizihegarty.bsky.social. You are an exemplar postdoc - hardworking, well-read, conscientious, supportive, collegiate, all while being good fun (and expert in where to dine!!). Delighted to have you as a colleague.

@edinuni-irr.bsky.social
@uofgsii.bsky.social
@britsocimm.bsky.social
Absolutely delighted that our superstar #postdoc @lizihegarty.bsky.social was awarded the @cmvm-edinburghuni.bsky.social Student Support & Supervision Award for #PAW 2025. Thoroughly deserved for everything she does for @emmersonlab-irr.bsky.social, @bainlab.bsky.social & @edinuni-irr.bsky.social
September 23, 2025 at 9:05 AM
Reposted by Calum Bain
Great to see this out for all to see after a lot of hard work by @lizihegarty.bsky.social and @bainlab.bsky.social. Colonic #macrophages persist but are transcriptionally altered post- #inflammation in a mouse model of #colitis.
Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair https://www.biorxiv.org/content/10.1101/2025.09.19.677333v1
September 22, 2025 at 6:48 AM
Delighted all of @lizihegarty.bsky.social's hard work as paid off. She shows that tissue resident colonic #macrophages persist through #inflammation and adapt to aid tissue repair.

Lovely collaborative work with colleagues @edinuni-irr.bsky.social and beyond. 🙏🏻

@uofgsii.bsky.social
Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair https://www.biorxiv.org/content/10.1101/2025.09.19.677333v1
September 23, 2025 at 9:00 AM
Amazing! Well done @lizihegarty.bsky.social. Thoroughly deserved. You contribute so much to the Emmerson and Bain labs.

@edinuni-irr.bsky.social
@uofgsii.bsky.social
Absolutely delighted that our superstar #postdoc @lizihegarty.bsky.social was awarded the @cmvm-edinburghuni.bsky.social Student Support & Supervision Award for #PAW 2025. Thoroughly deserved for everything she does for @emmersonlab-irr.bsky.social, @bainlab.bsky.social & @edinuni-irr.bsky.social
September 20, 2025 at 7:49 AM
Reposted by Calum Bain
📣 Journal Editors at EMDS2025:Scotland Edition

Giuliana Clemente, Associate Editor (Immunology) @natcomms.nature.com, will be in Edinburgh at #EMDS2025 this week. Reach out to her to discuss your work.

@efis-immunology.bsky.social
@britsocimm.bsky.social
September 14, 2025 at 10:11 AM
Reposted by Calum Bain
We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...
Research Associate in in Neuro-Immunology and Extraceullar Matrix Biology (ImmunoMatrix):Oxford Road
Our Glyco-Immunology (Dyer) lab has produced published and preliminary data demonstrating that an under-appreciated structure, the glycocalyx, on endothelial- and immune- cells regulates immune cell recruitment by:
www.jobs.manchester.ac.uk
September 12, 2025 at 3:47 PM
Reposted by Calum Bain
📣 Journal Editors at EMDS2025:Scotland Edition

@gaiajexpmed.bsky.social, Deputy Editor @jem.org, will be in Edinburgh at #EMDS2025 next week. Reach out to her to discuss your work. Also, check out the Special Collection @jem.org on #macrophage & #dendriticcells

@efis-immunology.bsky.social
September 12, 2025 at 6:51 AM
Reposted by Calum Bain
📣 Journal Editors at #EMDS2025

@claireolingy.bsky.social , Senior Editor at #Science #Immunology @aaas.org , will be at EMDS2025, so be sure to reach out to her to discuss your work.

@efis-immunology.bsky.social @britsocimm.bsky.social
September 11, 2025 at 11:25 AM
Reposted by Calum Bain
Another exciting opportunity @dunnschool.bsky.social !

Come and be a colleague to a great group of scientists working on the fundamental mechanisms underlying disease, and how to transform health

Please help us find great applicants
We're hiring (again)!

We are looking for an associate professor in cell and molecular biology, with a particular focus on immunology (defined broadly)

If you have a great record and exciting plans, consider joining our thriving and welcoming department

www.path.ox.ac.uk/vacancy/asso...
September 10, 2025 at 1:34 PM
Reposted by Calum Bain
Speaker Highlight - William (Bill) Agace

It's not too late to join us at #EMDS2025 to hear from Bill Agace about their work dissecting dendritic cell diversity in #Crohn's disease.

www.emds2025.com

@britsocimm.bsky.social @efis-immunology.bsky.social

[Background photo: Andrew Perry]
September 9, 2025 at 1:01 PM
Still time to register for #EMDS2025 in the wonderful city of Edinburgh!

All details including invited & selected speakers and their abstract details at www.emds2025.com

Plus, the chance to take part in a traditional ceilidh!
August 28, 2025 at 12:16 PM
Reposted by Calum Bain
The #Travel4Expertise Grant offers up to USD 2,500 to support care-related costs while you travel for hands-on training or advanced techniques.
🔗 Learn more and apply: https://loom.ly/en-kO9s
#GlobalImmunology #GenderEquity #ImmunologyWithoutBorders
August 25, 2025 at 12:02 PM
Reposted by Calum Bain
Speaker Highlight - Clare Bennett

Join us at #EMDS2025 to hear from @clarebennettslab.bsky.social from @ucl.ac.uk about the curious case of the Langerhans cell - DC or #macrophage?

Register today at www.emds2025.com

@efis-immunology.bsky.social
August 25, 2025 at 12:45 PM
Reposted by Calum Bain
Speaker Highlight - Samanta Mariani

#Macrophages support #HSC development in health but what happens in the context of leukaemia? Join us at #EMDS2025 to hear from Samanta Mariani from @edinuni-irr.bsky.social to find out more. Register today at www.emds2025.com

@efis-immunology.bsky.social
August 21, 2025 at 7:54 AM
Reposted by Calum Bain
August 19, 2025 at 6:33 AM
Looking forward to catching up @martinguilliams.bsky.social and hearing what you and the group have been up to.
Honoured to be opening EMDS2025!!! What a superb program! See you all in Scotland 🤩🤩🤩🤩🤩🤩
August 18, 2025 at 4:01 PM
Reposted by Calum Bain
Join the West of Scotland Immunology community on Thurs 2 October in Glasgow for cutting-edge research & the Delphine Parrott memorial lecture.

Enjoy inspiring talks, interactive posters, networking & more. #BSIWSIG25

Submit your abstract & register: https://bit.ly/4oyR7gx
August 18, 2025 at 10:00 AM
Reposted by Calum Bain
Speaker Highlight - James Lee

Don't miss James Lee from @crick.ac.uk at #EMDS2025 - he will tell us about how understanding of human genetics in inflammatory disease is uncovering new facets of macrophage biology.

Reg. & late breaking abstracts OPEN at www.emds2025.com

@britsocimm.bsky.social
August 15, 2025 at 5:23 AM
Reposted by Calum Bain
Super proud that my PhD paper is finally out! doi.org/10.1111/all.... RSV leaves long-lasting marks on the lung, potentially boosting future immune responses but also contributing to allergen sensitisation.
Epithelial Memory After Respiratory Viral Infection in Mice Results in Prolonged Enhancement of Antigen Presentation
RSV infection induces lasting epigenetic and transcriptional changes in LECs, upregulating MHC-I and MHC-II, further amplified by LPS exposure. This is accompanied by increased antigen uptake, proc...
doi.org
August 12, 2025 at 10:21 AM
Reposted by Calum Bain
Speaker Highlight - Bernhard Gentner

Join us at #EMDS2025 to hear how the Gentner group genetically engineer haematopoietic cells to rewire anti-tumour immunity!

Registration OPEN at www.emds2025.com

@britsocimm.bsky.social
@edinuni-irr.bsky.social
August 11, 2025 at 9:53 AM
Reposted by Calum Bain
You asked, we listened!

We have had multiple requests for late breaking abstracts for #EMDS2025. So, we have managed to squeeze in 15 more opportunities for poster presentation.

Submit your abstract at www.emds2025.com - first come, first served.

Deadline: 22.08.25 (or when 15 slots allocated!)
August 6, 2025 at 6:37 AM
July 30, 2025 at 5:44 AM